• ETRI Journal
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• v.32 no.2
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• pp.222-229
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• 2010

A conventional pseudorandom sequence generator creates only 1 bit of data per clock cycle. Therefore, it may cause a delay in data communications. In this paper, we propose an efficient implementation method for a pseudorandom sequence generator with parallel outputs. By virtue of the simple matrix multiplications, we derive a well-organized recursive formula and realize a pseudorandom sequence generator with multiple outputs. Experimental results show that, although the total area of the proposed scheme is 3% to 13% larger than that of the existing scheme, our parallel architecture improves the throughput by 2, 4, and 6 times compared with the existing scheme based on a single output. In addition, we apply our approach to a $2{\times}2$ multiple input/multiple output (MIMO) detector targeting the 3rd Generation Partnership Project Long Term Evolution (3GPP LTE) system. Therefore, the throughput of the MIMO detector is significantly enhanced by parallel processing of data communications.

• Journal of Microbiology and Biotechnology
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• v.27 no.5
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• pp.995-1004
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• 2017

Culture-dependent methods, such as heterotrophic plate counting (HPC), are usually applied to evaluate the bacteriological quality of hemodialysis water. However, these methods cannot detect the uncultured or viable but non-culturable (VBNC) bacteria, both of which may be quantitatively predominant throughout the hemodialysis water treatment system. Therefore, propidium monoazide (PMA)-qPCR associated with HPC was used together to profile the distribution of the total viable bacteria in such a system. Moreover, high-throughput sequencing of 16S rRNA gene amplicons was utilized to analyze the microbial community structure and diversity. The HPC results indicated that the total bacterial counts conformed to the standards, yet the bacteria amounts were abruptly enhanced after carbon filter treatment. Nevertheless, the bacterial counts detected by PMA-qPCR, with the highest levels of $2.14{\times}10^7copies/100ml$ in softener water, were much higher than the corresponding HPC results, which demonstrated the occurrence of numerous uncultured or VBNC bacteria among the entire system before reverse osmosis (RO). In addition, the microbial community structure was very different and the diversity was enhanced after the carbon filter. Although the diversity was minimized after RO treatment, pathogens such as Escherichia could still be detected in the RO effluent. In general, both the amounts of bacteria and the complexity of microbial community in the hemodialysis water treatment system revealed by molecular approaches were much higher than by traditional method. These results suggested the higher health risk potential for hemodialysis patients from the up-to-standard water. The treatment process could also be optimized, based on the results of this study.

• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.355-362
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• 2014

We have developed a fully automated high throughput drug screening (HTDS) system based on the microfluidic cell culture array to perform combinational chemotherapy. This system has 64 individually addressable cell culture chambers where the sequential combinatorial concentrations of two different drugs can be generated by two microfluidic diffusive mixers. Each diffusive mixer has two integrated micropumps connected to the media and the drug reservoirs respectively for generating the desired combination without the need for any extra equipment to perfuse the solution such as syringe pumps. The cell array is periodically exposed to the drug combination with the programmed LabVIEW system during a couple of days without extra handling after seeding the cells into the microfluidic device and also, this device does not require the continuous generation of solutions compared to the previous systems. Therefore, the total amount of drug being consumed per experiment is less than a few hundred micro liters in each reservoir. The utility of this system is demonstrated through investigating the viability of the prostate cancer PC3 cell line with the combinational treatments of curcumin and tumor necrosis factor-alpha related apoptosis inducing ligand (TRAIL). Our results suggest that the system can be used for screening and optimizing drug combination with a small amount of reagent for combinatorial chemotherapy against cancer cells.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.1
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• pp.45-50
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• 2023

In order to improve a total system throughput when a base station (BS) transmits data to user equipments (UEs), we propose a scheme to apply multiuser multiple-input multiple-output (MU-MIMO), space-time block coding (STBC), and non-orthogonal multiple access (NOMA) together. An MU-MIMO is applied to two UEs near the BS and STBC is applied to a UE far from the BS because of the difficulty of obtaining the channel information. Also NOMA is applied to differentiate the data from the near UE and the far UE. Two orthognal precoding vectors are used for the MU-MIMO UEs and it causes no interference between them. The STBC technique with the two procoding vectors are also used for the far UEs. Through performance analysis and simulation, we show that the proposed scheme has higher total system throughput than the conventional ones.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2000.10a
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• pp.71-74
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• 2000

Due to the complexity of parts flow and limited resources, FMS(Flexible Manufacturing System) develops blocking, starvation and deadlock problems, which reduce its performance. In order to minimize such problems buffers are imposed between workstations of the manufacturing lines. In this paper, we are concerned with finding the optimal buffer allocation with regard to maximizing system throughput in limited total buffer capacity situation of FMS. A grouping heuristic to solve the buffer allocation problem is proposed. Computer simulation using Arena will be experimented to show the validation of the proposed algotithm.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.30 no.3
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• pp.94-102
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• 2007

In this paper, we consider a line balancing problem in hybrid flowshops where each workstation has identical parallel machines. The number of machines in each workstation is determined in ways of satisfying pre-specified throughput rate of the system. To minimize the total number of machines in the systems, we propose five heuristic methods and one simulated annealing method. Extensive computational experiments found the superiorities of two heuristic methods and the meta-heuristic.

• Journal of the Korea Society for Simulation
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• v.9 no.2
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• pp.63-73
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• 2000

Due to the complexity of part flow and limited resources, FMS(Flexible Manufacturing System) develops blocking, starvation and deadlock problems, which reduce its performance. In order to minimize such problems buffers are imposed between workstations of the manufacturing lines. In this paper, we are concerned with finding the optimal buffer allocation with regard to maximizing system throughput in limited total buffer capacity situation of FMS. A dynamic programming algorithm to solve the buffer allocation problem is proposed. Computer simulation using Arena is experimented to show the validation of the proposed algorithm.

• ETRI Journal
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• v.37 no.3
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• pp.471-479
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• 2015

Traditional designs of cognitive radio (CR) focus on maximizing system throughput. In this paper, we study the joint overlay and underlay power allocation problem for orthogonal frequency-division multiple access-based CR. Instead of maximizing system throughput, we aim to maximize system energy efficiency (EE), measured by a "bit per Joule" metric, while maintaining the minimal rate requirement of a given CR system, under the total power constraint of a secondary user and interference constraints of primary users. The formulated energy-efficient power allocation (EEPA) problem is nonconvex; to make it solvable, we first transform the original problem into a convex optimization problem via fractional programming, and then the Lagrange dual decomposition method is used to solve the equivalent convex optimization problem. Finally, an optimal EEPA allocation scheme is proposed. Numerical results show that the proposed method can achieve better EE performance.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.5
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• pp.2063-2081
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• 2018

A resource allocation algorithm is proposed in this paper to simultaneously minimize the total system power consumption and maximize the system throughput for the downlink of multi-user multiple input multiple output-orthogonal frequency division multiplexing (MIMO-OFDM) systems. With the Lagrange dual decomposition method, we transform the original problem to its convex dual problem and prove that the duality gap between the two problems is zero, which means the optimal solution of the original problem can be obtained by solving its dual problem. Then, we use convex optimization method to solve the dual problem and utilize bisection method to obtain the optimal dual variable. The numerical results show that the proposed algorithm is superior to traditional single-objective optimization method in both the system throughput and the system energy consumption.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.1A
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• pp.18-26
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• 2009

Various relay technologies have been considered in wireless communication systems to enlarge the coverage and to enhance the system throughput. However, the coverage is limited by its modulation levels and additional time slot(s) is required for relaying. In the paper, by applying the hierarchical modulation to two-relay systems, two-hop relaying can be implemented instead of three hops, and both throughput and coverage can be enhanced. Throughout simulation analysis, the coverage extension is evaluated for different modulation levels and the total throughput is increased by up to two times.