• Biomolecules & Therapeutics
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• v.10 no.4
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• pp.303-308
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• 2002

A bioequivalence study of Shin II Cefadroxil capsule (Shin II Pharm. Co. Ltd.) to Duricef capsule(Bo Ryung Pharm. Co. Ltd.), each containing 500 mg of cefadroxil, was conducted. Twenty three healthy Korean male subjects administered each formulation at the dose of 1 capsule (500 mg as cefadroxil) in 2 $\times$ 2 cross-over study. There was a I-week washout period between the doses. Plasma concentrations of cefadroxil were monitored for a period of 8 hr after each administration by an LC/UV method. Area under the plasma concentration-time curve up to 8 hr ($AUC_t$) was calculated by a linear trapezoidal method. $C_{max}$ was compiled from the plasma drug concentration-time data. ANOVA test was conducted for logarithmically transformed $AUC_t$ and $C_{max}$ The results showed that there are no significant differences in $AUC_t$ and $C_{max}$ between the two formulations: The differences between d1e formulations in these log transformed parameters were all for less than 20% (i.e., －0.57%, 3.84% for $AUC_t$ and $C_{max}$, respectively). The 90% confidence intervals for the log transformed data were within the acceptance range of log 0.8 to log 1.25 (i.e., log 0.94~log 1.04 and log 0.95~log 1.10 for $AUC_t$ and $C_{max}$, respectively). Based on d1e bioequivalence criteria of KFDA guidelines, the two formulations of cefadroxil were concluded to be bioequivalent.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.37 no.2
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• pp.69-74
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• 2000

The bandwidth of microstrip slot antenna with T-shaped feed line was a wider than one of the conventional feeding structure. When the slot antenna with bi-directional radiator wants to radiate only one direction, the reflector must be set up seperately. But this antenna doesn't need set up reflector. And then we proposed to a new method of a directional slot radiator with a cross-shaped feedline including the reflector using 2-layers dielectric materials. It is calculated waves and electric field distribution in the time domain by using FDTD method. We also are calculated return loss, VSWR, input impedance, and radiation pattern in the frequency domain by Fourier transforming the time domain results, respectively. It was found that the bandwidth of this antenna changes as length($\I_s$) and width($\W_s$) of slot, length of the horizontal feedline($\I_d$), length of the vertical feedline($\I_u$) and offset sensitively. After optimizing the parameters of design, the maximum bandwidth was measured as 1,850MHz at the center frequency 2.5 GHz.

• Journal of applied mathematics & informatics
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• v.20 no.1_2
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• pp.445-454
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• 2006

We describe a solution to the Ornstein-Uhlenbeck equation $\frac{dI}{dt}-\frac{1}{\tau}$I(t)=cV(t) where V(t) is a constant multiple of a Gaussian white noise. Our solution is based on a discrete set of Gaussian white noise obtained by taking sample points from a sum of single frequency harmonics that have random amplitudes, random frequencies, and random phases. Hence, it is different from the solution by the standard random walk using random numbers generated by the Box-Mueller algorithm. We prove that the power of the signal has the additive property, from which we derive that the Lyapunov characteristic exponent for our solution is positive. This compares with the solution by other methods where the noise is kept to be in an error range so that its Lyapunov exponent is negative.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5449-5454
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• 2013

Background: A large variety of familiar and non-familiar lung carcinomas (LC) are caused by long term exposure to chemical carcinogens that are present in tobacco smoke. We aimed to investigate the prevalence of 5 thrombophilic germ-line mutations in patients with lung carcinomas. Materials and Methods:A total of 52 LC patients and 212 healthy controls from same population were analyzed for FV Leiden, factor V H1299R (R2), PAI-1, MTHFR C677T, MTHFR A1298C, ACE I/D, and Apo E genes and compared. Results: Overall, heterozygous and/or homozygous point mutations in FV Leiden Apo E2, PAI-1 and MTHFR C677T genes were associated with LC in the current cohort. There was no meaningful association between LC and ACE I/D gene markers. Conclusions: The current results showed that LC is related to combined thrombophilic gene mutations and individuals with homozygosity of 4G in PAI-1 and MTHFR C677T genes and heterozygosity of FV Leiden, Apo E4 genes have a germ-line risk for LC tumorigenesis.

• Proceedings of the Korean Magnestics Society Conference
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• 2002.12a
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• pp.92-93
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• 2002

The substituted lithium ferrites combine useful ferromagnetic properties with high Curie temperature ranging from 55$0^{\circ}C$ to 85$0^{\circ}C$, [1] high saturation magnetization, [2] and low microwave dielectric loss.[3] Saturation magnetization of (Z $n_{1-x}$ F $e_{x}$)A[L $i_{0.5x}$F $e_{ 2-0.5x}$]$_{B}$ $O_4$ increased with zinc concentration, followed by a decrease at x = 0.7.[4] This is attributed to a dilution of the A-site with zinc which initially causes an increase in saturation magnetization due to the dominance of the B-site. (omitted)d))d)d))

• Journal of the Korean Society for information Management
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• v.5 no.1
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• pp.53-78
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• 1988

The purpose of this study is to verify the factors determining core journals in a field based upon the results of the citation analysis of the journals in the field of Korean History(KH). In order to verify the determinant factors, dividing the articles of the KH journals into their novelty and author's seniority, the following hypotheses were established. Hypothesis 1: When a KH journal publishes more articles on prehistoric and ancient eras than others, the journal will have higher chance to be included in the core journals. Hypothesis 2: When a KH journal publishes more articles by senior researchers than others, the journal will have higher chance to be included in the core journals. To achieve the purpose, the cited articles found in the two sample journals, namely, Backsan Hakbo and Hanguksa Yongu were analysed during the past 20 years from 1962 to 1981. Applying the Hirst's Discipline Impact Factor method to the the study, Historical Science Impact Factor(HSIF) on the samples itself and the historical era dealt with in the articles and the seniority of the authors during every five-year period. Based upon thr present study to ver~fy the two hypotheses, the following conclusions have been reached. 1) Tht. most influencing sublect mattcr era or1 thix liSIF of the lo~lrual is arranged in prehistoric arid ancient, Koryo, Chosun, recent era, and the others by order of era. 2 ) Clial~g~~lg a fringe or semicore journal u~to a core j ~ u r n a l , very IISIF' 011 it> article e r a 1s grown up arrd prcllistoric a ~ ~ d ancierlt era:. are, s p c c ~ a l l ~ , incr.eased high relatively. Char~ging a core journal int:~ a fr~ngr or semicort. journal, t.very IISIF ti dropped and prel~istc~ric and ancieut taras arc, fallen sharp relatively. 3) The most irlflr~encin~ s~niority 011 the t1SII- of ihc journal I. the senior.., written or1 prehistoric and ancient eras. Above all, the senilir'b HSIF olr prehistoric anti anclent e r a s a r e most ~nfluencing the cliangi~rg of the core journal into the fringe ur bemicore. .i) flypothesis fl is no1 vcrif~ed i r t general. T l ~ e rt, lative connections bet wee^^ the senior's HSIF 011 each era and tht, ~ l ~ a l ~ g i t l g of the tort. ji1ur.tia1 arc \:er~fied in part hut r~ot in the wliole. 5) 'The reason why the 11SIF or1 prehistori~. arid ar~cic~nt e r a s is higl~er than others can be assumed becaltic the new <, xcavations a r r contit~ued actively i l l the prrsr.llt as to the relics arid remains or1 that eras. Accordingly, the HSIF' r i l l thr 11ew 3ubject matter l~ke arcl~acmlogy trends to grow up greatly. Bctween the senior's and juriior's JISIE', junior'.; is higl~er than s., nior's except ancient e r a . That reason can be assumed bccausr Iunlorb t r j to solve the ex~sting problems thr~urglr their ow11 new viewpoints and sights. So, i t should be studied whether the 11SlF on the artic1t.s of the new subject matters and viewpoirrts is influenced to the changing of the core jorlrnal or not.

• Journal of the Korean Society for Heat Treatment
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• v.9 no.3
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• pp.161-168
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• 1996

The purpose of this study is to investigate the effect of impurity level and fabrication processes on the strength, fracture toughness and fatigue resistance of 7075, 7050 and 7175 high strength aluminum forgings. It has been verified that plane strain fracture toughness and fatigue characteristics of a specially processed 7175S-T74 alloy is superior to a conventionally processed 7075-T6/T73, 7050-T74 and 7175-T74 alloys. These beneficial effects primarily arise from two view points, i.e., the effect of reducing the impurity level of iron and silicon has significantly diminished the size and volume fraction of second phase particles such as $Al_7Cu_2Fe$ and $Mg_2Si$. Futher reduction of the amount of nonequilibrium second phase particles has been observed by applying a special fabrication process.

• Kyungpook Mathematical Journal
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• v.62 no.1
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• pp.1-28
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• 2022

In this paper, we define the G-Brauer algebras $D^G_f(x)$, where G is a cyclic group, called cyclic G-Brauer algebras, as the linear span of r-signed 1-factors and the generalized m, k signed partial 1-factors is to analyse the multiplication of basis elements in the quotient $^{\rightarrow}_{I_f}^G(x,2k)$. Also, we define certain symmetric matrices $^{\rightarrow}_T_{m,k}^{[\lambda]}(x)$ whose entries are indexed by generalized m, k signed partial 1-factor. We analyse the irreducible representations of $D^G_f(x)$ by determining the quotient $^{\rightarrow}_{I_f}^G(x,2k)$ of $D^G_f(x)$ by its radical. We also find the eigenvalues and eigenspaces of $^{\rightarrow}_T_{m,k}^{[\lambda]}(x)$ for some values of m and k using the representation theory of the generalised symmetric group. The matrices $T_{m,k}^{[\lambda]}(x)$ whose entries are indexed by generalised m, k signed partial 1-factors, which helps in determining the non semisimplicity of these cyclic G-Brauer algebras $D^G_f(x)$, where G = ℤ_r.

• Journal of Acupuncture Research
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• v.20 no.5
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• pp.107-117
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• 2003

Objective: This study was examined for effects of acupuncture of Zusanli(ST36) on the facial thermography in health subjects. Methods: The voiunteers who participating in this study had taken rest for 15 mins in room temperature ($19-21^{\circ}C$) before the examination and informed them what to prohibit smoking. drinking and administration of drug for the previous day. The thermography of face was taken using Digital Infrared Thermographic Imaging (D.I.T.I.: Dorex. DTI-16UT1. U.S.A.) by time interval of 35 minutes at 15 min before and 20 min after acupuncture stimuiation. Thermal temperature of Daying(ST5). Juliao(ST3) and Quanliao(SI18) was measured and compared. Results: The results showed that acupuncture of Zusanli(ST36) significantly decreased the Absolute defference of temperature between Daying(ST5) and Juliao(ST3) (p<0.05, Data were represented meant ${\pm}$S.E.M.(n=33)). The results showed that acupuncture of Zusanli(ST36) significantly decreased the Absolute defference of temperature between Quanliao(SI18) and Juliao(ST3)(p<0.01, Data were represented mean${\pm}$S.E.M. (n=33)). But, acupuncture of Zusanli(ST36) particularly decreased the absolute defference of temperature between Daying(ST5) and Quanliao(SI18). Also. it was observed that acupuncture of ST36 decreased variety of the color tone of thermographic contour line and decreased thermal distribution. Conclusions: The results showed that acupuncture of Zusanli(ST36) significantly decreased the absolute defference of temperature of partial facial surface. Hereafter. study about if acupuncture of Zusanli(ST36) significantly decrease the absolute defference of temperature of all the areas of facial surface is requested. Also. continued study of effects of acupuncture of other meridian on the facial thermography is requested.

• Journal of Acupuncture Research
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• v.19 no.3
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• pp.88-94
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• 2002

Objective : This study was done to observe the effects on the themal changes of Hominis Placenta acupuncture therapy. The objectives are as follows; If there are remarkable local thermal changes between pre- and post- Hominis Placenta acupuncture therapy on D.I.T.I. or not. If there are those, we examine how long its changes are maintained, the adequate interval and clinical applications of therapy. Methods : To study the local thermal changes in therapy, D.I.T.I. was used. Thermal temperatures were measured pre- and post-therapy (1 hour, 1st day, 2nd day, and 7th day). The study group was divided into two groups. One was HP(Hominis Placenta) group(N=20), the other was NS(Normal Saline) group. The Hominis Placenta acupuncture was injected into 4 points (Fengmen(風門: $B_{12}$), Feishu(肺兪: $B_{13}$), Fufen(附分: $B_{41}$), Pohu(魄戶: $B_{42}$)) by 0.05ml. Results : The following results were obtained. 1. PLACENTA HOMINIS is the dried placenta of a healthy woman, used to warm the kidney for impotence, infertility, lack of lactation, and replenish Gi(氣), blood, vital essence for emaciation, hectic fever, night sweating in consumptive diseases. 2. Hominis Placenta acupuncture therapy has effects on invigoration of vital energy (補氣, 益氣), nourishing blood (養血), and tonifying the essence (補精). 3. Hominis Placenta acupuncture therapy is effective at tissue regeneration, antibody formation, increasing immunity, hormone-like effects. So, it is clinically used in osteoporosis and facial nerve paralysis. 4. There was no significant dermatothermal changes at NS group, but HP group had remarkable changes between operated and non-operated area in post-therapy 1hour. But there were not any change on 1, 2, and 7th day.