Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Risk Assessment of Baby Powder Exposure through Inhalation

  • Moon, Min-Chaul (Toxicological Research Center, Hoseo University) ;
  • Park, Jung-Duck (Department of Preventive Medicine, Chung-Ang University) ;
  • Choi, Byung-Soon (Occupational Lung Disease Institute, Korea Workers' Compensation & Welfare service) ;
  • Park, So-Young (Occupational Lung Disease Institute, Korea Workers' Compensation & Welfare service) ;
  • Kim, Dong-Won (Department of Preventive Medicine, Chung-Ang University) ;
  • Chung, Yong-Hyun (Center for Occupational Toxicology, Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency) ;
  • Hisanaga, Naomi (Aichi University of Education) ;
  • Yu, Il-Je (Toxicological Research Center, Hoseo University)
  • Received : 2011.03.22
  • Accepted : 2011.05.27
  • Published : 2011.09.01
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Abstract

This study was conducted to assess the exposure risk through inhalation to baby powder for babies and adults under simulated conditions. Baby powder was applied to a baby doll and the amount of baby powder consumed per application was estimated. The airborne exposure to baby powder during application was then evaluated by sampling the airborne baby powder near the breathing zones of both the baby doll and the person applying the powder (the applicator). The average amount of baby powder consumed was 100 mg/application, and the average exposure concentration of airborne baby powder for the applicator and baby doll was 0.00527 mg/$m^3$ (range 0.00157~0.01579 mg/$m^3$) and 0.02207 mg/$m^3$ (range 0.00780~0.04173 mg/$m^3$), respectively. When compared with the Occupational Exposure Limit of 2 mg/$m^3$ set by the Korean Ministry of Labor and the Threshold Limit Value (TLV) of 2 mg/$m^3$ set by the ACGIH (American Conference of Governmental Industrial Hygienists), the exposure concentrations were much lower. Next, the exposure to asbestos-containing baby powder was estimated and the exposure risk was assessed based on the lung asbestos contents in normal humans. As a result, the estimated lung asbestos content resulting from exposure to asbestos-containing baby powder was found to be much lower than that of a normal Korean with no asbestos-related occupational history.

Keywords

References

  1. American Conference of Governmental Industrial Hygienists. (2005). Threshold limit values for chemical substances and physical agents, and biological exposure indices. Cincinatti, OH.
  2. Asgharian, B., Ménache, M.G. and Miller, F.J. (2004). Modeling age-related particle deposition in humans. J. Aerosol Med., 17, 213-224. https://doi.org/10.1089/jam.2004.17.213
  3. Dongailbo, April 1, 2009, http://news.donga.com/3/all/20090401/8714937/1.
  4. Han, J.H., Park, J.D., Sakai, K., Hisanaga, N., Chang, H.K., Lee, Y.H., Kwon, I.H., Choi, B.S., Chung, Y.H., Kim, H.Y., Yang, J.S., Cho, M.H. and Yu, I.J. (2009). Comparison of lung asbestos fiber content in cancer subjects with healthy individuals with no known history of occupational asbestos exposure in Korea. J. Toxicol. Environ. Health A, 72, 1292-1295. https://doi.org/10.1080/15287390903212345
  5. International Agency for Cancer Research (IARC) (2010). IARC monograph on the evaluation of cancer risk to humans, Volume 93. Carbon black, titanium dioxide and talc, IARC, Lyon.
  6. International Labor Organization (ILO). (2006). Resolution Concerning Asbestos. 95th International labor Conference, Report of the Committee on Safety and Health. Geneva: May 31 ?June 16, 2006, available at : http://www.ilo.org/safework/normative/lang--en/WCMS_108556/index.htm, accessed January 9, 2011.
  7. Joongangilbo, April 2, 2009, Available at: http://pdf.joinsmsn.com/article/pdf_article_prv.asp?id=DY01200904020042.
  8. Korea Food and Drug Administration, April 3, 2009a, Available at: http://www.kfda.go.kr/index.kfda?mid=50&seq=3154&cmd=v.
  9. Korea Food and Drug Administration, April 6, 2009b, Available at: http://www.kfda.go.kr/index.kfda?mid=56&seq=1754&cmd=v.
  10. Kuminilbo, April 1, 2009, Available at: http://news.kukinews.com/article/view.asp?page=1&gCode=all&arcid=1238617707&code=14131101.
  11. Mattenklott, M. (2007). Asbest in talkumpudern und speckstein - Heutige situation. Gefahrstoffe Reinhaltung der Luft, 67, 287-292.
  12. Ministry of Employment and Labor (2010). Occupational Safety and Health Act, Notification of Ministry of Labor (2010-44), Exposure limits of Chemical substances and physical agents.
  13. National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention. (2003). NIOSH Manual of Analytical Methods 0500 and 9105. available at: http://www.cdc.gov/niosh/docs/2003-154/pdfs/0500.pdf, accessed January 9, 2011.
  14. Oestenstad, K., Honda, Y., Delzell, E. and Brill, I. (2002). Assessment of historical exposures to talc at a mining and milling facility. Ann. Occup. Hyg., 46, 587-596. https://doi.org/10.1093/annhyg/mef076
  15. Paoletti, L., Caiazza, S., Donelli, G. and Pocchiari, F. (1984). Evaluation by electron microscopy techniques of asbestos contamination in industrial, cosmetic, and pharmaceutical talcs. Regul. Toxicol. Pharmacol., 4, 222-235. https://doi.org/10.1016/0273-2300(84)90022-9
  16. Plog, B.A., Niland, J. and Quinlan, P.J. (1996). Fundamentals of Industrial Hygiene, 4th edition, National Safety Council, Illonios.
  17. Price, B. (2010). Industrial-grade talc exposure and the risk of mesothelioma. Crit. Rev. Toxicol., 40, 513-530. https://doi.org/10.3109/10408441003646781
  18. Sakai, K., Kojima, A., Hisanaga, N., Shibata, E., Huang, J., Ono, Y., Takeuchi, Y., Aoki, T., Takagi, H. and Ando, T. (1991). Asbestos concentrations and fiber size in lungs of the urban residents. Nihon. Koshu. Eisei. Zasshi., 38, 762-770.
  19. Sakai, K., Kojima, A., Hisanaga, N., Shibata, E., Ono, Y., Takeuchi, Y., Aoki, T., Takagi, H., Ando, T. and Huang, J. (1993). Inhaled non-asbestos fibers; Pulmonary concentrations and fiber size in autopsied urban residents. Nihon. Koshu. Eisei. Zasshi., 40, 302-312.
  20. Sakai, K., Hisanaga, N., Huang, J., Shibata, E., Ono, Y., Aoki, T., Takagi, H., Ando, T., Yokoi, T. and Takeuchi. Y. (1994). Asbestos and non-asbestos fiber content in lung tissue of Japanese patients with malignant mesothelioma. Cancer, 73, 1825-1835. https://doi.org/10.1002/1097-0142(19940401)73:7<1825::AID-CNCR2820730709>3.0.CO;2-M
  21. Sakai, K., Hisanaga, N., Okuno, M., Kohyama, N., Shinohara, Y., Shibata, E., Kamijima, M., Yamanaka, K. and Takeuchi, Y. (1996). Concentration and fiber size of asbestos in lungs of residents living close to the serpentinite area. Nihon. Koshu. Eisei. Zasshi., 43, 551-562.
  22. Straif, K., Keil, U., Taeger, D., Holthenrich, D., Sun, Y., Bungers, M. and Weiland, S.K. (2000). Exposure to nitrosamines, carbon black, asbestos, and talc and mortality from stomach, lung, and laryngeal cancer in a cohort of rubber workers. Am. J. Epidemiol., 152, 297-306. https://doi.org/10.1093/aje/152.4.297
  23. Wild, P., Leodolter, K., Refregier, M., Schmidt, H. and Bourgkard, E. (2008). Effects of talc dust on respiratory health: results of a longitudinal survey of 378 French and Austrian talc workers. Occup. Environ. Med., 65, 261-267. https://doi.org/10.1136/oem.2007.034298
  24. World Bank Group. (2009). Good Practice Note: Asbestos: Occupational and Community Health Issues, Available at: http://siteresources.worldbank.org/EXTPOPS/Resources/AsbestosGuidanceNoteFinal.pdf accessed January 21, 2011.
  25. World Federation of Public Health Associations (2005). Call For a Global Ban on the Mining and Use of Asbestos, available at : http://www.wfpha.org/Archives/05_policy_Asbestos.pdf.
  26. Yu, I.J., Moon, Y.H., Sakai, K., Hisanaga, N., Park, J.D. and Takeuchi, Y. (1998) Asbestos and non-asbestos fiber content in lungs of Korean subjects with no known occupational asbestos exposure history. Environment International, 24, 293-300. https://doi.org/10.1016/S0160-4120(98)00008-7

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