YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Bactericidal Activity of DW286, a New Fluoroquinolone Antibiotic

새로운 퀴놀론 항균제 Dw286의 살균작용

  • 윤희정 (서울대학교 약학대학· 종합약학연구소) ;
  • 민유홍 (서울대학교 약학대학· 종합약학연구소) ;
  • 심미자 (서울시립대학교 생명과학과) ;
  • 최응칠 (서울대학교 약학대학· 종합약학연구소)
  • Published : 2003.12.01
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Abstract

The bactericidal activities of DW286, a new fluoroquinolone were investigated by comparing the minimal bactericidal concentrations (MBCs) and the time-kill curve of it against some Gram-positive and Gram-negative bacterial strains. The MBCs of DW286 for the strains tested were either equal to or two-fold higher than the MICs, as were observed for the other fluoroquinolones. And DW286 exhibited rapid killing curves against the strains. Accordingly, it could be said that DW286 has bactericidal activity comparable to other fluoroquinolones.

Keywords

References

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