• Title/Summary/Keyword: TCL

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Assessment of health risk associated with arsenic exposure from soil, groundwater, polished rice for setting target cleanup level nearby abandoned mines

  • Lee, Ji-Ho;Kim, Won-Il;Jeong, Eun-Jung;Yoo, Ji-Hyock;Kim, Ji-Young;Lee, Je-Bong;Im, Geon-Jae;Hong, Moo-Ki
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.1
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    • pp.38-47
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    • 2011
  • This study focused on health risk assessment via multi-routes of As exposure to establish a target cleanup level (TCL) in abandoned mines. Soil, ground water, and rice samples were collected near ten abandoned mines in November 2009. The As contaminations measured in all samples were used for determining the probabilistic health risk by Monte-Carlo simulation techniques. The human exposure to As compound was attributed to ground water ingestion. Cancer risk probability (R) via ground water and rice intake exceeded the acceptable risk range of $10^{-6}{\sim}10^{-4}$ in all selected mines. In particular, the MB mine showed the higher R value than other mines. The non-carcinogenic effects, estimated by comparing the average As exposure with corresponding reference dose were determined by hazard quotient (HQ) values, which were less than 1.0 via ground water and rice intake in SD, NS, and MB mines. This implied that the non-carcinogenic toxic effects, due to this exposure pathway had a greater possibility to occur than those in other mines. Besides, hazard index (HI) values, representing overall toxic effects by summed the HQ values were also greater than 1.0 in SD, NS, JA, and IA mines. This revealed that non-carcinogenic toxic effects were generally occurred. The As contaminants in all selected mines exceeded the TCL values for target cancer risk ($10^{-6}$) through ground water ingestion and rice intake. However, the As level in soil was greater than TCL value for target cancer risk via inadvertent soil ingestion pathway, except for KK mine. In TCL values for target hazard quotient (THQ), the As contaminants in soil did not exceed such TCL value. On the contrary, the As levels in ground water and polished rice in SD, NS, IA, and MB mines were also beyond the TCL values via ground water and rice intake. This study concluded that the health risks through ground water and rice intake were greater than those though soil inadvertent ingestion and dermal contact. In addition, it suggests that the abandoned mines to exceed the risk-based TCL values are carefully necessary to monitor for soil remediation.

Distribution and accumulation of 177Lu-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice

  • Hue, Jin Joo;Lee, Hu-Jang;Nam, Sang Yoon;Kim, Jong-Soo;Lee, Beom Jun;Yun, Young Won
    • Korean Journal of Veterinary Research
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    • v.55 no.1
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    • pp.57-60
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    • 2015
  • To investigate kinetics of free $^{177}Lu$ and $^{177}Lu$-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION), suspensions were intravenously injected into the tail vein of mice at a dose of $5{\mu}Ci$/mouse or 15 mg/kg body weight, respectively. Free $^{177}Lu$ radioactivity levels were highest in kidney followed by liver and lung 1 day post-injection. $^{177}Lu$-labeled TCL-SPION radioactivity in liver and spleen was significantly higher compared to that of other organs throughout the experimental period (p < 0.05). Radioactivity in blood, brain, and epididymis rapidly declined until 28 days. Based on these results, TCL-SPION could be a safe carrier of therapeutics.

Understanding Drug-Protein Interactions in Escherichia coli FabI and Various FabI Inhibitor Complexes

  • Lee, Han-Myoung;Singh, N. Jiten
    • Bulletin of the Korean Chemical Society
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    • v.32 no.1
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    • pp.162-168
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    • 2011
  • Many ligands have been experimentally designed and tested for their activities as inhibitors against bacterial enoyl-ACP reductase (FabI), ENR. Here the binding energies of the reported ligands with the E. coli ENR-$NAD^+$ were calculated, analyzed and compared, and their molecular dynamics (MD) simulation study was performed. IDN, ZAM and AYM ligands were calculated to have larger binding energies than TCL and IDN has the largest binding energy among the considered ligands (TCL, S54, E26, ZAM, AYM and IDN). The contribution of residues to the ligand binding energy is larger in E. coli ENR-NAD+-IDN than in E. coli ENR-$NAD^+$-TCL, while the contribution of $NAD^+$ is smaller for IDN than for TCL. The large-size ligands having considerable interactions with residues and $NAD^+$ have many effective functional groups such as aromatic $\pi$ rings, acidic hydroxyl groups, and polarizable amide carbonyl groups in common. The cation-$\pi$ interactions have large binding energies, positively charged residues strongly interact with polarisable amide carbonyl group, and the acidic phenoxyl group has strong H-bond interactions. The residues which have strong interactions with the ligands in common are Y146, Y156, M159 and K163. This study of the reported inhibitor candidates is expected to assist the design of feasible ENR inhibitors.

Studies on the Agronomic Characteristics in the Winter Primary Octaploid Triticale (추파형 Primary Octaploid Triticale의 농업형질에 따른 연구)

  • Kim, B.Y.;Ahn, W.S.;Cho, C.H.;Bae, S.H.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.26 no.2
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    • pp.174-178
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    • 1981
  • The experiment was dealt with an investigations on the agronomic potential of primary octraploid triticale in comparion with Chokwang, a major common wheat, local rye cultivar and new triticale selection Suweon #1 and Suweon #2. This octaploid triticale was originated from the cross of Jukoku #81 x Local rye cultivar. The results obtained were summarized as follows; Cold tolerance of the P-Tcl was better than those of the wheat cultivar Chokwang, triticale varieties Suweon #1 and Suweon #2, and comparable to local rye. Culm length of P-Tel was 113cm that was intermediate between the wheat and rye, and its culm thickness was thiner than the checks except the rye. Lateness of heading and maturing date of the P-Tel seemed to be over-dominant. However, flowering date after heading was 3 to 7 days earlier than the Suweon #1 and Suweon #2. Yield potential of the P-Tel was poor in comparision with the triticale cultivar Suweon #1 and Suweon #2 which was attributed to the low fertility and less number of the heads per squ are meter. If it was . improved the low fertility and less number of the valid tillers through the cross with the good secondary triticale it seemed to be an useful material for triticale breeding, expecially for improving cold tolerant winter triticale varieties in Korea.

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Evaluation of Debonding Defects in Railway Concrete Slabs Using Shear Wave Tomography (전단파 토모그래피를 활용한 철도 콘크리트 궤도 슬래브 층분리 결함 평가)

  • Lee, Jin-Wook;Kee, Seong-Hoon;Lee, Kang Seok
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.3
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    • pp.11-20
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    • 2022
  • The main purpose of this study is to investigate the applicability of the shear wave tomography technology as a non-destructive testing method to evaluate the debonding between the track concrete layer (TCL) and the hydraulically stabilized based course (HSB) of concrete slab tracks for the Korea high-speed railway system. A commercially available multi-channel shear wave measurement device (MIRA) is used to evaluate debonding defects in full-scaled mock-up test specimen that was designed and constructed according to the Rheda 200 system. A part of the mock-up specimen includes two artificial debonding defects with a length and a width of 400mm and thicknesses of 5mm and 10mm, respectively. The tomography images obtained by a MIRA on the surface of the concrete specimens are effective for visualizing the debonding defects in concrete. In this study, a simple image processing method is proposed to suppress the noisy signals reflected from the embedded items (reinforcing steel, precast sleeper, insert, etc.) in TCL, which significantly improves the readability of debonding defects in shear wave tomography images. Results show that debonding maps constructed in this study are effective for visualizing the spatial distribution and the depths of the debondiing defects in the railway concrete slab specimen.

Design of an Optical System for Iris Photographing (홍채 촬영용 광학계 설계)

  • Park, Seung-Hwan;Lee, Dong-Hee
    • Journal of Korean Ophthalmic Optics Society
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    • v.14 no.4
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    • pp.39-44
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    • 2009
  • Purpose: To design a mini optical system photographing the iris, which is used in the iridology. Methods: We designed a mini optical system photographing the iris by using the Sigma 2000 design program. Results: We designed a mini optical system photographing the iris, which is suitable in the CCD using a micro actuator for auto-focusing, of which characteristics have the TCL of 30 mm, a magnification of -0.65, about 8.0 mm distance from the 1st lens to the last lens, the max barrel diameter of 11 mm, and about 1 mm of the effective stop diameter. Also the resolution line width of this system is characterised by 92 lps/mm at the 30% MTF value criterion. Conclusions: By designing an optical system of which characteristics have the TCL of 30 mm, about 8.0 mm distance from the 1st lens to the last lens, the max barrel diameter of 11 mm, and the resolution line width of $5.4{\mu}m$ at the 30% MTF value criterion, we could miniaturize the iris photographing optical system.

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A Real Time Scan Detection System against Attacks based on Port Scanning Techniques (포트 스캐닝 기법 기반의 공격을 탐지하기 위한 실시간 스캔 탐지 시스템 구현)

  • 송중석;권용진
    • Journal of KIISE:Information Networking
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    • v.31 no.2
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    • pp.171-178
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    • 2004
  • Port scanning detection systems should rather satisfy a certain level of the requirement for system performance like a low rate of “False Positive” and “False Negative”, and requirement for convenience for users to be easy to manage the system security with detection systems. However, public domain Real Time Scan Detection Systems have high rate of false detection and have difficulty in detecting various scanning techniques. In addition, as current real time scan detection systems are based on command interface, the systems are poor at user interface and thus it is difficult to apply them to the system security management. Hence, we propose TkRTSD(Tcl/Tk Real Time Scan Detection System) that is able to detect various scan attacks based on port scanning techniques by applying a set of new filter rules, and minimize the rate of False Positive by applying proposed ABP-Rules derived from attacker's behavioral patterns. Also a GUI environment for TkRTSD is implemented by using Tcl/Tk for user's convenience of managing network security.

DYE SENSITIZED SOLAR CELLS WITH HIGH PHOTO-ENERGY CONVERSION -CONTROLL OF NANO-PARTICLE SURFACES-

  • Hayase, Shuzi
    • Proceedings of the KIEE Conference
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    • 2006.04b
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    • pp.52-56
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    • 2006
  • Some of factors affecting photo-conversion efficiency of dye sensitized solar cells (DSCs) are discussed in terms of $TiO_2$ electrodes. The first topic is on the surface modification of $TiO_2$ nano-particles, which is associated with electron traps on the surface of $TiO_2$ nano-particles. The surface is modified with dye molecules under pressurized $CO_2$ atmosphere to increase the surface coverage of $TiO_2$ nano-particles with dye molecules. This increases Jsc because of an increase in the amount of dye molecules and a decrease in the amount of trapping sites on $TiO_2$ nano-particles. In addition, the decrease in the amount of trap sites increases Voc because decreases in Voc are brought about by the recombination of $I_2$ molecules with electrons trapped on the $TiO_2$ surfaces. Selective staining for tandem cells is proposed. The second topic is on the contact between a $SnO_2$/F transparent conductive layer (TCL) and nano-particles. Polishing the TCL surfaces with silica nano-particles increases the contact, resulting in Jsc increases. The third topic is the fabrication of ion-paths in $TiO_2$ layers. Electro-spray coating of $TiO_2$ nano-particles onto TCL is shown to be effective for fabricating ion-paths in $TiO_2$ layers, which increases Jsc.

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Shoot induction and regeneration using internodal transverse thin cell layer culture in Sesamum indicum L.

  • Chattopadhyaya, Banani;Banerjee, Joydeep;Basu, Asitava;Sen, Soumitra K.;Maiti, Mrinal K.
    • Plant Biotechnology Reports
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    • v.4 no.2
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    • pp.173-178
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    • 2010
  • An efficient protocol for shoot regeneration was developed for sesame (Sesamum indicum L.) internodes using the transverse thin cell layer (tTCL) culture method. The frequency of shoot regeneration and the number of adventitious buds produced from regenerated shoots depend significantly on explant age, thickness of the tTCL sections, and the phytohormones supplemented to the culture medium. A combination of 6-benzyladenine (2.0 $mg\;l^{-1}$) and a-naphthaleneacetic acid (0.5 $mg\;l^{-1}$) was found to be the best phytohormone combination for shoot bud induction, with the maximum number of shoots obtained when the tTCL sections were 0.5-1.0 mm thick and derived from 4- to 6-week-old seedlings of sesame. Well-developed shoots were rooted on MS medium without phytohormones, and 80% of the regenerated plantlets were successfully established in soil.

A Visual Concurrent Programming Based on Extended State Transition Graph (확장 상태 전이 그래프에 기반을 둔 시각 병렬 프로그래밍)

  • Chung, Won-Ho;Hur, Hye-Jung
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.8
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    • pp.2430-2441
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    • 2000
  • A visual concurrent programming environment, called ESTGVP is designed and implemented, which is easy to understand, highly portable, and can represent parallel behaviors. For our purpose, a conventional state transition graph is extended so as to enable both of synchronous and asynchronous parallel operations. We call it extended state transition graph (ESTG). ESTGVP uses the ESTG and texts for programming, and makes it easy programming sequential and parallel behaviors. Also, it is easy to understand the control structure of a program because ESTGVP is a visual programming environment based on the graph. ESTGVP is written in Tel language and thus it is highly portable on various operating systems. It consists of three major components; edition, transformation and execution. If necessary, ESTG can be transformed into C or Tel language, and its execution is based on Tel.

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