• Investigative Magnetic Resonance Imaging
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• 제24권3호
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• pp.141-153
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• 2020

Purpose: Myocardial T1 and T2 relaxation times are affected by technical factors such as cardiovascular magnetic resonance platform/vendor. We aimed to validate T1 and T2 mapping sequences using a phantom; establish reference T1, T2, and extracellular volume (ECV) measurements using two sequences at 3T in normal Koreans; and compare the protocols and evaluate the differences from previously reported measurements. Materials and Methods: Eleven healthy subjects underwent cardiac magnetic resonance imaging (MRI) using 3T MRI equipment (Verio, Siemens, Erlangen, Germany). We did phantom validation before volunteer scanning: T1 mapping with modified look locker inversion recovery (MOLLI) with 5(3)3 and 4(1)3(1)2 sequences, and T2 mapping with gradient echo (GRE) and TrueFISP sequences. We did T1 and T2 mappings on the volunteers with the same sequences. ECV was also calculated with both sequences after gadolinium enhancement. Results: The phantom study showed no significant differences from the gold standard T1 and T2 values in either sequence. Pre-contrast T1 relaxation times of the 4(1)3(1)2 protocol was 1142.27 ± 36.64 ms and of the 5(3)3 was 1266.03 ± 32.86 ms on the volunteer study. T2 relaxation times of GRE were 40.09 ± 2.45 ms and T2 relaxation times of TrueFISP were 38.20 ± 1.64 ms in each. ECV calculation was 24.42% ± 2.41% and 26.11% ± 2.39% in the 4(1)3(1)2 and 5(3)3 protocols, respectively, and showed no differences at any segment or slice between the sequences. We also calculated ECV from the pre-enhancement T1 relaxation time of MOLLI 5(3)3 and the post-enhancement T1 relaxation time of MOLLI 4(1)3(1)2, with no significant differences between the combinations. Conclusion: Using phantom-validated sequences, we reported the normal myocardial T1, T2, and ECV reference values of healthy Koreans at 3T. There were no statistically significant differences between the sequences, although it has limited statistical value due to the small number of subjects studied. ECV showed no significant differences between calculations based on various pre- and post-mapping combinations.

• 한국자기공명학회논문지
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• 제18권1호
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• pp.15-23
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• 2014

The structural properties and relaxation processes of $MCsSO_4$ (M = Na, K, or Rb) crystals were investigated by measuring the NMR spectra and spin-lattice relaxation rates $1/T_1$ of their $^{23}Na$, $^{39}K$, $^{87}Rb$, and $^{133}Cs$ nuclei. According to the NMR spectra, the $MCsSO_4$ crystals contain two crystallographically inequivalent sites each for the M and Cs ions. Further, the relaxation rates of all these nuclei do not change significantly over the investigated temperature range, indicating that no phase transitions occur in these crystals in this range. The variations in the $1/T_1$ values of the $^{23}Na$, $^{39}K$, $^{87}Rb$, and $^{133}Cs$ nuclei in these three crystals with increasing temperature are approximately proportional to $T^2$, indicating that Raman processes may be responsible for the relaxation. Therefore, for nuclear quadrupole relaxation of the $^{23}Na$, $^{39}K$, $^{87}Rb$, and $^{133}Cs$ nuclei, Raman processes with n = 2 are more effective than direct processes.

• 한국자기공명학회논문지
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• 제14권1호
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• pp.9-17
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• 2010

The water proton relaxation rates increase linearly with concentrations of contrast agents, and could be expressed as a function of the concentrations. In this paper, we have investigated MR properties of two different contrast agents, $GdCl_3$ and $CoCl_2$. Relaxivity coefficients were calculated from individual contrast agent solutions, and used for predicting relaxation rates at mixtures of two contrast agents. From the experimental results, we have discussed the feasibility of constructing water solutions with the desired relaxation times using specific mixtures of contrast agents.

• 한국식품과학회지
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• 제30권5호
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• pp.1085-1091
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• 1998

본 실험에서는 변형력 완화시험을 통하여 고기풀을 주원료로 하는 시중 게맛살과 어묵의 물성학적 성질을 조사하였다. 또한 변형력완화시험과 T.P.A.값과의 상관관계를 조사하였다. 시료의 내부구조적 변화에 의한 영향을 가능한 한 피하기 위하여 인장율 20%에서, 또한 변형속도는 2.4 mm/sec의 조건에서 실험을 실시하였다. 어묵과 맛살의 변형력완화시험결과 초기변형력의 경우 2종류의 어묵(370.4 g)과 5종류의 맛살의 평균값(436.4 g)은 유사한 값을 나타내었으나, 변형력완화시간과 점성성분은 2종류 어묵의 평균값(17256.1 sec, $1.357{\times}10^{10}$ poise)이 5종류의 맛살의 평균값(6110 sec,$0.519^{\ast}10^{10}$ poise)보다 월등히 높은 값을 나타내었다. 변형력완화시험 결과와 T.P.A.결과를 비교시 지수항의 직선식에 대한 절편값은 T.P.A.실험에서의 경도 및 껌성, 씹힘성과 높은 상관관계(r=0.93, 0.93, 0.95, p

• 한국자기학회지
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• 제4권1호
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• pp.52-55
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• 1994

HD 기체에 대하 수소 및 중수소 원자핵 스핀-격자 완화시간 $T_{1}(H)$와 $T_{1}(D)$가 측정되었다. 실험데이타는 온도 30 K < T < 313 K 및 압력 0.67 atm < P < 1.92 atm에서 측정되어졌다. 핵자기공명 주파수는 각각 수소원자핵에 대해서 358.012 MHz였고 중수소원자핵에 대해서는 54.958 MHz였다. 측정된 $T_{1}(H)$와 $T_{1}(D)$의 비로부터 분자스핀 연산자들인 $J_{z}$와 ${3J_z}^{2}-J(J+1)$에 관련된 상관시간의 비 ${\tau}_{1}/{\tau}_{2}$의 값이 얻어졌다. J = 1 상태에서의 원자핵 스핀-격자 완화시간이 온도의 함수로서 $T^{0.25}$에 비례하는 것이 관측되었다.

• Investigative Magnetic Resonance Imaging
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• 제15권1호
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• pp.48-56
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• 2011

목적 : 본 연구에서는 금 나노 입자를 통한 국소 가열과 MR 온도 영상 기법을 결합한 Theragnosis 개념에 대한 가초연구로 금 나노 입자의 특성 및 제조 조건에 따른 MR 변수의 변화를 연구하였다. 대상 및 방법 : 실험실에서 제조된 구형과 막대형 금 나노 입자를 사용하였다. 구형 입자는 합성방법과 교반속도(stirring speed: rpm)를 변수로 설정하였고, 막대형 입자눈 첨가된 구형 입자의 양을 변수로 하여 조건을 다양화하였다. 금 나노 입자를 2% 아가로즈 젤에 1:1 로 혼합하여 임상용 1.5T MRI 시스템에서 신호를 획득하였고, $T_1$과 $T_2$ 이완시간의 측정을 위해 TR과 TE를 조절하였다. 획득한 영상의 화소별 신호 강도플 이용하여 제작한 소프트웨어로 $T_1$과 $T_2$ 이완곡선을 추정하였고, 통계 분석으로 유의성을 검증하였다. 결과 : 구형 입자의 평균 $T_1$ 값은 $1.86{\pm}0.04$초, 막대형은 평균 $2.08{\pm}0.04$초로 막대형이 더 걸게 측정되었고, 반면 평균 $T_2$ 값은 구형과 막대형 각각 $57{\pm}2.4$ ms와 $35.45{\pm}0.1$ ms로 구형 나노 입자에서 더 길게 측정되었다. 결론 : 금 나노 입자의 형태적 특성 및 제조 조건에 따른 MR 영상 변수 $T_1$과 $T_2$ 이완시간의 변화를 확인하였다. 금 나노 입자를 이용한 MR 영상 연구의 수행 시 금 나노 입자의 형태와 제조 조건에 따른 적절한 TR과 TE로 최적화된 영상을 얻을 수 있을 것으로 기대된다.

• 한국자기공명학회논문지
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• 제11권1호
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• pp.1-9
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• 2007

An unequal site exchanging system induced by restricted rotation of 9-methyl group in 1,8-dichloro-9-triptycene has been studied by spin-lattice relaxation and 2D-EXSY experiments. The exchange rate obtained from relaxation studies is very well coincident to the result of line shape analysis, and the difference of the relaxation times ($T_1$) in two different sites has an important role to analyze 2D-EXSY experimental data.

• 한국자기공명학회논문지
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• 제14권1호
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• pp.18-27
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• 2010

The NMR spectrum and spin-lattice relaxation times, $T_1$, of the $^{1}H$ nuclei in $(NH_{4})_{2}Cd_{2}(SO_{4})_{3}$ single crystals were obtained. The two minima in $T_1$ in the paraelectric phase are attributed to the reorientational motions of the $NH_{4}^{+}$ groups. The $^{1}H\;T_1$ of the $(NH_{4})_{2}Cd_{2}(SO_{4})_{3}$ crystals can be described with Bloembergen- Purcell-Pound (BPP) theory. The experimental value of $T_1$ can be expressed in terms of an isotropic correlation time ${\tau}_H$ for molecular motions by using the BPP theory, and determine the role of protons in these processes.

• Food Science and Biotechnology
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• 제17권5호
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• pp.895-898
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• 2008

The mobility of water in set yogurt during fermentation was studied using nuclear magnetic resonance (NMR) relaxometry. The spin-spin relaxation was analyzed using a 2-fraction model, resulting in 2 spin-spin relaxation time constants $T_{21}$ and $T_{22}$. Both $T_{21}$ and $T_{22}$ exhibited rapid changes between 2 and 4 hr of fermentation, coinciding with the drop in pH and the rise in lactic acid bacteria count. The spin-lattice relaxation time $T_1$ increased over the fermentation period. Both $T_1$ and $T_2$ showed an increase in the mobility of water upon gel formation during fermentation. Water redistribution within the gel matrix due to casein aggregation and structure forming may be responsible for the changes in mobility.

• 한국간호교육학회지
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• 제25권4호
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• pp.414-423
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• 2019

Purpose: This study evaluates the effect of behavioral relaxation training on distress and cancer screening intention of patients with upper gastrointestinal endoscopy. Methods: The research was conducted in a non-equivalent control group posttest design. Data were collected from endoscopy subjects in B city from October to November of 2018. Fifteen minutes of behavioral relaxation training were provided to the experimental group (n=40) and traditional relaxation therapy methods were provided to the control group (n=40). Outcome measures were distress and cancer screening intention of patients with upper gastrointestinal endoscopy. Data were analyzed with a ${\chi}^2$-test, independent t-test, Fisher's exact test with SPSS/PC version 23.0. Results: The objective discomfort (t=8.81, p<.001) of the experimental group was lower than that of the control group; there were no significant differences in the subjective discomfort (t=1.73, p=.088). The cancer screening intention (t=-5.85, p<.001) of the experimental group was significantly higher than that of the control group. Conclusion: Behavioral relaxation training was effective in heightening cancer screening intention. Therefore it can be usefully applied to increase cancer screening intention.