• IMMUNE NETWORK
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• 제2권4호
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• pp.248-255
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• 2002

Background: TAP1 and TAP2 are two ABC transporter genes located within the class II region of the human MHC. Their protein products form a heterodimer whose function is to transport peptides from the cytoplasm into the endoplasmic reticulum. This study was performed to examine the polymorphism of TAP genes and the distribution of HLA-TAP haplotypes in the Korean population through family analysis. Methods: The subjects used in this study were 50 healthy Korean families consisting of 233 individuals. TAP1 (codons 333 and 637) and TAP2 (codons 379, 565, 577, 651, 665, and 687) typings were carried out by the PCR-restriction fragment length polymorphism (RFLP) method. HLA-DRB1 and DQB1 genotyping results from a previous study were used for HLA-TAP haplotype analysis. Results: The number (gene frequency) of TAP1 and TAP2 alleles detected were 3 for TAP1 (A 81.5%, B 17.0%, and C 1.5%) and 8 for TAP2 (A1 32.0%, A2 12.5%, B 34.0%, Bky2 6.5%, C 7.0%, D 3.0%, E 4.5%, and G 0.5%). Eleven TAP1-TAP2 haplotypes were observed with $frequency{\geq}1%$, among which 4 haplotypes (A-B, B-A1, A-Bky2, and C-E) showed weak but significant positive linkage disequilibrium (P<0.05). When DRB1-DQB1 haplotypes were extended to TAP1 and TAP2 loci, much diversification of haplotypes was observed: 19 different DRB1-DQB1 haplotypes formed 58 different haplotypes extended to TAP1 and TAP2 loci. These results add more evidence to the view that recombination hotspot is present within and around TAP gene region. Conclusion: The allele frequencies of TAP1 and TAP2 genes and the distribution of TAP1-TAP2 and HLA-TAP haplotypes were studied in Koreans based on a family study.

• 복식
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• 제58권10호
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• pp.1-20
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• 2008

The purpose of this study is to analyze the formative characteristic of modern Tap dance costume according to its origin and kinds. For this purpose, the study explored the review of literature focusing on the historical back ground of Tap dance and investigated into the kinds of modern tap dance and the formative feature of the tap dance costume. Costumes of leading tap dancers in representative performances and movies are analyzed. The results are summarized as follows: The kinds of current tap dance could be categorized as three types of Jazz Tap Dance, Rhythm & Funk Tap Dance, Irish tap Dance as their development origin. The Tap dance widely distributed through the U.S. Hollywood movie, The Jazz Tap Dance costume was composed of magnificent and luxurious design applying the high fashion of the 1930s and 1950s in the male and female costumes. The U.S. Blacks' tap dance, Rhythm & Funk Tap costume had a close relation with resistant blacks' culture, and showing the type of free dressing not bound by previous tap dance dress. The Irish Tap Dance originated from Irish folk dance displayed the tap dance embroidered costume using the Irish traditional pattern. This study systemized the characteristic of the tap dance costume by kind, and explored the dress revealed at the tap dance as a symbolic system to the cultural zone where the dance is made.

• KNOM Review
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• 제21권2호
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• pp.26-34
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• 2018

클라우드 컴퓨팅 및 서비스의 확산으로 인터넷 트래픽과 서비스 품질 향상에 대한 요구가 증가하면서 데이터 센터 내부 서버의 리소스를 보다 효율적으로 사용하는 서버 가상화와 네트워크 가상화 기술에 대한 관심이 증가하고 있다. 트래픽 모니터링을 위해 패킷을 복제하는 기존의 하드웨어 TAP (Test Access Port) 장비는 서버 가상화 환경에서 구성된 가상 데이터 경로 (datapath)에 적합하지 않기 때문에 하드웨어 TAP 장비를 소프트웨어로 구현한 Virtual TAP (vTAP)을 통해 가상 스위치에서 패킷을 복제한다. 그러나 가상 스위치에서 vTAP을 구현하면 호스트 머신의 컴퓨팅 리소스를 가상 스위치 및 가상 머신과 공유하기 때문에 성능 저하 문제가 발생한다. 이 문제를 극복하기 위해 고속 패킷 처리 기술인 eBPF (Extended Berkeley Packet Filter) 기반의 vTAP 구현 기술을 제안하고 기존 방법과 성능을 비교한다.

• 대한전자공학회논문지SD
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• 제41권11호
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• pp.61-68
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• 2004

오늘날 모든 칩들에는 보드레벨 테스트를 위한 IEEE 1149.1 TAP 컨트롤러가 설계되어 내장된다. 하지만 최근에는 보드레벨 테스트뿐만 아니라 기능적 목적을 위해서 TAP 컨트롤러가 내장되는 경우도 다수 존재한다. 따라서 이러한 IEEE 1149.1 TAP 컨트롤러 회로를 테스트하고 모니터링 할 수 있는 동시 에러 검출 (CED: Concurrent Error Detection) 테스트 기법이 개발되었다. 본 논문에서는 기존에 제안된 여러 종류의 CED 테스트 기법을 IEEE 1149.1 TAP 컨트롤러에 적용하여 최적의 면적 오버헤드를 구현하는 기법에 대해 연구한다. 중복 기법과 패리티 예측 기법, 그리고 혼합 기법을 각각 연구하였으며, 혼합기법이 IEEE 1149.1 TAP 컨트롤러를 테스트하는 데 가장 적합한 CED 기법임을 실험을 통하여 알 수 있었다. 따라서 혼합기법은 앞으로 IEEE 1149.1 TAP 컨트롤러를 테스트하는 데 널리 사용될 수 있을 것이다. 또한 본 논문에서는 기존에 제안된 기법을 더욱 향상시켜 TAP 컨트롤러를 테스트하는 데에 소요되는 면적 오버헤드를 최소화 시켰다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5213-5217
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• 2013

Transporter associated with antigen presenting (TAP) 1 and TAP2 genes are localized in the major histocompatability complex (MHC) class II region and form a heterodimer playing a key role in endogenous pathways for antigen presentation. Defects of these genes have been reported to be common in different types of cancer. Polymorphisms identified in these loci have also been investigated and reported to be associated with several autoimmune disorders, viral infections and neoplasms. In the present study, for the first time, the allele and genotype frequencies of TAP1-333, TAP2-565, TAP2-651 and TAP2-665 were determined in patients with hematological malignancies (HM) using a PCR-RFLP method and compared with the frequencies in the control group. Our results suggested an association of TAP1-333 polymorphism with multiple myeloma-MM and TAP2-565 polymorphism with chronic lymphoid leukemia-CLL. In addition, it could be concluded that the TAP2-665 GG genotype might be a risk factor for all types of hematological malignancies included in this study.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 1990년도 추계학술대회논문집; 한양대학교, 서울; 24 Nov. 1990
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• pp.113-124
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• 1990

Tap lines are small branch piping generally less than two inches in diameter. They typically branch off of header piping having a much larger diameter. An example of a common tap line is a 3/4 inch size high point vent or low point drain. Most tap lines have at least one valve near the header tap connection to provide isolation. Two valves are often required for double isolation. A light water reactor(LWR) nuclear power plant will have several hundred tap lines. These lines come in many sizes and shapes and serve numerous functions. A single process piping valve may have three different tap lines associated with it (figure 1). Table 1 delineates the different categories of tap lines. Vibration failures of tap lines are a common occurrence in all industrial plants including nuclear and fossil power plants. These types of failures constitute a significant percentage of all piping related failures. An unscheduled plant shutdown or outage resulting from the failure of a tap line decreases plant reliability and may have a detrimental effect on plant safety. Most tap line vibration failures can be avoided through the use of appropriate routing and support techniques. Standardized designs can be developed for use in a myriad of applications. These designs will not only minimize failures but will also reduce the necessary analysis and installation efforts.

• Parasites, Hosts and Diseases
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• 제43권2호
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• pp.47-50
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• 2005

A survey was carried out from August to December 2004 in Pusan, Korea to document the presence of free-living amoeba (FLA), including the genus Acanthamoeba, in both contact lens storage cases and domestic tap water. Acanthamoeba was isolated from $5(4.2\%)$ in 120 contact lens storage cases. Four house tap water samples from residents, whose contact lens storage cases had been contaminated by Acanthamoeba, were also found to be contaminated with Acanthamoeba. Therefore, the contamination rate of FLA and Acanthamoeba in domestic tap water was investigated in order to examine the role of domestic tap water in Acanthamoeba contamination of contact lens storage cases. FLA and Acanthamoeba were identified in $97(46.8\%)\;and\;16(7.7\%)$ of the 207 domestic tap water samples, respectively. There were no significant differences between the contamination rates of FLA in tap water according to the filtration plant of origin. No FLA was detected in the tap water directly supplied by the water purification plants. Water storage tanks appear to promote FLA colonization, including Acanthamoeba, in domestic tap water. This increases the risk of Acanthamoeba contamination in contact lens storage cases as well as increasing the risk of Acanthamoeba keratitis.

• Journal of Microbiology and Biotechnology
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• 제18권4호
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• pp.631-638
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• 2008

Tandem affinity purification (TAP) method combined with LC-MS/MS is the most accurate and reliable way to study the interaction of proteins or proteomics in a genome-wide scale. For the first time, we used a TAP-tag as a mutagenic tool to disrupt protein interactions at the specific site. Although lots of commonly used mutational tools exist to study functions of a gene, such as deletional mutations and site-directed mutagenesis, each method has its own demerit. To test the usefulness of a TAP-tag as a mutagenic tool, we applied a TAP-tag to RNA polymerase II, which is the key enzyme of gene expression and is controlled by hundreds of transcription factors even to transcribe a gene. Our experiment is based on the hypothesis that there will be interrupted interactions between Pol II and transcription factors owing to the TAP-tag attached at the C-terminus of each subunit of Pol II, and the abnormality caused by interrupted protein interactions can be observed by measuring a cell-cycle of each yeast strain. From ten different TAP-tagged strains, Rpb7- and Rpb12-TAP-tagged strains show severe defects in growth rate and morphology. Without a heterodimer of Rpb4/Rpb7, only the ten subunits Pol II can conduct transcription normally, and there is no previously known function of Rpb7. The observed defect of the Rpb7-TAP-tagged strain shows that Rpb7 forms a complex with other proteins or compounds and the interruption of the interaction can interfere with the normal cell cycle and morphology of the cell and nucleus. This is a novel attempt to use a TAP-tag as a proteomic tool to study protein interactions.

• 상하수도학회지
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• 제28권4호
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• pp.461-472
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• 2014

The tap water plays a critical role in our daily life by providing clean water for drinking as well as for residential use. Its importance, however, is often hidden and criticized in mass media because drinking the unprocessed tap water as a primary source of drinking water is very low comparing to other countries. This is because survey tool in Korea is often different from those in other countries so their results on the tap water cannot be directly compared without analysis on survey questionnaire. Therefore, we examplified cases showing the difference of questions of each country and discussed the reason why results of tap water intake should not be compared without analysis on the questions. Also, distrust on Arisu without rational reason is known as the first reason of distrust on the tap water. However, it was not the ultimate reason of distrust on the tap water. To verify, we designed survey questions in a tricky way that the same question was asked twice with different choices in the survey questionnaire. Most of the people who distrust Arisu without rational reason at the first question were selected different choices and significantly reduced in the second question. This proved that the ratio of distrust on the tap water is not actually the right reason and that by providing more choices, people's distrust on the tap water without rational reason can turn into more specific reasons.

• 상하수도학회지
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• 제23권6호
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• pp.753-761
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• 2009

Bottled water market is growing at a rate of 10% per year in Korea. However, bottled water exhausts ground water. Korean government proposed to provide 'bottled tap water' at a low price in 2008. This study is the estimation of 'bottled tap water' market scale using binary logit model. we calculate that 'bottled tap water' market scale is from at least 92 billion won to 154 billion won by 150, 250 won per a bottled water, respectively. This paper indicates that scale of 'bottled tap water' market is a half of 'bottled water' market in 2007. This result provides that policy-makers with available and responsible information regarding the scale of 'bottled tap water' market.