• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.3
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• pp.149-156
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• 2018

Traditional medicines (TM) in Korea, China, and Japan share most of the theories and therapeutic tools, but there are also differences due to their unique histories and cultures. Here, we aim to identify the differences in the utilization of TM theory between three countries by analyzing herb usage data in terms of the related traditional theories. Herb usage data of each country was collected from "Investigation of Korean medicine use and herbal medicine consumption survey" (Korea), "Analytical report on circulation of key Chinese medicinal materials" (China), and "Survey report on raw material crude drug usage" (Japan). Fifty five herbs with sixty features belonging to five theoretical categories (four properties, five tastes, targeting meridians, treatment strategies, and herbal parts) were selected and analyzed. Weight Sum Model (WSM) and Network-Based Group Features (NBGF) were used to compare the theoretical characteristics of TM between three countries. For the statistical evaluation, we developed and applied Herb Set Enrichment Analysis (HSEA) for WSM and NBGF results. HSEA for WSM results revealed the kidney meridian were targeted more in Korea than Japan, while the spleen meridian were targeted more in Japan than Korea. Herbs with sour taste were used more in Japan than China. HSEA for NBGF results found that NBGF including warm, neutral, sweet, and tonifying features were more dominant in Korea and than Japan, while NBGF including cold, bitter, heat-clearing features were more dominant in Japan than the others. These results suggest that TM in Korea, China, and Japan have unique aspects of practice patterns and theoretical utilization.

• The Korean Journal of Emergency Medical Services
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• v.7 no.1
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• pp.43-54
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• 2003

The purpose of this study was to evaluate the accuracy of CPR skills and the satisfaction of CPR Training targeted for college students. Also, this study made comparative study of nursing students and non-nursing students. The sample consisted of 248 students(132 nursing students, 116 non-nursing students). CPR Training was designed by two components which were a lecture and demonstration by one professor and individual practice by instructors. As tool of measurement estimation satisfaction of CPR Training questionnaires were developed based on educated contents. The accuracy of CPR skills were checked by SkillReporter CPR training manikin. Collected data were computerized and analyzed by SPSS-WIN program. The results were as follows : 1. The skills of CPR were cardiac compression 92.79 times/min, correct cardiac compression rate 90.85%, ventilation 9.93 times/min, correct ventilation rate 79.34%. 2. The mean of the accuracy of CPR skills were 2.94(SD .87). 3. When errors were analyzed, the highest item was stomach distension(51.2%) of ventilation skills and too little(70.6%) of cardiac compression skills. 4. The mean of the satisfaction of CPR training were 2.87(SD .17), the highest item of the satisfaction of CPR Training was practice. 5. We found significant statistical differences based on the accuracy and the error, non-nursing students were high in correct cardiac compression per minute(t=3.615, p=.000) and ventilation too much(t=4.292, p=.000), nursing students were high in correct ventilation rate(t=-3.885, p=.000) and cardiac compression too shallow) t=-2.842, p=.005).

• Journal of the Korea Fashion and Costume Design Association
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• v.18 no.3
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• pp.71-83
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• 2016

This study attempted to analyze trends of structural changes in the front middle part of men's underwear and get basic data for the development of men's underwear patterns. In terms of a research method, the structure and pattern of the front middle part of men's underwear were analyzed by referring to the design and description of the drawing, focusing on men's underwear which targeted to isolate penis from scrotum among the 'men's underwear' or 'functional men's underwear'-related patents. According to the study, three topics were obtained as follows: a support attached to the inside of the front middle part; inner cloth attached to the inside of the front middle part; change in the structure of the front middle panel. The aspects by the specific topic targeted to isolate penis from scrotum and prevent the scrotum from adhered to a thigh are as follows: 1) When a support is attached to the inside of the front middle part, the following three methods are proposed: Penis isolated from scrotum by a rest which is designed using the band; penis and scrotum rested in the band and in a pocket respectively; protruded rest inside the front middle part of the underwear. 2) When an inner cloth is attached to the inside of the front middle part, the following methods are designed: A pocket-type inner cloth is attached; isolation of penis hole from the scrotum pocket using a rectangular separator; U-shaped pocket designed to rest penis and scrotum is attached. 3) Regarding change in the structure of the front middle panel, the integration of penis and scrotum resting parts can be divided into two cases: Securing a space using wrinkles; keeping it voluminous using the vertical line. In this all-in-one penis and scrotum-holding type, in addition, different front panel patterns were applied.

• Nutrition Research and Practice
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• v.10 no.5
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• pp.530-536
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• 2016

BACKGROUND/OBJECTIVES: The concept of "food deserts" has been widely used in Western countries as a framework to identify areas with constrained access to fresh and nutritious foods, providing guidelines for targeted nutrition and public health programs. Unlike the vast amount of literature on food deserts in a Western context, only a few studies have addressed the concept in an East Asian context, and none of them have investigated spatial patterns of unhealthy food consumption from a South Korean perspective. SUBJECTS/METHODS: We first evaluated the applicability of food deserts in a Korean setting and identified four Korean-specific unhealthy food consumption indicators, including insufficient food consumption due to financial difficulty, limited consumption of fruits and vegetables, excessive consumption of junk food, and excessive consumption of instant noodles. The KNHANES 2008-2012 data in Seoul were analyzed with stratified sampling weights to understand the trends and basic characteristics of these eating patterns in each category. GIS analyses were then conducted for the data spatially aggregated at the sub-district level in order to create maps identifying areas of concern regarding each of these indicators and their combinations. RESULTS: Despite significant reduction in the rate of food insufficiency due to financial difficulty, the rates of excessive consumption of unhealthy foods (junk food and instant noodles) as well as limited consumption of fruits and vegetables have increased or remained high. These patterns tend to be found among relatively younger and more educated groups, regardless of income status. CONCLUSIONS: A GIS-based analysis demonstrated several hotspots as potential "food deserts" tailored to the Korean context based on the observed spatial patterns of undesirable food consumption. These findings could be used as a guide to prioritize areas for targeted intervention programs to facilitate healthy food consumption behaviors and thus improve nutrition and food-related health outcomes.

• The KIPS Transactions:PartD
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• v.8D no.2
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• pp.117-124
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• 2001

A data mining system includes various data mining functions such as aggregation, association and classification, among others. To express these data mining function, a powerful data mining query language is needed. In addition, a graphic user interface(GUI) based on the data mining query language is needed for users. In addition, processing a data mining query targeted for a data warehouse, which is the appropriate data repository for decision making, is needed. In this paper, we first build a GUI to enable users to easily define data mining queries. We then propose a data mining query processing framework that can be used to process a data mining query targeted for a data warehouse. We also implement a schema generate a data warehouse schema that is needed to build a data warehouse. Lastly, we show the implementation details of a query processor that can process queries that discover association rules.

• KIPS Transactions on Computer and Communication Systems
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• v.3 no.5
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• pp.163-172
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• 2014

The Scale Invariant Feature Transform (SIFT) has been widely used in a lot of applications for image feature matching. Such a transform allows us to strong matching ability, stability in rotation, and scaling with the variety of different scales. Recently, it has been made one of the most successful algorithms in the research areas of copy-move forgery detections. Though this transform is capable of identifying copy-move forgery, it does not widely address the possibility that counter-forensics operations may be designed and used to hide the evidence of image tampering. In this paper, we propose a targeted counter-forensics method for impeding SIFT-based copy-move forgery detection by applying a semantically admissible distortion in the processing tool. The proposed method allows the attacker to delude a similarity matching process and conceal the traces left by a modification of SIFT keypoints, while maintaining a high fidelity between the processed images and original ones under the semantic constraints. The efficiency of the proposed method is supported by several experiments on the test images with various parameter settings.

• Journal of Microbiology and Biotechnology
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• v.30 no.2
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• pp.287-295
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• 2020

The differences between luminal microbiota (LM) and mucosal microbiota (MAM) were little known, especially in duodenum. In this study, LM and MAM in colon and duodenum of mice were investigated through 16S rRNA high-throughput sequencing. The lowest bacterial diversity and evenness were observed in duodenal LM (D_LM), followed by duodenal MAM (D_MAM). Meanwhile, the bacterial diversity and evenness were obviously increased in D_MAM than these in D_LM, while no significant difference was observed between colonic MAM (C_MAM) and colonic LM (C_LM). PCoA analysis also showed that bacterial communities of LM and MAM in duodenum were completely separated, while these in colon overlapped partly. The ratio of Firmicutes to Bacteroidetes (F/B) in D_MAM was significantly higher than that in D_LM. Lactobacillus was largely enriched and was the characteristic bacteria in D_LM. The characteristic bacteria in D_MAM were Turicibacter, Parasutterella, Marvinbryantia and Bifidobacterium, while in C_LM they were Ruminiclostridium_6, Ruminiclostridium_9, Ruminococcaceae_UCG_007 and Lachnospiraceae_UCG_010, and in C_MAM they were Lachnospiraceae_NK4A136, Mucispirillum, Alistipes, Ruminiclostridium and Odoribacter. The networks showed that more interactions existed in colonic microbiota (24 nodes and 74 edges) than in duodenal microbiota (17 nodes and 29 edges). The 16S rDNA function prediction results indicated that bigger differences of function exist between LM and MAM in duodenum than these in colon. In conclusion, microbiota from intestinal luminal content and mucosa were different both in colon and in duodenum, and bacteria in colon interacted with each other much more closely than those in duodenum.

• Journal of Environmental Impact Assessment
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• v.21 no.5
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• pp.767-779
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• 2012

In case of executing surveys in marine ecosystems, the most important things are scientific selection measures of survey stations that can represent various ecosystems characteristics in subjected areas. The situations show a lot of differences that understand characteristics of marine ecosystems in targeted areas according to selection methods and positions in survey stations. Investigation ranges and station numbers in marine ecosystems are classified according to project characteristics and scales. But, currently a clear divisions or objective standards are not. Therefore, this study tried to provide selection measures of survey station in scientific and objective marine ecosystems through precise analysis among environmental impact statements of coastal development projects until now. In this study, impact scopes of marine ecosystems correspond to physical impact predictions by undertaking projects. Impact ranges were divided into three(physical impact ranges) coastal waters. In case of proposing numbers of survey stations according to this survey ranges, numbers of investigation stations due to minimum survey scopes in targeted projects applied 20~30% of all numbers in survey stations. Number of survey stations due to average investigation scopes within physical impact ranges applied 60~70% of all numbers in investigation stations. Numbers of survey stations due to maximum survey ranges within physical impact scopes applied 10~20% of all numbers in survey stations. So, improvement measures were deducted. Finally, according to prediction ranges in impact of various coastal development projects, several kinds of conclusions are suggested. And, it is thought to be able to use as fundamental database to select investigation stations in marine organisms through this study.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2883-2888
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• 2014

Background: Realgar which contains arsenic components has been used in traditional Chinese medicine (TCM) as an anticancer drug. However, neither Realgar nor its formula are soluble in water. As a result, high dose of Realgar has to be administered to achieve an effective blood medicine concentration, and this is associated with adverse side effects. The objective of the present study was to increase the solubility of a formula using hydrometallurgy technology as well as investigating its effects on in vitro and in vivo cell proliferation and apoptosis in Sarcoma-180 cell line. Materials and Methods: Antiproliferative activity of Realgar Bioleaching Solution (RBS) was evaluated by MTT assay. Further, effects of RBS on cell proliferation and apoptosis were studied using flow cytometry and transmission electron microscopy. Kunming mice were administered RBS in vivo, where arsenic specifically targeted solid tumors. Results: The results indicated that RBS extract potently inhibited the tumor growth of Sarcoma-180 cell line in a dose-dependent manner. Flow cytometry and transmission electron microscopy further indicated that RBS significantly induced cell apoptosis through the inhibition of cell cycle pathway in a dose-dependent manner. Further, on RBS administration to mice, arsenic was specifically targeted to solid tumor.s Conclusions: RBS could substitute for traditional Realgar or its formula to work as a potent tool in cancer treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4915-4918
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• 2014

Background and Aims: Advances in the treatment of cervical cancer over the last decade have predominantly involved the development of genes directed at molecular targets. Gene therapy is recognized to be a novel method for the treatment of cervical cancer. Genes can be administered into target cells via nanocarriers. This study aimed to develop systemically administrable nano-vectors. Floate (Fa) containing gene loaded nanoparticles (NPs) could target HeLa human cervical cancer cells through combination with receptors on the cells to increase the nuclear uptake of genetic materials. Methods: Fa was linked onto Poly (ethylene glycol)-b-poly (D, L-lactide) (PEG-PLA) to form Fa-PEG-PLA, and the resulting material was used to load plasmids of enhanced green fluorescence protein (pEGFP) to obtain gene loaded nanoparticles (Fa-NPs/DNA). Physical-chemical characteristics, in vitro release and cytotoxicity of Fa-NPs/DNA were evaluated. The in vitro transfection efficiency of Fa-NPs/DNA was evaluated in HeLa cells and human umbilical vein endothelial cells (HUVEC). PEG-PLA without Fa was used to load pEGFP from NPs/DNA as a control. Results: Fa-NPs/DNA has a particle size of 183 nm and a gene loading quantity of 92%. After 72h of transfection, Fa-NPs/DNA displayed over 20% higher transfection efficiency than NPs/DNA and 40% higher than naked DNA in HeLa cells. However, in HUVECs, no significant difference appeared between Fa-NPs/DNA and NPs/DNA. Conclusions: Fa-PEG-PLA NPs could function as excellent materials for gene loading. This nano-approach could be used as tumor cell targeted medicine for the treatment of cervical cancer.