Browse > Article

Effects of Retinyl Palmitate and Cholecalciferol Added Recombinant BST formulation Treatment on Milk Production and Health in Dairy Cows  

Kim, Nam-Joong (LG Chem Investment Ltd., Life Science R&D, Animal Health Research)
Chang, Byoung-Sun (LG Chem Investment Ltd., Life Science R&D, Animal Health Research)
Kim, Doo (College of Veterinary Medicine, Kagnwon National University)
Publication Information
Journal of Veterinary Clinics / v.19, no.1, 2002 , pp. 43-48 More about this Journal
Abstract
This study was performed to investigate the effects of recombinant BST formulation treatment on the milk yield, milk components, mastitis, and general cow health condition when the formulations of retinyl palmitate, cholecalciferol and rBST were administered after the peak period of milk production. The milk yields of treatment groups (Group I, II, III and IV) were increased from 21.5% to 29.0% than that of control group. There was significant difference in milk production between treatment group II, IV and control group (P<0.05). However, there was no significant difference in milk production between treatment group I, III and control group (P<0.05). And the addition of retinyl palmitate and cholecalciferol into rBST formulation did not increase the milk yield. The milk of treatment groups with sustained-release rBST did not show significant difference in milk components (milk fat, protein, lactose, and solid not fat). However, there were minor changes, primarily in fat content of milk, during the first few weeks of rBST administration. There was no incidence of clinical mastitis between rBST treatment groups and control group. Addition of high and medium concentration of retinyl palmitate and cholecalciferol into sustained-release rBST formulation was efficient in reduction of somatic cell count in milk. There was great energy deficit in all treatment groups compared with control group during the early study period. Thus, the body condition score of all treatment groups showed lower value than control group. No evidences of metabolic health problems, such as ketosis, milk fever, and downer cow were observed. Incidence of general lameness did not appear on all treatment groups during 140 days of this study.
Keywords
somatotropin; retinyl palmitate; cholecalciferol; milk production; somatic cell count;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Characterization and formulation consideration for recombinantly derived bovine somatotropin /
[ Stephen RD;Michael JH ] / Pharm Biotechnol
2 Bovine ketosis and somatotrophin: risk factors for ketosis and effects of ketosis on health and production /
[ Lean IJ;Bruss ML;Troutt HF;Galland JC;Farver TB;Rostami J;Holmberg CA;Weaver LD ] / Res Vet Sci   DOI   ScienceOn
3 Bovine somatotropin: review of an emerging animal technology /
[ Bauman DE ] / J Dairy Sci   DOI   ScienceOn
4 Effects of bovine somatotropin on physiologic responses of lactating Holstein and Jersey cows during hot, humid weather /
[ West JW;Mullinix BG;Sandifer TG ] / J Dairy Sci   DOI   ScienceOn
5 Lactational response of Jersey cows to bovine somatotropin administered daily or in a sustained-release formulation /
[ Jenny BF;Grimes LW;Pardue FE;Rock DW ] / J Dairy Sci   DOI   ScienceOn
6 Effects of recombinant methionyl bovine somatotropin(Sometribove) in high producing cows milked three times daily /
[ Jordan DC;Aguilar AA;Olson JD;Bailey C;Hartnell GF;Madsen KS ] / J Dairy Sci   DOI   ScienceOn
7 Somatotropin compositions mixed with vitamins /
[ Kim NJ;Ryoo JP;Chang BY;Kim D ] / International Publication Number WO 99/43342
8 Preformulation studies oriented toward sustained delivery of recombinant somatotropin /
[ Michael JH;Juliane MB;Peggy LP;Richard TD ] / J Agric Food Chem   DOI
9 Milking management /
[ Leaver JD ] / Milk production, science and practice
10 Use of bovine somatotropin in the tropics: the effect of sometribove on milk production in western, eastern, and southern Africa /
[ Phipps RH;Hard DL;Adriaens F ] / J Dairy Sci   DOI   ScienceOn
11 Response of dairy cows to high doses of sustained-release bovine somatotropin administered during two lactations. 2. Health and reproduction /
[ Cole WJ;Eppard PJ;Boysen BG;Madsen KS;Sorbet RH;Miller MA;Hintz RL;White TC;Ribelin WE;Hammond BG;Collier RJ;Lanza GM ] / J Dairy Sci   DOI   ScienceOn
12 Effects of recombinant bovine somatotropin and dietary energy intake on growth, secretion of leteinizing hormone, follicular development and onset of puberty in beef heifers /
[ Hall JB;Schillo KK;Fitzgerald BP;Bradley NW ] / J Anim Sci   DOI
13 Comparison of somatotropin and growth hormone-releasing factor on milk yield, serum hormones, and energy status /
[ Dahl GE;Chapin LT;Allen MS;Moseley WM;Tucker HA ] / J Dairy Sci   DOI   ScienceOn
14 A preliminary report on a prolonged release formulation of bovine somatotropin with particular reference to animal health /
[ Phipps RH;Weller RF;Austin AR;Craven N;Peel CJ ] / Vet Rec   DOI   ScienceOn
15 Mastitis of dairy cows /
[ John KW ] / Farm animal health and disease control(2nd ed.)
16 /
[ Nicholas HB;Leslie EM ] / Veterinary pharmacology and therapeutics(6th ed.)
17 Growth, reproductive performance, mammary development, and milk production of beef heifers as influenced by prepubertal dietary energy and administration of bovine somatotropin /
[ Buskirk DD;Faulker DB;Hurley WL;Kesler DJ;Ireland FA;Nash TG;Castree JC;Vicini JL ] / J Anim Sci   DOI
18 Effect of a prolonged-release formulation of N-methionyl bovine somatotropin (sometribove) on milk fat /
[ Lynch JM;Barband DM;Bauman DE;Hartnell GF;Nemeth MA ] / J Dairy Sci   DOI   ScienceOn
19 Postparturient metabolic and production responeses in cows previously exposed to long-term treatment with somatotropin /
[ Lean IJ:Troutt HF;Bruss ML;Farver TB;Baldwin RL;Galland JC;Kratzer D;Holmberg CA;Weaver LD ] / J Dairy Sci   DOI   ScienceOn
20 Effects of diet and bovine somatotropin on heifer growth and mammary development /
[ Radcliff RP;VandHarr MJ;Skidmore AL;Chapin LT;Radke BR;Lloyd JW;Stanisiewski EP;Tucker HA ] / J Dairy Sci   DOI   ScienceOn
21 Effect of prolonged-release formulation of N-methionyl bovine somatotropin (sometribove) on milk composition /
[ Barbano DM;Lynch JM;Bauman DE;Hartnell GF;Hintz RL;Nemeth MA ] / J Dairy Sci   DOI   ScienceOn
22 Observations on intramammary infection and somatic cell counts in cows treated with recombinant bovine somatotropin /
[ Lissemore KD;Leslie KE;McBride BW;Burton JH;Willan AR;Bateman KG ] / Can J Vet Res