• Journal of Preventive Medicine and Public Health
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• v.45 no.4
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• pp.235-243
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• 2012

Objectives: Nail has been a substitute DNA source for genotyping. To investigate the integrity and consistency of nail DNA amplification for biomarker study, nail clippings from 12 subjects were collected at monthly intervals. The possibility of longer amplification and existence of GAPDH RNA/protein, were also investigated with three nail samples. Methods: Three primer sets were designed for quantitative amplification of nuclear and mitochondrial genes and analysis of their consistency. The mean threshold cycles in amplification of the target genes were compared to test the consistency of polymerase chain reaction (PCR) performance among individual factors including age groups, sex, family, the nail source, and by the size of the amplification segments. Results: The amplification of the target genes from nail DNA showed similar integrity and consistency between the nail sources, and among the serial collections. However, nail DNA from those in their forties showed earlier threshold cycles in amplification than those in their teens or seventies. Mitochondrial DNA (mtDNA) showed better DNA integrity and consistency in amplification of all three targets than did nuclear DNA (nucDNA). Over 9 kb of mtDNA was successfully amplified, and nested quantitative PCR showed reliable copy numbers (%) between the two loci. Reverse transcription PCR for mRNA and immunoblotting for GAPDH protein successfully reflected their corresponding amounts. Regarding the existence of RNA and protein in nails, more effective extraction and detection methods need to be set up to validate the feasibility in biomarker study. Conclusions: Nail DNA might be a feasible intra-individual monitoring biomarker. Considering integrity and consistency in target amplification, mtDNA would be a better target for biomarker research than nucDNA.

• Journal of The Geomorphological Association of Korea
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• v.21 no.4
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• pp.133-147
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• 2014

Reducing the range of target landform, is required to save the time and cost before real field survey in the case of inaccessible landform such as talus. In this study, Weight of Evidence modeling, which is a Target-driven spatial analysis statistics methods, has been applied to reduce the field survey range of target landform. In order to apply the Weight of Evidence analysis, a likelihood ratio was calculated on the basis of the result of correlation analysis between geomorphic factors and GIS information after selection of geomorphic factors regarding talus. A best combination, which has the biggest possibility for Talus Potential Index, was found by using SRC and AUC methods after calculating the number of cases for each thematic maps. This combination which includes aspect, geology, slope, land-cover, soil depth and soil drainage factors, showed quite high accuracy by 74.47% indicating the ratio of real existent talus to potential talus distribution.

• Journal of Aerospace System Engineering
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• v.16 no.5
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• pp.70-77
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• 2022

This paper proposes database generation and management system for small-pixelized airborne target recognition. The proposed system has five main features: 1) image extraction from in-flight test video frames, 2) automatic image archiving, 3) image data labeling and Meta data annotation, 4) virtual image data generation based on color channel convert conversion and seamless cloning and 5) HOG/LBP-based tiny-pixelized target augmented image data. The proposed framework is Python-based PyQt5 and has an interface that includes OpenCV. Using video files collected from flight tests, an image dataset for airborne target recognition on generates by using the proposed system and system input.

• Analytical Science and Technology
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• v.19 no.5
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• pp.441-448
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• 2006

11-nor-9-carboxy-${\Delta}^9$-tetrahydrocannabinol (THCCOOH) is the major metabolite of tetrahydrocannabinol (THC) which is the primary psychoactive component of marijuana. It is also the target analyte for the discrimination marijuana use. A method using solid-phase extraction (SPE) and gas chromatography/mass spectrometry (GC/MS) was developed for the determination of THCCOOH in human urine. Urine samples (3 mL) were extracted by SPE column with a cation exchange cartridge after basic hydrolysis. The eluents were then evaporated, derivatized, and injected into the GC/MS. The limits of detection (LOD) and quantitation (LOQ) were 0.4 and 1.2 ng/mL, respectively. The response was linear with a correlation coefficient of 0.999 within the concentration range of 1.2 (LLE 1.3)~50.0 ng/mL. The precision and accuracy were stable within 1.20% and the recovery was 83.6~90.7%. The recovery of SPE method was lower than that of liquid-liquid extraction (LLE), but there were no apparent differences in LOD, LOQ, precision and accuracy between the two methods. While SPE method is used as a very effective and rapid procedure for sample pretreatment, and clean extracts, LLE method was not suitable for the extraction procedure of THCCOOH in urine. The applicability of the method was proven by analyzing a urine samples from a marijuana abusers.

• Journal of the Korean Institute of Intelligent Systems
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• v.17 no.2
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• pp.265-269
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• 2007

In this paper, we propose an automatic extraction method of gastric cancer region from electronic endoscopic images. We use the brightness and saturation of HSI in removing noises by illumination and shadows by the crookedness occurring in the endoscopic process. We partition the image into several areas with similar pigments of hemoglobin using IHb. The candidate areas for gastric cancer are defined as the areas that have high hemoglobin pigments and high value in every channel of RGB. Then the morphological characteristics of gastric cancer are used to decide the target region. In experiment, our method is sufficiently accurate in that it correctly identifies most cases (18 out of 20 cases) from real electronic endoscopic images, obtained by expert endoscopists.

• Journal of Ocean Engineering and Technology
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• v.25 no.6
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• pp.9-16
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• 2011

The feasibility of wave energy extraction from a heaving truncated cylinder and the corresponding response of the linear electric generator (LEG) composed of spring, magnet, and coil has been investigated in the frame of three-dimensional linear potential theory. The heaving motion of a circular cylinder is calculated by means of the matched eigenfunction expansion method. Further, the analytical results are validated by numerical results using the ANSYS AQWA commercial code. By the action of a heaving circular cylinder, the magnet suspended by a spring can slide vertically inside the heaving cylinder. The mechanical power is extracted from the magnet motion relative to the coil/stator which is attached to the cylinder. The coupled ODE of a heaving cylinder and LEG system in waves is derived to obtain the magnet motion relative to a cylinder. To maximize the relative motion of the magnet, both the buoy draft and the LEG system parameters (spring stiffness, damping) should be selected properly for generating the double resonance considering the peak frequency of the target spectrum.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.3 no.2
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• pp.447-453
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• 1999

In MHD power generation system, enthalpy of the working gas is convened to electric power directly through expansion in generator channel. It means that electric power can be generated without a moving mechanical linkage such as turbine blades. The principle of MHD generation is based on Faraday'law of induction that eletromotive force(u$\times$B) is generated when the working gas of velocity u flows a channel in which magnetic field of strength(B) exists. In this paper, helium gas seeded with cesium is used as working gas. There are two types of generator in MHD generation; linear type faraday and disk type hall generator. Rogowski coils having the bandwidth of the 100(Hz) ~ 20(kHz) were used for measuring current flowing MHD disk channel. Optimum load resistor value of the MHD generator studied was 2.5[$\Omega$]. Disk type hall generator's generation performance is the main target of this paper, which superiors to linear type Faraday generator in many points. Isentropic efficiency and enthalpy extraction rate of disk type shock tube driven hall generator is discussed here.

• Journal of Korea Multimedia Society
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• v.11 no.5
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• pp.567-578
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• 2008

For analyzing a huge amount of web pages available in the Internet, we need to extract the encoded information in web pages. In this paper, we propose a method to extract and convert web information from web pages into XML documents for multidimensional analysis. For extracting information from web pages, we propose two languages: one for describing web information extraction rules based on the object-oriented model, and another for describing regular expressions of HTML tag patterns to search for target information. For multidimensional analysis on XML documents, we propose a method for constructing an XML warehouse and various XML cubes from it like the way we do for relational data. Finally, we show the validness of our method through the application to US patent web pages.

• Korean Journal of Remote Sensing
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• v.28 no.6
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• pp.623-632
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• 2012

In this paper, we analyzed the effect of wavelet decomposition levels in feature extraction for anomaly detection from hyperspectral imagery. After wavelet analysis, anomaly detection was experimentally performed using the RX detector algorithm to analyze the detecting capabilities. From the experiment for anomaly detection using CASI imagery, the characteristics of extracted features and the changes of their patterns showed that radiance curves were simplified as wavelet transform progresses and H bands did not show significant differences between target anomaly and background in the previous levels. The results of anomaly detection and their ROC curves showed the best performance when using the appropriate sub-band decided from the visual interpretation of wavelet analysis which was L band at the decomposition level where the overall shape of profile was preserved. The results of this study would be used as fundamental information or guidelines when applying wavelet transform to feature extraction and selection from hyperspectral imagery. However, further researches for various anomaly targets and the quantitative selection of optimal decomposition levels are needed for generalization.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.5 s.305
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• pp.157-164
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• 2005

The conventional adaptive detectors can not maintain sufficient detection performance at the presence of non-stationary clutter with unknown characteristics. This is caused by the lack of a priori information about clutter parameters changing over radar coordinates. To solve this problem, it is necessary to use clutter classifiers which have functions, such as the selection of the applied algorithm and its parameters extraction according to clutter conditions. In this paper, we describe the implementation of a clutter environment classifier for adaptive processing. In the environment classifier implemented on Visual C++, the extraction of the parameters and selection of processing algorithm for the adaptive processing unit are possible, and the result of algorithms can be verified at each stage.