• Bulletin of the Korean Chemical Society
• /
• 제28권1호
• /
• pp.77-80
• /
• 2007

As neurofilament proteins are major cytoskeletal components of neuron, abnormality of neurofilament is proposed in brain with neurodegenerative disorders such as Parkinson's disease (PD). Since oxidative stress might play a critical role in altering normal brain proteins, we investigated the oxidative modification of neurofilament-L (NF-L) induced by the reaction of cytochrome c with H2O2. When NF-L was incubated with cytochrome c and H2O2, the protein aggregation was increased in cytochrome c and H2O2 concentrationsdependent manner. Radical scavengers, azide, formate and N-acetyl cysteine, prevented the aggregation of NFL induced by the cytochrome c/H2O2 system. The formations of carbonyl group and dityrosine were obtained in cytochrome c/H2O2-mediated NF-L aggregates. Iron specific chelator, desferoxamine, prevented the cytochrome c/H2O2 system-mediated NF-L aggregation. These results suggest that the cytochrome c/H2O2 system may be related to abnormal aggregation of NF-L which may be involved in the pathogenesis of PD and related disorders.

• 한국정보과학회:학술대회논문집
• /
• 한국정보과학회 2002년도 가을 학술발표논문집 Vol.29 No.2 (2)
• /
• pp.76-78
• /
• 2002

내장형 시스템의 개발에 있어서 자원의 효율적인 활용과 정확한 설계를 위해 SystemC를 이용한 통합설계 방식이 많이 사용되고 있다. 하지만 시스템이 점점 복잡해 지면서 단순한 언어차원에서의 개발 뿐 아니라 개발 이전에 시스템의 정확성을 검증해야 할 필요성이 대두되었다. 이를 위해 정형기법 및 테스팅과 같은 방법을 사용하게 되었다. 본 논문에서는 SystemC로부터 정형기법 도구인 VIS의 입력 언어인 BLIF-MV로 자동 변환하는 알고리즘을 제시하고, SystemC 코드로부터의 자동 검증 방법을 제안하고자 한다.

• 한국정보과학회:학술대회논문집
• /
• 한국정보과학회 2003년도 봄 학술발표논문집 Vol.30 No.1 (A)
• /
• pp.37-39
• /
• 2003

내장형 시스템의 개발에 있어서 자원의 효율적인 활용과 정확한 설계를 위해 SystemC를 이용한 통합설계 방식이 많이 사용되고 있다. 하지만 시스템이 점점 복잡해지면서 단순한 언어차원에서의 개발 뿐 아니라 개발 이전에 시스템의 정확성을 검증해야 할 필요성이 대두되었다. 이를 위해 정형기법 및 테스팅과 같은 방법을 사용하게 되었다. 본 논문에서는 SystemC로부터 정형기법 도구인 VIS의 입력 언어인 BLIF-MV로 자동 변환하는 알고리즘을 제시하고, SystemC 코드의 자동 검증 방법을 제시하고 실제 시스템에 적용해 보았다.

• Preventive Nutrition and Food Science
• /
• 제9권1호
• /
• pp.53-57
• /
• 2004

The purpose of this study was to investigate the effects of green tea catechin on mixed function oxidase system (MFO), lipofuscin contents, carbonyl value, oxidative damage and the antioxidative defense system in lung of microwave exposed rats. Experimental groups were divided to normal group and microwave exposed group. The microwave exposed groups were subdivided into three groups: catechin free diet (MW-0C) group, 0.25% catechin (MW-0.25C) group and 0.5 ％ catechin (MW-0.5C) group according to the levels of dietary catechin supplementation. The rats were irradiated with microwave at frequency of 2.45 GHz for 15 min. Experimental animals were sacrificed at 6th day after microwave irradiation. The contents of cytochrome P$_{450}$ contents in MW-0C group was increased to 95% , compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 16% and 31%, respectively, compared with MW-0C group. The activity of NADPH-cytochrome P$_{450}$ reductase in MW-0C group was increased to 44%, compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 12% and 17％, respectively, compared with MW-0C group. The activity of superoxide dismutase (SOD) in MW-0C group was decreased to 21 ％, compared with normal group. MW-0.25C and MW-0.5C group were significantly (p < 0.05) increased, compared with MW-0C group. The activity of glutathione peroxidase (GSHpx) in MW-0C group was significantly decreased, compared with normal group. MW-0.25C and MW-0.5C groups were recovered to the level of normal group. The thiobarbituric acid reactive substances (TBARS) content in MW-0C group was increased to 34 ％, compared with normal group. Catechin supplementation groups were maintained the level of normal group. The levels of caybonyl value in MW-0C group was increased to 21 ％, compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 14% and 12%, respectively, compared with MW-0C group. The lipofuscin contents in MW-0C group were increased to 23.4 ％, compared with normal group. That of MW-0.5C group was significantly reduced, compared with MW-0C group. In conclusion, MFO system was activated and the formation of oxidized protein, lipofuscin was increased and antioxidative defense system was weakened of lung tissue in microwave exposed rats, thus oxidative damage was increased. But it was rapidly recovered to normal level by green tea catechin supplementation.n.

• 한국의류학회지
• /
• 제36권8호
• /
• pp.860-874
• /
• 2012

This study provides size information on current imported medical compression stockings in Korea. A total 20 brands from 6 countries imported and sold in the Korean on-off line markets were selected for this study and the sizing system of medical compression stockings was researched. The results of this study were as follows: there were size differences among different USA brands according to product type or compression class of medical compression stockings. To establish the sizing system for medical stockings of the German brands, the basic body measurements standard was set as cA, cY, cB, cB, cC, cD, cE, cF, cG, cH, cT, lD, lG, and lT. Italian brands developed the sizing system for medical compression stockings by compression class. In the Swiss brands, size types were sub-divided as 'Normal', 'Plus', 'Short', and 'Long'. The sizing 1 were confined within very narrow limits. There were differences of the basic body measurements between Taiwan brands. The results of the comparison of the size range of the imported brands with Size Korea (KATS, 2010) by two-way size distribution shows that the sizing systems of the imported brands were unsuitable for Koreans. To enhance the suitability of the sizing system for medical compression stockings, a new sizing system for Korean adult males and females needs to be established.

• KSBB Journal
• /
• 제15권1호
• /
• pp.55-59
• /
• 2000

생난황으로부터 시알산 함유 올리고당을 직접 생산하기 위한 biphasic system(water-immiscible hexane system)의 최적 조건을 조사하였다. Biphasic system I은 II보다 생산수율이 높았으며, 온도, 함수율 및 반응 시간의 최적조건은 각각 $30^{\circ}C$, 20%, 12시간이었다. Biphasic system I 에서, 난황을 가수분해하기 위한 3종류의 효소(protease A, corolase 7089, neutrase 0.5L)의 활성은 함수율과 온도에 강하게 영향을 받았으나, biphasic system II에서는 온도($30^{\circ}C$와 $50^{\circ}C$)의 영향을 거의 받지 않았다. 두 종류의 biphasic system에서 반응시간 12시간까지는 시알산 함유 올리고당의 생산량이 증가되었으나, 15시간 이후에는 거의 증가하지 않았다.

• 한국ITS학회:학술대회논문집
• /
• 한국ITS학회 2003년도 제2회 정기총회 및 추계학술대회
• /
• pp.48-51
• /
• 2003

• 생물환경조절학회지
• /
• 제28권2호
• /
• pp.117-125
• /
• 2019

본 연구는 기존에 사용하여 왔고, 최근에 온습도의 정확도를 검증하였던 강제 흡출식 복사선 차폐장치(Aspirated Radiation Shield; ARS)와 모 기업(A 회사)에서 개발한 시스템으로 측정한 온습도를 비교하여 성능을 검토한 후, 시스템의 성능을 개선할 목적으로 수행되었다. 그 결과를 요약하면 다음과 같다. 딸기의 무성도가 두 계측시스템에 영향을 미친 경우를 제외하면, 전체적으로 볼 때 플레이트 2개의 시스템이 1개보다 복사선 차폐효과가 미미하지만 좋은 것으로 나타났다. 그리고 A회사의 시스템과 ARS장치로 측정한 최고온도의 전체적인 범위는 각각 $20.5{\sim}53.3^{\circ}C$ 및 $17.8{\sim}44.1^{\circ}C$정도로써 A사 제품이 $2.7{\sim}9.2^{\circ}C$정도 높게 나타났고, 일별 최대 편차는 $12.2^{\circ}C$ 정도였다. 평균온도의 경우, 두 기관의 전체적인 범위는 각각 $12.4{\sim}38.6^{\circ}C$ 및 $11.8{\sim}32.7^{\circ}C$정도로써 A사 시스템이 $0.6{\sim}5.9^{\circ}C$정도 높게 나타났고, 일별 최대 편차는 $6.7^{\circ}C$정도였다. 최저온도의 경우도 각각 $4.2{\sim}28.6^{\circ}C$ 및 $2.9{\sim}26.4^{\circ}C$정도로써 A사 제품이 $1.3{\sim}2.2^{\circ}C$정도 높게 나타났고, 일별 최대 편차는 $2.9^{\circ}C$정도로써 두 기관의 장치로 측정한 온도에 편차가 있는 것으로 나타났다. 또한 상대습도의 경우, A회사와 ARS장치로 측정한 평균상대습도의 전체적인 범위는 각각 52.9~93.3% 및 55.3~96.5%정도로써 A회사의 시스템이 ARS장치보다 2.4~3.2%정도 낮게 나타나는 경향을 보였다. 그러나 일별로 비교하여 보면, 최대 18.0%정도 A회사의 시스템이 낮게 나타나는 날도 있었다. 결국 상대습도도 온도와 마찬가지로 미미하긴 하지만 두 기관의 장치로 측정한 온도에 편차가 있는 것으로 나타났다.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2003년도 하계학술대회 논문집 Vol.4 No.2
• /
• pp.892-895
• /
• 2003

This paper describes on RIE(Reactive Ion Etching) characteristics of 3C-SiC(Silicon Carbide) grown on Si(100) wafers. During RIE of 3C-SiC films in this work, $CHF_3$ gas is used to form of polymer as a side wall for excellent anisotropy etching. From this process, etch rates are obtained a $60{\sim}980{\AA}/min$ by various conditions such as $CHF_3$ gas flux, $O_2$ addition ratio, RF power and electrode distance. Also, approximately $40^{\circ}$ mesa structures are successfully formed at 100 mTorr $CHF_3$ gas flow ratio, 200 W RF power and 30 mm electrode distance. Moreover, vertical side wall is fabricated by anisotropy etching with 50% $O_2$ addition ratio and 25 mm electrode distance. Therefore, RIE of 3C-SiC films using $CHF_3$ could be applicable as fabrication process technology for high-temperature 3C-SiC MEMS applications.

• JSTS:Journal of Semiconductor Technology and Science
• /
• 제4권2호
• /
• pp.88-93
• /
• 2004

We, for the first time, present novel test patterns and conclusive on-chip data indicating that the variation of coupling capacitance, ${\Delta}C_C$ by crosstalk can be larger than static coupling capacitance, $C_C$. The test chip is fabricated using a generic 150 nm CMOS technology with 7 level metallization. It is also shown that ${\Delta}C_C$ is strongly dependent on the phase of aggressive lines. For antiphase crosstalk ${\Delta}C_C$ is always larger than $C_C$ while for in-phase crosstalk $D_{\Delta}C_C$is smaller than $C_C$.