• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3691-3698
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• 2014

Background: Published studies on the association between the Ras Association Domain Family 1 isoform A (RASSF1A) Ala133Ser polymorphism and cancer susceptibility have yielded conflicting results. Thus, a meta-analysis was here performed to assess the possible association. Materials and Methods: All eligible case-control studies published up to November 2013 on the association between RASSF1A Ala133Ser polymorphism and cancer susceptibility were identified by searching PubMed, Web of Science, Science Direct and hand search. Bothfixed-effect and random-effect models were used to calculate pooled odds ratios (ORs) with 95% confidence intervals (CIs) by using the Comprehensive Meta-Analysis software version 2.2. Results: A total of 10 studies including 4,572 cancer cases and 4,320 controls were included in the meta-analysis. Overall, significantly increased cancer risk was associated with the variant Ser133 when all studies were pooled (Ser vs Ala: OR=1.51, 95% CI=1.08-2.12, $P_{heterogeneity}{\leq}0.001$; Ser/Ser+Ala/Ser vs Ala/Ala: OR=1.55, 95% CI=1.08-2.22, $P_{heterogeneity}{\leq}0.001$). Moreover, in subgroup analyses by cancer types, a significant association between RASSF1A Ala133Ser polymorphism and lung cancer risk was found (Ser vs Ala: OR=2.27, 95% CI=1.29-4.02, $P_{heterogeneity}$=0.61; Ser/Ser+Ala/Ser vs Ala/Ala: OR=2.42, 95% CI=1.33-4.42, $P_{heterogeneity}=0.75$). In addition, in subgroup analyses by ethnicity, it was found that the RASSF1A Ala133Ser polymorphism was associated with overall cancer risk in Asians (Ser vs Ala: OR=1.37, 95% CI=1.06-1.77, $P_{heterogeneity}=0.06$) and Caucasians (Ser/Ser+Ala/Ser vs Ala/Ala: OR=2.21, 95% CI=1.01-4.82, $P_{heterogeneity}{\leq}0.001$). Conclusions: This meta-analysis suggests, for the first time, that RASSF1A Ala133Ser polymorphism may contribute to cancer susceptibility, especially for lung cancer. Besides, additional well-designed studies with larger sample size focusing on different ethnicities and cancer types are needed to confirm these findings.

• Journal of the Institute of Convergence Signal Processing
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• v.8 no.3
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• pp.143-148
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• 2007

The many studies have been proceeding to express accurately the feature of a sudden signal and a uncertain system in the image processing field. It is well know that Fourier Transform is widely used for frequency analysis of any signal. However, The frequency transform domain is not used for expressing the sudden signal change and non-stationary signal at the time-axis by this method. This paper describes of image analysis by discrete wavelet transform. Wavelet modulus maxima on transformed plane gives the Lipschitz exponent expression, which is useful to examine the characteristics of signal or the edge of an image. It is possible to reconstruct the original image only using the few maxima points. The fractal analysis is applied as an examples. The visualized image of oil flow on a ship model is analyzed. The fractal variable is obtained by the maxima analysis and the good results on the exprement is obtained by the visualized image analysis.

• The Journal of the Korea Contents Association
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• v.12 no.11
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• pp.511-518
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• 2012

In this study, the trend in green technology was observed and the domain of the green technology area that will be actively studied in the future was found by establishing knowledge map in green technology area and comparing and analyzing green technology information in Korea and overseas in time series. For the purpose of this study, network analysis was conducted for the keyword of green technology information provided by green technology information portal site (www.gtnet.go.kr) operated by Korea Institute of Science and Technology Information. Network analysis was conducted using keyword, and change of study subject was found by dividing the analysis result into periods. In the result of network analysis on top 100 keywords from total English keyword, it was found that renewable energy related areas such as solar energy and biomass had high centrality. When the main keyword trend by year was studied, centrality of solar cell, nanotechnology, smart grid, and fuel cell were found to increase, showing that research and development in generation and use of renewable energy are actively made.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.151-157
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• 2019

Recently, monitoring respiration of people has been of interest using non-invasive method. Among the vital signals usually used for indicating health status, non-invasive and portable device based monitoring respiratory status is practically useful and enable one to promptly deal with abnormal physical status. This paper proposes the approach to real-time detection of apnea signal based on Short-Time-Fourier-Transform(STFT). Contrary to the analysis of a signal in frequency domain using Fast-Fourier Transform, this paper employs Short-time-Fourier-Transform so that frequency response can be analyzed in short time interval. The respiratory signal is acquired using UWB radar sensor that enables one to obtain respiration signal in contactless way. Detection of respiratory status is carried out by analyzing frequency response, and classification of respiratory status can be provided. In particular, STFT is employed to analyze respiratory signal in real-time, leading to effective analysis of the respiratory status in practice. In the case of existence of noise in the signal, appropriate filtering process is employed as well. The proposed method is straightforward and is workable in practice to analyze the respiratory status of people. To evaluate the proposed method, experimental results are provided.

• Journal of Korea Soil Environment Society
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• v.4 no.1
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• pp.109-118
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• 1999

Recently, transport parameters of conservative solutes such as KCl in a porous medium have been successfully determined using time domain reflectometry (TDR) . This study was initiated to Investigate the applicability of TDR technique to monitoring the fate of a heavy metal ion in a sandy soil and the distribution of its concentration along travel distance with time. A column test was conducted in a laboratory that consists of monitoring both resident and flux concentrations of $ZnCl_2$in a sandy soil under a breakthrough condition. A tracer of $ZnCl_2$(10 g/L) was injected onto the top surface of the sample as pulse type as soon as a steady-state condition was achieved. Time-series measurements of resistance and electrical conductivity were performed at 10 cm and 20 cm of distances from the inlet boundary by horizontal-positioning of parallel TDR metallic rods and using an EC-meter for the effluent exiting the bottom boundary respectively. In addition. Zn ions of the effluent were analyzed by ICP-AES. Since the mode and position of concentration detected by TDR and effluent were different, comparison between ICP analysis and TDR-detected concentration was made by predicting flux concentration using CDE model accommodating a decay constant with the transport parameters obtained from the resident concentrations. The experimental results showed that the resident concentration resulted in earlier and higher peak than the flux concentration obtained by EC-meter, implying the homogeneity of the packed sandy soil. A close agreement was found between the predicted from the transport parameters obtained by TDR and the measured $ZnCl_2$concentration. This indicates that TDR technique can also be applied to monitoring heavy metal concentrations in the soil once that a decay constant is obtained for a given soil.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.6 s.52
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• pp.1-8
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• 2006

This paper describes the procedures developing the algorithm for analyzing signals acquired from the Bridge Weigh-in-Motion (BWIM) system installed in Seohae Bridge as a part of the bridge monitoring system. Through the analysis procedure, information about heavy traffics such as weight, speed, and number of axles are attempted to be extracted from time domain strain data of the BWIM system. One of numerous pattern recognition techniques, artificial neural network (ANN) is employed since it can effectively include dynamic effects, bridge-vehicle interaction, etc. A number of vehicle running experiments with sufficient load cases are executed to acquire training and/or test set of ANN. Extracted traffic information can be utilized for developing quantitative database of loading effect. Also, it can contribute to estimate fatigue lift or current health condition, and design truck can be revised based on the database reflecting recent trend of traffic.

• Journal of the Society of Naval Architects of Korea
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• v.54 no.3
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• pp.227-241
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• 2017

In this study, a Volterra system for the variations of metacentric height (GM) in waves is employed to simulate the parametric roll phenomena of ships in head sea condition. Using the present Volterra system, the transfer function of each harmonic component in the GM variation is computed for different ship models, including mathematical models and a real containership, and the results are validated through the comparison with the values obtained using the direct calculations based on a weakly nonlinear time-domain method. Then, a semi-analytic approach employing a 1-degree of freedom equation for roll motion is developed to simulate the parametric roll motions in irregular waves. In the derived approach, the nonlinear and time-varying restoring forces in the waves are approximated using the Volterra system. Through simulations of the parametric roll for different sea states, the effects of the 1st and 2nd-order harmonic components of the variations in the occurrence and amplitude of the parametric roll motions are investigated. Because of the strong nonlinearities in the phenomena, a stochastic analysis is conducted to examine the statistical properties of the roll motions in consideration of the sensitivities and uncertainties in the computations.

• Journal of Korea Water Resources Association
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• v.50 no.4
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• pp.233-239
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• 2017

In this study, we analyzed typhoon affecting Korean Peninsula and runoff characteristic changes according to the typhoon based on Sumjin river dam, a representative multi-purpose dam. We quantified typhoon flow by applying the typhoon domain, and will provide base data for climate change adaptation and counterstrategy through correlation analysis of the change of typhoon statistical data and Indicators of Hydrologic Alterations (IHA). Korean Peninsula impact typhoon has a great effect on the scale of peak flow and the change of occurrence time. The occurrence frequency and duration of the peak flow were analyzed to be relatively unrelated to the typhoon affected by the Korean peninsula. These changes were also confirmed in the correlation analysis results. Correlation coefficient between the peak flow (0.41) and peak flow occurrence time (correlation coefficient = 0.83) was positively correlated with the Korean peninsula influenced typhoon.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.5
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• pp.1084-1094
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• 1993

An efficient method for determining forced responses of a general linear structural system in time domain using subtructure modes and Lagrange multipliers is presented. Compared with the conventional mode synthesis methods, the suggested method does not construct the equations of motion of the combined whole structure and thus the modal parameters of the whole structure are not required. Only modal parameters of each substructure and geometric compatibility conditions are needed. Both the loaded interface free-free modes and free interface modes can be employed as the modal bases of each substructure. Recurrence discrete-time state equations based upon state transition matrix are formulated for the transient analysis of a parameter-changing system. It is shown form numerical examples that the suggested method is very accurate and efficient to calculate transient responses compares with the direct numerical integration method.

• Journal of Advanced Marine Engineering and Technology
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• v.36 no.2
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• pp.258-266
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• 2012

Recently, Acoustic Emission (AE) technique is widely applied to develop the early fault detection system, and the problem about a signal processing method for AE signal is mainly focused on. In the signal processing method, envelope analysis is a useful method to evaluate the rolling element bearing problems and Wavelet transform is a powerful method to detect faults occurred on gearboxes. However, exact method for AE signal is not developed yet. Therefore, in this paper, two methods, which is Hilbert transforms (HT) and Hilbert-Huang transforms (HHT), will be compared for development a signal processing method for early fault detection system by using AE. AE signals were measured through a fatigue test. HHT has better advantages than HT because HHT can show the time-frequency domain result. But, HHT needs long time to process a signal, which has a lot of data, and has a disadvantage in de-noising filter.