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Screening of Traditional Herbal Medicines to Develop New Materials for Anti-aging and Anti-wrinkle in the Skin  

Lee Sang Eun (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Son Dong Wook (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Yoon Year Pill (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Lim Tae Young (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Cho Ja Wun (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Kim Haen Su (Institute of Food & Culture Research & Development Center for Functional Food, Pulmuone Corporation, Yeonsei University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.31, no.2, 2005 , pp. 147-152 More about this Journal
Abstract
As a part of searching tot the natural components which inhibit the skin aging and wrinkle formation, the $80\%$ methanolie extracts of 121 species of traditional herbal medicines used to treat lung and skin disease were investigated for their in vitro anti-oxidative activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide radicals, and inhibitory activity against elastase. We selected 9 kinds of the traditional herbal medicines showing inhibitory activities of winkle formation. The effective concentrations of 9 candidates for anti-wrinke/skin firming activity was less than 0.1 mg/mL, and there is no toxicity to cell viability at these concentrations. Through analysis of human skin primary patch test data, the traditional herbal medicines represented non-irritant materials. We suggest that these 9 candidates with ability to help anti-wrinkle/skin firming may be useful for functional cosmetic materials.
Keywords
anti-wrinke/anti-aging elastase inhibitory activity; traditional herbal medicines; anti-oxidative activity;
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