• Title/Summary/Keyword: Threshold concentration

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Projecting future hydrological and ecological droughts with the climate and land use scenarios over the Korean peninsula (기후 및 토지이용 변화 시나리오 기반 한반도 미래 수문학적 및 생태학적 가뭄 전망)

  • Lee, Jaehyeong;Kim, Yeonjoo;Chae, Yeora
    • Journal of Korea Water Resources Association
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    • v.53 no.6
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    • pp.427-436
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    • 2020
  • It is uncertain how global climate change will influence future drought characteristics over the Korean peninsula. This study aims to project the future droughts using climate change and land use change scenarios over the Korean peninsula with the land surface modeling system, i.e., Weather Research and Forecasting Model Hydrological modeling system (WRF-Hydro). The Representative Concentration Pathways (RCPs) 2.6 and 8.5 are used as future climate scenarios and the Shared Socio-economic Pathways (SSPs), specifically SSP2, is adopted for the land use scenario. The using Threshold Level Method (TLM), we identify future hydrological and ecological drought events with runoff and Net Primary Productivity (NPP), respectively, and assess drought characteristics of durations and intensities in different scenarios. Results show that the duration of drought is longer over RCP2.6-SSP2 for near future (2031-2050) and RCP8.5-SSP2 (2080-2099) for the far future for hydrological drought. On the other hand, RCP2.6-SSP2 for the far future and RCP8.5-SSP2 for the near future show longer duration for ecological drought. In addition, the drought intensities in both hydrological and ecological drought show different characteristics with the drought duration. The intensity of the hydrological droughts was greatly affected by threshold level methods and RCP2.6-SSP2 for far future shows the severest intensity. However, for ecological drought, the difference of the intensity among the threshold level is not significant and RCP2.6-SSP2 for near future and RCP2.6-SSP2 for near future show the severest intensity. This study suggests a possible future drought characteristics is in the Korea peninsula using combined climate and land use changes, which will help the community to understand and manage the future drought risks.

A New Selection System for Pepper Regeneration by Mannose

  • Kim, Joo-Yean;Min Jung;Kim, Hyo-Soon;Lee, Yun-Hee;Park, Soon-Ho;Lim, Yong-Pyo;Min, Byung-Whan;Yang, Seung-Gyun;Harn, Chee-Hark
    • Journal of Plant Biotechnology
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    • v.4 no.3
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    • pp.129-134
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    • 2002
  • We report the development of a new selection system for the transformation of pepper plants by mannose. In order to achieve this, we first tested several factors related to regeneration conditions. Among the 30 inbred lines examined, line P9l5 was able to generate shoots at the highest rate from both cotyledons and hyporotyls in MS media. A dosage curve for optimizing the selection conditions was established by mixing mannose (range 0-50 g/L) and sucrose (range 0-30 g/L). The least selection pressure on shoot formation was created by a mixture of sucrose and mannose at 20 g/L and 15 g/L, respectively, and the threshold for ultimate tissue death was 50 g/L of mannose irrespective of the sucrose concentration. However, we found that mannose itself was not the sole inhibitor of pepper shoot development. High concentrations of sucrose (30 g/L) contributed additively to the inhibition of shoot formation at higher mannose concentrations. Genotype preference is a major factor that enhances regeneration ability in mannose media, as was observed in MS media. P9l5 and P410 line had high regeneration rates under mannose selection conditions in the presence of Agrobacterium infection. Different virulence levels of Agrobacterium strains did change the regeneration rates, probably due to interaction with the specificities of the inbred lines. Taken together, P9l5 offers the best pepper inbred line for transformation and we recommend a selection condition of 20 g/L of sucrose and 15 g/L or more of mannose up to 50 g/L in media.

Prediction of Chloride Profile considering Binding of Chlorides in Cement Matrix

  • Song, Ha-Won;Lee, Chang-Hong;Ann, Ki Yong
    • Corrosion Science and Technology
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    • v.8 no.2
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    • pp.81-88
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    • 2009
  • Chloride induced corrosion of steel reinforcement inside concrete is a major concern for concrete structures exposed to a marine environment. It is well known that transport of chloride ions in concrete occurs mainly through ionic/molecular diffusion, as a gradient of chloride concentration in the concrete pore solution is set. In the process of chloride transport, a portion of chlorides are bound in cement matrix then to be removed in the pore solution, and thus only the rest of chlorides which are not bound (i.e. free chlorides) leads the ingress of chlorides. However, since the measurement of free/bound chloride content is much susceptible to environmental conditions, chloride profiles expressed in total chlorides are evaluated to use in many studies In this study, the capacity of chloride binding in cement matrix was monitored for 150 days and then quantified using the Langmuir isotherm to determine the portions of free chlorides and bound chlorides at given total chlorides and the redistribution of free chlorides. Then, the diffusion of chloride ion in concrete was modeled by considering the binding capacity for the prediction of chloride profiles with the redistribution. The predicted chloride profiles were compared to those obtained from conventional model. It was found that the prediction of chloride profiles obtained by the model has shown slower diffusion than those by the conventional ones. This reflects that the prediction by total chloride may overestimate the ingress of chlorides by neglecting the redistribution of free chlorides caused by the binding capacity of cement matrix. From the evaluation, it is also shown that the service life prediction using the free chloride redistribution model needs different expression for the chloride threshold level which is expressed by the total chlorides in the conventional diffusion model.

Fatigue Life Evaluation of Butt-Welded Tubular Joints

  • Kim, Dong-Su;Nho, In-Sik
    • Journal of Ocean Engineering and Technology
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    • v.17 no.2
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    • pp.34-39
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    • 2003
  • Recent deepwater offshore structures in the Gulf of Mexico utilize butt welded tubular joints. Application of a welded tubular joint includes tendons, production risers, and steel catenary risers. Fatigue life assessment of these joints becomes more critical, as the structures to which they are attached are allowed to undergo cyclic and sometimes large displacements around an anchored position. Estimation of the fatigue behavior of these tubular members in the design stage is generally condrcted by using S-N curves, as specified in the codeds and standards. Applying the stress concentration factor of the welded structure to the S-N approach often results in a very conservative assessment, because the stress field acting on the tubular has a non-uniform distribution through the thickness. Fatigue life analysis using fracture mechanics has been applied in the design of the catenary risers. This technology enables the engineer to establish proper requirements on weld quality and inspection acceptance criteria to assure satisfactory structural integrity during its design life. It also provides guidance on proper design curves and a methodology for accounting for the effects of non-uniform stress distribution through the wall thickness. Still, there is inconsistency when designing tubular joints using a conventional S-N approach and when specifying weld flaw acceptance criteria using fracture mechanics approach. This study developed fatigue curves that are consistent with both the S-N approach and the fracture mechanics approach. Accounting for non-uniform stress distribution and threshold stress intensity factor were key parameters in relating both approaches. A series of S-N curves, generated from the fracture mechanics approach, were compared to the existing S-N curves. For flat plate butt joint, the S-N curve generated from fracture mechanics matches with the IIW class 100 curve when initial crack depth was 0.5 mm (0.02 ). The new curves for tubular joint agree very well with the experimental results. The comparison also indicated the degree of conservatism built into the API X design curve.

Relationship between Workers′ Exposure to Airborne Chromium and Blood and Urine Chromium Levels in Plating Process (도금업체 근로자의 공기중 크롬 노출 농도와 요 및 혈중 크롬 농도간의 상관성)

  • 이지태;신용철
    • Journal of Environmental Health Sciences
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    • v.27 no.3
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    • pp.1-10
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    • 2001
  • This study was performed to evaluate chromium in air and chromium concentrations in whole blood and urine of workers at chrome plating factories, and to determine the correlation between environmental and biological chromium levels. This study involved 29 workers as study group and 24 undergraduate students as control group. The geometric means(GM) of airborne hexavalent chromium and total chromium concentrations in the plating factories were 3.4 $\mu\textrm{g}$/㎥ and 10.8 $\mu\textrm{g}$/㎥, respectively. Hexavalent chromium levels in two of total 29 measurements exceeded the korean occupational exposure limit and the American Conference of Governmental Industrial Hygienists Threshold Limit Value(ACGIH-TLV) of 50$\mu\textrm{g}$/㎥. Only one sample for total chromium exceeded the Korea occupational exposure limits, the ACGIH-TLV, and the National Institute for Occupational Safety and Health Recommended Exposure Limits(NIOSH-REL) of 500 $\mu\textrm{g}$/㎥. The GM of chromium concentrations in blood and urine of workers exposed to chromium were 8.4 $\mu\textrm{g}$/L and 11.9 $\mu\textrm{g}$/L. The GM of chromium concentrations in blood and urine of workers exposed to chromium were 8.4 $\mu\textrm{g}$/L and 11.9 $\mu\textrm{g}$/L, respectively, whereas the chromium concentrations in blood and urine of the controls were 1.6 $\mu\textrm{g}$/L and 3.8 $\mu\textrm{g}$/L, respectively. There were statistically significant differences of blood and urine concentrations between study group and control group (p<0.01). The chromium concentrations in urine were most highly related to hexavalent chromium, concentration in air(r=0.642, p<0.01). Also, there was a relatively high correlation between the hexavalent chromium concentrations in air and chromium concentrations in whole blood(r=0.557, p<0.05). These results indicate that whole-blood chromium with urinary chromium could be an indicator of chromium body burden caused by exposure to chromic acid mist in plating operation.

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Apply AEGL for Short Time Exposure Using Regression Curve (회귀곡선을 이용한 단시간 노출에 대한 AEGL의 적용)

  • Lee, Hyunjin;Jeong, Taejun;Lee, Hyang-Jig;Jeong, Changmo;Ko, Jae-Wook
    • Journal of the Korean Institute of Gas
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    • v.21 no.5
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    • pp.77-82
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    • 2017
  • Thus, chemicals are managed under 9 related central government department and 16 relevant laws with program such as Process Safety Management and Offsite Consequence Analysis in korea. Guidelines for set the endpoint concentration for chemcals based on the ERPG-2 (Emergency Response Planning Guidelines-2) and AEGL-2 (Acute Exposure Guidelines Level-2). but ERPG and AEGL do not describe exposure for less than 10 minutes. because of this, each guidelines define criteria differently for short time less than 10 minutes exposure. This indefinite exposure criteria would give rise to a confusion in the chemical plants, and potentially lead to a critical decision making error when accidents happen. In an effort to apply guidelines with evenly-distributed initial time frame, AEGL concentrations within 10 minute exposure time were evaluated by examining statistical regression curves. The results were in good agreement with those from the Probit Function based on each AEGL grade to explain 3 different threshold levels of exposure effects. Resultant re-enforced guidelines for endpoint chemical concentrations are, therefore, to provide powerful tool to assess and manage the risk associated with any potential chemical accidents at an early stage.

A Study on Breakthrough of Respirator Cartridge Using Multi-Organic Vapor Mixtures (복합유기용제에 노출된 호흡보호구용 정화통의 파과에 관한 연구)

  • Chung, Hai-Dong;Paik, Nam Won
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.6 no.1
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    • pp.55-66
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    • 1996
  • This study was conducted to evaluate breakthrough characteristics of respirator cartridge using multi-organic vapors, including carbon tetrachloride, trichloroethylene, and toluene. The organic vapors were used as single phase, binary system, and ternary system. The results are summarized as follows. 1. Organic vapors studied were 1,000 ppm, 750 ppm, 500 ppm and 250 ppm in single phase. Carbon tetrachloride having the highest molecular weight showed the breakthrough first, and breakthrough sequency by organic vapor was dependent on its molecular weight. The 10% breakthrough times at 1,000 ppm of organic vapor were 97 minutes for carbon tetrachloride, 129 minutes for trichloroethylene and 135 minutes for toluene. 2. When concentrations of organic vapors were at levels of the Threshold Limit Values, the lives of the respirator cartridges were 122 hours in carbon tetrachloride, 18 hours in trichloroethylene and 28 hours in toluene. 3. In the binary system at a total concentration of 1,000 ppm with carbon tetrachloride and trichloroethylene, breakthrough times ranged from 104 minutes to 125 minutes, which were longer than 97 minutes in a single phase (1,000 ppm) for carbon tetrachloride, but shorter than breakthrough times for TCE and Toluene. 4. Breakthrough times in the binary system with carbon tetrachloride and toluene were 131~132 minutes. 5. Breakthrough times in the ternary system with carbon tetrachloride, toluene, and trichloroethyl ene were $120{\pm}8$ minutes, which were longer than 97 minutes in the single phase (1,000 ppm) for carbon tetrachloride, equal to 129 minutes for trichloroethylene, and shorter than 135 minutes for toluene. Those were almost similar to $124{\pm}9$ minutes of breakthrough times in the binary systems.

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Risk Assessment of Baby Powder Exposure through Inhalation

  • Moon, Min-Chaul;Park, Jung-Duck;Choi, Byung-Soon;Park, So-Young;Kim, Dong-Won;Chung, Yong-Hyun;Hisanaga, Naomi;Yu, Il-Je
    • Toxicological Research
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    • v.27 no.3
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    • pp.137-141
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    • 2011
  • This study was conducted to assess the exposure risk through inhalation to baby powder for babies and adults under simulated conditions. Baby powder was applied to a baby doll and the amount of baby powder consumed per application was estimated. The airborne exposure to baby powder during application was then evaluated by sampling the airborne baby powder near the breathing zones of both the baby doll and the person applying the powder (the applicator). The average amount of baby powder consumed was 100 mg/application, and the average exposure concentration of airborne baby powder for the applicator and baby doll was 0.00527 mg/$m^3$ (range 0.00157~0.01579 mg/$m^3$) and 0.02207 mg/$m^3$ (range 0.00780~0.04173 mg/$m^3$), respectively. When compared with the Occupational Exposure Limit of 2 mg/$m^3$ set by the Korean Ministry of Labor and the Threshold Limit Value (TLV) of 2 mg/$m^3$ set by the ACGIH (American Conference of Governmental Industrial Hygienists), the exposure concentrations were much lower. Next, the exposure to asbestos-containing baby powder was estimated and the exposure risk was assessed based on the lung asbestos contents in normal humans. As a result, the estimated lung asbestos content resulting from exposure to asbestos-containing baby powder was found to be much lower than that of a normal Korean with no asbestos-related occupational history.

Effect of carbamazepine on tetrodotoxin-resistant Na+ channels in trigeminal ganglion neurons innervating to the dura

  • Han, Jin-Eon;Cho, Jin-Hwa;Nakamura, Michiko;Lee, Maan-Gee;Jang, Il-Sung
    • The Korean Journal of Physiology and Pharmacology
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    • v.22 no.6
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    • pp.649-660
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    • 2018
  • Migraine is a neurological disorder characterized by recurrent and disabling severe headaches. Although several anticonvulsant drugs that block voltagedependent $Na^+$ channels are widely used for migraine, far less is known about the therapeutic actions of carbamazepine on migraine. In the present study, therefore, we characterized the effects of carbamazepine on tetrodotoxin-resistant (TTX-R) $Na^+$ channels in acutely isolated rat dural afferent neurons, which were identified by the fluorescent dye DiI. The TTX-R $Na^+$ currents were measured in medium-sized DiIpositive neurons using the whole-cell patch clamp technique in the voltage-clamp mode. While carbamazepine had little effect on the peak amplitude of transient $Na^+$ currents, it strongly inhibited steady-state currents of transient as well as persistent $Na^+$ currents in a concentration-dependent manner. Carbamazepine had only minor effects on the voltage-activation relationship, the voltage-inactivation relationship, and the use-dependent inhibition of TTX-R $Na^+$ channels. However, carbamazepine changed the inactivation kinetics of TTX-R $Na^+$ channels, significantly accelerating the development of inactivation and delaying the recovery from inactivation. In the current-clamp mode, carbamazepine decreased the number of action potentials without changing the action potential threshold. Given that the sensitization of dural afferent neurons by inflammatory mediators triggers acute migraine headaches and that inflammatory mediators potentiate TTX-R $Na^+$ currents, the present results suggest that carbamazepine may be useful for the treatment of migraine headaches.

Relation of Oxide Thickness and DIBL for Asymmetric Double Gate MOSFET (비대칭 이중게이트 MOSFET에서 산화막 두께와 DIBL의 관계)

  • Jung, Hakkee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.4
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    • pp.799-804
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    • 2016
  • To analyze the phenomenon of drain induced barrier lowering(DIBL) for top and bottom gate oxide thickness of asymmetric double gate MOSFET, the deviation of threshold voltage is investigated for drain voltage to have an effect on barrier height. The asymmetric double gate MOSFET has the characteristic to be able to fabricate differently top and bottom gate oxide thickness. DIBL is, therefore, analyzed for the change of top and bottom gate oxide thickness in this study, using the analytical potential distribution derived from Poisson equation. As a results, DIBL is greatly influenced by top and bottom gate oxide thickness. DIBL is linearly decreased in case top and bottom gate oxide thickness become smaller. The relation of channel length and DIBL is nonlinear. Top gate oxide thickness more influenced on DIBL than bottom gate oxide thickness in the case of high doping concentration in channel.