• Title/Summary/Keyword: Sustained Production

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Efficacy test of sustained-release somatotropin by implantation in steer, cow and barrow (비육우, 젖소 및 비육돈에서 이식형 소마토트로핀 지속성 제형의 유효성 시험 연구)

  • Kim, Nam Joong
    • Korean Journal of Veterinary Research
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    • v.51 no.1
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    • pp.1-6
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    • 2011
  • Sixteen steers were used to investigate the efficacy of the sustained-release implant of bovine somatotropin (bST) in improving growth and feed:gain ratio during 12 weeks. Administration of the 400 mg bST implant resulted in a 16.1% increase in growth rate, and this increase was significant (p<.05). The use of the sustained-release implant did not alter (p>.05) feed intake and feed:gain ratio. Thirty-four cows were used to investigate the efficacy of the sustained-release implant of bST in milk production during 4 weeks. Administration of the 200 mg bST implant resulted in an 8.7% increase in milk production, and this increase was significant (p<.05). Twenty-four barrows were used to investigate the efficacy of the sustained-release implant of porcine somatotropin (pST) in improving growth, feed:gain ratio and backfat thickness during 6 weeks. Administration of the 120 mg pST implant resulted in a 11.4% increase in feed:gain ratio and a 60% decrease in backfat thickness, and these results were significant (p<.05). But the use of the sustained-release implant did not alter (p>.05) growth rate and feed intake.

Comparative Production of Green Fluorescent Protein Under Co-expression of Bacterial Hemoglobin in Escherichia coli W3110 Using Different Culture Scales

  • Bassapa Johnvesly;Kang, Dong-Gyun;Park, Suk-Soon;Kim, Ji-Hyun;Cha, Hyung-Joon
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.4
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    • pp.274-277
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    • 2004
  • Production of green fluorescent protein (GFP) as a model foreign protein using different culture scales under co-expression of Vitreoscilla hemoglobin (VHb) in the industrial Escherichia coli strain W3110 (a K12 derivative), was examined. It was found that the VHb co-expressing W3110, exhibited an exceptional and sustained production ability during cell cultures using different scales, while the VHb non-expressing strain showed variable production levels. This high and sustained production ability indicates that the VHb co-expressing E. coli W3110, could be successfully employed for practical large-scale production cultures without the need for serious consideration of scale-up problems.

Development of System on the Sustained Production of Chlorine Dioxide Using Polymer Hydrogels (고분자 수화젤을 이용한 이산화염소의 지속적 생성 시스템의 개발)

  • Jeon, Younghyun;Kim, Bumsang
    • Korean Chemical Engineering Research
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    • v.50 no.1
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    • pp.173-176
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    • 2012
  • Chlorine dioxide has an excellent ability to sterilize and deodorize and is harmless to humans. However, it is very unstable and explosive as it is highly concentrated, thus its use in the air clean filed has been limited. Therefore, there is a demand to develop the system to produce a low concentration of chlorine dioxide sustainedly. Here, for a first step in the development of the system on the sustained production of chlorine dioxide, the use of polymer hydrogels was investigated. P(MMA-co-HEMA) hydrogel particles were prepared via dispersion photopolymerization and sodium chlorite and citric acid were loaded respectively in the hydrogel particles. When sodium chlorite and citric acid were reacted with not loaded in the hydrogels, rapid production of chlorine dioxide occurred and the concentration of chlorine dioxide decreased over time. However, when sodium chlorite and citric acid were loaded respectively in the hydrogel particles and reacted, chlorine dioxide was produced slowly and sustainedly because the release of sodium chlorite and citric acid from the hydrogels delayed the reaction between them. The result shows that the use of P(MMA-co HEMA) hydrogels has the potential to develop the system on the sustained production of chlorine dioxide.

Effects of Retinyl Palmitate and Cholecalciferol Added Recombinant BST formulation Treatment on Milk Production and Health in Dairy Cows (Retinyl palmitate와 cholecalciferol이 첨가된 재조합 BST 제제 투여가 젖소의 산유량과 건강에 미치는 영향)

  • Kim, Nam-Joong;Chang, Byoung-Sun;Kim, Doo
    • Journal of Veterinary Clinics
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    • v.19 no.1
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    • pp.43-48
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    • 2002
  • This study was performed to investigate the effects of recombinant BST formulation treatment on the milk yield, milk components, mastitis, and general cow health condition when the formulations of retinyl palmitate, cholecalciferol and rBST were administered after the peak period of milk production. The milk yields of treatment groups (Group I, II, III and IV) were increased from 21.5% to 29.0% than that of control group. There was significant difference in milk production between treatment group II, IV and control group (P<0.05). However, there was no significant difference in milk production between treatment group I, III and control group (P<0.05). And the addition of retinyl palmitate and cholecalciferol into rBST formulation did not increase the milk yield. The milk of treatment groups with sustained-release rBST did not show significant difference in milk components (milk fat, protein, lactose, and solid not fat). However, there were minor changes, primarily in fat content of milk, during the first few weeks of rBST administration. There was no incidence of clinical mastitis between rBST treatment groups and control group. Addition of high and medium concentration of retinyl palmitate and cholecalciferol into sustained-release rBST formulation was efficient in reduction of somatic cell count in milk. There was great energy deficit in all treatment groups compared with control group during the early study period. Thus, the body condition score of all treatment groups showed lower value than control group. No evidences of metabolic health problems, such as ketosis, milk fever, and downer cow were observed. Incidence of general lameness did not appear on all treatment groups during 140 days of this study.

Application of Fuzzy Linear Programming to Estimate the Potentiality of Domestic Long-Term Wood Supply (국내 장기목재공급 잠재력 예측을 위한 퍼지선형계획법의 적용)

  • Won, Hyun-Kyu;Kim, Young-Hwan;Lee, Kyeong-Hak;Jang, Kwang-Min
    • Journal of Korean Society of Forest Science
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    • v.99 no.6
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    • pp.802-807
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    • 2010
  • The objective of this study was to estimate potential of domestic long-term wood supply by using fuzzy linear programming (FLP). In order to construct a numerical formula model, maximization of total timber production was used for the objective function. Size limit of harvesting and sustained yield were used as the constraints. The results of comparison between LP and FLP were shown that LP is more suitable than FLP in terms of the amount of timber production and final forest stock. However, as long-term sustained yield was limitedly achieved by using LP, FLP was more desirable for prediction of potential wood supply. According to the results of this study, the potential of annual domestic wood supply was estimated about 10.5 million cubic meters. Gyeong buk, Jeon nam, Gangwon and Gyeong nam province were highly ranked in order of provincial potential of wood supply.

Sustained Production of Amino Acids by Immobilized Analogue- resistant Mutants of a Cyanobacterium Anacystis nidulans BD-1

  • Bagchi, Suvendra Nath;Rao, Nandula Seshgiri
    • Journal of Microbiology and Biotechnology
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    • v.7 no.5
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    • pp.341-344
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    • 1997
  • Batch cultures of Anacystis nidulans BD-1 resistant to azaleucine and fluorotyrosine produced and liberated a wide range of amino acids, notably glutamic acid, alanine, phenylalanine, leucine, isoleucine, cysteine and methionine. Sustained liberation for prolonged periods was achieved after immobilization on calcium alginate and the net concentration in the medium was 0.18-0.2 g $I^{-1}$. While acetohydroxy acid synthase in azaleucine-resistant mutant lost leucine- and isoleucine-sensitivity, fluorotyrosine-resistant strain turned phenylalanine activating. The activities of nitrate assimilating enzymes were also higher in the mutants and were relaxed from ammonium-repression. The metabolic adjustments involved in amino acid overproduction are discussed.

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R&D Activities, Imperfect Competition and Economic Growth (R&D 및 불완전경쟁과 경제성장)

  • Kim, Byung-Woo
    • Journal of Korea Technology Innovation Society
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    • v.10 no.1
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    • pp.47-72
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    • 2007
  • Ideas do not become exhausted, and there are no diminishing returns in the creation of knowledge. Nonetheless, growth ultimately ceases in this simplest model of endogeneous innovation. The reasons are similar to those that are discussed in the context of the neoclassical model of capital accumulation. Even if the resource cost of creating new goods does not rise, the economic return to invention may decline as the number of available products increases. When the rate of return to R&D falls to the level of the discount rate, private agents cease to be willing to defer consumption in order to invest in product development. But, if we treat knowledge capital as a public capital considering of its non-appropriable benefits, economic growth can be sustained in the economy. Romer(1986) has pointed out that growth might be sustainable if the accumulation of knowledge is not subject to long-run diminishing returns. Actually Romer assumed diminishing returns in the production of private knowledge from available resources, but increasing returns in the production of output from labor and total (public and private) knowledge. His condition for the sustainability of long-run growth amounts to an assumption that the diminishing returns in the former activity do not outweigh the increasing returns in the latter. The Johansen(1988) cointegration test method is used for finding long-run equilibrium relationship between R&D input and the product innovation. Test results indicate the existence of cointegrating equation between each pair of regression variables including dependent variable in the knowledge production function. And, the signs of cointegrating vectors are well accord to the prediction of sustainable growth. In the empirical analysis, from all cases of the form for the knowledge production function, we could not reject the null hypothesis that R&D spillover effect is significant($H_{0}:\;{\gamma}=1$). In summary, we showed that considering goodness of fit of regression model, we can see that the empirical evidence is strongly in favor of the character of knowledge as the public knowledge capital. So, we can expect that by product innovation, economic growth can be sustained in the Korean economy.

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Fire Characteristics of Composites for Interior Panels Using Cone calorimeter (콘칼로리미터를 이용한 내장판용 복합재료의 화재특성)

  • 이철규;정우성;이덕희
    • Journal of the Korean Society for Railway
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    • v.7 no.1
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    • pp.55-59
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    • 2004
  • Composite materials were used widely due to merit of light weight, low maintenance cost and easy installation. But it is the cause of enormous casualties to men and properties because of weak about the fire. Particularly, it is more serious in case of subway train installed composite materials. For this reason, experimental comparison has been done fur measuring heat release rate(H.R.R) and smoke production rate(S.P.R) of interior panels of electric motor car using cone calorimeter. A high radiative heat flux of 50kW/㎡ was used to bum out all materials and to simulate the condition of fully developed fire case in the tests. It was observed that Heat Release Rate and Smoke Production Rate curves were dependent on the kinds of the interior materials. From the heat release rate curves, the sustained ignition time, peak heat release rate and total heat release rate were deduced, These data are useful in classifying the materials by calculating two parameters describing the possibility to flashover.

Biohydrogen production using photosynthesis (광합성을 이용한 바이오수소 생산)

  • Sim, Sang-Jun;Kim, Jun-Pyo
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.06a
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    • pp.478-481
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    • 2006
  • Energy is vital to global prosperity, yet dependence on fossil fuels as our primary energy source contributes to global climate change environmental degradation, and health problems. Hydrogen $(H_2)$ offers tremendous potential as a clean renewable energy currency. Hydrogen has the highest gravimetric energy density of any known fuel and is compatible with electrochemical and combustion processes for energy conversion without producing carbon-based emission that contribute to environmental pollution and climate change. Numerous methodologies have been developed for effective hydrogen production. Among them, the biological hydrogen production has gained attention, because hydrogen can be produced by cellular metabolismunder the presence of water and sunlight. The green alga Chlamydomonas reinhardtii is capable of sustained $H_2$ photoproduction when grown under sulfur deprived condition. Under sulfur deprived conditions, PSII and photosynthetic $O_2$ evolution are inactivated, resulting in shift from aerobic to anaerobic condition in the culture. After anaerobiosis, sulfur deprived algal cells induce a reversible hydrogenase and start to evolve $H_2$ gas in the light. According to above principle, we investigated the effect of induction parameters such as cell age, cell density. light intensity, and sulfate concentration under sulfur deprived condition We also developed continuous hydrogen production system by sulfate re-addition under sulfur deprived condition.

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Changes in Photosynthetic Characteristics during Grain Filling of a Functional Stay-Green Rice SNUSG1 and its $F_1$ Hybrids

  • Fu, Jin-Dong;Lee, Byun-Woo
    • Journal of Crop Science and Biotechnology
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    • v.11 no.1
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    • pp.75-82
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    • 2008
  • Functional stay-green is a beneficial trait that may increase grain yield through the sustained photosynthetic competence during monocarpic senescence in cereal crops. The temporal changes of photosynthesis and related characteristics throughout the grain filling period of a stay-green japonica rice "SNU-SG1" was compared in growth chamber conditions with three high-yielding cultivars(HYVs) and their $F_1$ hybrids with SNU-SG1. SNU-SG1 exhibited a typical characteristic of functional stay-green in terms of chlorophyll degradation and photosynthetic competence during grain filling. According to the photosynthesis-light response curve measured at 10 and 35 d after heading for the flag leaf, SNU-SG1 exhibited higher initial light conversion efficiency and thus higher gross photosynthetic rate at light saturation compared to HYVs. Light saturation point was not different among genotypes, ranging from 1000 to 1500 ${\mu}mol$ photon $m^{-2}s^{-1}$. Net photosynthetic rate at light saturation($P_{max}$) of the upper four leaves in SNU-SG1 was much higher and sustained longer throughout grain-filling than HYVs and $F_1$ hybrids. The sustained high photosynthetic competence of SNU-SG1 during grain filling was ascribed to the longer maintenance of high mesophyll conductance that resulted from not only high chlorophyll content and its delayed degradation but also the slow degeneration of photosystem II(PS II) as judged by chlorophyll fluorescence($F_v/F_m$) of flag leaves. $F_1$ hybrids showed slow degeneration of photosystem II similar to the male parent SNU-SG1 while chlorophyll degradation pattern close to female parents, thus exhibiting a little higher $P_{max}$ than female parents. These results suggest that SNU-SG1 has a typical functional stay-green trait that can be utilized for increasing rice yield potential through the improved dry matter production during grain filling.

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