The use of fermented soy curd as a functional substance has been actively studied due to the anti-inflammatory and antiallergic activity of soybean protein hydrolyzate by enzymes of lactic acid bacteria. The present study investigated the potential of soy curd as a treatment for atopic dermatitis (AD). Pediococcus inopinatus Y2 (P. inopinatus Y2) lactic acid bacteria were inoculated into soy milk and fermented ($30^{\circ}C$, 24 hr). Changes in body weights, ear thicknesses, IgE concentrations, and weights of immune organs in ICR female mice were quantified. Moderate weight gain occurred in most of the groups. The ear thickness was lowest in the untreated group (no group), and it was allergic and thickened in the phthalic anhydride (PA) treatment group. Based on visual observations, as compared with the skin condition of the PA-induced AD group, the skin condition of the animals in the fermented soy curd (FSC) group was improved. Therefore, FSC by lactic acid bacteria seemed to improve AD. Based on the comparison of the weights of the spleen, thymus, and lymph nodes, as well as the results of the IgE analysis, soy milk, in addition to FSC, had a therapeutic effect. However, the antiallergy effects of FSC in terms of AD were far superior to those of soy milk. These results indicated that FSC can be used as a treatment for AD.
Kim, Chang-Hwan;Ko, Kyung-Ho;Huh, Yoon-Hyuk;Cho, Lee-Ra;Park, Chan-Jin
Journal of Dental Rehabilitation and Applied Science
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v.35
no.2
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pp.90-97
/
2019
Purpose: Previous studies related with occlusal contact area were limited that interocclusal thickness level or the method of measurement has not been accurate in measuring. The purpose of this study was to investigate the relation between head posture and occlusal contact area using photo occlusion analysis. Materials and Methods: 54 subjects with complete dentition (44 men, 10 women / 23 to 33 years of age) were included. To identify the relationship between head posture and occlusal contact area, subjects took interocclusal record in maximal intercuspal position with three different positions(supine position ($0^{\circ}$) / inclined position ($45^{\circ}$) / upright position ($90^{\circ}$)) on the dental unit chair. Occlusal contact area was analyzed using photo occlusion analysis. Statistical analyses were performed with SPSS ver.25.0 at 95% confidence interval. Results: Head posture has no significant effect on the changes of occlusal contact area (P > 0.05). Conclusion: When interocclusal relation is stable, head posture does not change a interocclusal record because head posture has no significant effect on occlusal contact area. Analysis of occlusal contact area using photo occlsion analysis device is useful due to its material property and simplicity.
Low carbon steel (S20C steel) and SPCC steel sheet have been austenitic nitrided at $700^{\circ}C$ in a closed pit type furnace by changing the flow rate of ammonia gas and heat treating time. When the flow rate of ammonia gas was low, the concentration of residual ammonia appeared low and the hardness value of transformed surface layer was high. The depth of the surface layer, however, was shallow. With increasing the concentration of residual ammonia by raising up the ammonia gas flow, both the depth of the surface layer and the pore depth increased, while the maximum hardness of the surface layer decreased. By introducing a large amount of ammonia gas in a short time, a deep surface layer with minimal pores on the outermost surface was obtained. In this experiment, while maintaining 10~12% of residual ammonia, the flow rate of inlet ammonia gas, 7 liter/min, was introduced at $700^{\circ}C$ for 1 hour. In this condition, the thickness of the surface layer without pores appeared about $60{\mu}m$ in S20C steel and $30{\mu}m$ in SPCC steel plate. Injecting additional methane gas (carburizing gas) to this condition played a deteriorating effect due to promoting the formation of vertical pores in the surface layer. For $1^{st}$ transformed surface layer for S20C steel, maintaining 10~12% residual ammonia condition via austenitic nitriding process resulted in ${\varepsilon}$ phase with relatively high nitrogen concentration (just below 4.23 wt.%N) among the mixed phases of ${\varepsilon}+{\gamma}$. The ${\varepsilon}$ phase was formed a specific orientation perpendicular to the surface. For $2^{nd}$ transformed layer for S20C steel, ${\gamma}$ phase was rather dominant (just above 2.63 wt.%N). For SPCC steel sheet, there appeared three phases, ${\gamma}$, ${\alpha}(M)$ and weak ${\varepsilon}$ phase. The nitrogen concentration would be approximately 2.6 wt.% in these phases condition.
Mooring bollards are the mandatory facility in ports for they are the objects used to fasten the ship to its position at the berth. All the mooring bollards were installed following suggested sizes, numbers, materials and shape of installation according to Port and Fishing Design Standards. However, Korea has no management standard for use of mooring bollards to safety in ship berthing. In this research, the installation standard for mooring bollards including the holding power applied to mooring bollards in berthing was studied. Also, the performance of mooring bollards for minimum safety guarantee in berthing based on research of various specification by their sizes was analyzed. The analysis on mooring bollards was examined by each power on mooring bollards from the applied force in berthing divided into horizontal and vertical direction in order to examine the performance of domestic mooring bollards, the limit force is calculated based on detailed specification research result. As a result, the working stress according to the towing force was found to be at least 150Mpa and it was evaluated to be 60% of the limit strength. Also, by comparing each forces, the appropriateness was examined and the specification of maximum capability calculated. This performance evaluation method based on detail specification of mooring bollards will be expected to be useful to examine the appropriateness of mooring bollards for various types of vessel in berthing and to develop maintenance and management standard through the performance change evaluation referring to mooring bollard detailed specification changes.
Kim, Gisuk;Kim, Moojoon;Ha, Kanglyeol;Lee, Jooho;Paeng, Dong-Guk;Choi, Min Joo
The Journal of the Acoustical Society of Korea
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v.38
no.4
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pp.459-466
/
2019
When a laser pulse is irradiated on a CNT (Carbon Nanotube) and PDMS (Poly dimethylsiloxane) composite coated on a transparent PMMA (Poly methyl methacrylate) substrate, a strong ultrasonic wave is generated due to the thermoelastic effect. In this paper, the thermoacoustic theory related to the wave generation by the CNT/PDMS composite was established. The waveforms of ultrasonic waves when a laser pulse having a Gaussian waveform is irradiated on the composite with a thickness of $20{\mu}m$ were numerically simulated. From the results, it was confirmed that ultrasonic shock waves can be generated from the CNT/PDMS composite and the waveforms are changed little even if the physical properties of the composite are changed by ${\pm}20%$. It was found that the peak positive and negative pressures increase as the thermal expansion coefficient increases, or as density, heat capacity and sound speed decreased. However, those changes were not so sensitive with thermal conductivity. In addition, the physical properties of the CNT/PDMS composite fabricated in this study were estimated from the comparison of the measurement and simulation results.
With recent innovations in the ICT industry, the demand for wearable sensing devices to recognize and respond to biological signals has increased. In this study, a three-dimensional (3D) spacer fabric was embedded in a single-wall carbon nanotube (SWCNT) dispersive solution through a simple penetration process to develop a monolayer piezoresistive pressure sensor. To induce electrical conductivity in the 3D spacer fabric, samples were immersed in the SWCNT dispersive solution and dried. To determine the electrical properties of the impregnated specimen, a universal testing machine and multimeter were used to measure the resistance of the pressure change. Moreover, to examine the changes in the electrical properties of the sensor, its performance was evaluated by varying the concentration, number of penetrations, and thickness of the specimen. Samples that penetrated twice in the SWCNT distributed solution of 0.1 wt% showed the best performance as sensors. The 7-mm thick sensors showed the highest GF, and the 13-mm thick sensors showed the widest operating range. This study confirms the effectiveness of the simple process of fabricating smart textile sensors comprising 3D spacer fabrics and the excellent performance of the sensors.
Journal of the Korean Society of Marine Environment & Safety
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v.27
no.1
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pp.145-152
/
2021
The purpose of this study was to determine the optimal distances between pipes to minimize the pressure loss and turbulent intensity. This was accomplished by investigating the distances between sleeve-jointed pipes and the flow changes in pipes based on variations in the Reynolds (Re) number when installing adjusting pieces for the pipes. When the thickness tp of the sleeve-jointed piping was fixed at 5 mm and the pipe lengths Lp were 10, 50, 100, and 200 mm, the correlations with the velocity of the sleeve-jointed part, pressure distribution, length of the reattachment point in the recirculation area, and Re number were analyzed. The flow characteristic of the sleeve-jointed part from a laminar to a turbulent flow region was determined by setting the Re range to 200 ≤ Re ≤ 5,000. This was done by utilizing Ansys Fluent 18.1, which is a commercial program. The enlargement and contraction ratios of the sleeve-jointed part were 1.2 and 0.83, respectively, and the turbulent intensity of the sleeve downstream edge and pressure change both increased as the Re number increased while Lp remained constant. The fact that the flow on the sleeve wall surface was disturbed by tp resulted in losses in velocity energy. Therefore, the edge of the sleeve-jointed part was also effected. When Lp was 10 mm or less, the turbulent intensity of the edge part did not change significantly as the Re number increased. The reattachment point in the recirculation area did not appear at Lp of 10 mm or less and was not affected by the vortex. In the case of 3,000 ≤ Re, the reattachment length of the wall surface of the sleeve-jointed part was nearly constant as Lp increased.
Background: The effect of ginsenoside Rh2 (G-Rh2) on mast cell-mediated anaphylaxis remains unclear. Herein, we investigated the effects of G-Rh2 on OVA-induced asthmatic mice and on mast cell-mediated anaphylaxis. Methods: Asthma model was established for evaluating airway changes and ear allergy. RPMCs and RBL-2H3 were used for in vitro experiments. Calcium uptake, histamine release and degranulation were detected. ELISA and Western blot measured cytokine and protein levels, respectively. Results: G-Rh2 inhibited OVA-induced airway remodeling, the production of TNF-α, IL-4, IL-8, IL-1β and the degranulation of mast cells of asthmatic mice. G-Rh2 inhibited the activation of Syk and Lyn in lung tissue of OVA-induced asthmatic mice. G-Rh2 inhibited serum IgE production in OVA induced asthmatic mice. Furthermore, G-Rh2 reduced the ear allergy in IgE-sensitized mice. G-Rh2 decreased the ear thickness. In vitro experiments G-Rh2 significantly reduced calcium uptake and inhibited histamine release and degranulation in RPMCs. In addition, G-Rh2 reduced the production of IL-1β, TNF-α, IL-8, and IL-4 in IgE-sensitized RBL-2H3 cells. Interestingly, G-Rh2 was involved in the FcεRI pathway activation of mast cells and the transduction of the Lyn/Syk signaling pathway. G-Rh2 inhibited PI3K activity in a dose-dependent manner. By blocking the antigen-induced phosphorylation of Lyn, Syk, LAT, PLCγ2, PI3K ERK1/2 and Raf-1 expression, G-Rh2 inhibited the NF-κB, AKT-Nrf2, and p38MAPK-Nrf2 pathways. However, G-Rh2 up-regulated Keap-1 expression. Meanwhile, G-Rh2 reduced the levels of p-AKT, p38MAPK and Nrf2 in RBL-2H3 sensitized IgE cells and inhibited NF-κB signaling pathway activation by activating the AKT-Nrf2 and p38MAPK-Nrf2 pathways. Conclusion: G-Rh2 inhibits mast cell-induced allergic inflammation, which might be mediated by the AKT-Nrf2/NF-kB and p38MAPK-Nrf2/NF-κB signaling pathways.
Journal of Practical Agriculture & Fisheries Research
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v.24
no.4
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pp.30-34
/
2022
This study was carried out to analyze the effect of changes in the light environment caused by the daylight disturbance on the productivity and quality of the standard cut flower rose cultivar 'Monet'. It was artificially shaded to obstruct the sunlight and the productivity and growing characteristics of roses according to the time of daylight disturbance were investigated. The number of cut flowers per unit area (3.3m2) of the cut flower rose 'Monet' was 40 stems in the control, while in the 4-hour, 8-hour, and 12-hour treatments, it was 32, 29, and 25, respectively. As the daylight disturbance time was increased, the number of cut flowers showed a tendency to decrease. In the case of cut flower characteristics related to the quality of cut roses, all characteristics such as flower width, flower height, petal length, and petal width, decreased by 10 to 20% in the 12-hour treatment compared to the control. In addition, growth characteristics such as peduncle length, peduncle thickness, and cut flower height, which determine the marketability of cut roses, also tended to decrease as the daylight disturbance time increased. On the other hand, the number of days to flowering increased by 14.0% from 24.3 to 27.7. The overall growth characteristics were contracted and flowering was delayed as the time of daylight disturbance increased. In the results of this study, as the daylight disturbance time increased, flower size, cut flower length, and fresh weight was decreased. This is due to the decrease in the total photosynthetic amount as the daily average photosynthetic photon flux density (PPFD) was decreased, resulting in a decrease in the quality of roses. It is judged that it is because they do not receive enough carbohydrates necessary for growth and development.
Journal of the Korean Academy of Esthetic Dentistry
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v.30
no.2
/
pp.53-58
/
2021
The attractiveness of the gingiva is determined by its color, shape, and the shape and location of the boundary between the teeth and the gingival tissue. The standards beauty, balance, and health of the gingiva are all different, but the general public would agree that a coral pink gingiva is more beautiful than black or brown gingiva. Hence, one would be able to smile more confidently in public if he or she receives a gingival pigmentation removal surgery that changes the color of black or brown gums to a beautiful pink color with relative simplicity. The color of one's gingiva varies from pale pink to deep bluish purple, depending on many health components. The most prominent among these include the vascular supply, epithelial thickness, the degree of keratinization, and the presence of pigment in the epithelium. Melanin, carotene, reduced hemoglobulin, and oxyhemoglobulin are the main pigments contributing to the normal color of the oral mucosa. The health of one's gingival tissue are essential for an attractive smile. Excessive melanin deposits in the basal and early basal layers of the epithelium stored in the form of melanosomes frequently cause pigmentation. Although there are many different procedures to remove this pigmentation, the it was removed using the Er;YSGG laser. It is my wish that, through this case study, many people
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