• 지질공학
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• 제31권3호
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• pp.257-267
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• 2021

Constraints on the structure and composition of the active layer are important for understanding permafrost evolution. Soil convection owing to repeated moisture-induced freeze-thaw cycles within the active layer promotes the formation of self-organized patterned ground. Here we present the results of ground penetrating radar (GPR) surveys across a selected sorted circle near King Sejong Station, Antarctica, to better delineate the active layer and its relation to the observed patterned ground structure. We acquire GPR data in both bistatic mode (common mid-points) for precise velocity constraints and monostatic mode (common-offset) for subsurface imaging. Reflections are derived from the active layer-permafrost boundary, organic layer-weathered soil boundary within the active layer, and frozen rock-fracture-filled ice boundary within the permafrost. The base of the imaged sorted circle possesses a convex-down shape in the central silty zone, which is typical for the pattern associated with convection-like soil motion within the active layer. The boundary between the central fine-silty domain and coarse-grained stone border is effectively identified in a radar amplitude contour at the assumed active layer depth, and is further examined in the frequency spectra of the near- and far-offset traces. The far-offset traces and the traces from the lower frequency components dominant on the far-offset traces would be associated with rapid absorption of higher frequency radiowave due to the voids in gravel-rich zone. The presented correlation strategies for analyzing very shallow, thin-layered GPR reflection data can potentially be applied to the various types of patterned ground, particularly for acquiring time-lapse imaging, when electric resistivity tomography is incorporated into the analysis.

• Journal of Microbiology and Biotechnology
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• 제31권11호
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• pp.1591-1600
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• 2021

Streptomyces coelicolor is a filamentous soil bacterium producing several kinds of antibiotics. S. coelicolor abs8752 is an abs (antibiotic synthesis deficient)-type mutation at the absR locus; it is characterized by an incapacity to produce any of the four antibiotics synthesized by its parental strain J1501. A chromosomal DNA fragment from S. coelicolor J1501, capable of complementing the abs- phenotype of the abs8752 mutant, was cloned and analyzed. DNA sequencing revealed that two complete ORFs (SCO6992 and SCO6993) were present in opposite directions in the clone. Introduction of SCO6992 in the mutant strain resulted in a remarkable increase in the production of two pigmented antibiotics, actinorhodin and undecylprodigiosin, in S. coelicolor J1501 and abs8752. However, introduction of SCO6993 did not show any significant difference compared to the control, suggesting that SCO6992 is primarily involved in stimulating the biosynthesis of antibiotics in S. coelicolor. In silico analysis of SCO6992 (359 aa, 39.5 kDa) revealed that sequences homologous to SCO6992 were all annotated as hypothetical proteins. Although a metalloprotease domain with a conserved metal-binding motif was found in SCO6992, the recombinant rSCO6992 did not show any protease activity. Instead, it showed very strong β-glucuronidase activity in an API ZYM assay and toward two artificial substrates, p-nitrophenyl-β-D-glucuronide and AS-BI-β-D-glucuronide. The binding between rSCO6992 and Zn²⁺ was confirmed by circular dichroism spectroscopy. We report for the first time that SCO6992 is a novel protein with β-glucuronidase activity, that has a distinct primary structure and physiological role from those of previously reported β-glucuronidases.

• 한국정보통신학회논문지
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• 제25권11호
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• pp.1619-1626
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• 2021

증분형 아날로그 디지털 변환기는 전통적인 델타 시그마 아날로그 디지털 컨버터와 달리 리셋 동작을 통한 입력과 출력의 1:1 매핑이 가능하며 이는 멀티플렉싱에 매우 용이하게 사용될 수 있다. 또한, 증분형 아날로그 디지털 변화기는 전통적인 델타 시그마 변환기에 비해 간단한 디지털 필터 설계가 가능하다. 따라서, 본 논문에서는 아날로그 디지털 컨버터 설계에 기본이 되는 딜레이가 있는 적분기와 딜레이가 없는 적분기의 시간 영역에서의 분석을 시작으로 2차 입력 피드 포워드, 확장된 카운팅, 2+1 매쉬, 2+2 매쉬 구조를 갖는 증분형 아날로그 디지털 변환기의 설계 방정식을 유도한다. 이를 통해 설계 이전에 증분형 아날로그 디지털 변환기의 성능을 예측할 수 있을 뿐만 아니라 각각의 아날로그 디지털 변화기에 적합한 디지털 필터를 설계할 수 있다. 또한, 아날로그 디지털 변환기의 정확도를 향상 시키기 위한 확장된 카운팅, MASH의 설계 기술들을 제안하였다.

• Steel and Composite Structures
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• 제43권1호
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• pp.79-90
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• 2022

In this study, the dynamic behavior of functionally graded layered deep beams with viscoelastic core is investigated including the porosity effect. The material properties of functionally graded layers are assumed to vary continuously through thickness direction according to the power-law function. To investigate porosity effect in functionally graded layers, three different distribution models are considered. The viscoelastically cored deep beam is exposed to harmonic sinusoidal load. The composite beam is modeled based on plane stress assumption. The dynamic equations of motion of the composite beam are derived based on the Hamilton principle. Within the framework of the finite element method (FEM), 2D twelve -node plane element is exploited to discretize the space domain. The discretized finite element model is solved using the Newmark average acceleration technique. The validity of the developed procedure is demonstrated by comparing the obtained results and good agreement is detected. Parametric studies are conducted to demonstrate the applicability of the developed methodology to study and analyze the dynamic response of viscoelastically cored porous functionally graded deep beams. Effects of viscoelastic parameter, porosity parameter, graduation index on the dynamic behavior of porous functionally graded deep beams with viscoelastic core are investigated and discussed. Material damping and porosity have a significant effect on the forced vibration response under harmonic excitation force. Increasing the material viscosity parameters results in decreasing the vibrational amplitudes and increasing the vibration time period due to increasing damping effect. Obtained results are supportive for the design and manufacturing of such type of composite beam structures.

• Smart Structures and Systems
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• 제29권2호
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• pp.267-278
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• 2022

Pre-stressed concrete circular spun piles are widely used in various infrastructure projects around the world and offer an economical deep foundation system with consistent and superior quality compared to cast in-situ and other concrete piles. Conventional methods for measuring the lateral response of piles have been limited to conventional instrumentation, such as electrical based gauges and pressure transducers. The problem with existing technology is that the sensors are not able to assist in recording the lateral stiffness changes of the pile which varies along the length depending on the distribution of the flexural moments and appearance of tensile cracks. This paper describes a full-scale bending test of a 1-m diameter spun pile of 30 m long and instrumented using advanced fibre optic distributed sensor, known as Brillouin Optical Time Domain Analysis (BOTDA). Optical fibre sensors were embedded inside the concrete during the manufacturing stage and attached on the concrete surface in order to measure the pile's full-length flexural behaviour under the prescribed serviceability and ultimate limit state. The relationship between moments-deflections and bending moments-curvatures are examined with respect to the lateral forces. Tensile cracks were measured and compared with the peak strains observed from BOTDA data which corroborated very well. By analysing the moment-curvature response of the pile, the structure can be represented by two bending stiffness parameters, namely the pre-yield (EI) and post-yield (EI_cr), where the cracks reduce the stiffness property by 89%. The pile deflection profile can be attained from optical fibre data through closed-form solutions, which generally matched with the displacements recorded by Linear Voltage Displacement Transducers (LVDTs).

• 문화기술의 융합
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• 제8권6호
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• pp.637-646
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• 2022

본 논문은 한국어의 겹받침 발음에 대하여 베트남인 한국어 학습자와 한국인을 비교 연구하였다. 언어학적인 연구를 통하여 조사하고 분석한 겹받침 발음에 관한 여러 오류와 제시한 교육 방법에 대하여 공학적 특히 음성 신호처리의 분석 방법을 활용하여서 이런 연구 결과를 확인하였고 이에 우리는 본 논문에서 새로운 교육 방법을 제시하였다. 인공지능의 기계 학습에 많이 활용되고 있는 서포팅 벡터 머신 (supporting vector machine, SVM)을 사용하여서 베트남인 학습자의 발음과 한국인의 발음을 비교하였다. SVM의 초결정 평면을 구할 수 있다는 것은 베트남인 학습자의 겹받침 발음이 한국인의 발음과 차이를 보인다는 것이고, 그 반대라면 발음을 잘하고 있다는 것이다. 본 논문에서 우리가 제시한 새로운 교육 방법은 쓰기와 듣기로만 구성하는 것이 아닌 음성 신호의 시간 영역에서 파형과 그것에 대응하는 신호의 에너지 등과 같은 피교육자에게 보일 수 있는 것들을 포함하는 효율적인 발음 교육 방법이다.

• 대한물리의학회지
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• 제17권2호
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• pp.41-51
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• 2022

PURPOSE: The functional limitations in stroke survivors promote sedentary lifestyles and quality of life inadequacies, but there is increasing evidence that this could be minimized by physical exercise. Therefore, this study examined the effects of physical exercise on the quality of life (QoL) and functional capacity (ability to stand up from a sitting position) among stroke survivors drafted from two tertiary hospitals in Osogbo, Nigeria. METHODS: A purposive sampling technique was used to select 21 registered right or left outpatient hemiplegic stroke survivors in a pre- and post-test experimental research design. The research questions were presented using descriptive statistics of frequency, percentage, mean and standard deviation, while an Analysis of Variance (ANOVA) was used to test the study hypothesis at the .05 alpha level for significance. RESULTS: Compared to the baseline (week 0), there were significant increases in the general quality of life, healthy well-being, physical exercise, pain perception, and environmental domains of QOL among the survivors in week four. Moreover, a significant increase was observed in these indices in week eight, compared to week four, except for the pain perception domain. Compared to the baseline, there was a significant decrease in the time it took the stroke survivors to stand up from a sitting position in week four. A significant decrease was observed in this index in week eight compared to week four. CONCLUSION: Marked corridor 20 meters brief walking exercise for eight weeks significantly improved the quality of life and ability to stand up from a sitting position in stroke survivors in Osogbo, Nigeria.

• 한국인공지능학회지
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• 제11권4호
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• pp.9-13
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• 2023

In this study, we explored the potential of integrating interactive AI callbot technology into the medical consultation domain as part of a broader service development initiative. Aimed at enhancing patient satisfaction, the AI callbot was designed to efficiently address queries from hospitals' primary users, especially the elderly and those using phone services. By incorporating an AI-driven callbot into the hospital's customer service center, routine tasks such as appointment modifications and cancellations were efficiently managed by the AI Callbot Agent. On the other hand, tasks requiring more detailed attention or specialization were addressed by Human Agents, ensuring a balanced and collaborative approach. The deep learning model for voice recognition for this study was based on the Transformer model and fine-tuned to fit the medical field using a pre-trained model. Existing recording files were converted into learning data to perform SSL(self-supervised learning) Model was implemented. The ANN (Artificial neural network) neural network model was used to analyze voice signals and interpret them as text, and after actual application, the intent was enriched through reinforcement learning to continuously improve accuracy. In the case of TTS(Text To Speech), the Transformer model was applied to Text Analysis, Acoustic model, and Vocoder, and Google's Natural Language API was applied to recognize intent. As the research progresses, there are challenges to solve, such as interconnection issues between various EMR providers, problems with doctor's time slots, problems with two or more hospital appointments, and problems with patient use. However, there are specialized problems that are easy to make reservations. Implementation of the callbot service in hospitals appears to be applicable immediately.

• 문화기술의 융합
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• 제10권2호
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• pp.67-71
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• 2024

莫友芝(모유지)(1811-1871)는 청나라 말기의 저명한 학자, 시인, 서예가이다. 모유지는 일생 동안 경력이 풍부하고 시야가 넓으며 특히 증국 번 막부에 들어간 10년 동안 많은 정치, 문화 엘리트를 사귀었다. 모유지는 총명하고 부지런하며 학문에 열중했으며 당시 각계각층의 유명인들과 교유할 수 있는 기회가 있어 재능을 충분히 발휘했다. 청대에는 금석학이 전례 없이 번영했고, 서예에서는 비학(碑學)이 서단의 절대적인 주도가 되었으며, 전예서는 진한(汉漢) 이후 처음으로 크게 번영하였다. 시대에 순응한 모유지는 학문에 몰두하고 한묵을 돌보며 자신만의 서예의 길을 걷는것이 사실이다. 그의 글씨 중 전서, 예서, 해서, 행, 특히 전서 예서가 정교하다. 본 고는 예서를 바탕으로 전형적인 풍격과 비정형 형태을 각각 설명하고 예서와 다른 서체 간의 관계에 대해서도 간략하게 논의한다. 마지막으로 당대 예서 창작에 대한 예서의 참고 의의를 간략하게 요약하였다. 논술 과정에서 서예를 근거로 관련 문헌을 탐독하고 모유지의 인생 경험을 결합하여 객관적이게 진술하였다.

• Journal of Plant Biotechnology
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• 제50권
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• pp.190-199
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• 2023

Date palm (Phoenix dactylifera L.: Arecaceae) is a dioecious species where only female trees bear fruits. In their natural state, date palms produce dates once a year. However, in Thailand, some trees were observed to produce dates during the off-season, despite no variations in morphology. The availability of such off-season fruits can significantly increase their market value. Interestingly, most female off-season date palms investigated in this study were obtained through micropropagation. Hence, there is an urgent need for genetic markers to distinguish female offseason flowering plantlets within tissue culture systems. In this study, we aimed to develop random amplification of polymorphic DNA-sequence characterized amplified region (RAPD-SCAR) markers for the identification of female off-season flowering date palms cultivated in Thailand. A total of 160 random decamer primers were employed to screen for specific RAPD markers in off-season flowering male and female populations. Out of these, only one primer, OPN-02, generated distinct genomic DNA patterns in female off-season flowering (FOFdp) individuals compared to female seasonal flowering genotypes. Based on the RAPD-specific sequence, specific SCAR primers denoted as FOFdpF and FOFdpR were developed. These SCAR primers amplified a single 517-bp DNA fragment, predominantly found in off-season flowering populations, with an accuracy rate of 60%. These findings underscore the potential of SCAR marker technology for tracking offseason flowering in date palms. Notably, a BLAST analysis revealed a substantial similarity between the SCAR marker sequence and the transcript variant mRNA from Phoenix dactylifera encoding the SET DOMAIN GROUP 40 protein. In Arabidopsis, this protein is involved in the epigenetic regulation of flowering time. The genetic potential of the off-season flowering traits warrants further elucidation.