• Journal of radiological science and technology
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• v.39 no.2
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• pp.157-161
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• 2016

The purpose of this study is that in measures the acoustic propagate characteristics and temperature sensitivity of ultrasound tissue mimicking phantom(TM phantom). TM phantom manufacture according to the International Electronical Committee(IEC) guidelines for acoustic propagate characteristics of soft tissue. TM phantom was observed to have the image brightness and the image depth penetration decreases changes convergence which was the subject of ultrasound image characteristics in accordance with an external temperature that the change is reduced in temperature below $22^{\circ}C$. This study provide a basis t o create another TM Phantom and TM Phantom has been determined that it is appropriate for use in more than $22^{\circ}C$.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.1
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• pp.91-97
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• 2015

PURPOSE: In this study investigated the thermal effect in tissue mimicking phantom by the material of the ultrasonic transducer in low intensity sonication. METHODS: The material of the ultrasonic transducer was made of ceramic, stainless steel, aluminum. Korea Testing Laboratory was measured of the three kinds of materials the total output of the ultrasonic transducer. Each material was measured core temperature and the actual output depending on the type of transducer. Agarose tissue mimicking phantom and silicone tissue mimicking phantom was made. Transducers made of three kinds of materials were emitted in the phantom. It is shown as a graph about time and temperature and the surface temperature rising speed and deep temperature rise rate was investigated. RESULTS: Ceramic transducers were highest output. Higher than the stainless steel transducer, aluminum had the lowest total output. Deep temperature was the highest in the ceramic transducer, and the surface temperature was the highest in the stainless steel transducer. Thermal images of ceramic transducer showed that a valid output is formed deeper wider than the metal. CONCLUSION: Ceramic transducer is confirmed the excellence than the metal transducer in deep thermal effect and the actual output of the ultrasound.

• The Journal of the Acoustical Society of Korea
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• v.33 no.5
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• pp.291-299
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• 2014

To probe the temperature elevation effect caused by ultrasound, a tissue mimicking phantom was newly suggested. A carrageenan gel was adopted to realize not only the required transparency for visualization but also acoustic characteristics similar to human tissue. To visualize the temperature elevation inside phantom, thermochromic film with a critical temperature of discoloration was introduced. Acoustic characteristics of the tissue mimicking phantom were examined when the concentrations of carrageenan and sucrose changed. As the results, the attenuation coefficient of the phantom could be controlled in the range of 0.44~0.49 dB/cm/MHz, and the acoustic impedance in the range of 1.52~1.77 Mrayls. We could control the acoustic characteristics of the phantom by different concentration of carrageenan and sucrose, and it was possible to examine the temperature elevation caused by ultrasound in the phantom. The suggested method was verified by noninvasively visualizing the temperature elevation due to planar and focused ultrasound using the fabricated phantom.

• Journal of the Korean Physical Society
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• v.73 no.9
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• pp.1289-1294
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• 2018

The present study aims to investigate experimentally and theoretically thermal ablation in soft tissues by using high intensity focused ultrasound (HIFU) to assess tissue damage during HIFU thermotherapy. The HIFU field was calculated by solving the axisymmetric Khokhlov-Zabolotskaya-Kuznetsov equation from the frequency-domain perspective. The temperature field was calculated by solving Pennes' bioheat transfer equation, and the thermal dose required to create a thermal lesion was calculated by using the thermal dose formula based on the thermal dose of a 240-min exposure at $43^{\circ}C$. In order to validate the simulation results, we performed thermal ablation experiments in a tissue-mimicking phantom and ex-vivo porcine liver for two different HIFU source conditions by using a 1.1-MHz, single-element, spherically focused HIFU transducer. The small difference between the measured and the predicted lesion sizes suggests that the implementation of the numerical model used here should be modified to iteratively allow for temperature-dependent changes in the physical properties of tissues.

• Journal of radiological science and technology
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• v.26 no.1
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• pp.51-62
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• 2003

We carried out studies on develop of the ultrasound tissue mimicking materials(TMM) by synthesis of polymer urethane(C, CCR, $TiO_2$, tungsten, graphite, silver type). The major finding were as follows; (1) C type TMM was shown good homogeneity, penetration, gray scale like as liver tissue and propagated speed 1,540 m/s, attenuation $0.5{\sim}0.7\;dB/cm/MHz$. (2) $TiO_2$ type TMM was shown heterogeneous dot echo pattern. (3) Silver type TMM was appear good homogeneous echo pattern like as echo texture of thyroid gland. Therefor, C type TMM will be useful for ultrasound Q/A phantom materials and previous phantom materials.

• ETRI Journal
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• v.41 no.6
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• pp.850-862
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• 2019

This work investigated three-dimensional (3D) focused microwave thermotherapy (FMT) at 925 MHz for a human tissue mimicking phantom using the time reversal (TR) principle for musculoskeletal disorders. We verified the proposed TR algorithm by evaluating the possibility of 3D beam focusing through simulations and experiments. The simulation, along with the electromagnetic and thermal analyses of the human tissue mimicking phantom model, was conducted by employing the Sim4Life commercial tool. Experimental validation was conducted on the developed FMT system using a fabricated human tissue mimicking phantom. A truncated threshold method was proposed to reduce the unwanted hot spots in a normal tissue region, wherein a beam was appropriately focused on a target position. The validation results of the simulation and experiments obtained by utilizing the proposed TR algorithm were shown to be acceptable. Effective beam focusing at the desired position of the phantom could be achieved.

• IEIE Transactions on Smart Processing and Computing
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• v.3 no.1
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• pp.28-34
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• 2014

Recently, ultrasound therapy has become a new and effective treatment for many brain diseases. Therefore, skull-mimicking phantoms have been developed to simulate the skull and brain tissue of a human and allow further research into ultrasound therapy. In this study, the suitability of various skull-mimicking materials(HDPE, POM C, Acrylic) for studies of brain-tumor treatments was evaluated using focused ultrasound. The acoustic properties of three synthetic resins were measured. The skull-mimicking materials were then combined with an egg white phantom to observe the differences in the ultrasound beam distortion according to the type of material. High-intensity polyethylene was found to be suitable as a skull-mimicking phantom because it had acoustic properties and a denatured-area shape that was close to those of the skull,. In this study, a skull-mimicking phantom with a multi-layer structure was produced after evaluating several skull-mimicking materials. This made it possible to predict the denaturation in a skull in relation to focused ultrasound. The development of a therapeutic protocol for a range of brain diseases will be useful in the future.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.4
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• pp.368-373
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• 2009

A human tissue mimicking phantom is constructed to assess the performance of a medical ultrasound elasticity imaging system. In a human body, the tumor or cancer is stiffer than its surrounding normal tissue. A technique fur imaging the elasticity of such a tissue is referred to as elastography. Homogeneous elasticity phantoms with differing Young's moduli are constructed using a plastic hardener and softener to simulate the mechanical characteristics of a diseased human tissue. The Young's modulus of the fabricated homogeneous phantom materials were measured from 11.1 to 79.6 kPa depending on the mixing ratio of the amount of the hardener to that of the softener. An ultrasound lesion mimicking phantom was made of these materials, and ultrasound elasticity imaging was performed on it. It is confirmed in this paper that the fabricated plastic-based elasticity phantom is useful in representing the elastic characteristics of a human tissue.

• Journal of the Korean Society of Radiology
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• v.7 no.6
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• pp.433-439
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• 2013

In this study, human head-mimicking phantom was developed for brain disease treatment study using focused ultrasound. Acoustic parameters of skin, skull and brain were investigated through literature investigation and adequate substitutes according to each tissue were suggested. In the case of skin phantom, construction ratio of glycerol-based TMM phantom was controlled to mimic real skin. The suitability of skull substitutes was evaluated through measurement of acoustic parameters. In the case of brain phantom, transparent egg white phantom was used to observe thermal properties of focused ultrasound. Combined human-head-mimicking phantom using each substitutes was fabricated for development of brain disease treatment protocol. Denaturation of brain phantom according to ultrasonic condition was observed for validation.

• Nuclear Engineering and Technology
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• v.53 no.12
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• pp.4158-4165
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• 2021

In this study, tissue equivalency (TE) of a newly developed epoxy-based phantom to 3-5 years child's tissue was investigated in paediatric energy range. Epoxy-based TE-phantoms were produced at different glandular/adipose (G/A) ratios of 17/83%, 31/69%, 36/64% and 10/90%. A procedure was developed in which specific amounts of boron, calcium, magnesium, sulphur compounds are mixed with epoxy resin, together with other minor substitutes. In paediatric energy range of 40-60 kV_p half-value layer (HVL) values were measured and then Hounsfield Units (HU) were determined from Computed Tomography(CT) scans taken in the X-ray energy range of 80-120kV_p. It is found that radiation absorption properties of these phantoms in terms of the measured HVL values related to linear attenuation coefficients (µ) are very well mimicking a 3 years child's soft tissue in case a ratio of 10/90%G/A. Additionally, the HU values of phantoms were determined from the CT scans. The HU = 47.8 ± 4.8 value was found for the epoxy-based phantom produced at a ratio of 10/90%G/A. The obtained HVL and HU values also support the suitability of the new epoxy based-phantom produced at a ratio of 10/90%G/A for a satisfactory mimicking a 3 years child's soft tissue by 5%. Thus they can have a potential use to perform the quality controls of medical X-ray systems and dose optimization studies.