• Journal of Korean Biological Nursing Science
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• v.13 no.3
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• pp.211-219
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• 2011

Purpose: The study compared the rest-activity rhythm and sleep pattern of elderly with young group. Methods: The subjects were 22 over than 65 years old and 23 under 65 years old. An actigraph, sleep diary, Pittsburgh Sleep Quality Index and Insomnia Severity Index scale were used as measurement tools for this study. The data were analyzed with $x^2$, Lamda test, t-test and correlation with SPSS 15.0 program. Results: The elderly had lower curve than the young group in rest-activity rhythm on each time zone. In particular, the elderly group had lower rest-activity rhythm curve of 8, 9, 14, 18, 19, 20, 21, 22 and 23 time zone than those of young group. Sleep pattern had statistical difference in the total sleep time, PSQI and insomnia. Total sleep time of elderly had lower score and PSQI and Insomnia had higher score than young group. Age had correlation with rest-activity rhythm, sleep efficiency, PSQI and insomnia. Conclusion: Rest-activity rhythm of the elderly showed an increase in activity in the early morning because of earlier get up than the young group and an decrease in activity in the afternoon because of taking a nap at this time. Elderly sleep was that total sleep time increased but sleep efficiency decreased and insomnia intensified. This sleep pattern was related to age and rest-activity rhythm.

• Microbiology and Biotechnology Letters
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• v.37 no.1
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• pp.80-84
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• 2009

The in vitro antibacterial activities of anti-acne agents prepared from the extracts of natural sources were investigated against several bacteria including antibiotic-susceptible and -resistant Propionibacterium acnes. SD-1 and SD-2 were prepared with different formulations and they showed strong antibacterial activities. The anti-acne agents completely inhibited the growth of the tested strains at the concentration of 0.5%. There was no difference in antibacterial activity between antibiotic-susceptible and -resistant P. acnes. The inhibitory activities of two agents showed time-dependent manner. In S. aureus, time-kill curve demonstrated 2.8- and 3.4-$log_{10}$-unit killing after 8 h with SD-1 and SD-2, respectively. In P. acnes, time-killing curve demonstrated 5.1- and 6.1-$log_{10}$-unit killing after 24 h with SD-1 and SD-2, respectively. SD-2 showed stronger antimicrobial activity than SD-1. From these results, we expect that SD-1 and SD-2 have strong antibacterial activities and have advantages for treating acne.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2021.05a
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• pp.203-204
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• 2021

Bacteria used in self-healing concrete, which arrest the crack, helps increasing the durability is well known. However, the survival and activity of the bacteria are precisely unknown. In this research, to know the bacteria's survival curve on the surface of the cement composite, bacteria's survival curve has been measured by CFU at different curing days. The survival curve of 3 days and 7 days curing does not show the significant differences in their survival tendency. However, the slope of death phase of 7 days curing was steeper than the 3 days of curing. This research was focused on the death phase but for further research, set of interval time will be reduced and observe the lag phase and exponential phase.

• Journal of radiological science and technology
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• v.29 no.4
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• pp.249-255
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• 2006

Purpose: The diagnostic utility of fluorine-18 2-deoxy-D-glucose positron emission tomograhpy ($^{18}F-FDG $PET) for the non-invasive differentiation of focal lung lesions originated from cancer or inflammation disease by combined visual image interpretation and semi-quantitative uptake value analysis has been documented. In general, Standardized Uptake Value(SUV) is used to diagnose lung disease. But SUV does not contain dynamic information of lung tissue for the glucose. Therefore, this study was undertaken to hypothesis that analysis of dynamic kinetics of focal lung lesions base on $^{18}F-FDG$ PET may more accurately determine the lung disease. So we compared Time Activity Curve(TAC), Standardized Uptake Value-Dynamic Curve(SUV-DC) graph pattern with Glucose Metabolic Rate(MRGlu) from Patlak analysis. Methods: With lung disease, 17 patients were examined. They were injected with $^{18}F-FDG$ over 30-s into peripheral vein while acquisition of the serial transaxial tomographic images were started. For acquisition protocol, we used twelve 10-s, four 30-s, sixteen 60-s, five 300-s and one 900-s frame for 60 mins. Its images were analyzed by visual interpretation TAC, SUV-DC and a kinetic analysis(Patlak analysis). The latter was based on region of interest(ROIs) which were drawn with the lung disease shape. Each optimized patterns were compared with itself. Results: In TAC patterns, it hard to observe cancer type with inflammation disease in early pool blood area but over the time cancer type slope more remarkably increased than inflammation disease. SUV-DC was similar to TAC pattern. In the result of Patlak analysis, In time activity curve of aorta, even though inflammation disease showed higher blood activity than cancer, at first as time went by, blood activity of inflammation disease became the lowest. However, in time activity curve of tissue, cancer had the highest uptake and inflammation disease was in the middle. Conclusion: Through the examination, TAC and SUV-DC could approached the results that lung cancer type and inflammation disease type has it's own difference shape patterns. Also, it has outstanding differentiation between cancer type and inflammation in Patlak and MRGlu analysis. Through these analysis methods, it will helpful to separation lung disease.

• Korean Journal of Veterinary Research
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• v.39 no.2
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• pp.390-393
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• 1999

Transcolonic scintigraphy using $^{99m}Technetium$ pertechnetate ($^{99m}TcO_{4}$) was performed in 5 dogs with portosystemic shunts. In all dogs, the activity in the heart was seen before liver activity. Also time activity curve was revered. The mean shunt index in 5 dogs was 82.3% (range 79.6~87.1%). Transcolonic scintigraphy is quick, simple and useful diagnostic method for canine portosysternic shunts.

• YAKHAK HOEJI
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• v.47 no.6
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• pp.365-368
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• 2003

The bactericidal activities of DW286, a new fluoroquinolone were investigated by comparing the minimal bactericidal concentrations (MBCs) and the time-kill curve of it against some Gram-positive and Gram-negative bacterial strains. The MBCs of DW286 for the strains tested were either equal to or two-fold higher than the MICs, as were observed for the other fluoroquinolones. And DW286 exhibited rapid killing curves against the strains. Accordingly, it could be said that DW286 has bactericidal activity comparable to other fluoroquinolones.

• Korean Journal of Materials Research
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• v.12 no.1
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• pp.75-81
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• 2002

The ferroelectric properties of Pb(Zr,Ti)O$_3$[PZT] films degrade when the films with Pt top electrodes are annealed in hydrogen containing environment. This is due to the reduction activity of atomic hydrogen that is generated by the catalytic activity of the Pt top electrode. At the initial stage of hydrogen annealing, oxygen vacancies are formed by the reduction activity of hydrogen mainly at the vicinity of top Pt/PZT interface, resulting in a shift of P-E (polarization-electric field) hysteresis curve toward the negative electric field direction. As the hydrogen annealing time increases, oxygen vacancies are formed inside the PZT film by the inward diffusion of hydrogen ions, as a result, the polarization degrades significantly and the degree of P-E curve shift decreases gradually. The direction and the magnitude of the remnant polarization in the PZT film affect the motion of hydrogen ions which determines the degradation of polarization characteristics and the shift in the P-E hysteresis curve of the PZT capacitor during hydrogen annealing. When the remnant polarization is formed in the PZT film by applying a pre-poling voltage prior to hydrogen annealing, the direction of the P-E curve shift induced by hydrogen annealing is opposite to the polarity of the pre-poling voltage. The hydrogen-induced degradation behavior of the PZT capacitor is also affected by the internal field that has been generated in the PZT film by the charges located at the top interface prior to hydrogen annealing.

• Journal of the Korean Society of Radiology
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• v.9 no.6
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• pp.357-362
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• 2015

This study was to evaluate the usefulness through the comparison of patients group and healthy control group by acquiring a variety of functional parameters index from time-activity curves of salivary gland scan using 99mTc-pertechnetate. From December 2014 to February 2015, had the targets of 30 patients with dry mouth and 10 people in healthy control group underwent the salivary gland scan. After intravenous injection of 370 MBq of 99mTc-pertechnetate, Vitamin C powder stimulation was administerd orally at 20 min and then 10 minutes were taken scan. The method of quantitative analysis was as follows, the time-activity curve was drawn after the parotid gland and submandible gland were prescribed as a region of interest, a variety of function parameters index was obtained in each position of the curve, and the patients group and the control group were compared. As for the methods applied in comparison and measurement, uptake ratio (UR), time at maximum counts (Tmax), time at minimum counts (Tmin), maximum accumulation (MA), accumulation velocity, maximum secretion (MS), maximum stimulation secretion (MSS), and secretion velocity (SV) were used. In the comparison of functional parameters index of patient group and normal group, the healthy normal group showed significant difference compared to the patient group in all indices except for the minimum radioactivity time (Tmin), and also in terms of variation over time the normal group showed significant difference compared to the patient group (p<0.05). Consequently, it was considered that the quantitative analysis that used a variety of function parameters index would be useful for evaluating the function of the salivary glands of the patients with dry mouth as an objective and standardized information.

• Journal of the Korean Society of Child Welfare
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• no.56
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• pp.101-132
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• 2016

Fandom is a meaningful social phenomenon that represents a significant dimension of contemporary Korean youth culture. Previous research, however, has considered fandom as a deviant activity that is negative in nature, and there is scant research on the positive effects of fandom activity. This study examined the effects of off-line and on-line fandom activity participation on adolescents' academic time management capability. Data were collected from three waves (2010, 2012, and 2014) of the Korean Children and Youth Panel Survey (middle school cohort; N=2,206 at baseline). Results from the multi-level growth curve analysis were as follows. First, more than half of the adolescents reported participating in fandom activities, and the majority of them participated in both online and offline activities. Second, adolescents' academic time management capability improved over time. Third, both off-line and on-line fandom activity participation was positively associated with adolescents' academic time management capability at the baseline (first year of middle school). The size of this relationship, however, decreased over time (from middle school to high school). This study presented the importance of appropriate guidance by adults to develop and promote the positive aspects of fandom activity, and highlighted the need for further research that focuses on the positive aspects of fandom activities.

• Journal of the East Asian Society of Dietary Life
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• v.12 no.3
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• pp.241-248
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• 2002

The dried Prunus mume, an alkaline food abundant in organic acids (citric acid, malic acid and tartaric acid), has been largely used in both folklore remedies and Chinese herbal medicine for a long time. This study was performed to investigate the antimicrobial activity of the dried Prunus mume. The fractionation of the methanol extracts from Prunus mume was conducted using petroleum ether, chloroform, ethyl acetate and butanol, respectively. The antimicrobial activity of the Prunus mume extracts was then determined against food-borne pathogens using a paper disc method. The ethyl acetate extract showed the strongest antimicrobial activity against the eigth food-born pathogens used in this present study. Diaion HP 20 column chromatography was performed to remove some sugars that might inhibit the antimicrobial activity of Prunus mume. The strongest antimicrobial activity of ethyl acetate fraction of Prunus mume was shown against Staphylococus aureus. The growth inhibition curve was determined using ethyl acetate extracts of Prunus mume against Staphylococus aureus, which showed the growth inhibition up to 72 hours at 1,000 ppm concentration.