• 대한전자공학회논문지SD
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• 제42권8호
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• pp.53-60
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• 2005

최근 낮은 기가비트급 광통신 집적회로의 구현에 sub-micron CMOS 공정이 적용되고 있다. 본 논문에서는 표준 0.35mm CMOS 공정을 이용하여 4채널 3.125Gb/s 차동 전치증폭기 어레이를 구현하였다. 설계한 각 채널의 전치증폭기는 차동구조로 regulated cascode (RGC) 설계 기법을 이용하였고, 액티브 인덕터를 이용한 인덕티브 피킹 기술을 이용하여 대역폭 확장을 하였다 Post-layout 시뮬레이션 결과, 각 채널 당 59.3dBW의 트랜스임피던스 이득, 0.5pF 기생 포토다이오드 캐패시턴스에 대해 2.450Hz의 -3dB 대역폭, 그리고 18.4pA/sqrt(Hz)의 평균 노이즈 전류 스펙트럼 밀도를 보였다. 전치증폭기 어레이의 공급전원은 단일전압 3.3V 이고, 전력소모는 92mw이다. 이는 4채널 RGC 전치증폭기 어레이가 저전력, 초고속 광인터컨넥트 분야에 적합함을 보여준다.

• Journal of Biomedical and Translational Research
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• 제19권4호
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• pp.110-115
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• 2018

Transient ischemic attack (TIA) indicates high risk for major stroke and is considered a medical emergency. Diffusion-weighted imaging (DWI) enables detection of acute ischemic lesions. The clinical significance of DWI positive lesions in TIA is obscure and its prevalence, clinical features are not established. Therefore, we performed a clinical, etiological and prognostic analysis through a cross-sectional analysis of 235 TIA patients, grouped according to presence of DWI lesion. Clinical features, underlying risk factors for stroke, outcome and rate of recurrence were analyzed. 3 months follow-up of modified Rankin Scales (mRS) were done with telephone survey. DWI positive lesions were present in 14.0% of patients. Etiological factors significantly associated with DWI lesions in TIA patients were male sex (p = 0.038), stroke history (p = 0.012) and atrial fibrillation (p < 0.001). Presence of at least one medium or high risk of cardioembolism from TOAST classification were not associated with lesions when excluding association to atrial fibrillation (p = 0.108). Clinical features showed no significant difference. Whether the patients had lesion-positive DWI was not related to an increase in mRS score during the hospital stay or at the 3-month follow-up after discharge. Future studies should include multi-center samples with large numbers, considering each unique medical environment. Routine acquisition of follow-up DWI for proper evaluation of the tissue-based definition of TIA should also be considered.

• 전자통신동향분석
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• 제8권1호
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• pp.69-76
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• 1993

급증하는 이동 통신 수요를 충족시키고, 통신망의 ISDN(Integrated Services Digital Network)화에 부응하기 위해 현 애널로그 방식에 디지틀 방식의 도입, 전환이 불가피하다. 이에 따라 디지틀 이동통신의 한 방식으로 QUALCOMM사에 의해 제안된 CDMA(Code Division Multiple Access) 방식에 대한 표준화 작업이 TIA(Telecommunications Industry Association)의 소위원회 TR45.5 에 의해 진행되고 있다. 본 고에서는 CDMA 방식의 표준화를 위한 미국의 TIA, CTIA(Cellular Telecommunications Industry Association) 소위원회의 구성 및 역할 등에 관해, 그리고 위 소위원회의 요구에 의해 QUALCOMM사, Ericsson Radio System사, 및 SCS Mobilecomm사 등의 3개사가 제안한 방식들을 중심으로 CDMA 기술의 현황을 소개한다.

• 한국콘텐츠학회논문지
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• 제12권4호
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• pp.358-366
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• 2012

간경화(liver cirrhosis)는 섬유조직의 증식과 재생성 결절 형성의 형태학적인 변화로 2차적으로 간내혈관의 변형 및 간기능의 저하가 나타나는 질병이며, 정맥류, 복수와 부종, 간성뇌증, 간암 등의 합병증 동반을 미연에 방지하는 것이 간경변증 진단 및 치료에 핵심이다. 일반적으로 간 컴퓨터단층영상이 간경변의 진단 및 병기를 결정하는 방법으로 사용한다. 그러므로 본 연구에서는 간경화의 자동 인식을 위하여 PCA와 TIA 알고리즘을 이용한 특징추출을 통하여 간경변의 자동 검출능력을 알아보고, 각 알고리즘간의 성능을 비교하였다. 실험은 학습영상과 테스트영상으로 구분한다. 고유영상을 생성시키기 위한 학습영상으로 정상영상이 사용되고, 테스트영상으로는 간경화영상이 사용된다. 간 CT 영상에서 간의 질병 부위를 균등하게 ROI 설정하고, $50{\times}50$ 픽셀 크기로 영상을 저장하여 실험하였다. 실험결과로 PCA는 간경화 검출율이 35%로 질병 인식으로 부적합하며, TIA 알고리즘의 AGL, TM, MU, EN는 100% 질병 인식력을 나타내어 간경화 자동 진단 인식으로 가능했다. 또한 결과를 임상에 적용하여 간경변의 컴퓨터보조진단으로 활용한다면 영상의학과 의사에게 업무 부담을 줄이고, 일차적 간경변의 스크리닝 도구로서 활용이 가능할 것이다. 그리고 TIA 알고리즘을 활용한 자동진단은 질병 진단의 전단계로서 예비판독의 정보를 제공하며 간경변의 조기 진단 및 예방이 가능다고 판단된다.

• 정보와 통신
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• 제17권8호
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• pp.83-98
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• 2000

본 논문에서는 cdma2000 1X 및 1XEV HDR의 물리계층 구조와 위의 두 시스템이 TIA/EIA-95 시스템과 비교하여 개선된 점들을 살펴보았다.cdma2000 기술은 무선 인터넷 애플리케이션과 같이 서비스 사업자의 요구에 능동적으로 대처할 수 있는 플랫포옴을 가지고 있으며 그중 하나가 바로 HDR이다. 즉, 기존의 TIA-EIA-95 또는 cdma2000 1X망에 자연스럽게 융화되며, 트래픽이 링크간 비대칭적이고 벌스티한 특성을 가지며 요구되는 지연(delay) 및 QOS가 가변적인 인터넷 패킷 데이터 서비스와 같이 새로운 기능을 추가하는 것이 용이하다. 따라서 cdma2000 1X 와 HDR은 향후 일반화될 IP 서비스를 최적화하는데 있어서도 매우 효율적인 무선접속기술이다.

• Applied Biological Chemistry
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• 제33권4호
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• pp.287-292
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• 1990

황금종 대두로 부터 8종의 Bowman-Birk형 proteinase inhibitor들을 DEAE-Sephadex A-50으로 전기영동상 단일 band로 순수하게 분리하였다. 이중 inhibitor VII cysteine함량이 17%로 높고 trypsin 및 chymotrypsin에 대해 각각 독립적인 결합부위를 가지고 있으며 상기 두 효소에 대한 저해활성도의 비(TIA/CIA)가 1.0으로 전형적인 Bowman-Birk trypsin inhibitor(BBTI)로 확인되었다. 본 inhibitor와 trypsin 및 chymotrypsin complex의 dissociation constant는 각각 $9.17{\times}10^{-9}M$과 $5.14{\times}10^{-8}M$로 매우 안정하였다. 또한 inhibitor Vll은 열에 매우 안정한 단백질로 $100^{\circ}C$, 6시간 처리에도 저해활성도 감소가 50%밖에 안되었다. 순수분리된 7종의 다른 isoinhibitor중 inhibitor III만이 TIA/CIA값이 1.2로 BBTI와 비슷하였으나 그외 inhibitor I, II, IV, V,및 VIII은 그 값이 $3{\sim}29$로 BBTI와는 성질이 다른 isoinhibitnr로 추정되었다.

• Journal of Korean Neurosurgical Society
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• 제50권4호
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• pp.322-326
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• 2011

Objective : Stenting of symptomatic intracranial stenosis has recently become an alternative treatment modality. However, urgent intracranial stenting in patients with intracranial stenosis following a transient ischemic attack (TIA) or minor stroke is open to dispute. We sought to assess the feasibility, safety, and effectiveness of urgent intracranial stenting for severe stenosis (>70%) in TIA or minor stroke patients. Methods : Between June 2009 and October 2010, stent-assisted angioplasty by using a balloon-expandable coronary stent for intracranial severe stenosis (>70%) was performed in 7 patients after TIA and 5 patients after minor stroke (14 stenotic lesions). Technical success rates, complications, angiographic findings, and clinical outcomes were retrospectively analyzed. Results : Stenting was successful in all 12 patients. The mean time from symptom onset to stenting was 2.1 days (1-8 days). Post-procedural angiography showed restoration to a normal luminal diameter in all patients. In-stent thrombosis occurred in one patient (n=1, 8.3%), and was lysed with abciximab. No device-related complications, such as perforations or dissections at the target arteries or intracranial hemorrhaging, occurred in any patient. The mortality rate was 0%. No patient had an ischemic event over the mean follow-up period of 12.5 months (range, 7-21 months), and follow-up angiography (n=7) revealed no significant in-stent restenosis (>50%). Conclusion : Urgent recanalization with stenting is feasible, safe, and effective in patients with TIA or acute minor stroke with intracranial stenosis of ${\geq}$ 70%.

• Journal of Communications and Networks
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• 제2권1호
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• pp.5-17
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• 2000

cdma2000 offers several enhancement as compared to TIA/EIA-95, although it remains fully compatible with TIA/EIA-95 systems and allows for a smooth migration from one to the other-Major new capability include:1)connectivity to GSM-MAP in addition to IP and IS-41 networks; 2) new layering with new LAC and MAC architectures for improved service multiplexing and QoS management and efficient use of radio resource ;3) new bands and band widths of operation in support of various operator need and constraints, as well as desire for a smooth and progressive migration to cdma 2000; and 4) flexible channel structure in support of multiple services with various QoS and variable transmission rates at up to 1 Mbps per channel and 2 Mbps per user. Given the phenomenal success of wireless services and desire for higher rate wireless services. improved spectrum efficiency was a major design goal in the elaboration of cdma2000. Major capacity enhancing features include; 1) turbo coding for data transmission: 2)fast forward link power control :3) forward link transmit diversity; 4) support of directive antenna transmission techniques; 5) coherent reverse link structure; and 6) enhanced access channel operation. As users increasingly rely on their cell phone at work and at home for voice and data exchange, the stand-by time and operation-time are essential parameters that can influence customer's satisfaction and service utilization. Another major goal of cdma2000 was therefore to enable manufacturers to further optimize power utilization in the terminal. Major battery life enhancing features include; 1) improved reverse link performance (i.e., reduced transmit power per information bit; 2) new common channel structure and operation ;3) quick paging channel operation; 4) reverse link gated transmission ; and 5) new MAC stated for efficient and ubiquitous idle time idle time operation. this article provides additional details on those enhancements. The intent is not to duplicate the detailed cdma2000 radio access network specification, but rather to provide some background on the new features of cdma2000 and on the qualitative improvements as compared to the TIA/EIA-95 based systems. The article is focused on the physical layer structure and associated procedures. It therefore does not cover the MAC, LAC, radio resource management [1], or any other signaling protocols in any detail. We assume some familiarity with the basic CDMA concepts used in TIA/EIA-95.

• Clinics in Shoulder and Elbow
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• 제22권1호
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• pp.29-36
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• 2019

Background: The execution of fibular allograft augmentation in unstable proximal humerus fractures (PHFs) was technically demanding. In this study, the authors evaluated the clinical and radiographic outcomes after tricortical iliac allograft (TIA) augmentation in PHFs. Methods: We retrospectively assessed 38 PHF patients treated with locking-plate fixation and TIA augmentation. Insertion of a TIA was indicated when an unstable PHF showed a large cavitary defect and poor medial column support after open reduction, regardless of the presence of medial cortical comminution in preoperative images. Radiographic imaging parameters (humeral head height, HHH; humeral neck-shaft angle, HNSA; head mediolateral offset, HMLO; and status of the union), Constant score, and range of motion were evaluated. Patients were grouped according to whether the medial column support after open reduction was poor or not (groups A and B, respectively); clinical outcomes were compared for all parameters. Results: All fractures healed radiologically (average duration to complete union, 5.8 months). At final evaluation, the average Constant score was 73 points and the mean active forward flexion was $148^{\circ}$. Based on the Paavolainen assessment method, 33 patients had good results and 5 patients showed fair results. The mean loss of reduction was 1.32 mm in HHH and 5.02% in HMLO. None of the parameters evaluated showed a statistically significant difference between the two groups (poor and not poor medial column support). Conclusions: In unstable PHFs, TIA augmentation can provide good clinical and radiological results when there are poor medial column support and a large cavitary defect after open reduction.

• 센서학회지
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• 제21권1호
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• pp.1-6
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• 2012

Using a current-mode multiple reset, a current-to-voltage(I-V) converter with a wide dynamic range was produced. The converter consists of a trans-impedance amplifier(TIA), an analog-to-digital converter(ADC), and an N-bit counter. The digital output of the I-V converter is composed of higher N bits and lower bits, obtained from the N-bit counter and the ADC, respectively. For an input current that has departed from the linear region of the TIA, the counter increases its digital output, this determines a reset current which is subtracted from the input current of the I-V converter. This current-mode reset is repeated until the input current of the TIA lies in the linear region. This I-V converter is realized using 0.35 ${\mu}m$ LSI technology. It is shown that the proposed I-V converter can increase the maximum input current by a factor of $2^N$ and widen the dynamic range by $6^N$. Additionally, the I-V converter is successfully applied to a photometric sensor.