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The Qualitative Rate Estimation of PAHs in Carbon Compounds of Particles in Vehicles Exhaust Gas (자동차 배기가스 중 입자상 탄소성분 내 PAHs의 정성적 비율 추정)

  • Kim, Jong Bum;Lee, Kyoung Bin;Kim, Jin Sik;Kim, Chang Hwan;Cha, Yong Ho;Kwon, Soon Bark;Bae, Gwi Nam;Kim, Shin-Do
    • Journal of Korean Society for Atmospheric Environment
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    • v.30 no.5
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    • pp.449-460
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    • 2014
  • Since the emergence of domestically produced automobiles in 1964, the number of automobiles in circulation in South Korea has increased constantly. With this rapidly increasing number of automobiles, automobile-induced environmental pollution has become an issue of great concern, especially with regard to air pollution. Of the carbon composites contained in automobile exhaust gas, PAHs are known to be carcinogenic and highly deleterious to humans and thus need to be urgently mitigated. To address this issue of PAHs, this study was conducted to estimate qualitative of particulate PAHs contained in carbon composites in automobile exhaust gas, by capturing all particulate matter discharged from the latter. To allow for differentiated analyses, the automobiles investigated were divided into 4 groups: gasoline vehicle, motocycle, diesel vehicle, and LPG vehicle. Samples were analyzed using two methods. First, in-depth analysis was performed on organic carbon (OC) and elemental carbon (EC) composites with analysis parameters, using the Thermal Optical Transmittance Method (NIOSH 5040). Second, for the examination of particulate PAHs, GC/MSD was used to analyze the 16 PAH species specified by the Environmental Protection Agency (EPA). The analyses yielded the findings that diesel vehicles had the highest mass concentration ($2,007{\mu}g/m^3$), followed by motocycle ($1,066{\mu}g/m^3$), LPG vehicle ($392{\mu}g/m^3$), and gasoline vehicles ($270{\mu}g/m^3$). The highest carbon concentrations in total particulate matter by vehicle weight were produced from LPG vehicle (79.8%), followed by gasoline vehicle (77.4%), motocycle (69.8%), and diesel vehicle (59.1%).

Pharmacokinetics of a new anti-HIV agent VP-0501 and development of its amino acid prodrug for improving oral bioavailability (Anti-HIV agent VP-0501의 생체이용성 향상을 위한 아미노산 프로드럭 개발 및 약물동태연구)

  • Cho, Hee-Jeong;Choi, Kyung-Ae;Sung, Ji-Min;Jeong, Sang-Min;Han, Jin-Soo;Kim, Jin-Suk;Shin, Ho-Chul
    • Korean Journal of Veterinary Research
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    • v.46 no.1
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    • pp.7-12
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    • 2006
  • We have studied pharmacokinetics of a new anti-human immunodeficiency virus (HIV) agent VP-0501 and its amino acid prodrug VP-0501AL which is designed to improve oral bioavailability. After oral administration at 100 mg/kg dose in rats (n = 4), VP-0501 was not detectable in plasma (<50 ng/ml), while after the administration of VP-0501AL, VP-0501 was quantitatively detected, at least for 8 hrs, with Cmax of ca. $2.5{\mu}g/ml$ and AUC of $8hr^{\ast}{\mu}g/ml$. When VP-0501 was intravenously administered at 50mg/kg, this compound appeared at a marginal level in plasma with AUC of $2hr^{\ast}{\mu}g/ml$, $t_{1/2}$ of 2 hr, $C_0$ of $0.7{\mu}g/ml$, and MRT of 3 hr. On the other hand, with intravenous VP-0501AL at the same dose, both the prodrug VP-0501AL and its metabolite VP-0501 appeared comparatively at higher level in the plasma: pharmacokinetic parameters of VP-0501AL including $Vd_{\beta}$, AUC, $t_{1/2,{\beta}}$, $C_0$, $CL_{tot}$, and MRT were ca. 2 L/kg, $70hr^{\ast}{\mu}g/ml$, 2 hr, $180{\mu}g/ml$, 0.7 L/hr/kg, and 1 hr, respectively. These results demonstrate that attachment of amino acid alanine to VP-0501 is an effective approach for improvement of its oral bioavailability. Therefore, VP-0501AL is expected to become a new highly bioavailable and potent anti-AIDS drug candidate/lead compound.

Screening of Traditional Herbal Medicines to Develop New Materials for Anti-aging and Anti-wrinkle in the Skin (전통 생약재에서의 항노화와 주름 개선 활성 신소재 탐색)

  • Lee Sang Eun;Son Dong Wook;Yoon Year Pill;Lim Tae Young;Cho Ja Wun;Kim Haen Su
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.2 s.51
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    • pp.147-152
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    • 2005
  • As a part of searching tot the natural components which inhibit the skin aging and wrinkle formation, the $80\%$ methanolie extracts of 121 species of traditional herbal medicines used to treat lung and skin disease were investigated for their in vitro anti-oxidative activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide radicals, and inhibitory activity against elastase. We selected 9 kinds of the traditional herbal medicines showing inhibitory activities of winkle formation. The effective concentrations of 9 candidates for anti-wrinke/skin firming activity was less than 0.1 mg/mL, and there is no toxicity to cell viability at these concentrations. Through analysis of human skin primary patch test data, the traditional herbal medicines represented non-irritant materials. We suggest that these 9 candidates with ability to help anti-wrinkle/skin firming may be useful for functional cosmetic materials.

Usefulness of the 20's and 30's Internet searching and consumer satisfaction for Internet shopping ($20\~30$대 인터넷 쇼핑몰 이용자의 정보탐색 유용성 및 소비자 만족도)

  • Kim In-Ok;Kye Sun-Ja
    • Journal of Family Resource Management and Policy Review
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    • v.9 no.2
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    • pp.111-126
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    • 2005
  • The purpose of the study was to find out some actual states qualities of consumers using of online mall users, as well as the factors that affect consumer satisfaction. A survey for this research was formed in order to find the consumer group between the ages of 20 and 30 who have experiences shopping online. From August 5th, 2002 to August 24th 2002, 424 were actually used tot this research The major results of the research were as follows. First, out of the people of the ages 20 to 30, the average age of people that actually purchase the online products was 27.7, and most were either office workers or students. Most of these people have purchased more than S products within a year, and won. Furthermore, $71.9\%$ of the payments were made using credit cards. The average days of using the Internet per week was 5.4 days, the average duration of utilization was 4 years, the average hours spent per day was 2 hours and 9 minutes, and the average time spent on searching information was 31 minutes per day. These peoples ability to put Internet to a practical use, their ability to use the information effectively, and the dangers of the Internet have received 3.66, 3.99, and 3.14 points out of the 5-point scale. In addition, the information search using the Internet received 3_44 points, and the consumer satisfaction received a fairly high score of 3.33 points. Second, the information searching factors involving the society and the Interact have showed efficiencies in people that received university education, people that purchase more than 3 products online per year, people that spend more than 100,000 won per year, and the people that make use of the Internet more often. Third, the customer satisfaction on Internet malls was greater in people that purchase more than 3 products, spend more than 100,000 won per year, make effective uses of the Internet, and Dow about the importance of the information search of the Internet. Fourth, the factors that affect customer satisfaction were the effectiveness of the Internet for searching information, the dangers of the Internet, and the hours spent on the Internet. The more uses of the Internet one makes, the less dangers one encounters, and the less one spends time on the internet, the higher ones customer satisfaction is was proven by this research.

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MPEG-21 Terminal (MPEG-21 터미널)

  • 손유미;박성준;김문철;김종남;박근수
    • Journal of Broadcast Engineering
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    • v.8 no.4
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    • pp.410-426
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    • 2003
  • MPEG-21 defines a digital item as an atomic unit lot creation, delivery and consumption in order to provide an integrated multimedia framework in networked environments. It is expected that MPEG-21 standardization makes it Possible for users to universally access user's preferred contents in their own way they want. In order to achieve this goal, MPEG-21 has standardized the specifications for the Digital Item Declaration (DID). Digital Identification (DII), Rights Expression Language (REL), Right Data Dictionary (RDD) and Digital Item Adaptation (DIA), and is standardizing the specifications for the Digital Item Processing (DIP), Persistent Association Technology (PAT) and Intellectual Property Management and Protection (IPMP) tot transparent and secured usage of multimedia. In this paper, we design an MPEG-21 terminal architecture based one the MPEG-21 standard with DID, DIA and DIP, and implement with the MPEG-21 terminal. We make a video summarization service scenario in order to validate ow proposed MPEG-21 terminal for the feasibility to of DID, DIA and DIP. Then we present a series of experimental results that digital items are processed as a specific form after adaptation fit for the characteristics of MPEG-21 terminal and are consumed with interoperability based on a PC and a PDA platform. It is believed that this paper has n important significance in the sense that we, for the first time, implement an MPEG-21 terminal which allows for a video summarization service application in an interoperable way for digital item adaptation and processing nth experimental results.

A Study of Improving Methods for The Performance of Freeway Incident Detection Algorithm (고속도로 돌발상황검지알고리즘 성능 개선기법에 관한 연구)

  • 강수구;손봉수;도철웅;이시복
    • Journal of Korean Society of Transportation
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    • v.19 no.6
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    • pp.105-118
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    • 2001
  • Incident detection rate and false alarm rate are the key measures tot estimating the performance of automatic incident detection algorithms. It is, however inherently very difficult to improve the two measures simultaneously. The main purpose of this study is to present some methods for solving the problem. For this, an incident detection algorithm has been designed in this study. The algorithm is consisted of two functions, one for detecting incident and another for detecting congestion. A logic for distinguishing non-recurrent congestion from recurrent congestion was employed in the algorithm. The new algorithm basically requires speed, flow, and occupancy data for defining incident situation, but the algorithm is able to perform this task without one of the three parameters. The performance of the algorithm has been evaluated by using the field data collected from Interstate Highway 880 in Bay Area, California. The empirical analysis results are very promising and thus, the algorithm proposed may be very useful for the analysts. This paper presents some empirical test results for the performance of California incident detection algorithm, only for the reference purpose.

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THE CORRELATION BETWEEN CRANIAL BASE SIZE, SHAPE AND HEAD POSTURE, AND THE POSITION OF MAXILLO-FACIAL STRUCTURES (두개저의 크기, 형태 및 두부자세와 악안면구조의 위치적 상관관계)

  • Hong, Yong-Seok;Yoon, Young-Jooh;Kim, Kwang-Won
    • The korean journal of orthodontics
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    • v.27 no.5 s.64
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    • pp.743-760
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    • 1997
  • This study was done to evaluate the correlations between the size, the form of the cranial base, head posture and the horizontal and vertical position of craniofacial structures. For this purpose, 100 cephalometric radiographs were taken from the sample composed of 51 male and 49 female, 12 measurement criteria and 37 reference points were established and digitized, then calculation was performed for the values of measurement variables and the horizontal and vertical position of reference points. The correlations be4ween them were analyzed statistically and mean facial diagrams were constructed and compared with the selected groups which were composed of 10 Samples each as large and small group from the measurement value. The following results were obtained: 1. The angles n-s-ba and n-s-ar as variables for the ion of cranial base correlated highly to the horizontal and vertical position of reference points in the cervical column with statistical significance($0.1\%$ level). 2. The angles n-s-ba and n-s-ar as variables for the form of cranial base correlated to the horizontal position of the reference points in the facial structure with statistical significance($1\%$ level), but not to the vertical position of them($5\%$ level). 3. The length n-s, s-ba, and n-ar as variables for the size of cranial base were correlated th the position of craniofacial structures in various ways, but in general, highly correlated to the horizontal and vertical position of midfacial structures around the teeth and alveolar area. 4. the angle NSL/CVT and NSL/OPT as postural variables tot the inclination of cranial base and cervical column were correlated to the horizontal position of the craniofacial structures with statistical significance($1\%$ level), but not to the vortical position of them($5\%$ level). 5. The angle OPT/HOR and CVT/HOR as postural variables lot the inclination of cranial base and true horizontal line were not correlated to the horizontal and vertical position of the craniofacial structures with statistical significance($5\%$ level). 6. The correlation between the measurement variables and horizontal and vortical positions of the reference poits in soft tissue were shown as similar to the related hard tissue points.

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The Effect of Inositol and Phytic Acid on Skin (이노시톨과 피틴산이 피부에 미치는 영향)

  • Zho Choon Koo;Han Chang Giu;Song Hwan
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.4 s.48
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    • pp.515-524
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    • 2004
  • Inositol and phytic acid extracted from rice bran were investigated for applying cosmetics. Skin lotions containing $0{\~}3.0\;wt\%$ inositol and $0{\~}1.50\;wt%$ phytic acid were applied respectively, to the arm skins of 45 Asian women 20'~40's for 7 weeks. Improvement on moisture was evaluated. In addition, improvements on sebum, elasticity, and wrinkle were examined after applying placebo, inositol and phytic acid-containing skin lotions tot face, respectively. For $1.0\;wt\%$ inositol, it resulted in $19\%$ increase of moisture. The wrinkle reduction and elasticity improved $12.4%\;and\;17.0\%$ on average, respec-tively. Applying $0.5\;wt\%$ phytic acid resulted in $71.6\%$ increase the moisture. Improvements on wrinkle and elasticity were $16.9%\;and\;21.9\%$ respectivelv. hpplving inositol or phytic acid regardless of dry or oily skin, resulted in sebum value recovery to that of the normal skin after 2~4 weeks. Although inositol is inferior to phytic acid in improvements of the skin, phytic acid is not suitable to sensitive skin. So, $0~0.50\;wt\%$ of phytic acid were added to $1.0\;wt\%$ inositol and similar experiments were carried out. In case of added $1.0\;wt\%$ phytic acid, moisture increased $63.8\%$ approximately. Improvements on elasticity and reduction on wrinkle were $17.2%\;and\;17.4\%,$ respectively. Both skin types were turned to normal skin type after 2 weeks. It could improve the skin condition when used inositol added phytic acid. The optimized concentration of phytic acid was $0.10\;wt\%\;with\;1.0\;wt\%$ of inositol without side effect.

Cyanide Attenuation by Granular Activated Carbon and UV-Light (활성탄 및 자외선을 이용한 시안 저감 특성 연구)

  • Lee, Hyo-Eun;Kim, Young-Jae;Park, Soo-Oh;Sung, Yoo-Hyun;Park, Chan-Oh;Lee, Hyun-Ju;Jang, Min;Lee, Young-Jae
    • Economic and Environmental Geology
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    • v.44 no.6
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    • pp.485-492
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    • 2011
  • Sorption of cyanide on granular activated carbon and attenuation of the cyanide by UV-light over a wide range of conditions such as pH and concentration were investigated through batch experiments. Cyanide uptake by activated carbon is much effective at $[CN]_{ini}$ < 2 mg/L. The sorption of cyanide on activated carbon at pH 7.0 is greater than that of pH 9.0. It is found that the ratio of CN uptake to CN in solution increases at pH 9.0 whereas at pH 7.0 the ratio decreases, suggesting that reactivity of activated carbon increases as a function of pH. The sorption of cyanide rapidly increases during the first 30 min, followed by sharp desorption until 3hr, and then the sorption increases and reaches the maximum sorption during the duration of experiments, implying that the sorption mode could be changed through conformational change during the initial stage of the cyanide uptake by activated carbon. Total amount of cyanide desorbed from the activated carbon during the period of desorption experiments is less than 1.5% of total sorbed cyanide, indicative of strong and stable sorption of cyanide on the activated carbon. The sorption with mixture of activated carbon and Ham-Baek sludge shows less effective on the removal of the cyanide. It is noted that UV-light is much effective on the removal of cyanide but also the attenuation is achieved until $[CN]_{tot}$ is up to 10 mg/L. Our findings demonstrate that both activated carbon and UV-light are very effective on the attenuation of cyanide over a wide range of environmental conditions.