• Asian-Australasian Journal of Animal Sciences
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• 제17권1호
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• pp.109-115
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• 2004

Three experiments were conducted to evaluate the effects of taurine (Tau) supplements on broiler growth performance, serum constituents and antibody production. In Exp. 1, 3 day old chicks received a basal diet supplemented with Tau at 0, 0.10, 0.20, 0.30 or 0.40% for 6 weeks. Although dietary Tau supplementing at 0.30 or 0.40% enhanced feed conversion and reduced feed consumption during 0 to 3 weeks (p<0.05), neither serum total cholesterol or anti-Newcastle disease virus (NDV) titer were affected. In Exp. 2, dietary Tau supplement at 0.25-0.75% enhanced feed conversion of broilers during 0 to 3 weeks, but daily gain and feed consumption were not affected. The 0.75% Tau supplement group displayed lower serum total cholesterol at 6 weeks (p<0.05) comparing with the control group but no difference in anti-NDV titers. In Exp. 3, broilers were treated with dietary Tau of 0 or 0.50% combined with low (0/0%), medium (0.18/0.08%), or high (0.36/0.16%) methionine (Met) levels for 6 weeks (0 to 3/3 to 6 weeks). The addition of Met significantly improved daily gain and feed conversion of broilers during 0 to 3 weeks (p<0.01). Dietary Tau interacted significantly with Met on daily gain and feed consumption. Broiler serum amino acids revealed that Met supplements only increased serum Met level, but only serum Tau level was enhanced as given dietary Tau supplementation. The broilers receiving Tau normalized serum triglycerides level by feeding with the low Met diet and tended to display higher anti-NDV titers (p<0.10). The experimental results suggest that the growth response obtained by Tau supplements results partly from interactions with sulfur amino acids. However, the modulation of the broiler lipid metabolism may be responsible for dietary Tau.

• 융합신호처리학회논문지
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• 제11권1호
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• pp.47-52
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• 2010

암호화 시스템에서 대부분의 선형시스템은 쉽게 해석될 수 있기 때문에 비선형성은 매우 중요하다. 비선형 함수인 bent함수와 유사한 특성을 갖고 C.Bracken, Z.Zha 등에 의하여 제안된 APN(Almost Perfect Nonlinear) 함수를 이용하여 두 종류의 새로운 부호계열 발생 알고리즘을 제안하였다. 이를 이용하여 GF(2)상에서 발생된 부호계열의 자기상관함수 $R_{ii}(\tau)$, ${\tau}\;{\neq}\;0$와 상호상관함수 $R_{ik}(\tau)$의 값은 {-1, $-1-2^{n/2}$, $-1+2^{n/2}$}을 가진다. 이 개념을 확장한 GF(p), $p\;{\geq}\;3$상에서 발생된 비 이원부호계열의 자기상관함수 $R_{p,ii}(\tau}$, ${\tau}\;{\neq}\;0$와 상호상관함수 $R_{p,ik}(\tau)$의 값은 {$-1+p^{n-1}$, $-1-p^{(n-1)/2}+p^{n-1}$, $-1+p^{(n-1)/2}+p^{n-1}$} 로 역시 3종류 값을 가짐을 보였다. 이 분석결과로부터 발생된 부호계열의 상관함수가 Gold 부호계열과 유사한 특성을 가짐을 확인하였다.

• 폴리머
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• 제31권2호
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• pp.98-104
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• 2007

다양한 분자량의 폴리스티렌을 벤젠/n-헵탄, 1,4-다이옥산/이소프로판올, 1,4-다이옥산/n-헵탄과 같은 3종류의 혼합용매 계에 녹인 뒤 온도 상승에 따른 사슬의 팽창거동을 Flory $\Theta$온도 이상에서 점성도법으로 측정하였다. 온도 상승에 따라 두 종류의 영역, 즉 고분자 사슬이 팽창하는 영역과 수축하는 영역으로 구별되며, 분자량이 클수록 최대팽창온도가 높게 나타났다. 하나의 혼합용매 계 내에서는 $\tau/\tau_c$ 파라미터로 서로 다른 분자량의 사슬 팽창에 대하여 만능성이 나타나지만 서로 다른 혼합용매 계 사이에서는 각각의 기울기를 보임으로써 만능성이 관찰되지 않았다. 그러나 새로운 실험적 $b^{2/3}\tau/\tau_c$ 파라미터를 도입할 경우 모든 혼합용매 계의 사슬 팽창의 데이터들은 하나의 직선 위에 놓임으로써 만능성은 다시 회복되었다. 여기서 $\tau$는 $(T-\Theta)/\Theta$로 $\tau_c$는 $(\Theta-T_c)/T_c$로 각각 정의되며, $T_c$는 임계용액온도를 의미하며, b는 Schultz-Flory 식에서 $1/T_c$의 $1/M_w^{1/2}$에 대한 유효 기울기이다.

• Biomolecules & Therapeutics
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• 제31권1호
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• pp.127-138
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• 2023

Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer's disease (AD). In this study, structure-based virtual screening was performed to search database for compounds targeting GSK-3β from Enamine's screening collection. Of the top-ranked compounds, 7 primary hits underwent a luminescent kinase assay and a cell assay using human neuroblastoma SH-SY5Y cells expressing Tau repeat domain (Tau_RD) with pro-aggregant mutation ΔK280. In the kinase assay for these 7 compounds, residual GSK-3β activities ranged from 36.1% to 90.0% were detected at the IC₅₀ of SB-216763. In the cell assay, only compounds VB-030 and VB-037 reduced Tau aggregation in SH-SY5Y cells expressing ΔK280 Tau_RD-DsRed folding reporter. In SH-SY5Y cells expressing ΔK280 Tau_RD, neither VB-030 nor VB-037 increased expression of GSK-3α Ser21 or GSK-3β Ser9. Among extracellular signal-regulated kinase (ERK), AKT serine/threonine kinase 1 (AKT), mitogen-activated protein kinase 14 (P38) and mitogenactivated protein kinase 8 (JNK) which modulate Tau phosphorylation, VB-037 attenuated active phosphorylation of P38 Thr180/ Tyr182, whereas VB-030 had no effect on the phosphorylation status of ERK, AKT, P38 or JNK. However, both VB-030 and VB-037 reduced endogenous Tau phosphorylation at Ser202, Thr231, Ser396 and Ser404 in neuronally differentiated SH-SY5Y expressing ΔK280 Tau_RD. In addition, VB-030 and VB-037 further improved neuronal survival and/or neurite length and branch in mouse hippocampal primary culture under Tau cytotoxicity. Overall, through inhibiting GSK-3β kinase activity and/or p-P38 (Thr180/Tyr182), both compounds may serve as promising candidates to reduce Tau aggregation/cytotoxicity for AD treatment.

• 충청수학회지
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• 제23권1호
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• pp.11-27
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• 2010

Let $\Omega$ be a domain with smooth boundary in ${\mathbb{C}}^{n+1}$ and let $p{\in}{\partial}{\Omega}$. Suppose that $\Omega$ is Kobayashi hyperbolic and p is of Catlin multi-type ${\tau}=({\tau}_0,{\ldots},{\tau}_n)$. In this paper, we show that $\Omega$ admits a $C^{k}$ contraction at p with $k{\geq}\mid{\tau}\mid+1$ if and only if $\Omega$ is biholomorphically equivalent to a domain defined by a weighted homogeneous polynomial.

• 충청수학회지
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• 제28권3호
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• pp.431-441
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• 2015

Topology may described a pattern of existence of elements of a given set X. The family ${\tau}(X)$ of all topologies given on a set X form a complete lattice. We will give some topologies on this lattice ${\tau}(X)$ using a topology on X and regard ${\tau}(X)$ a topological space. Our purpose of this study is to give new topologies on the family ${\tau}(X)$ of all topologies induced by old one and its ${\theta}$ topology and to compare them.

• 한국지능시스템학회논문지
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• 제12권3호
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• pp.269-274
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• 2002

We introduce (${\tau}_i$, ${\tau}_j$) fuzzy (r,s)-semiclosures and (${\tau}_i$, ${\tau}_j$)-fuzzy (r,s)-semiinteriors. Using the notions, we investigate some of characteristic properties of fuzzy pairwise (r,s)-semicontinuous, fuzzy pairwise (r,s)-semiopen and fuzzy pairwise (r,s)-semiclosed mappings.

• 대한수학회보
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• 제33권1호
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• pp.57-64
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• 1996

Let $(X, B, \mu)$ be a probability space. Then we say $\tau : X \to X$ is a measure-preserving transformation if $\mu(\tau^{-1} E) = \mu(E)$. and we call it an ergodic transformation if $\mu(\tau^{-1}E\DeltaE) = 0$ for a measurable subset E implies $\mu(E) = 0$. An equivalent definition is that constant functions are the only $\tau$-invariant functions.

• Korean Journal of Mathematics
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• 제7권2호
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• pp.315-320
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• 1999

In this paper, we introduce the subsupratopology and the productsupratopology. In particular, we will show the class induced by a restricted supratopology contains the restricted class induced by the supratopology.

• 호남수학학술지
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• 제20권1호
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• pp.57-65
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• 1998

In this paper, we consider properties of Dedekind eta-function, modular discrimiant, thata-series and Weierstrass ${\wp}$-function. We prove the integrablities of ${\Delta}({\tau})$ and ${\eta}({\tau})$. Also, we give explicit formulae about ${\Delta}({\tau})$ and ${\tau}(n)$.