• Maxillofacial Plastic and Reconstructive Surgery
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• v.30 no.1
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• pp.11-21
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• 2008

Aim of the study: Thermal stress is a central determinant of osseous surgical outcomes. Interestingly, the temperatures measured during endosseous surgeries coincide with the temperatures that elicit the heat shock response of mammalian cells. The heat shock response is a coordinated biochemical response that helps to protect cells from stresses of various forms. Several protective proteins, termed heat shock proteins (hsp) are produced as part of this response. To begin to understand the role of the stress response of osteoblasts during surgical manipulation of bone, the heat shock protein response was evaluated in osteoblastic cells. Materials & methods: With primary cell culture studies and ROS 17/2.8 osteoblastic cells transfected with hsp27 encoding vectors culture studies, the thermal stress response of mammalian osteoblastic cells was evaluated by immunohistochemistry and western blot analysis. Results: Immunocytochemistry indicated that hsp27 was present in unstressed osteoblastic cells, but not fibroblastic cells. Primarily cultured osteoblasts and fibroblasts expressed the major hsp in response to thermal stress, however, the small Mr hsp, hsp27 was shown to be a constitutive product only in osteoblasts. Creation of stable transformed osteoblastic cells expressing abundant hsp27 protein was used to demonstrate that hsp27 confers stress resistance to osteoblastic cells. Conclusions: The demonstrable presence and function of hsp27 in cultured bones and cells implicates this protein as a determinant of osteoblastic cell fate in vivo.

• Journal of Acupuncture Research
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• v.31 no.2
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• pp.21-30
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• 2014

Objectives : Manufacturing and manipulation techniques of acupuncture can be interpreted as an induced electromagnetic viewpoint, as proposed in previous study. Considering from this point of view, the magnetization of needles should be essential to enhance the electromagnetic effects during the behavior of the acupuncture needling. Methods : The current disposable needles are made of non-magnetic stainless steels, so ferromagnetic materials were searched as suitable substitutes. Meanwhile, at the practical view, stainless steels are very available for the several superior properties like as corrosion resistance, strength, etc., magnetic stainless steels were first investigated. Some types of them still preserved the ferromagnetic properties of iron, so trial needles were made with them. And then magnetization of them were followed. Results : Among the hundreds types of stainless steels, martensitic or ferritic ones are ferromagnetic. The needles made with these ferromagnetic wires were magnetized, and polarized by magnetizer, and their magnetic properties were improved. Moreover, in addition to the superiority of the magnetism, the electrical and thermal conductivities of them were even better than those of the current austenitic stainless steels. Conclusions : Through the developmental study based on the electromagnetic viewpoint, the magnetized and polarized acupuncture needles were completed. This means that these needles having improved magnetism can be used to improve the electromagnetic needling effects, and moreover, their superiorities in the electrical and thermal conductivities can also give another benefits in treatments of electrical or warm needling.

• JSTS:Journal of Semiconductor Technology and Science
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• v.7 no.4
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• pp.254-259
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• 2007

In this report, several fabrication techniques for the formation of various nanochannels (with $SiO_2$, Si, or Quartz) are introduced. Moreover, simple fabrication technique for generating $SiO_2$ nanochannels without nanolithography is presented. By using different nanochannels, the degree of stretching DNA molecule will be evaluated. Finally, we introduce a nanometer scale fluidic channel with electrodes on the sidewall of it, to detect and analyze single DNA molecule. The cross sectional shape of the nanotrench is V-groove, which was implemented by thermal oxidation. Electrodes were deposited through both sidewalls of nanotrench and the sealing of channel was done by covering thin poly-dimethiysiloxane (PDMS) polymer sheet.

• Journal of Korean Physical Therapy Science
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• v.8 no.1
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• pp.727-734
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• 2001

Contracture is defined as the lack of full passive range of motion resulting from pint, muscle or soft tissue limitationprolonged Pint immobilization will result in stress and stretch deprivation and gradual development of contracture. the tissue changes caused by immobilization may be categorized as cellular modeling, ground substance and collagen response, and tissue response. contracture can be divided into three categories according to the anatomical location of pathological changes :arthrogenic, myogenic, soft tissue contractures Therapeutic approach of contracture is thermal or cold agents application, stretch or restoration of length, traction, manipulation, mobilization positioning and restoration of function. The purpose of this article is to review current concepts of mechanical properties and synthesis of collagen tissue and the underlying pathomechanics as it relates to evaluation and treatment of contracture.

• Journal of Korean Medical Ki-Gong Academy
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• v.13 no.1
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• pp.1-18
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• 2013

Objective : The objective of this study is to report the effectiveness of conservative treatment on simple pelvic fracture with ostomy. Methods : A female patient 65 years old with ostomy, who were diagnosed as simple pelvic fracture by X-ray, were treated with conservative treatment by herbal medication with acupuncture and physical therapy. We evaluated the effectiveness by checking X-ray, Digital Infrared Thermal Imaging(D.I.T.I.). Results : The symptoms of the patient got improved and X-ray showed the fracture were healing. Conclusions : Conservative korean medical treatment can be effectively used for a patient with simple pelvic fracture and ostomy.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.104-109
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• 2008

Distribution of welding residual stresses are mainly characterized by degrees and frequencies of thermal loads applied to materials. However, other effects as component size and clamping condition can also affect stress distributions to a certain extent thus careful manipulation of these parameters based on clear understanding of how they affect residual stresses distributions and why can be additional measure to mitigate residual stresses. This paper discusses aforementioned issues for the case of safety and relief nozzle in nuclear power plant through finite element analysis.

• Development and Reproduction
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• v.6 no.2
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• pp.71-76
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• 2002

Present study was aimed to summary the recent reports of chromosomal technology such like a polyploidv, sex differentiation, gynogenesis, transgenic fish and gene manipulation. Triploid cells for rainbow trout and channel catfish were induced through thermal shocks of varying temperature levels and produced as a industrial use. A monosex fish with homogametic females of 15 species of high valued fish were produced by exposing to irradiation. It seemed that different irradiation was suitable to inactivate the sperm and block the formation in producing the gynogenetic diploids. Since 1985, transgenic fish have been successfully produced by microinjecting or electroporating desired foreign DNA into unfertilized or newly fertilized eggs using about 40 fish species. More recently, transgenic fish have also been produced by infecting newly fertilized eggs with pantropic, defective retroviral vectors carrying desired foreign DNA. These transgenic fish can serve as excellent experimental models for basic scientific investigations as well as in marine biotechnological applications.

• Korean Journal of Poultry Science
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• v.48 no.4
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• pp.255-265
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• 2021

Global warming and scorching summer seasons affect the growth ability of broilers and animal welfare. In modern broilers, vital organs, such as the heart and lungs, grow disproportionally under intensive selection, making it difficult to adapt to warmer climates. Changes in environmental temperature can affect muscle formation during embryonic development and the early posthatching period. Satellite cells are highly sensitive to heat stress. Heat stress affects the proliferation and differentiation activity of satellite cells and muscle growth and structure. Therefore, thermal manipulation during broiler chick embryogenesis and environmental temperature management at the beginning of hatching are critical for the development and growth of broiler muscles. This review focuses on the thermoregulation mechanism of birds, the muscle development process of broilers, and the function of satellite cells, the relationship between heat stress and muscle development of chicks shortly after hatching, and studies on heat resistance and muscle growth of broilers.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2004.05a
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• pp.9-15
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• 2004

The copolymerization of HEMA with different hydrophilic and hydrophobic co-monomers allows for the manipulation of their intrinsic properties. 2-Hydroxyethylmethacrylate (HEMA)-based hydrogels thus are of great interest due to their outstanding physico-mechanical properties and chemical stability. The idea to use HEMA in order to create thermo-sensitive polymers was based on our assumption that thermal-sensitivity comes from a suitable hydrophilic-hydrophobic balance of macromolecules. In this work we have chosen N-vinyl pyrrolidone as a hydrophilic co-monomer with the relatively hydrophobic HEMA due to its good polymerizing properties as well as its non-toxicity in a polymer state and deserved recognition as a biocompatible material. As a result, copolymerization of NVP and HEMA was successful in obtaining new types of thermo-sensitive polymers composed of hydrophilic and hydrophobic monomers.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.11
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• pp.1064-1073
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• 2013

In this paper, a compact 370 W high efficiency GaN(Gallium Nitride) HEMT(High Electron Mobility Transistor) power amplifier(PA) using internal harmonic manipulation circuits is presented for cellular and L-band. We employed a new circuit topology for simultaneous high efficiency matching at both fundamental and 2nd harmonic frequency. In order to minimize package size, new 41.8 mm GaN HEMT and two MOS(Metal Oxide Semiconductor) capacitors are internally matched and combined package size $10.16{\times}10.16{\times}1.5Tmm^3$ through package material changes and wire bonded in a new package to improve thermal resistance. When drain biased at 48 V, the developed GaN HEMT power amplifier has achieved over 80 % Drain Efficiency(DE) from 770~870 MHz and 75 % DE at 1,805~1,880 MHz with 370 W peak output power(Psat.). This is the state-of-the-art efficiency and output power of GaN HEMT power amplifier at cellular and L-band to the best of our knowledge.