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Acoustic Damping Swirl Injector for Reduction of Combustion Instability (연소불안정 저감을 위한 음향학적 감쇠기능성 스월 인젝터)

  • Kim, Hyun-Sung;Kim, Byung-Sun;Kim, Dong-Jun;Yoon, Young-Bin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2007.04a
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    • pp.7-12
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    • 2007
  • Swirl injector with multi-stage tangential entry was analyzed to suppress high-frequency combustion instability in Liquid Rocket Engines. In order to analyze the effect of swirl injector as an acoustic absorber, swirl injector was regarded as a quarter-wave resonator and it's damping capacity is verified in atmospheric temperature. It has a finite mode of vibration and natural frequencies which can be tuned to the natural frequencies of a model combustion chamber. When the targeted injector for each modes is located at anti-node point, the amplitude of modes was decreased. And when the injector of large diameter is mounted, the split of mode which accompanies the decrease of amplitude appeared. From the experimental data, it is proved that if the location of injector mounted is located at an anti-node position of the targeted modes with proper volume, the amplitude of modes is decreased and the split of modes occurs at anti-node point.

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Targeted Gene Delivery of the Cationic Lipid Emulsion System Containing Folate-PEG-DPPE (Folate-PEG-DPPE를 포함하는 양이온성 지질 에멀젼 시스템의 표적화 유전자 전달)

  • Kwon, Sang-Kyoo;Jeong, Kwan-Ho;Kim, Young-Jin
    • Polymer(Korea)
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    • v.33 no.3
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    • pp.213-218
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    • 2009
  • A cationic lipid emulsion containing 1,2-dioleoyl-3-trimethylammonium-propane(DOTAP), Tween80, squalene has been prepared as a gene delivery system. In order to increase the transfection efficiency of gene carrier, folate was used as the tumor-targeting ligand that was attached on PEG-DPPE. HeLa and 293 cells were used for the in vitro transfection experiment. HeLa cell is a folate-positive cell line. The mean particle sizes of polymeric lipid system and DNA/lipid complex system were 206.6 nm and 150.5 nm, respectively. The transfection efficiencies of our carriers(4:l(w:w) complex ratio)were 100 times higher than that of DOTAP only emulsion due to the targeting effect of folate.

Application of the rpoS Gene for Species-Specific Detection of Vibrio vulnificus by Real-Time PCR

  • Kim, Dong-Gyun;Ahn, Sun-Hee;Kim, Lyoung-Hwa;Park, Kee-Jai;Hong, Yong-Ki;Kong, In-Soo
    • Journal of Microbiology and Biotechnology
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    • v.18 no.11
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    • pp.1841-1847
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    • 2008
  • Vibrio vulnificus is a causative agent of serious diseases in humans, resulting from the contact of wound with seawater or consumption of raw seafood. Several studies aimed at detecting V. vulnificus have targeted vvh as a representative virulence toxin gene belonging to the bacterium. In this study, we targeted the rpoS gene, a general stress regulator, to detect V. vulnificus. PCR specificity was identified by amplification of 8 V. vulnificus templates and by the loss of a PCR product with 36 non-V. vulnificus strains. The PCR assay had the 273-bp fragment and the sensitivity of 10 pg DNA from V. vulnificus. SYBR Green I-based real-time PCR assay targeting the rpoS gene showed a melting temperature of approximately $84^{\circ}C$ for the V. vulnificus strains. The minimum level of detection by real-time PCR was 2 pg of purified genomic DNA, or $10^3$ V. vulnificus cells from pure cultured broth and $10^3$ cells in 1 g of oyster tissue homogenates. These data indicate that real-time PCR is a sensitive, species-specific, and rapid method for detecting this bacterium, using the rpoS gene in pure cultures and in infected oyster tissues.

The Characteristics of Various Deviation by Block Adjustment According to GCP Arrangement (GCP 배치에 따른 Block 조정의 오차 전파 특성)

  • Kang, Joon-Mook;Um, Dae-Yong;Kang, Young-Mi;Jeon, Kyong-Min
    • Journal of Korean Society for Geospatial Information Science
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    • v.10 no.3 s.21
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    • pp.29-40
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    • 2002
  • In photogrammetry, the accuracy is analyzed by using the coordinate of the targeted position determined by the geometric principle, thus, the reliability depends on the accuracy of the coordinate of the targeted position. Thereby, geographic surveying is essential to perform such tasks, and it requires approximately $30{\sim}50%$ of total cost and times to produce a finalized map. The main purpose of this study is to determine the configuration of the disposition of minimum datum points and their configuration, which were determined by surveying values available through using the structure of block model based on the aerotriangulation. ortho projection image was produce and digital topographic map was achieved by the optima model(CASE7). We also performed comparative analysis about the result of local datum point and the accuracy of overlapping based on the surveying results. Consequently, it is possible to analyze the unknown position accurately with the optimal model., CASE 7, which is the minimum datum points configuration required to block adjustment. Furthermore, this optimal model, which provides the minimum datum points, results costs and time saving effects compared to the previous methodology.

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AKT-targeted anti-inflammatory activity of Panax ginseng calyx ethanolic extract

  • Han, Sang Yun;Kim, Juewon;Kim, Eunji;Kim, Su Hwan;Seo, Dae Bang;Kim, Jong-Hoon;Shin, Song Seok;Cho, Jae Youl
    • Journal of Ginseng Research
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    • v.42 no.4
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    • pp.496-503
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    • 2018
  • Background: Korean ginseng (Panax ginseng) plays an anti-inflammatory role in a variety of inflammatory diseases such as gastritis, hepatitis, and colitis. However, inflammation-regulatory activity of the calyx of the P. ginseng berry has not been thoroughly evaluated. To understand whether the calyx portion of the P. ginseng berry is able to ameliorate inflammatory processes, an ethanolic extract of P. ginseng berry calyx (Pg-C-EE) was prepared, and lipopolysaccharide-activated macrophages and HEK293 cells transfected with inflammation-regulatory proteins were used to test the anti-inflammatory action of Pg-C-EE. Methods: The ginsenoside contents of Pg-C-EE were analyzed by HPLC. Suppressive activity of Pg-C-EE on NO production, inflammatory gene expression, transcriptional activation, and inflammation signaling events were examined using the Griess assay, reverse transcription-polymerization chain reaction, luciferase activity reporter gene assay, and immunoblotting analysis. Results: Pg-C-EE reduced NO production and diminished mRNA expression of inflammatory genes such as cyclooxygenase-2, inducible NO synthase, and tumor necrosis factor-${\alpha}$ in a dose-dependent manner. This extract suppressed luciferase activity induced only by nuclear factor-${\kappa}B$. Interestingly, immunoblotting analysis results demonstrated that Pg-C-EE reduced the activities of protein kinase B (AKT)1 and AKT2. Conclusion: These results suggest that Pg-C-EE may have nuclear-factor-${\kappa}B$-targeted anti-inflammatory properties through suppression of AKT. The calyx of the P. ginseng berry is an underused part of the ginseng plant, and development of calyx-derived extracts may be useful for treatment of inflammatory diseases.

Susceptibility of Pine Wood Nematode Vectors to ULV Insecticides Sprayed from an Unmanned Helicopter (무인항공기를 활용한 유인항공기용 작물보호제에 대한 소나무재선충 매개충의 약제 감수성)

  • Kim, Junheon;Nam, Sangjune;Song, Jinyoung
    • Korean journal of applied entomology
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    • v.59 no.2
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    • pp.83-91
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    • 2020
  • We assessed efficacy of spraying pesticides from an unmanned helicopter to control two insect species, Monochamus alternatus and M. saltuarius, which are vectors of pine wood nematodes. Control efficacy of thiacloprid FL (33×), acetamiprid ME (33×), and flupyradifurone SL (33×) was determined by placing caged insects in the canopy of pine trees (Pinus sp). Water-sensitive paper was used to record the spray pattern of pesticide droplets and the degree of coverage; furthermore, we investigated peripheral scattering due to spraying. The three pesticides showed > 96% control efficacy against the targeted vectors, and pesticide droplet spray patterns were similar. Peripheral scattering was observed up to 20 m in front and 10 m to the left, right, and behind the targeted area. The coverage index of all the directions at 5 and 10 m distance was 6-7 and 2, respectively.

Indoor Positioning System Using Fingerprinting Technique (Fingerprinting기법을 이용한 실내 위치측위시스템)

  • Nam, Doo-Hee;Han, Ho-Yeon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.7 no.1
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    • pp.1-9
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    • 2008
  • According to the ubiquitous trend, the needs for the context based application service have been increased. These services take on Location Based Service which is based on the current location of users. It is widely used that localization techniques use GPS or ground wave and more efficient and accurate methods have been studied. Recently, not only services which targeted outdoor but also services which targeted indoor, for example home services and facility guidance of the building come into the spotlight. In case of the outdoor positioning area, COTH (Commercial Off-The-Shelf) has been released and used but relatively it doesn't produce an outcome in the indoor positioning area. Therefore, this paper Proposes the indoor positioning technique using wireless LAN (Local Area Network) which is one of the widely used wireless communication technique. It analyzes the typical WLAN location positioning methodology has been studied and their advantage and disadvantage also suggests how to design and implement the specific WLAN positioning system. In addition, it suggests new methods that progress the accuracy of the existing systems and improve the efficient computation.

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A Fat-Tissue Mimic Phantom for Therapeutic Ultrasound

  • Kim, Mi Seon;Kim, Ju Young;Jung, Hyun Du;Kim, Jae Young;Choi, Heung Ho
    • IEIE Transactions on Smart Processing and Computing
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    • v.3 no.3
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    • pp.153-159
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    • 2014
  • As the number of treatments in the therapeutic ultrasound field targeted at fat tissue increase, the performance of the equipment should be evaluated for safety using a fat phantom. In this study, a fat phantom was fabricated using olive oil and a tissue-mimicking material (TMM) phantom. To evaluate the acoustic properties of the TMM phantom according to the changes in the olive oil, the composition ratio of a liquid mixture of olive oil with a surfactant was adjusted from 5-20% in 5% steps. The acoustic properties of the phantom were evaluated using the sound velocity, attenuation coefficient, density, and acoustic impedance. The experimental results showed that the sound velocity decreased with increasing amount of olive oil but the other acoustic properties did not change. In addition, the phantom using an olive-oil mixture with a 15% composition ratio was most similar to the acoustic characteristics of fat tissue with a sound velocity of 1477.35 m/s, an attenuation coefficient of 0.514 dB/MHz-cm, a density of $1.07g/cm^3$, and an acoustic impedance of 1.575 MRayl. These experimental results are expected contribute to the accuracy of the results using a TMM phantom and will be useful for the therapeutic ultrasound field targeted at subcutaneous fat tissue.

An Analysis on the Contents Related to Hypertension In the Television Broadcast (영상매체의 고혈압관련 기사 내용 분석)

  • Ko Il Sun;Kim Tae Wha;Kim Eui Sook;Lee Sun Mi;Lee Jung Ja
    • Journal of Korean Public Health Nursing
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    • v.18 no.1
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    • pp.90-102
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    • 2004
  • The purpose of the study was to analyze the current status of hypertension related information on the mass-media. Data were collected on the hypertension related reports in three major broadcasting centers, KBS1$\cdot$2, MBC, SBS, for 2 years, 1999-2001. Sample of the study was 134 reports. The results were as follows: 1. There were differences in frequencies by broadcasting center and programs. KBS and 9PM News were highest in proportions, $62.6\%\;and\;37.3\%$ respectively. 2. In regard to reporting time, $90\%$ were reported in the afternoon. and $62.5\%$ of those reports were in 9 PM, followed by 8PM. & 7PM. and 6AM. 3. In regard to area of the report, $35.8\%$ belonged to social section, followed by $26.1\%$ science. $15.7\%$ international. and $11.2\%$ life and health. 4. In terms of monthly distribution, December, November, and August had higher proportion of reports than other months as well as fall and winter. 5. There were higher proportion of reports containing 'treatment and management' with 'complication management' targeted to 'patients' than 'prevention' targeted to 'general population' in terms of content of the report. In summary, MBC and SBS were more focused on 'treatment and management' with KBS more focused on 'prevention'. There were more 'prevention' related reports in summer, and 'complication management' reports in the morning with 'treatment and management' reports in the afternoon.

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Modeling the potential climate change-induced impacts on future genus Rhipicephalus (Acari: Ixodidae) tick distribution in semi-arid areas of Raya Azebo district, Northern Ethiopia

  • Hadgu, Meseret;Menghistu, Habtamu Taddele;Girma, Atkilt;Abrha, Haftu;Hagos, Haftom
    • Journal of Ecology and Environment
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    • v.43 no.4
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    • pp.427-437
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    • 2019
  • Background: Climate change is believed to be continuously affecting ticks by influencing their habitat suitability. However, we attempted to model the climate change-induced impacts on future genus Rhipicephalus distribution considering the major environmental factors that would influence the tick. Therefore, 50 tick occuance points were taken to model the potential distribution using maximum entropy (MaxEnt) software and 19 climatic variables, taking into account the ability for future climatic change under representative concentration pathways (RCPs) 4.5 and 8.5, were used. Results: MaxEnt model performance was tested and found with the AUC value of 0.99 which indicates excellent goodness-of-fit and predictive accuracy. Current models predict increased temperatures, both in the mid and end terms together with possible changes of other climatic factors like precipitation which may lead to higher tick-borne disease risks associated with expansion of the range of the targeted tick distribution. Distribution maps were constructed for the current, 2050, and 2070 for the two greenhouse gas scenarios and the most dramatic scenario; RCP 8.5 produced the highest increase probable distribution range. Conclusions: The future potential distribution of the genus Rhipicephalus show potential expansion to the new areas due to the future climatic suitability increase. These results indicate that the genus population of the targeted tick could emerge in areas in which they are currently lacking; increased incidence of tick-borne diseases poses further risk which can affect cattle production and productivity, thereby affecting the livelihood of smallholding farmers. Therefore, it is recommended to implement climate change adaptation practices to minimize the impacts.