• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2007년도 학술대회 1부
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• pp.881-886
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• 2007

오감 융합 정보 시대가 도래한다. 오감 융합은 감각 정보의 전이 기술 개발로 가능하다. 본 연구는 청각 정보의 촉각 정보 전이에 대한 연구이다. WMPlayer10SDK는 마이크로소프트사의 윈도우즈 미디어 플레이어(Windows Media Player, WMP)를 전용 소프트웨어 기반으로 하는 Plug-in 개발툴이다. WMPlayer10SDK 시스템은 WMP 내에서의 비디오와 오디오의 신호 정보를 추출하는 부분을 제공한다. 이를 이용하여 촉각 디스플레이(Tactile Display)장치인 Pos Tactor를 연동하여 음성 신호에서 진동 촉각을 제시하는 시스템을 개발하였다. 음성신호는 8bit, 16bit, 24bit, 32bit로 구분되며 각각의 주파수와 음폭의 Scale을 계산하여 그 수치를 시리얼 통신을 사용하여 통신포트(COM1)에 38400bps로 전달하여 구동하게 하였다. 이를 이용하여 음악을 촉감으로 느끼는 뮤직슈트(music suit)를 개발 하였다. 그러므로 뮤직슈트의 적용된 기술은 청각적 체험을 촉각적 체험을 할 수 있는 오감 융합 기술의 기초 기술로 제공 될 수 있다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.450-453
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• 2004

A tactile stimulator array using stacked PZT is fabricated and evaluated in this paper. The purpose of this research is the development of a tactile stimulator to represent the obstacle information for the visually disabled. As a first step of this research, we investigate the physiological characteristics of tactile stimuli and design a tactile stimulator based on the investigated results. Also we evaluated a fabricated tactile stimulator. The prototype of tactile stimulator which has 2$\times$2 tactor elements with 3mm spacing is fabricated using stacked PZT actuator. In order to evaluate the characteristics of this tactile stimulator, physiological experiments are carried out. In the experiment, the threshold of tactile stimulus intensity within a frequency range of 5-500Hz at various stimulus amplitudes are investigated. According to the obtained experimental result, the input signal of tactile stimulator for the effective transfer of obstacle information is determined. Also physiological experiments of multi-stimuli recognition such as shift and rotation are carried out

• Biomolecules & Therapeutics
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• 제12권2호
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• pp.62-67
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• 2004

Trauma remains one of the important sources leading to systemic inflammatory response anti sub-sequent multiple organ failure. Although hepatic microvascular dysfunction occurs during trauma, the mechanism responsible remains unclear. The aim of this study was to investigate the effect of trauma on hepatic vascular stress gene expression. Femur fracture (EFx) was induced by torsion to the femur at midshaft. Liver samples were taken for RT-PCR analysis of mRNA for gtenes of interest: endothelin-1 (ET-1), its receptors $ET_A$ and $ET_B$, nitric oxide synthases (iNOS and eNOS), cyclooxygenase-2 (COX-2), heme oxygenase-1 (HO-1), and tumor necrosis tactor-${\alpha}$ (TNF-${\alpha}$). The expression of ET-1 mRNA was significantly increased by FFx. Expression of mRNA in FFx group showed no change in $ET_A$, $ET_B$, iNOS and HO-1 and showed a slight increase of 2.2-fold and 2.7-fold for eNOS tll1d COX-2, respectively. The level of TNF-${\alpha}$ mRNA significantly increased in FFx group. In conclusion, mild trauma alone causes little change in expression of vasoactive mediators.

• 한국공작기계학회논문집
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• 제14권1호
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• pp.66-72
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• 2005

The working tactor of this study, an agriculture machine, is consisted of 4 wheel driving system with gear trains and 4-type wheel steering system. Since technological regions for 4 wheel driving system and 4-type wheel steering system are some large, we divide on two studies on 4 wheel driving system and 4-type wheel steering system This study develops transmission and axle that are very important units for strong working operation because the power of tractor is largely affected by transmission and axle. Even if the development of the power train is some common technology, it is very complicated work and needs many experience know-hows. So, for new given specifications fitted to the working tractor, a kind of new agriculture machine, this study haws out processes that are development of assembly drawing and strength analysis through classical method and CAE software for all internal parts and housing cases.

• 한국환경과학회지
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• 제17권5호
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• pp.573-580
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• 2008

This study aims to measure and to analyze the characteristics of thermal environment of the various permeable pavement materials such as a break stone pavement (Green block cubic), soil protection pavement (Soil tector), soil cement pavement and ceramic brick pavement under the summer outdoor environment. The thermal environment characteristics measured in the study includes the changes of surface temperature during the day, and long and short wave radiation of each pavement surface. The experimental condition is based on the data on the hottest temperature (August 9, 2006, $37.1^{\circ}C$) of the year. The albedo was the highest on the break stone pavement(0.8) from 12:00 to 14:00. The albedo of the ceramic brick pavement, a soil tector pavement and soil cement pavement were 0.35, 0.29 and 0.27 from 12:00 to 14:00, respectively. The peak surface temperature and long wave radiation was the highest on the soil protection pavements($56.6^{\circ}C$/627 W/$m^2$). The peak surface temperatures and long wave radiation on the ceramic brick pavement, a stone brick pavement and soil cement pavement were $51.7^{\circ}C$/627 W/$m^2$, $48.8^{\circ}C$/607 W/$m^2$ and $45.9^{\circ}C$/582 W/$m^2$, respectively. The heat environment was better on the break stone pavement than on the other pavements. This is mainly due to the high albedo of the break stone pavement(0.8) while the albedo value of a ceramic brick pavement, a soil tactor pavement and soil cement pavement were 0.35. 0.29 and 0.27. Large heat capacity($2,629kJ/m^3{\cdot}K$) of the stone brick pavements also contributes to this difference. The heat environment was better on the soil cement pavement than the soil tector pavement. This is mainly due to the evaporation of the soil cement pavement while the active evaporation of the soil tactor pavement was not continued after two days from the rainfall event. To improve the thermal environments in the urban area, it is recommended to raise the albedo of the pavements by brightening the surface color of the pavement materials. Further studies on the pavement materials and the construction methods which can enhance the continuous evapotranspiration from the pavements surface are needed.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.171-175
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• 2004

A tactile stimulator array using stacked PZT is fabricated and evaluated in this paper. The purpose of this research is the development of a tactile stimulator to represent the obstacle information for the visually disabled. As a first step of this research, we investigate the physiological characteristics of tactile stimuli and design a tactile stimulator based on the investigated results. Also we evaluated a fabricated tactile stimulator. The prototype of tactile stimulator which has 2x2 tactor elements with 3mm spacing is fabricated using stacked PZT actuator. In order to evaluate the characteristics of this tactile stimulator, physiological experiments are carried out. In the experiment, the threshold of tactile stimulus intensity within a frequency range of 5-500Hz and at various stimulus amplitudes are investigated. According to the obtained experimental result, the input signal of tactile stimulator for the transfer of obstacle information is determined. Also physiological experiments of multi-stimuli recognition such as shift and rotation are carried out.

• 한국표면공학회지
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• 제40권4호
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• pp.185-189
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• 2007

A scanning electron microscope (SEM) is a complex system, consisting of many sophisticated components. For a systematic characterization, a $2^4$ full factorial experiment was conducted. The SEM components examined include condenser lens 1 and 2 (denoted as A and B, respectively), and Objective lens (coarse and fine-denoted as C and D respectively). A statistical analysis was conduced to investigate factor effects and variations In response surfaces. Among four factors, main effect analysis revealed that A and D were Identified as the dominant factor. Moreover, B showed conflicting effect against C. The $R^2$ of statistical regression model constructed was about 69.6%. The model generated 3D response surface plots facilitated understanding of complex tactor effects.

• 대한기관식도과학회지
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• 제16권1호
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• pp.39-46
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• 2010

Background and Objectives Various tumor markers have been studied in an attempt to evaluate and decide the optimal treatment of the patients with head and neek squamous cell carcinoma (HNSCC). A nuclear antigen Ki-67 is a proliferative marker of tumor cells in all phases of cell cycle except G0. c-met gene, the tyrosine kinase receptor for hepatocyte growth tactor, may play various roles in malignant transformation. The authors evaluated the prognostic significance of Ki-67 and c-Met in surgical specimens of HNSCC to determine the relationship with the various clinicopathological characteristics. Materials and Methods Formatin-fixed paraffin-embedded surgical specimens were obtained from 54 patients with HNSCC. Ki-67 and c-Met expressions were analyzed by immunohistochemical staning and were compared with the clinicopathological characteristics such as, pathologic differentiation, tumor stage, clinical stage and lymph node metastasis. Results Ki-67 and c-Met over-expression was detected in 66.7% and 90.7% in HNSCC. There was positive correlation of increased expression of Ki-67 with tumor stage. and clinical stage, increased expression of e-Met with tumor stage, clinical stage, and nodal status. The expression of c-Met had a significant positive relationship with Ki-67 index (p<0.05). Conclusion Therefore, Ki-67 and c-Met are useful markers of tumor progression, aggressiveness and prognosis in HNSCC.

• 정보관리학회지
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• 제24권3호
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• pp.5-19
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• 2007

조직은 최종사용자 업무를 지원하기위한 새로운 정보시스템을 투자하고 있으며 이러한 정보시스템을 통한 이점은 정보센터의 효과적인 지원과 지원에 대한 사용자의 만족도에 의해 크게 좌우되어가고 있다. 정보센터는 정보 집약적이며 최신의 기술을 활용하여 조직의 역량을 전달하기 위해 사용자를 지원하므로 정보센터는 최종사용자 지원활동과 관련하여 매우 중요한 의미를 갖는다. 본 연구는 정보센터의 사용자 만족도와 관련된 정보제공, 신뢰제공, 그리고 시스템 제공역량과 같은 최종사용자 지원요인들을 살펴봄으로서 사용자만족도 향상을 위해 고려되어야 할 사항에 대해 논의하였다. 정보제공, 서비스 스텝의 신뢰성제공, 그리고 시스템제공 역량 등 18개의 잠재요인으로 252명의 사용자에 대한 설문내용을 기초로 3개의 가설을 검증하였다. 또한, 동일한 잠재요인에 대해 지원요인의 지각된 중요도와 수행정도의 차이를 통해 서비스 품질 격차를 조사하였다. 연구결과 정보제공 활동, 서비스 신뢰성제공 활동, 그리고 시스템 제공역량은 정보센터의 사용자 만족도에 유의한 영향을 미치는 것으로 파악되었으며, 사용자 만족도는 정보센터의 지원요인에 대한 지각된 중요도와 수 행정도에 대한 서비스 품질 격차의 정도에 의해서도 영향을 받는 것으로 밝혀졌다.

• 대한화장품학회지
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• 제35권1호
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• pp.65-72
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• 2009

피부노화의 주요 원인으로는 타입 I 콜라겐 생합성 저하 및 피부 진피세포의 증식 활성 감소를 들 수 있다. 효과적으로 피부노화를 관리하기 위해서는 안전하면서도 효능이 우수한 소재를 찾는 것이 필요하다. 이를 위해 본 연구진은 항노화소재를 스크리닝하였고, 완두콩과 밀 펩톤이 성체줄기세포의 세포증식을 증가시키는 효능을 관찰하였다. 완두콩과 밀 펩톤을 포함하는 식물성 펩톤은 다양한 크기의 펩타이드와 아미노산을 함유하고 있어 세포배양 시 첨가해 주면 영양공급원이나 growth tactor로 세포 성장과 활성을 증가시키는 것으로 알려져 있다. 본 연구에서는 인간 진피섬유아세포를 이용하여 완두콩과 밀 펩톤이 세포증식 및 콜라겐합성에 미치는 영향과 이들의 작용기전을 규명하고자 하였다. 세포증식 실험에서 완두콩과 밀 펩톤은 유의성 있게 농도 의존적으로 세포증식을 유도하였다. 또한 인간 COL1A2 프로모터 루시퍼라아제와 타입 I 프로콜라겐 생합성 실험에서 완두콩 및 밀 펩톤이 COL1A2 프로모터의 활성화를 통해 타입 I 프로콜라겐 생합성을 촉진시키고 있음을 확인하였다. TGF-${\beta}1$ 루시퍼라아제 리포터 실험과 TGF-${\beta}1$ ELISA 실험에서는 완두콩 및 밀 펩톤이 TGF-${\beta}1$ 유전자의 발현을 촉진한다는 사실을 관찰하였고, 이러한 결과를 통해 완두콩 및 밀 펩톤의 콜라겐 생합성 촉진 기전이 TGF-${\beta}$ 신호와 관련이 있음을 제시하였다. 즉 완두콩 및 밀 펩톤은 TGF-${\beta}1$의 발현촉진을 통해 콜라겐 생합성을 유도함을 유추할 수 있다. 완두콩과 밀 펩톤을 포함한 로션을 인체피부에 주 동안 도포하여 피부자극을 관찰한 결과, 어떠한 부작용도 관찰되지 않았다. 이러한 연구결과를 종합해 볼 때 완두콩 및 밀 펩톤이 피부자극이 없으며 피부주름을 개선시킬 수 있는 소재로 사용가능할 것으로 기대된다.