• Journal of Chest Surgery
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• v.39 no.5 s.262
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• pp.354-358
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• 2006

Background: Pulsatile pumps for extracorporeal circulation have been known to be better for tissue perfusion than non-pulsatile pumps but be detrimental to blood corpuscles. This study is intended to examine the risks and benefits of $T-PLS^{TM}$ through the comparison of clinical effects of $T-PLS^{TM}$ (pulsatile pump) and $Bio-pump^{TM}$ (non-pulsatile pump) used for coronary bypass surgery. Material and Method: The comparison was made on 40 patients who had coronary bypass using $T-PLS^{TM}\;and\;Bio-pump^{TM}$ (20 patients for each) from April 2003 to June 2005. All of the surgeries were operated on pump beating coronary artery bypass graft using cardiopulmonary extra-corporeal circulation. Risk factors before surgery and the condition during surgery and the results were compared. Result: There was no significant difference in age, gender ratio, and risk factors before surgery such as history of diabetes, hypertension, smoking, obstructive pulmonary disease, coronary infarction, and renal failure between the two groups. Surgery duration, hours of heart-lung machine operation, used shunt and grafted coronary branch were little different between the two groups. The two groups had a similar level of systolic arterial pressure, diastolic arterial pressure and mean arterial pressure, but pulse pressure was measured higher in the group with $T-PLS^{TM}\;(46{\pm}15\;mmHg\;in\;T-PLS^{TM}\;vs\;35{\pm}13\;mmHg\;in\;Bio-pump^{TM},\;p<0.05)$. The $T-PLS^{TM}$-operated patients tended to produce more urine volume during surgery, but the difference was not statistically significant $(9.7{\pm}3.9\;cc/min\;in\;T-PLS^{TM}\;vs\;8.9{\pm}3.6\;cc/min\;in\;Bio-pump^{TM},\;p=0.20)$. There was no significant difference in mean duration of respirator usage and 24-hour blood loss after surgery between the two groups. Plasma free Hb was measured lower in the group with $T-PLS^{TM}\;(24.5{\pm}21.7\;mg/dL\;in\;T-PLS^{TM}\;versus\;46.8{\pm}23.0mg/dL\;in\;Bio-pump^{TM},\;p<0.05)$. There was no significant difference in coronary infarction, arrhythmia, renal failure and morbidity rate of cerebrovascular disease. There was a case of death after surgery (death rate of 5%) in the group tested with $T-PLS^{TM}$, but the death rate was not statistically significant. Conclusion: Coronary bypass was operated with $T-PLS^{TM}$ (Pulsatile flow pump) using a heart-lung machine. There was no unexpected event caused by mechanical error during surgery, and the clinical process of the surgery was the same as the surgery for which $Bio-pump^{TM}$ was used. In addition, $T-PLS^{TM}$ used surgery was found to be less detrimental to blood corpuscles than the pulsatile flow has been known to be. Authors of this study could confirm the safety of $T-PLS^{TM}$.

• Journal of Chest Surgery
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• v.40 no.7 s.276
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• pp.512-516
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• 2007

A mechanical circulatory support system is a life-saving option for treating acute severe respiratory failure or cardiac failure. There are currently a few types of assist devices and the Twin-Pulse Life Support (T-PLS) system is a kind of pulsatile pump. We report here on three patients with severe life threatening cardiopulmonary dysfunction who had the T-PLS system used as an assist device. The indications for applying the T-PLS system were continuing respiratory or cardiac failure in spite of maximal ventilatory and inotropic support. There were two patients with acute respiratory failure due to infection and one patient with cardiac failure due to acute myocarditis. One respiratory failure patient and one cardiac failure patient survived after applying the T-PLS system for 3 days and 5 days, respectively. The T-PLS system is useful as an assist device and it should be considered before multi-organ failure occurs.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.723-724
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• 2002

Computational modeling is presented to investigate the hemodynamics of coronary circulation for the cardiac arrest model during the operation of an ECLS called T-PLS. A lumped parameter model is utilized to delineate the hemodynamics of coronary circulation. For verification of the present method, we compute the coronary circulation for normal case and compare those results with the existing data. Numerical results on the cardiac arrest model show that T-PLS can increase LAD flow significantly.

• Journal of the Korean Society of Industry Convergence
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• v.12 no.1
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• pp.27-33
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• 2009

In this paper, a computational analysis using a lumped system model is performed to investigate the hemodynamics of coronary circulation under the operation of T-PLS relevant to the cardiac arrest cases. The coronary circulation system is assumed to be comprised of three compartments: coronary arteries, coronary capillaries, and coronary veins. The effect of myocardial muscle contraction or relaxation is represented by temporal variations in the bias pressure. To verify the present method, we analyzed the coronary circulation for normal case and then compared the results with the existing data. Numerical results on the cardiac arrest model showed that T-PLS can increase LAD flow significantly.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.721-722
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• 2002

The aim of this work is to analyze changes in cerebral hemodynamics and intracranial pressure mediated by cerebral blood flow challenges in patients with acute heart arrest. Lumped parameter model with feedback mechanism is utilized to simulate the hemodynamics of brain blood flow in case 40 min T-PLS operation is applied to patients of cardiac arrest. Numerical solutions show that cerebral blood flow and perfusion pressure in patients of cardiac arrest are sharply recovered in the initial state of T-PLS operation.

• Journal of the military operations research society of Korea
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• v.35 no.2
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• pp.87-98
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• 2009

In the military logistics, the Outsourcing such as 3PL (3rd Party Logistics) and 4PL has emerged recently as an important agenda. However, when 3PL applied prematurely, side effects will occur such as the loss of combat power in wartime, the security vulnerabilities and the high cost by a small amount of military order. Recently, the developed countries such as the United States and the Britain want to compensate for these side effects. Therefore, They are developing the private-public competitive sourcing concept for the complementary partnership and the foster competition with the private sector. To apply this concept to the Korean Military, they need to be reorganized and promote the efficiency in the military logistics. Especially, the transportation sector. Therefore, this study, which is focused on the transportation sector, offers two kinds of measures to improve such as the Dual Pallet Standard (T11, T12) and the PLS(Palletized Loading System) truck system. Finally, these improvements will be analyzed by the simulation in this paper.

• Proceedings of the KIEE Conference
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• 1999.07f
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• pp.2773-2775
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• 1999

포항가속기의 선형가속기 buncher 및 prebuncher 시스템은 가속기 건설 시에 중국의 IHEP로부터 도입된 것이다. 전체적인 시스템은 완성되었으나, 그 동안 몇 가지의 문제점이 있어, 제한된 조건하에서 사용해왔다. 이와 같은 문제점을 해결하여 선형가속기 기계장치를 이용한 연구를 활성화하고 보다 나은 전자빔을 공급해주기 위하여 일부 기계장치를 포함한 모터 및 구동부, 제어부등에 대한 성능개선을 하였고 현장 시험과 설치를 완료하였다. 특히 모터는 설치가 간단하고 정밀한 제어를 할 수 있는 5선 식 5상 스텝 모터를 사용하였고, 구동부는 MOSFET을 이용한 정 전류 초핑 방식을 채택하여 크기와 발열량을 줄였다. 그리고, 제어부는 4축의 독립된 유닛이 단일의 RS485 직렬 접속에 의해서 원격으로 제어가 가능하도록 구성하였다.

• Proceedings of the KIEE Conference
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• 2000.07b
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• pp.1283-1285
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• 2000

고 주파수 스위칭 동작을 하는 DC/DC 컨버터 혹은 인버터를 효율적으로 제작하기 위하여 고주파용 펄스 변압기의 역할은 매우 중요하다. 동작주파수가 수십 혹은 수백 kHz일 경우에는 최소의 부피로 충분한 전력을 수용하면서 변압기를 설계 및 제작하기 위하여 코어 및 권선의 선정, 코어 및 권선의 손실, 변압기의 온도상승요소, 변압기의 발열, 변압기의 누설 인덕턴스, 권선 케페시턴스, 분포 케페시턴스 그리고 공진주파수 등을 고려하여 설계하고 시험 평가하여야 한다. 본 논문에서는 위의 여러가지 요소들을 고려하여 동작주파수가 100kHz인 DC/DC 컨버터 혹은 인버터를 고밀도 제작하기 위하여 고주파용 펄스변압기를 최소의 부피로 수kW 용량으로 변압기의 온도상승요소를 고려하여 설계, 제작 그리고 실험한 결과에 대하여 기술 하고자 한다.

• Journal of the Korean Applied Science and Technology
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• v.36 no.4
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• pp.1136-1142
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• 2019

The root of Paeonia lactiflora has been used in Chinese medicine. We conducted to check the comparative qualities of ethanol solvent extraction (PLE) and supercritical carbon dioxide extraction (PLS) of P. lactiflora root. PLE had higher antioxidant and polyphenol contents than PLS. But, PLS were significantly increased peroxisome proliferator-activated receptor (PPAR)-α. In addition, PLS inhibited the adipocyte differentiation of 3T3-L1 cells. When treated with the extract at a concentration of 100 ㎍/mL, the Wnt/β-catenin pathway reporter luciferase activity of HEK 293-TOP cells increased approximately by 3-folds compared to that of the untreated control group. These results indicate that P. lactiflora supercritical carbon dioxide extract may serve as a cosmeceutical for improving skin barrier function and the treatment of obesity.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2006.05a
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• pp.13-15
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• 2006

This paper describes the problem generated in PLS luminous flux measurement with integrating sphere. In RS case, we don't use the center position of the sphere but side position for flux test The difference of the lamp position makes the luminous flux difference of same light source. We confirmed the phenomenon with three other kinds of lamps and ensured the repeatability and reliability of this work at two laboratories. finally, the correction factor which should be applied for the PLS test at Side position was calculated.