• 제목/요약/키워드: Target prediction

검색결과 816건 처리시간 0.025초

Prediction of Mammalian MicroRNA Targets - Comparative Genomics Approach with Longer 3' UTR Databases

  • Nam, Seungyoon;Kim, Young-Kook;Kim, Pora;Kim, V. Narry;Shin, Seokmin;Lee, Sanghyuk
    • Genomics & Informatics
    • /
    • 제3권3호
    • /
    • pp.53-62
    • /
    • 2005
  • MicroRNAs play an important role in regulating gene expression, but their target identification is a difficult task due to their short length and imperfect complementarity. Burge and coworkers developed a program called TargetScan that allowed imperfect complementarity and established a procedure favoring targets with multiple binding sites conserved in multiple organisms. We improved their algorithm in two major aspects - (i) using well-defined UTR (untranslated region) database, (ii) examining the extent of conservation inside the 3' UTR specifically. Average length in our UTR database, based on the ECgene annotation, is more than twice longer than the Ensembl. Then, TargetScan was used to identify putative binding sites. The extent of conservation varies significantly inside the 3' UTR. We used the 'tight' tracks in the UCSC genome browser to select the conserved binding sites in multiple species. By combining the longer 3' UTR data, TargetScan, and tightly conserved blocks of genomic DNA, we identified 107 putative target genes with multiple binding sites conserved in multiple species, of which 85 putative targets are novel.

산란점 정보를 이용한 표적 SAR 영상 간 유사도 평가기법 (Method for Similarity Assessment Between Target SAR Images Using Scattering Center Information)

  • 박지훈;임호
    • 한국군사과학기술학회지
    • /
    • 제22권6호
    • /
    • pp.735-744
    • /
    • 2019
  • One of the key factors for recognition performance in the automatic target recognition for synthetic aperture radar imagery(SAR-ATR) system is reliability of the SAR target database. To achieve optimal performance, the database should be constructed using the images obtained under the same operating condition as the SAR sensor. However, it is impractical to have the extensive set of real-world SAR images, and thus those from the electro magnetic prediction tool with 3-D CAD models are suggested as an alternative where their reliability can be always questionable. In this paper, a method for similarity assessment between target SAR images is presented inspired by the fact that a target SAR image is mainly characterized by the features of scattering centers. The method is demonstrated using a variety of examples and quantitatively measures the similarity related to reliability. Its assessment performance is further compared with that of the existing metric, structural similarity(SSIM).

Robust human tracking via key face information

  • Li, Weisheng;Li, Xinyi;Zhou, Lifang
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제10권10호
    • /
    • pp.5112-5128
    • /
    • 2016
  • Tracking human body is an important problem in computer vision field. Tracking failures caused by occlusion can lead to wrong rectification of the target position. In this paper, a robust human tracking algorithm is proposed to address the problem of occlusion, rotation and improve the tracking accuracy. It is based on Tracking-Learning-Detection framework. The key auxiliary information is used in the framework which motivated by the fact that a tracking target is usually embedded in the context that provides useful information. First, face localization method is utilized to find key face location information. Second, the relative position relationship is established between the auxiliary information and the target location. With the relevant model, the key face information will get the current target position when a target has disappeared. Thus, the target can be stably tracked even when it is partially or fully occluded. Experiments are conducted in various challenging videos. In conjunction with online update, the results demonstrate that the proposed method outperforms the traditional TLD algorithm, and it has a relatively better tracking performance than other state-of-the-art methods.

${\alpha}{\beta}$ 필터 및 NNPDA 알고리즘을 이용한 차량용 레이더 표적 추적 시스템 설계 (An Automotive Radar Target Tracking System Design using ${\alpha}{\beta}$ Filter and NNPDA Algorithm)

  • 배준형;현유진;이종훈
    • 대한임베디드공학회논문지
    • /
    • 제6권1호
    • /
    • pp.16-24
    • /
    • 2011
  • Automotive Radar Systems are currently under development for various applications to increase accuracy and reliability. The target tracking is most important in single or multiple target environments for accuracy. The tracking algorithm provides smoothed and predicted data for target position and velocity(Doppler). To this end, the fixed gain filter(${\alpha}{\beta}$ filter, ${\alpha}{\beta}{\gamma}$ filter) and dynamic filter(Kalman filter, Singer-Kalman filter, etc) are commonly used. Gating is used to decide whether an observation is assigned to an existing track or new track. Gating algorithms are normally based on computing a statistical error distance between an observation and prediction. The data association takes the observation-to-track pairings that satisfied gating and determines which observation-to-track assignment will actually be made. For data association, NNPDA(Nearest Neighbor Probabilistic Data Association) algorithm is proposed. In this paper, we designed a target tracking system developed for an Automotive Radar System. We show the experimental results of the 77GHz FMCW radar sensor on the roads. Four tracking algorithms(${\alpha}{\beta}$ filter, ${\alpha}{\beta}{\gamma}$ filter, 2nd order Kalman filter, Singer-Kalman filter) have been compared and analyzed to evaluate the performance in test scenario.

퍼지 예측을 이용한 이동물체 추적 (Tracking of Moving Object using Fuzzy Prediction)

  • 임용호;백중환;황수찬
    • 한국항행학회논문지
    • /
    • 제5권1호
    • /
    • pp.26-36
    • /
    • 2001
  • 시 변환 영상에서 가장 중요한 문제 중의 하나는 자동 목표 추적이다. 본 논문에서는 퍼지 예측을 이용한 이동물체의 위치예측 및 추적 기법을 제안한다. 먼저, 누적 차영상을 이용하여 물체와 배경을 분리한 다음 이동물체를 추출한다. 그리고 추출된 물체에 무게 중심법을 이용하여 물체의 중심점을 추출하고 추출된 물체에 가변 크기 탐색창을 사용하여 추적 성능을 높일 수 있는 기법을 제안한다. 또한 효율적인 물체 추적을 위한 조건으로 비선형적인 예측이 필요한데 본 논문에서는 다음 프레임에서의 물체의 위치를 예측하기 위해 퍼지 예측 방법을 제안한다. 실험을 통해 제안된 퍼지 예측 시스템이 여러 상황하에서 이동물체를 안정적으로 추적함을 보인다.

  • PDF

Analysis of delay compensation in real-time dynamic hybrid testing with large integration time-step

  • Zhu, Fei;Wang, Jin-Ting;Jin, Feng;Gui, Yao;Zhou, Meng-Xia
    • Smart Structures and Systems
    • /
    • 제14권6호
    • /
    • pp.1269-1289
    • /
    • 2014
  • With the sub-stepping technique, the numerical analysis in real-time dynamic hybrid testing is split into the response analysis and signal generation tasks. Two target computers that operate in real-time may be assigned to implement these two tasks, respectively, for fully extending the simulation scale of the numerical substructure. In this case, the integration time-step of solving the dynamic response of the numerical substructure can be dozens of times bigger than the sampling time-step of the controller. The time delay between the real and desired feedback forces becomes more striking, which challenges the well-developed delay compensation methods in real-time dynamic hybrid testing. This paper focuses on displacement prediction and force correction for delay compensation in the real-time dynamic hybrid testing with a large integration time-step. A new displacement prediction scheme is proposed based on recently-developed explicit integration algorithms and compared with several commonly-used prediction procedures. The evaluation of its prediction accuracy is carried out theoretically, numerically and experimentally. Results indicate that the accuracy and effectiveness of the proposed prediction method are of significance.

스미스 예측기와 그레이 예측 방법을 적용한 시간 지연이 있는 비 가시 환경에서의 원격로봇제어 (Teleoperation by using Smith prediction and Grey prediction with a Time-delay in a Non-visible Environment)

  • 정재훈;김덕수;이장명
    • 로봇학회논문지
    • /
    • 제11권4호
    • /
    • pp.277-284
    • /
    • 2016
  • A new prediction scheme has been proposed for the robust teleoperation in a non-visible environment. The positioning error caused by the time delay in the non-visible environment has been compensated for by the Smith predictor and the sensory data have been estimated by the Grey model. The Smith predictor is effective for the compensation of the positioning error caused by the time delay with a precise system model. Therefore the dynamic model of a mobile robot has been used in this research. To minimize the unstable and erroneous states caused by the time delay, the estimated sensor data have been sent to the operator. Through simulations, the possibility of compensating the errors caused by the time delay has been verified using the Smith predictor. Also the estimation reliability of the measurement data has been demonstrated. Robust teleoperations in a non-visible environment have been performed with a mobile robot to avoid the obstacles effective to go to the target position by the proposed prediction scheme which combines the Smith predictor and the Grey model. Even though the human operator is involved in the teleoperation loop, the compensation effects have been clearly demonstrated.

CR 시스템에서 Chaotic 예측기반 채널 센싱기법 (Chaotic Prediction Based Channel Sensing in CR System)

  • 고상;이주현;박형근
    • 전기학회논문지
    • /
    • 제62권1호
    • /
    • pp.140-142
    • /
    • 2013
  • Cognitive radio (CR) has been recently proposed to dynamically access unused-spectrum. Since the spectrum availability for opportunistic access is determined by spectrum sensing, sensing control is identified as one of the most crucial issues of cognitive radio networks. Out-of-band sensing to find an available channels to sense. Sensing is also required in case of spectrum hand-off. Sensing process needs to be done very fast in order to enhance the quality of service (QoS) of the CR nodes, and transmission not to be cut for longer time. During the sensing, the PU(primary user) detection probability condition should be satisfied. We adopt a channel prediction method to find target channels. Proposed prediction method combines chaotic global method and chaotic local method for channel idle probability prediction. Global method focus on channel history information length and order number of prediction model. Local method focus on local prediction trend. Through making simulation, Proposed method can find an available channel with very high probability, total sensing time is minimized, detection probability of PU's are satisfied.

BcN망에서 다중화된 MPEG 비디오소스의 QoS 보장 방식 (A Study on Guaranteed Quality of Service in Multiplexed MPEG video sources over BcN Network)

  • 박준열;이한영
    • 대한전자공학회논문지TC
    • /
    • 제43권3호
    • /
    • pp.78-83
    • /
    • 2006
  • 본 논문에서는 BcN 망에서 다중화된 MPEG 비디오 스트림을 전송 시 QoS를 보장하는 능동적 대역폭 할당 방법을 제안하였다. 실시간 처리를 위해 다중화 소스를 일정시간대별로 처리하는 '측정 대역폭 구간'으로 분류하고 단일 비디오 소스에서 사용되고 있는 선형예측 방법을 분석하여, 이 과정에서 만족할만할 품질 보장율을 얻지 못할 경우 보다 효율적으로 QoS를 보장하기 위한 능동적 대역폭 할당방법으로 과할당과 재할당의 분배방식을 이용한 두 가지 보장 방법을 제안하였다. 특성이 서로 다른 네 가지 비디오 소스를 트래픽 발생시기가 불규칙적이게 다중화시켜 생성한 랜덤 다중화소스와, 프레임내 I 픽쳐의 배열을 고려해서 생성시킨 GOP 다중화소스를 만들어 모의실험을 하였고 이를 통해 선형예측 방법의 성능평가와 제안된 과 할당 및 재할당방법의 성능을 비교평가 하였다. 실험 결과, 과할당방법과 재할당 방법 모두 측정구간을 1.8초 이상으로 하면 0.9이상의 대역폭 이용계수값에서 목표 품질 보장을 만족하면서 낮은 대역폭 점유를 얻을 수 있었고, 특히 대역폭의 효율적 운용의 경우 재할당방법이 같은 조건하에서 더 좋은 성능을 보임을 알 수 있었다.

Bioinformatic Prediction of SNPs within miRNA Binding Sites of Inflammatory Genes Associated with Gastric Cancer

  • Song, Chuan-Qing;Zhang, Jun-Hui;Shi, Jia-Chen;Cao, Xiao-Qin;Song, Chun-Hua;Hassan, Adil;Wang, Peng;Dai, Li-Ping;Zhang, Jian-Ying;Wang, Kai-Juan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권2호
    • /
    • pp.937-943
    • /
    • 2014
  • Polymorphisms in miRNA binding sites have been shown to affect miRNA binding to target genes, resulting in differential mRNA and protein expression and susceptibility to common diseases. Our purpose was to predict SNPs (single nucleotide polymorphisms) within miRNA binding sites of inflammatory genes in relation to gastric cancer. A complete list of SNPs in the 3'UTR regions of all inflammatory genes associated with gastric cancer was obtained from Pubmed. miRNA target prediction databases (MirSNP, Targetscan Human 6.2, PolymiRTS 3.0, miRNASNP 2.0, and Patrocles) were used to predict miRNA target sites. There were 99 SNPs with MAF>0.05 within the miRNA binding sites of 41 genes among 72 inflammation-related genes associated with gastric cancer. NF-${\kappa}B$ and JAK-STAT are the two most important signaling pathways. 47 SNPs of 25 genes with 95 miRNAs were predicted. CCL2 and IL1F5 were found to be the shared target genes of hsa-miRNA-624-3p. Bioinformatic methods could identify a set of SNPs within miRNA binding sites of inflammatory genes, and provide data and direction for subsequent functional verification research.