• Title/Summary/Keyword: TN cell

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Twisted Nematic LC Modulator for TFT Array Inspection

  • Bae, B.S.;Park, D.H.;Lee, H.K.;Lee, S.E.;Kim, S.H.;Jeong, D.H.;Rho, B.G.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.290-292
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    • 2007
  • A twisted nematic type liquid crystal electro-optic modulator (TN-LC modulator) was developed. The modulator used single polarizer and the reflection on-off ratio was maximized by optimization of twist angle and retardation of liquid crystal cell. The TNLC modulator shows better sensitivity and response time than conventional liquid crystal modulator.

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Biochemical Analysis of Baculovirus-insect Cell Interaction: I. Improved Recombinant ${\beta}-Galactosidase$ Production Using Medium Additives at AcNPV Infection of Insect Cells (Baculovirus-곤충세포 상호반응에 대한 생화학적 연구 -I. AcNPV의 곤충세포 감염시 배지 첨가물을 이용한 재조합 ${\beta}-galactosidase$ 생산 향상-)

  • Lee, Ki-Woong;Kim, Tae-Yong;Chung, In-Sik
    • Applied Biological Chemistry
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    • v.38 no.6
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    • pp.485-489
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    • 1995
  • The medium additives such as fatty acid, lipid, mannose, folic acid, $CaCl_2$ were examined to enhance recombinant ${\beta}-galactosidase\;({\beta}-gal)$ production in T-flask and air-lift bioreactor. The addition of each component. such as cholesterol, tocopherol, tricaprylin, mannose and folic acid at AcNPV infection of Tn5B1-4 cells enhanced ${\beta}-gal$ production, whereas the addition of $CaCl_2$ did not increase ${\beta}-gal$ production. The recombinant ${\beta}-gal$ production using the infection medium supplemented with a mixture of 0.34 mM cholesterol, 2.2 mM mannose and 0.045 M folic acid was enhanced 2 fold in an air-lift bioreactor, compared to the basal medium.

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Expression and Characterization of Recombinant E2 Protein of Hepatitis C Virus by Insect Cell/Baculovirus Expression System

  • Han, Bong-Kwan;Lee, Bum-Yong;Min, Mi-Kyung;Jung, Kyung-Hwan
    • Journal of Microbiology and Biotechnology
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    • v.8 no.4
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    • pp.361-368
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    • 1998
  • The E2 protein of HCV (hepatitis C virus) is thought to have a potential role in the development of subunit vaccines and diagnostics. To express it by the insect cell/baculovirus expression (Bacu) system, we constructed a recombinant Autographa californica nuclear polyhedrosis virus (AcIL3E2), determined the most appropriate expression conditions in terms of host cell line and culture medium, and characterized the expressed HCV E2 protein. A culture system using Trichoplusia ni BTI-TN5Bl-4 cells and SF 900IISFM medium expressed a relatively high level of HCV E2 protein. It was revealed that its glycosylation properties and subcellular localization were almost the same as the ones in the mammalian cell expression system previously reported, suggesting the recombinant HCV E2 protein derived from our Bacu system can be utilized for development of a subunit vaccine and diagnostics. Interestingly, HCV E2 protein was not degraded at all even at 43 h post-heat shock in the heat shock-induced necrotic cells, probably due to its integration into the microsomal membrane, indicating that heat shock can be employed to purify HCV E2 protein.

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Whitening and Antioxidant Effects of Extracts from Angelica gigas Nakai Thin Root (참당귀 세미 추출물의 미백 및 항산화 효과)

  • Lee, Sang-Hoon;Park, Jeong-Yong;Seo, Kyung Hye;Choi, Jang Nam;Lee, Yoon-Jeong;Moon, Youn-Ho;Hur, Mok;Park, Woo Tae;Huh, Yun Chan;Chang, Jae-Ki;Koo, Sung Cheol
    • Korean Journal of Plant Resources
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    • v.34 no.1
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    • pp.37-43
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    • 2021
  • Angelica gigas Nakai (AGN) is a perennial plant belonging to the family Apiaceae. Its root has been utilized as a traditional medicine especially in Korea. This study was carried out to evaluate the potential use of extracts from AGN root parts as a cosmetic material. The dried AGN roots are divided into body (B), thick root (TkR), medium root(MR) and thin root (TnR) according to their diameter before cutting into medicine. B, TkR and MR of AGN are combined and used as medicinal herbs (MH). The extracts from AGN each root part (B, TkR, MR, TnR, MH) were used to test the effect on cell viability using MTS assay and to examine inhibitory effect on melanin accumulation in B16F10 melanoma cells. All extracts (50 - 200 ㎍/mL) from the each root part did not affect the cell viability. And inhibitory effect of all root extracts (200 ㎍/mL) on melanin accumulation was 12-19%. Especially, TnR showed similar inhibitory effect on melanin accumulation to MH. In addition, DPPH and ABTS free radical scavenging activity were higher in the TnR extract compared to MH. This study showed that the TnR extract exhibit high inhibitory effect on melanin accumulation and antioxidant activity compared to MH, suggesting that TnR extract has potential as a cosmetic ingredient.

Characteristic confirm of Compensated Film Characteristics using Reactive Rod-like Mesogen in Twisted Nematic mode (TN mode에서의 Reactive Rod-like Mesogen을 이용한 보상필름의 특성 확인)

  • Jeon, Eun-Jeong;Kwon, Dong-Won;Kang, Byeong-Gyun;Lim, Young-Jin;Kim, Jong-Hoon;Seong, Hyeon-Jun;Lee, Myong-Hoon;Lee, Seung-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.271-272
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    • 2009
  • We fabricated a hybrid aligned film using reactive rod-like mesogen to reduce light leakage of twisted nematic(TN) cell in off-axis of the dark state. We proved that the fabricated compensation film has hybrid alignment by changing phase retardation according to polar angle. In this paper, we confirmed characteristics of compensation film through simulation results and found the matching factor of simulation results and experimental result. In result, the maximum pretilt angle of hybrid compensated film is $19^{\circ}$ which has phase retardation 0.1445.

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Clinical Significance of Basal-like Breast Cancer in Chinese Women in Heilongjiang Province

  • Liu, Ying;Jiang, Qiu-Ying;Xin, Tao;Cai, Li;Zhao, Chang-Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2735-2738
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    • 2012
  • Background: Our objective was to clarify the clinical and biological characteristics of basal-like breast cancer (BLBC) and non-basal-like breast cancer (TN3BKE) in Heilongjiang. Methods: We examined, by immunohistochemistry, expression of biological markers cytokeratin (CK) 5/6 and epidermal growth factor receptor (EGFR) and B cell specific moloney murine leukemia virus integration site 1( Bmi-1) in triple-negative breast cancer (TNBC). We studied the correlation between BLBC and several factors related to tumor progression, along with its prognostic value. Results: In the 229 cases of operable TNBC, BLBC was detected in 178 (77.7%) and TN3BKE- in 51 (22.2%). There was no significant difference in clinicopathological factors between them, However, BLBC was significantly associated with Bmi-1 expression (P=0.000) and shorter disease-free survival (DFS) (P = 0.045) and overall survival (OS) (P = 0.041). Conclusions: Compared with the non-basal group, patients with BLBC have a high expression of Bmi-1 and a poor prognosis.

Electrode-Optic Characteristics of Fringe-field driven Twisted Nematic Mode using a Liquid Crystal with Negative Dielectric Anisotropy (유전율 이방성이 음인 액정을 이용한 fringe-field driven Twisted Nematic 모드의 전기광학 특성)

  • Song, I.S.;Shin, S.S.;Song, S.H.;Kim, H.Y.;Rhee, J.M.;Lee, S.H.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.07b
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    • pp.1054-1057
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    • 2003
  • We have studied $90^{\circ}$ twisted nematic (TN) mode driven by fringe electric field, where two polarizers are parallel each other such that the cell shows a black state before a voltage is applied. According to the studies by computer simulation for a LC with negative dielectric anisotropy, the LC twists perpendicular to the horizontal field direction of fringe electric field and the degree of tilt angle is very low, when a voltage is applied. Therefore, the new device exhibits wide viewing angle characteristic due to in-plane switching and high transmittance since the LC director aligns parallel to the polarizer axis.

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Effect of Carbon Nanotube Concentrations on Residual DC of a Twisted Nematic Liquid Crystal Cell (탄소 나노 튜브 함량에 따른 TN 액정 셀의 잔류 DC 연구)

  • Baik, In-Su;Park, Kyung-Ah;Jeon, Sang-Youn;An, Kay-Hyeok;Lee, Seung-Hee;Lee, Young-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.297-298
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    • 2005
  • We have fabricated twisted nematic (TN) liquid crystal cells doped by carbon nanotubes (CNTs) with different CNT wt. %. With a minute amount doping, multi-walled CNTs did not perturb the liquid crystal orientations at the off- and on-state. The hysteresis studies of voltage-dependent capacitance (V-C) under the influence of electric field generated by ac and dc voltage show that the residual do, which is tightly related to image sticking problem in liquid crystal displays, is greatly reduced due to ion trapping by CNTs. Also, the V-C hysteresis shows dependency of capacitance on concentration of multi-walled CNTs.

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Evaluation of Fermentation Quality of a Tropical and Temperate Forage Crops Ensiled with Additives of Fermented Juice of Epiphytic Lactic Acid Bacteria (FJLB)

  • Yahaya, M.S.;Goto, M.;Yimiti, W.;Smerjai, B.;Kawamoto, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.7
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    • pp.942-946
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    • 2004
  • This study aimed to examine the fermentation quality of a tropical Elephant grass (Pennisetum purpuereum) and temperate Italian ryegrass (Lolium multiflorum) forages ensiled additive of fermented juice of epiphytic lactic acid bacteria (LAB) and to determine what factor affects the fermentation characteristics of the crops. In both species cell walls neutral detergent fiber (NDF) and acid detergent fiber (ADF) contents in silages were consistently decreased (p<0.05) with the addition of FJLB at ensiling more then Control treatment. The FJLB additive increased number of LAB (cfu) and lactate concentration in the silages in both species. The Control treatment without additive underwent a clostridial type of fermentation with traces of propionic, iso-butyric, n-butyric acids contents with higher (p<0.01) levels of volatile basic nitrogen (VBN %TN) and had appreciable decreased of nutrient in silages. FJLB treatment improved silage nutritive value with little contents of VBN %TN, ethanol and very small amount of dry matter (DM) and hemicellulose losses (p<0.05) between 2 to 5% and 7 to 3% respectively, in Elephant grass and Italian ryegrass species. The results in this study indicates that while among the factors affecting silage fermentation butyric type of fermentation was more pronounced in tropical elephant grass compared to the temperate Italian ryegrass, FJLB additive revealed a better silage fermentation products in both species.