• The Journal of Korean Physical Therapy
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• 제21권3호
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• pp.95-102
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• 2009

Purpose: This study evaluates MCP-1 expression in the dorsal horn of a rat model of lumbar disc herniation by an autograft of the nucleus pulposus to the spinal nerve. Methods: After a coccygeal nucleus pulposus graft to the left $5^{th}$ lumbar spinal nerve, proximal to dorsal root ganglion, mechanical allodynia and thermal hyperalgesia were assessed 1 day before surgery, and 1, 10, 20, 30 days after surgery. The mRNA of MCP-1 in the dorsal horn was assessed by real time PCR to compare the temporal pattern of neuropathic pain of the lumbar disc herniation model. Results: In the ipsilateral side of the lumbar disc herniation models, mechanical allodynia and thermal hyperalgesia reached a maximum at 10 days after surgery with significant difference from the control group. Pain was also provoked in the contralateral side of the lumbar disc herniation models with less intensity than the ipsilateral side. The level of MCP-1 mRNA expression in the dorsal horn reached a peak at 20 days after surgery. Conclusion: Mechanical allodynia and thermal hyperalgesia was induced by nucleus pulposus in a rat lumbar disc herniation model, similar to a previously reported peripheral nerve injury model. The level of MCP-1 expression was higher in the dorsal horn of the ipsilateral and contralateral sides. These results suggest that MCP-1 might play a role in the maintenance of neuropathic pain.

• 한국운동역학회지
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• 제29권4호
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• pp.227-235
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• 2019

Objective: The purpose of this study was to evaluate the effect of passive-acute temperature therapy of the femoral muscle and dynamic warm-up on the countermovement jump performance. Method: Twenty male track and field athletes from national team underwent three treatments applied on the femoral muscles; cold temperature treatment, thermal treatment and dynamic warm-up. The variables extracted at 2 time points (pre-measurement and post measurement) were the temperature of the left and right femoral muscle, displacement & velocity of centre of mass, peak power out, range of motion and moment & power of the knee joint. Results: There was a statistically significant difference in the temperature of the femoral muscle according to measurement time which was high in the order of thermal treatment, dynamic treatment and cold treatment. The jump height was the highest in the dynamic warm-up with no statistically significant difference for the range of motion of the knee joint. The peak power out at dynamic warm-up and the power of the knee joint were statistically significant according to the treatment and measurement time. Conclusion: Local cold and thermal treatment of femoral muscles at ambient temperature did not improve jump performance, while dynamic warm-up was considered to be effective for maintaining the performance of the activities that require strong muscular power.

• Journal of Korean Biological Nursing Science
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• 제12권2호
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• pp.81-88
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• 2010

Purpose: The purpose of this study was to compare effects of intravenous fluid warming and forced-air warming on perioperative body temperature, Blood Pressure, Pulse and thermal discomfort after gastrectomy under general anesthesia. Methods: Data collection was performed from October, 2009 to February, 2010. The intravenous fluid warming group (27) was warmed through an IV line by an Animec set to $37^{\circ}C$. The forced-air warming group (27) was warmed by Bair Hugger System. The warming continued from induction of general anesthesia to two hours after completion of surgery. The data was analyzed by t-test, $X^2$, repeated measures ANOVA using SPSS/WIN 17.0. Results: There was a significant difference of body temperature and thermal discomfort between the intravenous fluid warming group and the forced-air warming group. Conclusion: We need to explore the effects combination of the intravenous fluid warming and the forced-air warming, and other warming therapy and the efficiency of modalities with regards to cost benefit is also needed.

• 전자공학회논문지
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• 제51권10호
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• pp.210-212
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• 2014

전립선 질환은 대표적인 남성질환 중의 하나이다. 전립선 비대증은 전립선 질환 중의 하나로 배뇨 통증 등을 유발한다. 전립선 질환을 치료하기 위한 방법으로는 수술적, 약물적 방법 등이 있다. 그러나 이러한 방법은 역생성 자성 및 발기부전증 등의 후유증 및 합병증 발생한다. 이러한 문제를 해결하기 위해서 최근에는 온열 요법을 이용한 치료가 급증하고 있다. 본 연구에서는 이러한 온열 치료를 위해서 전립선의 해부학적 위치와 열선의 인체공학적으로 설계하여 시스템을 구성하였다. 본 연구에서 개발 된 시스템의 성능을 파악하기 위해서 돼지 조직을 이용한 열전달 성능을 검증하였다.

• Medical Lasers
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• 제8권2호
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• pp.74-79
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• 2019

Periorbital melasma is often refractory to treatment and highly associated with rebound hyperpigmentation or mottled hypopigmentation after laser treatment in Asian patients. In this report, we describe 2 patients with cluster-1 periorbital melasma and 1 patient with cluster-2 periorbital melasma who experienced remarkable clinical improvements after microwave-generated, atmospheric-pressure, non-thermal nitrogen plasma treatments. All patients exhibited limited clinical responses after combination treatments with topical bleaching agents, systemic oral tranexamic acid, and low-fluenced Q-switched neodymium (Nd):yttrium-aluminum-garnet (YAG) lasers. Low-energy nitrogen plasma treatment at 0.75 J elicited remarkable clinical improvement in the periorbital melasma lesions without post-laser therapy rebound hyperpigmentation and mottled hypopigmentation. We deemed that a single pass of nitrogen plasma treatment at 0.75 J induces mild microscopic thermal tissue coagulation and modification within the epidermis while preserving the integrity of the basement membrane in patients with periorbital melasma. Accordingly, nitrogen plasma-induced dermal tissue regeneration could play a role in the treatment of melasma lesions.

• Journal of Acupuncture Research
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• 제30권5호
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• pp.41-50
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• 2013

Objectives : This study was performed to compare the effects of Shinbaro pharmacopuncture therapy and bee venom pharmacopuncture therapy in lumbar disc herniation Methods : We compared treatment efficacy of 12 patients with Shinbaro pharmacopuncture therapy and 10 patients with bee venom pharmacopuncture therapy, all of whom were diagnosed with lumbar disc herniation using computed tomography(CT) or magnetic resonance imaging(MRI). We performed a retrospective comparison and analysis during the course of 21 days since admission. To evaluate the treatment efficacy, we recorded the temperatures of the opposite back, hip, and legs with visual analog scale(VAS, back and legs), pain rating scale(PRS), Oswestry disability index(ODI) and digital infrared thermal imaging(DITI) based on patients' medical records. Results : Both treatments were effective in reducing pain and improving functions for lumbar disc herniation patients in terms of VAS, PRS, ODI, DITI. Shinbaro pharmacopuncture group showed slightly better results than the bee venom pharmacopuncture group, but the difference was not significant. Conclusions : For the treatment of lumbar disc herniation, it is suggested that Shinbaro pharmacopuncture therapy is thought to be as effective as bee venom pharmacopuncture therapy without side effects, although further study would be necessary.

• 대한임상전기생리학회지
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• 제4권1호
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• pp.63-83
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• 2006

This study conducted the following experiment to examine anesthetic effects of 500 kHz ultrasound with lidocaine. Clinical experiment was conducted to compare local anesthetic effects by ultrasound frequencies and drugs with 40 normal adults and it divided subjects into experimental group (I) applying only ultrasound, ointment group (II) applying only lidocaine, phonophoresis group of 1 MHz (III), phonophoresis group of 500 kHz lidocaine (IV) for pain threshold and nerve conduct experiments. Mechanical threshold was measured with von Frey monofilament, thermal pain threshold with halogen lamp and digital thermometer, action potential in median nerve with diagnostic electromyography before and after treatment, and at 30 min., 60 min., 90 min., and 120 min. after treatment. Results of this study can be summarized as follows. Topical anesthesia experiment showed that pain threshold of phonophoresis groups was significantly increased, but there were little differences in ultrasound frequency and drugs among phonophoresis groups. Conduction anesthesia experiment showed that phonophoresis group of 500 kHz using lidocaine had significant difference in pain threshold and sensory nerve conduction compared to ointment group and ultrasound group, but there was no great difference from other phonophresis groups and light nerve block effect was found. It was considered that application of 500 kHz ultrasound using lidocaine will be more effective in deep anesthesia or nerve block than 1 MHz ultrasound. However, researches considering various frequencies, intensities and application hours in low frequency areas including kHz ultrasound are needed to increase deep permeation of drugs.

• 대한물리의학회지
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• 제12권2호
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• pp.1-8
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• 2017

PURPOSE: The purpose of this study was investigate the changes of gastrocnemius (GCM) muscle activity by applying different hot and cold therapeutic modalities. METHODS: A total of 20 healthy subjects were enrolled into the study. We selected transfer modalities that are frequently used in clinical settings: conduction, radiation, and convection. We performed hot pack, ice pack, and infrared therapy for 10, 20, and 30 minutes. After each application, a break was taken between each day. In addition, we performed cryotherapy for 3 min (airflow rate = $-6{\sim}-20^{\circ}C$). We measured muscle activity changes in the GCM muscle. RESULTS: For the conduction method, muscle activity significantly increased after ice pack therapy for 10 min and 20 min but decreased after hot pack therapy for 10 min and 20 min. For the radiation method, muscle activity significantly decreased after infrared therapy for 10 min and 20 min. For the convection method, muscle activity significantly increased after cryotherapy for 3 min and 10 min. There were no differences in the change of muscle activity in the conduction and radiation transfer method using heat. However, there were differences in the change of muscle activity in the conduction and convection transfer method with cold application. CONCLUSION: For a reduction in muscle activity, regardless of the transfer type, thermal application for 20 min would be effective. For an increase in muscle activity, cold pack application or cryotherapy for 20 min would be effective. This study could contribute toward therapeutic modality application in changing muscle activity.

• Nuclear Engineering and Technology
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• 제55권4호
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• pp.1280-1286
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• 2023

MgF₂ as a moderator material has been extensively used in the beam shaping assembly (BSA) that plays an important role in the boron neutron capture therapy (BNCT). Regarded as important for applications, the thermal neutron scattering data of MgF₂ were calculated, based on the phonon expansion model. The structural properties of MgF₂ were researched by the VASP code based on the ab-initio methods. The PHONOPY code was employed to calculate the phonon density of states. Furthermore, the NJOY code was used to calculate the thermal neutron scattering data of MgF₂. The calculated inelastic cross sections plus absorption cross sections are in agreement with the available experimental data. The neutron transport in the BSA has been simulated by using a hybrid Monte-Carlo-Deterministic code NECP-MCX. The results indicated that compared with the calculation of the free gas model, the thermal neutron flux and epithermal neutron flux at the BSA exit port calculated by using the thermal neutron scattering data of MgF₂ were reduced by 27.7% and 8.2%, respectively.

• 대한의료기공학회지
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• 제13권1호
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• pp.1-18
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• 2013

Objective : The objective of this study is to report the effectiveness of conservative treatment on simple pelvic fracture with ostomy. Methods : A female patient 65 years old with ostomy, who were diagnosed as simple pelvic fracture by X-ray, were treated with conservative treatment by herbal medication with acupuncture and physical therapy. We evaluated the effectiveness by checking X-ray, Digital Infrared Thermal Imaging(D.I.T.I.). Results : The symptoms of the patient got improved and X-ray showed the fracture were healing. Conclusions : Conservative korean medical treatment can be effectively used for a patient with simple pelvic fracture and ostomy.