• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3653-3656
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• 2012

Background: A number of effective prevention measures have been introduced in attempts to substantially reduce both the incidence and mortality due to many kinds of cancer. The search for new anti-cancer compounds in foods or in plant medicines is one realistic and promising approach to prevention. Chinese medicines provide a rich pool of novel and efficacious agents for cancer prevention and treatment. Previously it was demonstratrated that hyperin extracted from the Manchurian rhododendron leaf reduces the proliferation of many cancer cells. The present study was carried out to evaluate its effects on human endometrial cancer cell viability and apoptosis and to investigate its mechanisms of action in RL952 cells. Methods: Cell viability was measured using the MTT assay. Intracellular calcium ions were detected using laser-scanning confocal microscopy. The effects of hyperin on apoptosis related proteins in RL952 cells were examined using Western blot analysis. Results: The growth of RL952 cells was inhibited by treatment with hyperin. OD values of caspase-3 and caspase-9 were increased and expression of bcl-2 was increased and bax was decreased in protein levels in RL952 cells after 24 h of hyperin treatment, Moreover, intracellular calcium accumulation occurred in hyperin-treated cells. Conclusion: These results suggest that hyperin may play an important role in tumor growth suppression by inducing apoptosis in human endometrial cells via a $Ca^{2+}$-related mitochondrion apoptotic pathway in RL952 cells.

• Fire Science and Engineering
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• v.34 no.4
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• pp.125-134
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• 2020

This paper aimed to statistically analyze the impact of fire needs not considered in previous reports based on preventive and preparedness strategies of fire administration and fire budget.. The panel data came from 16 metropolitan councils from 2008 to 2018 and was statistically analyzed based on the preventive measures of the fire administration (agreement for building permission, specific target for fire-fighting, public use facilities, and special fire inspection [SFI]), preparedness of the fire administration (fire safety education [FSE]), response of the fire administration (mobilization for fire suppression [MFS] and mobilization for ambulance service [MAS]), and fire budget. In the results, SFI, FSE, and MFS had a significant negative influence on the fire budget. Meanwhile, MAS had a significant positive effect on the fire budget (p < 0.01). These results reflect public policy in Korea; there has been a paradigm shift in fire administration: from disaster acceptance (focusing on recovery) to disaster response (focusing on field response) to disaster preparedness (focusing on preparedness).

• Journal of the Society of Disaster Information
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• v.13 no.4
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• pp.529-536
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• 2017

In this study, the perceptions were surveyed fire risk and flash flames concerning the firefighters. The results were statistically evaluated according to age, experience and rank. More than 70% of the respondents answered that there is a possibility of unexpected flame exposure in the field of fire, but there was no recognition difference according to age, experience and rank. However, if there is an emergency situation in the field of fire, the survey on the ability to cope with crises showed that there is a difference in perception depending on the age, career, and rank of respondents. From these results, it is expected that strengthening simulation training of unexpected situation will be more urgently required in the future, and measures should be taken to minimize human accidents through improvement of standard operation procedures or supplement of fire suppression education according to unexpected situation.

• Research in Plant Disease
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• v.14 no.1
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• pp.32-36
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• 2008

Bacterial wilt caused by Ralstonia solanacearum has become a severe problem on tomato in Korea and no effective control measures are available yet. Pseudomonas species play key roles for the biocontrol of many plant diseases especially in soil. A rhizobacterial population of 150 Pseudomonas strains, isolated from the rhizosphere soil of various plants grown at different sites, was screened for 2,4-diacetylphloroglucinol producing gene (PhlD) by PCR. Two strains (P83 and P84) among them were found to be phlD positive. When the isolates were analysed by 16S rDNA (Sensu Stricto), all isolates yielded amplified products of 1,018bp. Of the 150 isolates of Pseudomonas spp., a bacterial strain P. putida P84 isolated from tomato rhizosphere showed to suppress a wide range of phytopathogenic bacteria in vitro. The best source of carbon for P84 strain were glucose, arabinose, inositol and melibiose. In greenhouse experiments, P84 strain suppressed the development of bacterial wilt in tomato with a control value of 60%.

• The Plant Pathology Journal
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• v.39 no.1
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• pp.52-61
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• 2023

Fire blight, caused by Erwinia amylovora, is one of the major bacterial disease of apple and pear, causing enormous economic losses worldwide. Several control measures against E. amylovora have been reported till date, however, none of them have proved to be effective significantly against the pathogen. In this study, mechanisms of the copper-based control agents (CBCAs): copper oxychloride (COCHL), copper oxide (COX), copper hydroxide (CHY), copper sulfate basic (CSB), and tribasic copper sulfate (TCS) and their disease severity reduction efficacy against E. amylovora were analyzed. Bis-1,3-dibutylbarbituric acid trimethine oxonol, carboxyl fluorescein diacetate succinimidyl ester, and 5-cyano-2,3-ditolyl tetrazolium chloride staining were used to check the damage of membrane potential, cytoplasmic pH_in, and respiration of CBCAs-treated E. amylovora, respectively. High disturbance in the membrane potential of E. amylovora was found under COX and COCHL treatments. Similarly, higher significant changes in the inner cytoplasmic pH_in were observed under COX, COCHL, and TCS treatment. CHY and COCHL-treated E. amylovora showed a significant reduction in respiration. In vitro bioassay results revealed that CHY, CSB, and TCS at 2,000 ppm reduced the severity of fire blight both in pre- and post-treatment of CBCAs in immature apple fruits and seedlings. Overall, the most effective CBCAs against E. amylovora could be CHY at 2,000 ppm as its showed inhibition mechanisms and disease severity reduction.

• Nuclear Engineering and Technology
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• v.55 no.12
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• pp.4570-4575
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• 2023

Noise and Radio-frequency interference or RFI causes a significant restriction on the Free induction Decay or FID signal detection of the Nuclear Quadrupole Resonance procedure. Therefore, using this method in non-isolated environments such as industry and ports requires extraordinary measures. For this purpose, noise reduction algorithms and increasing signal-to-noise-and-interference ratio or SNIR have been used. In this research, sodium nitrite has been used as a sample and algorithms have been tested in a non-isolated environment. The resonant frequencies for the 150 g of test sample were measured at 303 K at about 1 MHz and 3.4 MHz. The main novelty in this study was, (1) using two types of antennas in the receiver to improve adaptive noise and interference cancellation, (2) using a separate helical antenna in the transmitter to eliminate the duplexer, (3) estimating the noise before sending the pulse to calculate the weighting factors and reduce the noise by adaptive noise cancellation, (3) reject the interference by blanking algorithm, (4) pulse integration in the frequency domain to increase the SNR, and (5) increasing the detection speed by new pulse integration technique. By interference rejection and noise cancellation, the SNIR is improved to 9.24 dB at 1 MHz and to 7.28 dB at 3.4 MHz, and by pulse integration 44.8 dB FID signal amplification is achieved, and the FID signals are detected at 1.057 MHz and 3.402 MHz at room temperature.

• (The)Study of the Eastern Classic
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• no.70
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• pp.407-434
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• 2018

This study took a look at the crossing the border into Liadong in the early Joseon Dynasty, which has nearly not been paid attention to in the history of the Buddhism in Korea, and the Chinese, Buddhist whereabouts of Monk Mangong and Jeokhyu, the periodical, Buddhist priests. Regarding the large-scale, Buddhist oppression measures of King Taejong in the beginning of the Joseon Dynasty and King Sejong, the Buddhist circle did not not respond helplessly, but, rather, it had made the resistance on its own way. Especially, the Naonghyegeum of Jogyeseonjong and the disciple affiliates of Taegobowu had stood out. The disciples of Bowu had mainly hit the Sinmungo or had advocated the self-purification of Buddhism. And the disciple affiliates of Naong either had reorganized the Buddhist circle with Muhak in the center or had opposed the suppression. And, by receiving the help of the Emperor of the Ming Dynasty, they had intended to protect the Buddhist circle, or they, also, crossed the border into Liadong. Although, while attempting the crossing the border into another territory, they were arrested like the sea ships, like Mangong of King Taejong and Jeokhyu of King Sejong, they succeeded in crossing the border into another territory, and they left the clear whereabouts in the Chinese, Buddhist circle. Mangong was one Buddhist monk among the 11 Buddhist monks who crossed the border into Liadong during the King Taejong. After crossing the border, Mangong had moved again from Beijing on a sea route and had settled for after going into a mountain in the Zen sect at the Tienchieh temple in Nanjing. Meanwhile, he had been close to the Joseon Dynasty, and he relocated to Mount Taishan, where there had been the history, thereby rebuilding the Chikurin Temple and the Buchauchan temple and widely publicizing the Buddhism. During the time of King Sejong, by crossing the border into Liadong together with a total of 10 Monks, including the Buddhist monks Shinnae, Shinhyu, Shindam, Hyeseon, Hongjeok, Haebi, Shinyeon, Honghye, Shinwun, etc., under the protection by the Emperor of the Ming Dynasty in Beijing, Jeokhyu went through Shanhaiguan and had moved to the Tienchieh Temple in Nanjing. Although their whereabouts can not be known, on the Guji Mountain in Beijing, Jeokhyu founded the Banyaseonsa Temple nearby the Ryeongamseonsa Temple, where the clergy and the laity of the Goryeo Dynasty had resided and, especially, where Naong and the disciples of Muhak etc. had stayed. As such, the Buddhist monks in the beginning of the Joseon Dynasty had either resisted the suppression by the country or crossed the border into another territory. Mangong and Jeokhyu of the times of King Taejong and King Sejong had led the Chinese, Buddhism circle, had rebuilt the Buddhist temples, and had contributed to the development of the Chinese Buddhism.

• Convergence Security Journal
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• v.14 no.6_1
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• pp.129-138
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• 2014

South Korea should correspond to the primary threat to North Korea's nuclear weapons. It is necessary to have countermeasures to solve the realistic problems of North Korea's nuclear weapons. We can intensify military pact between the United States and Korea and at the same time strengthening the current military power. Currently, we take note the threat North Korea's missile. We can not control the development of a nuclear weapon and there are possibilities that North Korea have successfully miniaturized nuclear enough to carry by the missile. We should overview and check the Korea's missile defenses system. While the direction of the overall missile defense system deployment with a focus on lower and upper air defense network. And discuss defense research should be to build a system that can be protected with a key strategic facilities and cities. While North Korea have nuclear weapon, the main issues related to North Korea's nuclear threat. The six party talks countries try to solve the problem by the international and diplomatic approach. At the same time we should make somewhat to defend measures such as military defenses of Kill chain system to protect our country. Kill Chain is on of the effective defense system. We know that North Korea do not abandon to develop nuclear weapons by diplomatic efforts. We should performed in fact by a variety of military suppression method.

• Journal of Hospice and Palliative Care
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• v.20 no.3
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• pp.159-166
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• 2017

According to the advance of antiretroviral regimen and the early treatment strategy, people living with human immunodeficiency virus (PLWH) are achieving the goal of virologic suppression and immune restoration. Most of them no more die of acquired immunodeficiency syndrome (AIDS) defining illnesses, and become older with chronic comorbidities such as cardiovascular, metabolic, hepatic, renal and neurological diseases. However some PLWH still visit hospitals as late presenters with very low CD4+ T cell counts, so that they suffer AIDS defining illnesses to die or experience severe neurological complications resulting in disabilities. Early palliative interventions are needed on the various symptoms of PLWH. Thus far chronic pains such as distal symmetric sensory polyneuropathies have been underevaluated. Active pain-relieving interventions are important to them. Recently we define end of life condition of human immunodeficiency virus (HIV) or eligibility to hospice care after adjusting current status of HIV treatment. Hospice teams should pay attention to the specific medical conditions, psychological needs, and social circumstances of PLWH. With just standard precautions as common infection control measures, general hospice cares can be provided to them like to other hospices subjects. For giving PLWH opportunities to have the end of life with value and dignity, hospice multidisciplinary team should intervene them early and aggressively. Now we need more clinical experiences and institutional improvements.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.9A
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• pp.737-748
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• 2005

Two flexible admission control schemes for integrated voice and stream-type data services are proposed in DS-CDMA systems. Most Previous studies on admission control have focused on integration of short, bursty Packet-type data services and conventional voice services. However, stream-type data services with a relatively long service holding time are expected to be a considerable portion of data traffic in future generation cellular systems. Scheme I is a basic scheme that accommodates both voice and data services with full bandwidth. However, voice services are given priority over data services using the duration difference between the holding times for these services. Scheme ll uses a different method to efficiently give priority to voice services over stream-type data services. An additional interference margin for voice services is provided by suppressing interference from stream-type data services according to voice access requests and a varying interference status. Performance of the two schemes is evaluated by developing Markovian models. Numerical results show that the voice capacity is highly sensitive to the service holding time of data services while the performance measures of data services are not highly sensitive. Scheme H is a significant improvement over Scheme I for accommodating voice and stream-type data services