Proceedings of the Korean Institute of Information and Commucation Sciences Conference (한국정보통신학회:학술대회논문집)
- 2004.05a
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- Pages.9-15
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- 2004
THERMO-SENSITIVITY OF N-VINYL PYRROLODONE-CO-2- HYDROXYETHYLMETHACRYLATE HYDROGELS
- Irina Nam (Korea Advanced Institute of Science and Technology, Department of Biomolecular and Chemical Engineering) ;
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Park, Jung-Ki
(Korea Advanced Institute of Science and Technology, Department of Biomolecular and Chemical Engineerin) ;
- Lee, Seong-Nam (Korea Advanced Institute of Science and Technology, Department of Biomolecular and Chemical Engineerin) ;
- Sung, Shi-Joon (Korea Advanced Institute of Science and Technology, Department of Biomolecular and Chemical Engineerin) ;
- Min, Yong-Jin (Korea Advanced Institute of Science and Technology, Department of Biomolecular and Chemical Engineering)
- Published : 2004.05.01
Abstract
The copolymerization of HEMA with different hydrophilic and hydrophobic co-monomers allows for the manipulation of their intrinsic properties. 2-Hydroxyethylmethacrylate (HEMA)-based hydrogels thus are of great interest due to their outstanding physico-mechanical properties and chemical stability. The idea to use HEMA in order to create thermo-sensitive polymers was based on our assumption that thermal-sensitivity comes from a suitable hydrophilic-hydrophobic balance of macromolecules. In this work we have chosen N-vinyl pyrrolidone as a hydrophilic co-monomer with the relatively hydrophobic HEMA due to its good polymerizing properties as well as its non-toxicity in a polymer state and deserved recognition as a biocompatible material. As a result, copolymerization of NVP and HEMA was successful in obtaining new types of thermo-sensitive polymers composed of hydrophilic and hydrophobic monomers.
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