• The Korean Journal of Emergency Medical Services
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• v.10 no.1
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• pp.61-70
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• 2006

Purpose: The purpose of this study was to prevent the Aged from encountering a sudden accident in an emergency situation caused by drinking, help them have better awareness of drinking problems, and provide basic data for forming sound drinking. Method: A descriptive approach was made to the occurrence of emergency situations caused by drinking for the aged by reviewing literature concerning the subject, along with the analysis of the actual condition through the cases of emergency situations. Result: The Aged had a drink to drown their loneliness due to the loss of social belonging and solitude and attempt suicide, relied on drinking due to the loss of economic roles and reduced income to cause emergency situations, drove when drunken to bring emergency situations to themselves and others, and committed incendiarism after drinking due to social dissatisfaction and mental problems. Conclusion: It is necessary to develop leisure management programs positively and provide an opportunity for sound living culture to old people so that they can have sound entertainment culture other than drinking; such educational programs will serve to form healthy society with no emergency situation caused by the Aged drinking.

• Journal of Korean Academy of Nursing Administration
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• v.8 no.2
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• pp.273-281
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• 2002

Purpose. The study was done to develop nursing guidelines to prevent nursing negligence in the clinical setting that would lead to malpractice. Method. A comprehensive review of the literature and focus groups interviews were used to search for malpractice cases related to "observation", one of the most basic nursing activities. The cases were analyzed with respect to nursing practice and a legal expert was consulted on the content. Results. 4 malpractice cases related to observation negligence were selected for this study; 1) a case of failing to observe dyspnea after a thyroidectomy, 2) a case of failing to observe a depressed patient for suicide attempts, 3) a case of failing to observe a VP shunt obstruction, 4) a case of failing to observe a cardiac ischemia after a bronchoscopy. 11 guidelines were developed for clinical nurses and 13 guidelines for nursing managers. Conclusion. These guidelines are useful in preventing malpractice due to nursing negligence. Therefore nurses need to apply them to their practices and continue to make an effort to develop guidelines for other malpractice situations.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.15 no.1
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• pp.107-113
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• 2008

Purpose: The purpose of this study was to identify the degree and relationship between self-esteem, depression, and suicidal ideation of youths in the auxiliary police force. Method: This descriptive study was conducted using a structured questionnaire from February 1 to March 25, 2007. The participants were 180 youths from 19 to 25 years old (average 20.82 years old) who were auxiliary policemen. The data were analyzed using the SPSS Win 12.0 program. Results: Six of the auxiliary police (3.34%) reported critical scores in suicidal ideation. There was a significant difference in depression according to work area. Self-esteem showed a significant negative correlation with depression (r=-0.38, p<.001) and suicidal ideation (r=-0.39, p<.001). There was a positive correlation between depression and suicidal ideation(r=0.53, p<.001). Conclusion: The findings suggest that auxiliary policemen have higher levels of depression and suicidal ideation. Therefore, further study is needed to develop and examine nursing interventions the enhance self-esteem, so that depression and suicidal ideation can be minimized.

• Journal of Korean Public Health Nursing
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• v.27 no.1
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• pp.5-15
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• 2013

Purpose: The purpose of this study was to determine factors related to regular walking exercise in the elderly using KNHNES data. Method: The study subjects, a total of 1437 adults over age 65, were classified into two groups based on their type of walking exercise: regular walking exercise group or irregular walking exercise group. The study variables were measured using scale physiological function, mental health status, chronic disease and quality of life. Results: The data was analyzed by $x^2$-test, t-test, and logistic regression using the SPSS 18.0 program. The factors related to regular walking exercise were male (OR=0.628, 95%CI=0.503-0.783), subjective health state (OR=0.832, 95%CI=0.751-0.921), thoughts of suicide (OR=0.753, 95%CI=0.586-0.967), hypoHDL-cholesterolemia (OR=0.742, 95%CI=0.591-0.930), and stroke (OR=0.604, 95%CI=0.366-0.997). Conclusion: The findings indicate that regular walking exercise in the elderly is related to physiological function, mental health status, and chronic disease. Therefore, providing for the education and awareness of health promotion for the elderly will may improve the quality of life in old age.

• The Journal of Korean Academic Society of Nursing Education
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• v.16 no.1
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• pp.43-50
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• 2010

Purpose: This study was conducted to identify the effect of family function and self-efficacy on suicidal ideation in university students. Method: The study was designed as a descriptive survey study. Data was collected using a structured questionnaire which included general characteristics, measures of family function, self-efficacy and suicidal ideation. Data collection was done between April 1 and April 30, 2009 with 569 university students. Data was analyzed using descriptive statistics, ANOVA, and Pearson's correlation coefficients. Result: The score of family function showed a significantly negative correlation with suicidal ideation. The score of self-efficacy also showed a significantly negative correlation with suicidal ideation. Family function in university students was significantly influenced by gender. Family cohesion was significantly influenced by religion. Self-efficacy in university students was significantly influenced by gender and age. Suicidal ideation was significantly influenced by religion. Conclusion: The findings suggest that family function and self-efficacy influence suicidal ideation. A strategy for improving family function and self-efficacy should be identified to decrease suicidal ideation.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2789-2800
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• 2013

Background: The aim of this systematic review was to investigate whether stem cells could be effectively applied in targeted therapy of breast cancer. Material and Method: A systematic literature search was performed for original articles published from January 2007 until May 2012. Results: Nine studies met the inclusion criteria for phase I or II clinical trials, of which three used stem cells as vehicles, two trials used autologous hematopoetic stem cells and in four trials cancer stem cells were targeted. Mesenchymal stem cells (MSCs) were applied as cellular vehicles to transfer therapeutic agents. Cell therapy with MSC can successfully target resistant cancers. Cancer stem cells were selectively targeted via a proteasome-dependent suicide gene leading to tumor regression. $Wnt/{\beta}$-catenin signaling pathway has been also evidenced to be an attractive CSC-target. Conclusions: This systematic review focused on two different concepts of stem cells and breast cancer marking a turning point in the trials that applied stem cells as cellular vehicles for targeted delivery therapy as well as CSC-targeted therapies. Applying stem cells as targeted therapy could be an effective therapeutic approach for treatment of breast cancer in the clinic and in therapeutic marketing; however this needs to be confirmed with further clinical investigations.

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.4
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• pp.79-90
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• 2015

Purpose : The purpose of this study was to investigate related factors contributing to subjective health state in elderly people with focus on comparison of gender differences. Method : From the database of the Korean National Health and Nutrition Examination Survey(KNHNES) the year 2012 and 2013, the researchers selected 2,924 old adults aged over 65. Data were analyzed with SPSS 18.0 program. Result : Results indicated that education, occupation, restriction of activity, stress, drinking status were significant variables of subjective health state both men and women. But, age, DM, MI, arthritis, smoking status were significant variables of subjective health state of men. And insurance, suicide, HTN, walking exercise were significant variables of subjective health state of women. Conclusion : The development of health and quality of life for elderly people considers different approaches to the genders.

• The Journal of Korean Academic Society of Nursing Education
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• v.20 no.4
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• pp.650-658
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• 2014

Purpose: This study compares differences in stress, depression and suicidal ideation between nursing and students of other academic disciplines. Method: Nursing students (n=105) and students of other majors (n=148) were surveyed on the degree of personal stress, depression and suicidal ideation. Participants were recruited from three universities in cities S and C in Korea. Data were collected from May 1 to 20, 2013. Measurement tools were the Revised Life Stress Scale for College Students, Center for Epidemiological Studies-Depression Scale(CES-D), and Scale for Suicide Ideation(SSI). PASW Statistics 18 was used for descriptive analysis, homogeneity test(chi-square distribution) and ANCOVA. Results: The level of stress among nursing students was lower than that of students in other majors. Among the subcategories of stress, however, stress among nursing students arising from the student-faculty relationship was higher than that of their non-nursing counterparts. Conversely, differences in the prevalence of depression were notsignificant between nursing students and non-nursing students. Ultimately, it was revealed that there exists a strong correlation among stress, depression and suicidal idea for nursing students. Conclusion: Developing stress and depression management programs for nursing students is highly recommended.

• Journal of Korean Academy of Nursing
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• v.34 no.1
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• pp.102-110
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• 2004

Purpose: This study was done to identify the state of internet addiction and to investigate the relationships among internet addiction, depression and suicidal ideation in adolescents. Method: Participants were 1,670 high school students in an urban city. The Internet Addiction Scale was used to measure internet addiction, the DISC-MDD-SQ was used to measure depression, and the Suicidal Ideation Questionnaire-JR was used to measure suicidal ideation. Result: 38.1 % of participants were perceived to be in the early stages of internet addiction and 1.5% reported heavy addiction. Overall the internet addiction scale score was 37.57(${\pm12.52}$). The differences of internet addiction in sample characteristics were found to be significant in rank in class. The differences in DISC-MDD-SQ and IAS scores among the states of internet addiction were statistically significant. The level of internet addiction correlated positively to the level of depression and suicidal ideation. Conclusion: Based upon these findings, there were significant positive correlations among Internet addiction, depression, and suicidal ideation in adolescents. As schools are often the first line for the identification of potential life-threatening behaviors, nurses, especially school-based health professionals, need to be cognizant of measures and procedures for the assessment of Internet addiction, depression, and suicidal ideation.

• Journal of Microbiology and Biotechnology
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• v.4 no.3
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• pp.165-170
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• 1994

An efficient and convenient method of introducing transposable elements into acetic acid bacteria was developed by the method of conjugal transfer. The ampicillin-resistant strain, Acetobacter sp. HA, was selected to be conjugated with two E. coli strains, WA803 containing pGS9 and AC8001 harboring pJB4JI. The Tn5 containing suicide vector pGS9 or pJB4JI, was transferred from E. coli to Acetobacter sp. HA and kanamycin-ampicillin-resistant transconjugants obtained at high frequencies. The conjugal frequencies of pGS9 and pJB4JI were 6.20$\times$$l0^{-1} and 2.79$\times$l0{-1}$ per recipient, respectively. The transfer method was applied on four different strains of Acetobacter. The conjugal transfer frequencies ranged from 2.00$\times$$l0^{-2} to 4.45$\times$l0^{-8}$ per recipient in the three strains. Some transconjugants tested were found to contain Tn5 DNA in their genomes and this was confirmed by Southem blot analysis. This is the first study which shows that Tn5 mutagenesis can be applied to successfully isolate mutants of Acetobacter genus.