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Development of Optimal Blank Shape Design Program Using the Initial Velocity of Boundary Nodes (초기 속도법을 이용한 최적 블랭크 설계 프로그램의 개발)

  • 심현보;이상헌;손기찬
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2002.05a
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    • pp.77-81
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    • 2002
  • A new method of optimal blank shape design using the initial nodal velocity (INOV) has been proposed for the drawings of arbitrary shaped cups. With the given information of tool shape and the final product shape, corresponding initial blank shape has been found from the motion of boundary nodes. Although the sensitivity method, the past work of Hynbo Shim and Kichan Son, has been proved to be excellent method to find optimal blank shapes, the method has a problem that a couple of deformation analysis is required at each design step and it also exhibits an abnormal behaviors in the rigid body rotation prevailing region. In the present method INOV, only a single deformation analysis per each design stage is required. Drawings of practical products as well as oil-pan have been chosen as the examples. At every case the optimal blank shapes have been obtained only after a few times of modification without predetermined deformation path. The deformed shape with predicted optimal blank almost coincides with the target shape at every case. Through the investigation the INOV is found to be very effective in the arbitrary shaped drawing process design.

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A Ser/Thr Specific Protein Kinase Activates the Mouse Rantes Gene after Lipolpolysaccharide STimulation

  • Kim, Youn-Uck;Kim, Youn-Hwoan;An, Duek -Jun;Kwon, Hyuk-Chu
    • Journal of Microbiology
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    • v.39 no.4
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    • pp.314-320
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    • 2001
  • Macrophages stimulated by lipopolysaccharide(LPS) from gram negative bacteria undergo activation of a group of immediate early genes including Rantes. The mouse Rantes gene promoter region contains an LPS rsponsive element(LPE) We detected 3 specific bands termed B1, B2 and 3 formed by the interaction of the LPE and proteins found in LPS-stimulated RAW 367.7 cells. An additional band B4 was determined to be an Ap-1 binding protein. The B1 band appears within 1 hour of LPS nuclear extracts from LPS-stimulation, and this protein kinase enhances B1 and formation. The B1 band can be converted to band B2/B3 by adding specific heparin column fraction purified Ser/Thr specific protein phosphatases PP-1 and PP-2A can stimulate the same conversion to about the same extent. Thus, the formation of the LRE sequence binding complex appears to be regulated by Ser/Thr protein kinase and one or more Ser/Thr specific phosphatases. At least four proteins are involved in the trgulation of the LRE-dependent Rants experssion: two binding factors that bind directly to the target sequences. and two factors that control their binding. The future purification and characterization of these binding pro-teins will reveal in detail the mechanism of Rantes gene activation after LPS stimulation.

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High Temperature Durability Amorphous ITO:Yb Films Deposited by Magnetron Co-Sputtering

  • Jung, Tae Dong;Song, Pung Keun
    • Journal of Surface Science and Engineering
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    • v.45 no.6
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    • pp.242-247
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    • 2012
  • Yb-doped ITO (ITO:Yb) films were deposited on unheated non-alkali glass substrates by magnetron cosputtering using two cathodes (DC, RF) equipped with the ITO and $Yb_2O_3$ target, respectively. The composition of the ITO:Yb films was controlled by adjusting the RF powers from 0 W to 480 W in 120 W steps with the DC power fixed at 70 W. The ITO:Yb films had a higher crystallization temperature ($200^{\circ}C$) than that of the ITO films ($170^{\circ}C$), which was attributed to both larger ionic radius of $Yb^{3+}$ and higher bond enthalpy of $Yb_2O_3$, compared to ITO. This amorphous ITO:Yb film post-annealed at $170^{\circ}C$ showed a resistivity of $5.52{\times}10^{-4}{\Omega}cm$, indicating that a introduction of Yb increased resistivity of the ITO film. However, these amorphous ITO:Yb films showed a high etching rate, fine pattering property, and a very smooth surface morphology above the crystallization temperature of the amorphous ITO films (about $170^{\circ}C$). The transmittance of all films was >80% in the visible region.

TATA-Binding Protein-Related Factor 2 Is Localized in the Cytoplasm of Mammalian Cells and Much of It Migrates to the Nucleus in Response to Genotoxic Agents

  • Park, Kyoung-ae;Tanaka, Yuji;Suenaga, Yusuke;Tamura, Taka-aki
    • Molecules and Cells
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    • v.22 no.2
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    • pp.203-209
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    • 2006
  • TBP (TATA-binding protein)-related factor 2 (TRF2) regulates transcription during a nuber of cellular processes. We previously demonstrated that it is localized in the cytoplasm and is translocated to the nucleus by DNA-damaging agents. However, the cytoplasmic localization of TRF2 is controversial. In this study, we reconfirmed its cytoplasmic localization in various ways and examined its nuclear migration. Stresses such as heat shock, redox agents, heavy metals, and osmotic shock did not affect localization whereas genotoxins such as methyl methanesulfonate (MMS), cisplatin, etoposide, and hydroxyurea caused it to migrate to the nucleus. Adriamycin, mitomycin C and ${\gamma}$-rays had no obvious effect. We determined optimal conditions for the nuclear migration. The proportions of cells with nuclei enriched for TRF2 were 25-60% and 5-10% for stressed cells and control cells, respectively. Nuclear translocation was observed after 1 h, 4 h and 12 h for cisplatin, etoposide and MMS and hydroxyurea, respectively. The association of TRF2 with the chromatin and promoter region of the proliferating cell nuclear antigen (PCNA) gene, a putative target of TRF2, was increased by MMS treatment. Thus TRF2 may be involved in genotoxin-induced transcriptional regulation.

Characterization of AI-doped ZnO Films Deposited by DC Magnetron Sputtering (DC 마그네트론 스퍼터링에 의해 증착한 AZO 박막의 특성)

  • Park, Yi-Seop;Lee, Seung-Ho;Song, Pung-Keun
    • Journal of Surface Science and Engineering
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    • v.40 no.3
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    • pp.107-112
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    • 2007
  • Aluminum doped zinc oxide (AZO) films were deposited on non-alkali glass substrate by DC magnetron sputtering with 3 types of AZO targets (doped with 1.0 wt%, 2.0 wt%, 3.0 wt% $Al_2O_3$). Electrical, optical properties and microstructure of AZO films have been investigated by Hall effect measurements, UV/VIS/NIR spectrophotometer, and XRD, respectively. Crystallinity of AZO films increased with increasing substrate temperature ($T_s$) and doping ratio of Al. Resistivity and optical transmittance in visible light were $8.8{\times}10^{-4}{\Omega}cm$ and above 85%, respectively, for the AZO film deposited using AZO target (doped with 3.0 wt% $Al_2O_3$) at $T_s$ of $300^{\circ}C$. On the other hand, transmittance of AZO films in near-infrared region decreased with increasing $T_s$ and doping ratio of Al, which could be attributed to the increase of carrier density.

Consumption Experiences and the Meaning of "Luxury" of Women (여성 소비자의 소비경험을 통해 본 "사치"의 의미분석)

  • Yoo, Hyun-Jung
    • Journal of Families and Better Life
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    • v.26 no.3
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    • pp.115-130
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    • 2008
  • By conducting an ethnographic interviewing for women who had been traditionally recognized as the subject in consumption and analyzing the perception that they had on luxuries and necessities, this study tried a naturalistic interpretation on a meaning of "(small) luxury" recently well known to everybody. The target of interview included 20 women in their 20s to 50s living in Seoul and Kyunggi region. The sampling was made in consideration of an age, marriage, occupation, and household income level, etc. The data analysis had the process of drawing a final theme after having a domain analysis and a taxonomy analysis. In so doing, (1) women's experience of consuming life was described; (2) The analysis was made on what they would pursue in a consuming life, with a focus on a symbolic nature of a consumption; (3) Lastly, through a naturalistic interpretation, a theme regarding a meaning that a "luxury" had for them was drawn. As a result of an analysis, 12 domains and 5 taxonomies were derived. On the basis of it, 3 themes were deduced with respect to a meaning that a "luxury" had under the women's experience of consumption.

Oral Erythema Multiforme: Case Report (구강내 다형홍반의 증례보고)

  • Roh, Byung-Yoon;Ahn, Jong-Mo;Yoon, Chang-lyuk;Ryu, Ji-Won
    • Journal of Oral Medicine and Pain
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    • v.38 no.1
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    • pp.1-5
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    • 2013
  • Erythema multiforme(EM), a blistering and ulcerative inflammatory disorder, affect skins or mucosa, and is thought to be triggered mainly by preceding infection, such as Herpes simplex virus, or exposure to drugs and medication, particular antibiotics or analgesics. Symptoms include typical cutaneous target lesions on skins and in case of oral manifestation, erosive and ulcerative lesions on lips, buccal mucosa, and tongue are known to occur, which needs differential diagnosis with other intraoral lesions. In this case, EM assumed that it is occurred by giving Trichomonas infection or Metronidazole in oral region is introduced with a review of diagnosis and treatment of EM.

Developing the Jagalchi Marine Tour Complexes - Focusing on Foods - (자갈치 수산관광단지 조성방안에 관한 연구 - 먹거리를 중심으로 -)

  • Yoon, Tae-Hwan;Park, Bong-Gyu;Cho, Yong-Bum
    • Culinary science and hospitality research
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    • v.14 no.2
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    • pp.293-302
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    • 2008
  • The objective of this study is to suggest development methods of marine tour complexes by specializing and modernizing the renowned Jagalchi Fish Market. This study tries to suggest the ways of overcoming limitations of the traditional market place and making a unique tourism destination with affluent attractive culture elements. To preserve its position as the most famous fish market in Korea, Jagalchi market needs to more differentiate its position over competitors. To do that, it needs to avoid over-lapping of product categories among different sectors and specializing each zone according to the assigned theme. Improving tourism environments by expanding entertaining aspects, building landmark facilities and a seaside park, and tourism infrastructures. In addition, the development scheme needs to be planned unified with other city development plans to create a unified image, and a connection program with other tourism resources surrounding the target area needs to be created in order to pursue synergy effects. In the aspect of food, a large seafood center which offers various seafood from all around the world, a traditional night market street, various theme restaurants can be suggested. Successful development of the Jagalchi marine tour complexes not only has ripple effects on the region's culture, society, and other related industries but directly influences related regional tourism and commercial industry.

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FRACTAL DIMENSIONS OF INTERSTELLAR MEDIUM: I. THE MOLECULAR CLOUDS IN THE ANTIGALACTIC CENTER

  • LEE YOUNGUNG
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.137-141
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    • 2004
  • We have estimated the fractal dimension of the molecular clouds in the Antigalactic Center based on the $^{12}CO$ (J = 1- 0) and $^{13}CO$ (J = 1- 0) database obtained using the 14m telescope at Taeduk Radio Astronomy Observatory. Using a developed code within IRAF, we were able to identify slice-clouds, and determined the dispersions of two spatial coordinates as well as perimeters and areas. The fractal dimension of the target region was estimated to be D = 1.34 for low resolution $^{12}CO$ (J = 1 - 0) database, and D = 1.4 for higher resolution $^{12}CO$ (J = 1 - 0) and $^{13}CO$ (J = 1 - 0) database, where $P {\propto} A^{D/2}$. The sampling rate (spatial resolution) of observed data must be an important parameter when estimating fractal dimension. Our database with higher resolution of 1 arcminute, which is corresponding to 0.2 pc at a distance of 1.1 kpc, gives us the same estimate of fractal dimension to that of local dark clouds. Fractal dimension is apparently invariant when varying the threshold temperatures applied to cloud identification. According to the dispersion pattern of longitudes and latitudes of identified slice-clouds, there is no preference of elongation direction.

Probing the Starburst-AGN Connection in Type I AGN based on the 3.3 micron PAH lines

  • Woo, Jong-Hak;Kim, Ji-Hoon;Imanishi, Masatoshi
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.74.1-74.1
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    • 2011
  • To probe the connection between starburst and AGN activity, we investigate the relation between the 3.3 micron~PAH emission and AGN properties based on the new AKARI observations and the data collected from the literature. Using a sample of low-z Type I AGN, we measure the global 3.3 micron PAH luminosity from the AKARI slit-less spectroscopy. The 3.3 ${\backslash}$micron~PAH emissions are detected for 7 out of 26 target galaxies, but we find no strong correlation between the 3.3 ${\backslash}$micron~PAH emission and AGN luminosity, suggesting that global star formation may not be tightlyrelated with AGN activity. In contrast the to global star formation, the nuclear 3.3 micron~PAH emission luminosity, which are measured from ground-based long slit spectroscopy with a narrow slit, correlates with AGN luminosity. These results imply that starburst and AGN activity are directly connected at the nuclear region.

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