Application of Stem Cells in Targeted Therapy of Breast Cancer: A Systematic Review |
Madjd, Zahra
(Department of Pathology, Iran University of Medical Sciences)
Gheytanchi, Elmira (Oncopathology Research Centre, Iran University of Medical Sciences) Erfani, Elham (Oncopathology Research Centre, Iran University of Medical Sciences) Asadi-Lari, Mohsen (Department of Epidemiology, Oncopathology Research Centre, Iran University of Medical Sciences) |
1 | Ablett MP, Singh JK, Clarke RB (2012). Stem cells in breast tumours: are they ready for the clinic? Eur J Cancer, 48, 2104-16. DOI ScienceOn |
2 | Aboody KS, Najbauer J, Danks MK (2008). Stem and progenitor cell-mediated tumor selective gene therapy. Gene Ther, 15, 739-52. DOI ScienceOn |
3 | Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF (2004). Therapeutic implications of cancer stem cells. Curr Opin Genet Dev, 14, 43-7. DOI ScienceOn |
4 | Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003). Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA, 100, 3983-8. DOI ScienceOn |
5 | Austin J, Kimble J (1987). glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell, 51, 589-99. DOI ScienceOn |
6 | Ayyanan A, Civenni G, Ciarloni L, et al (2006). Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc Natl Acad Sci USA, 103, 3799-804. DOI ScienceOn |
7 | Bafico A, Liu G, Goldin L, Harris V, Aaronson SA (2004). An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell, 6, 497-506. DOI ScienceOn |
8 | Balicki D (2007) Moving forward in human mammary stem cell biology and breast cancer prognostication using ALDH1. Cell Stem Cell, 1, 485-7. DOI ScienceOn |
9 | Banna GL, Simonelli M, Santoro A (2007) High-dose chemotherapy followed by autologous hematopoietic stemcell transplantation for the treatment of solid tumors in adults: a critical review. Curr Stem Cell Res Ther, 2, 65-82. DOI |
10 | Barker N, Clevers H (2006). Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov, 5, 997-1014. DOI ScienceOn |
11 | Behbod F, Rosen JM (2005) Will cancer stem cells provide new therapeutic targets? Carcinogenesis, 26, 703-11. DOI ScienceOn |
12 | Berry DA, Ueno NT, Johnson MM, et al (2011) High-dose chemotherapy with autologous stem-cell support as adjuvant therapy in breast cancer: overview of 15 randomized trials. J Clin Oncol, 29, 3214-23. DOI ScienceOn |
13 | Bohl SR, Pircher A, Hilbe W (2011) Cancer stem cells: characteristics and their potential role for new therapeutic strategies. Onkologie, 34, 269-74. DOI ScienceOn |
14 | Chaffer CL, Brueckmann I, Scheel C, et al (2011). Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci USA, 108, 7950-5. DOI ScienceOn |
15 | Chan EF, Gat U, McNiff JM, Fuchs E (1999). A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet, 21, 410-3. DOI ScienceOn |
16 | Clarke MF, Dick JE, Dirks PB, et al (2006). Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res, 66, 9339-44. DOI ScienceOn |
17 | Coffelt SB, Marini FC, Watson K, et al (2009). The proinflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. Proc Natl Acad Sci USA, 106, 3806-11. DOI ScienceOn |
18 | Cosse JP, Michiels C (2008). Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression. Anticancer Agents Med Chem, 8, 790-7. DOI ScienceOn |
19 | Del Bufalo D, Biroccio A, Soddu S, et al (1996). Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene. J Clin Invest, 98, 1165-73. DOI |
20 | Curtin JC, Lorenzi MV (2010). Drug discovery approaches to target Wnt signaling in cancer stem Cells. Oncotarget, 1, 552-66. |
21 | Deonarain MP, Kousparou CA, Epenetos AA (2009) .Antibodies targeting cancer stem cells: a new paradigm in immunotherapy? MAbs, 1, 12-25. DOI |
22 | Dickinson ME, McMahon AP (1992). The role of Wnt genes in vertebrate development. Curr Opin Genet Dev, 2, 562-6. DOI ScienceOn |
23 | Duan X, Guan H, Cao Y, Kleinerman ES (2009). Murine bone marrow-derived mesenchymal stem cells as vehicles for interleukin-12 gene delivery into Ewing sarcoma tumors. Cancer, 115, 13-22. DOI ScienceOn |
24 | Dwyer RM, Potter-Beirne SM, Harrington KA, et al (2007). Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells. Clin Cancer Res 13(17): 5020-7. DOI ScienceOn |
25 | Dwyer RM, Ryan J, Havelin RJ, et al (2011). Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer. Stem Cells 29(7): 1149-57. DOI ScienceOn |
26 | El-Haibi CP, Karnoub AE (2010). Mesenchymal stem cells in the pathogenesis and therapy of breast cancer. J Mammary Gland Biol Neoplasia, 15, 399-409. DOI ScienceOn |
27 | Ellisen LW, Bird J, West DC, et al (1991). TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell, 66, 649-61. DOI ScienceOn |
28 | Evangelista M, Tian H, de Sauvage FJ (2006). The hedgehog signaling pathway in cancer. Clin Cancer Res, 12, 5924-8. DOI ScienceOn |
29 | Gailani MR, Bale AE (1999). Acquired and inherited basal cell carcinomas and the patched gene. Adv Dermatol, 14, 261-83; discussion 284. |
30 | Franovic A, Gunaratnam L, Smith K, et al (2007). Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer. Proc Natl Acad Sci USA, 104, 13092-7. DOI ScienceOn |
31 | Giles RH, van Es JH, Clevers H (2003). Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta, 1653, 1-24. |
32 | Ginestier C, Hur MH, Charafe-Jauffret E, et al (2007). ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell, 1, 555-67. DOI ScienceOn |
33 | Ginestier C, Wicha MS (2007). Mammary stem cell number as a determinate of breast cancer risk. Breast Cancer Res, 9, 109. DOI |
34 | Grisendi G, Bussolari R, Cafarelli L, et al (2010). Adiposederived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy. Cancer Res, 70, 3718-29. DOI |
35 | Gupta PB, Fillmore CM, Jiang G, et al (2011). Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell, 146, 633-44. DOI ScienceOn |
36 | Han ZB, Ren H, Zhao H, et al (2008). Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis, 29, 1853-61. DOI ScienceOn |
37 | Harris AL (2002). Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer, 2, 38-47. DOI ScienceOn |
38 | Harris AL, Hochhauser D (1992). Mechanisms of multidrug resistance in cancer treatment. Acta Oncol, 31, 205-13. DOI |
39 | Heppner GH (1984). Tumor heterogeneity. Cancer Res, 44, 2259-65. |
40 | Henrique D, Hirsinger E, Adam J, et al (1997). Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Curr Biol, 7, 661-70. DOI ScienceOn |
41 | Hoey T, Yen WC, Axelrod F, et al (2009). DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell, 5, 168-77. DOI ScienceOn |
42 | Jain M, Arvanitis C, Chu K, et al (2002). Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science, 297, 102-4. DOI ScienceOn |
43 | Jaiswal S, Traver D, Miyamoto T, et al (2003). Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci USA, 100, 10002-7. DOI ScienceOn |
44 | Jo M, Kim TH, Seol DW, et al (2000). Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med, 6, 564-7. DOI ScienceOn |
45 | Karnoub AE, Dash AB, Vo AP, et al (2007). Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature, 449, 557-63. DOI ScienceOn |
46 | Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A (2007). Tumor growth need not be driven by rare cancer stem cells. Science, 317, 337. DOI ScienceOn |
47 | Khakoo AY, Pati S, Anderson SA, et al (2006). Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med, 203, 1235-47 DOI ScienceOn |
48 | Kim K, Lu Z, Hay ED (2002). Direct evidence for a role of betacatenin/LEF-1 signaling pathway in induction of EMT. Cell Biol Int, 26, 463-76. DOI ScienceOn |
49 | Kintner C (1992). Molecular bases of early neural development in Xenopus embryos. Annu Rev Neurosci, 15, 251-84. DOI ScienceOn |
50 | Kim SM, Oh JH, Park SA, et al (2010). Irradiation enhances the tumor tropism and therapeutic potential of tumor necrosis factor-related apoptosis-inducing ligand-secreting human umbilical cord blood-derived mesenchymal stem cells in glioma therapy. Stem Cells, 28, 2217-28. DOI ScienceOn |
51 | Klopocki E, Kristiansen G, Wild PJ, et al (2004). Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. Int J Oncol, 25, 641-9. |
52 | Klopp AH, Spaeth EL, Dembinski JL, et al (2007). Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. Cancer Res, 67, 11687-95. DOI ScienceOn |
53 | Knudson AG, Strong LC, Anderson DE (1973). Heredity and cancer in man. Prog Med Genet, 9, 113-58. |
54 | Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L (2006). Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses. Mol Cancer Ther, 5, 755-66. DOI ScienceOn |
55 | Lehmann BD, Bauer JA, Chen X, et al (2011). Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest, 121, 2750-67. DOI ScienceOn |
56 | Leong KG, Karsan A (2006). Recent insights into the role of Notch signaling in tumorigenesis. Blood, 107, 2223-33. DOI ScienceOn |
57 | Li C, Heidt DG, Dalerba P, et al (2007) Identification of pancreatic cancer stem cells. Cancer Res, 67, 1030-7. DOI ScienceOn |
58 | Li L, Clevers H (2010) Coexistence of quiescent and active adult stem cells in mammals. Science, 327, 542-5 DOI ScienceOn |
59 | Li YC, Fung KP, Kwok TT, et al (2002). Mitochondrial targeting drug lonidamine triggered apoptosis in doxorubicin-resistant HepG2 cells. Life Sci, 71, 2729-40. DOI ScienceOn |
60 | Li X, Lewis MT, Huang J, et al (2008). Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst, 100, 672-9. DOI ScienceOn |
61 | Liebner S, Cattelino A, Gallini R, et al (2004). Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse. J Cell Biol, 166, 359-67. DOI ScienceOn |
62 | Lin SY, Xia W, Wang JC, et al (2000). Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA, 97, 4262-6. DOI ScienceOn |
63 | Lindeman GJ, Visvader JE (2010). Insights into the cell of origin in breast cancer and breast cancer stem cells. Asia Pac J Clin Oncol, 6, 89-97. DOI ScienceOn |
64 | Liu S, Dontu G, Mantle ID, et al (2006). Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res, 66, 6063-71. DOI ScienceOn |
65 | Luistro L, He W, Smith M, et al (2009). Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties. Cancer Res, 69, 7672-80. DOI ScienceOn |
66 | Madjd Z, Ramezani B, Molanae S, Asadi-Lari M (2012). High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas. Asian Pac J Cancer Prev, 13, 2973-8. DOI ScienceOn |
67 | Massard C, Deutsch E, Soria JC (2006) Tumour stem celltargeted treatment: elimination or differentiation. Ann Oncol, 17, 1620-4. DOI ScienceOn |
68 | Morrison SJ, Qian D, Jerabek L, et al (2002). A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol, 168, 635-42. DOI |
69 | Menon LG, Picinich S, Koneru R, et al (2007). Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells. Stem Cells, 25, 520-8. DOI ScienceOn |
70 | Milane L, Duan Z, Amiji M (2011). Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer. PLoS One, 6, 24075. DOI |
71 | Muller T, Bain G, Wang X, Papkoff J (2002). Regulation of epithelial cell migration and tumor formation by beta-catenin signaling. Exp Cell Res, 280, 119-33. DOI ScienceOn |
72 | Nakamizo A, Marini F, Amano T, et al (2005). Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res, 65, 3307-18. |
73 | Nakshatri H (2010). Radiation resistance in breast cancer: are CD44+/CD24-/proteosome low/PKH26+ cells to blame? Breast Cancer Res, 12, 105. DOI ScienceOn |
74 | O'Brien CA, Pollett A, Gallinger S, Dick JE (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature, 445, 106-10. DOI ScienceOn |
75 | Orian-Rousseau V (2010) CD44, a therapeutic target for metastasising tumours. Eur J Cancer, 46, 1271-7. DOI ScienceOn |
76 | Ozawa K, Sato K, Oh I, et al (2008). Cell and gene therapy using mesenchymal stem cells (MSCs). J Autoimmun, 30, 121-7. DOI ScienceOn |
77 | Park SY, Lee HE, Li H, et al (2010). Heterogeneity for stem cellrelated markers according to tumor subtype and histologic stage in breast cancer. Clin Cancer Res, 16, 876-87 DOI |
78 | Prince ME, Sivanandan R, Kaczorowski A, et al (2007). Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA, 104, 973-8 DOI ScienceOn |
79 | Parkin DM, Bray F, Ferlay J, Pisani P (2001). Estimating the world cancer burden: Globocan 2000. Int J Cancer, 94, 153-6. DOI ScienceOn |
80 | Polakis P (2000). Wnt signaling and cancer. Genes Dev, 14, 1837-51. |
81 | Quintana E, Shackleton M, Sabel MS, et al (2008). Efficient tumour formation by single human melanoma cells. Nature, 456, 593-8. DOI ScienceOn |
82 | Ratajczak MZ (2005). Cancer stem cells--normal stem cells "Jedi" that went over to the "dark side". Folia Histochem Cytobiol, 43, 175-81. |
83 | Ravagnan L, Marzo I, Costantini P, et al (1999). Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore. Oncogene, 18, 2537-46. DOI |
84 | Resetkova E, Reis-Filho JS, Jain RK, et al (2010). Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. Breast Cancer Res Treat, 123, 97-108. DOI |
85 | Reya T, Duncan AW, Ailles L, et al (2003). A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature, 423, 409-14. DOI ScienceOn |
86 | Reya T, Morrison SJ, Clarke MF, Weissman IL (2001). Stem cells, cancer, and cancer stem cells. Nature, 414, 105-11. DOI ScienceOn |
87 | Robarge KD, Brunton SA, Castanedo GM, et al (2009). GDC-0449-a potent inhibitor of the hedgehog pathway. Bioorg Med Chem Lett, 19, 5576-81. DOI ScienceOn |
88 | Roukos DH, Murray S, Briasoulis E (2007). Molecular genetic tools shape a roadmap towards a more accurate prognostic prediction and personalized management of cancer. Cancer Biol Ther, 6, 308-12. DOI |
89 | Schultz LB, Weber BL (1999). Recent advances in breast cancer biology. Curr Opin Oncol, 11, 429-34. DOI |
90 | Ruiz I, Altaba A (1999). Gli proteins and Hedgehog signaling: development and cancer. Trends Genet, 15, 418-25. DOI ScienceOn |
91 | Sell S, Pierce GB (1994). Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Lab Invest, 70, 6-22. |
92 | Semenza GL (2003). Targeting HIF-1 for cancer therapy. Nat Rev Cancer, 3, 721-32. DOI ScienceOn |
93 | Semenza GL (2008). Hypoxia-inducible factor 1 and cancer pathogenesis. IUBMB Life, 60, 591-7. DOI ScienceOn |
94 | Shackleton M, Quintana E, Fearon ER, Morrison SJ (2009) Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell, 138, 822-9. DOI ScienceOn |
95 | Singh SK, Clarke ID, Terasaki M, et al (2003). Identification of a cancer stem cell in human brain tumors. Cancer Res, 63, 5821-8. |
96 | Snippert HJ, Haegebarth A, Kasper M, et al (2010). Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science, 327, 1385-9. DOI ScienceOn |
97 | Soltanian S, Matin MM (2011). Cancer stem cells and cancer therapy. Tumour Biol, 32, 425-40. DOI ScienceOn |
98 | Spaeth E, Klopp A, Dembinski J, Andreeff M, Marini F (2008). Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells. Gene Ther, 15, 730-8. DOI ScienceOn |
99 | Stockler M, Wilcken NR, Ghersi D, Simes RJ (2000). Systematic reviews of chemotherapy and endocrine therapy in metastatic breast cancer. Cancer Treat Rev, 26, 151-68. DOI ScienceOn |
100 | Studeny M, Marini FC, Dembinski JL, et al (2004). Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. J Natl Cancer Inst, 96, 1593-603. DOI ScienceOn |
101 | Thiery JP, Acloque H, Huang RY, Nieto MA (2009). Epithelialmesenchymal transitions in development and disease. Cell, 139, 871-90. DOI ScienceOn |
102 | Ueno NT, de Souza JA, Booser D, et al (2009). Pilot study of targeted skeletal radiation therapy for bone-only metastatic breast cancer. Clin Breast Cancer, 9, 173-7. DOI ScienceOn |
103 | Viens P, Tarpin C, Roche H, Bertucci F (2010) Systemic therapy of inflammatory breast cancer from high-dose chemotherapy to targeted therapies: the French experience. Cancer, 116, 2829-36. DOI ScienceOn |
104 | Visvader JE, Lindeman GJ (2008). Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer, 8, 755-68. DOI ScienceOn |
105 | Vlashi E, Kim K, Lagadec C, et al (2009). In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst, 101, 350-9. DOI ScienceOn |
106 | Wechsler-Reya RJ, Scott MP (1999). Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron, 22, 103-14. DOI ScienceOn |
107 | Weissman IL (2000). Stem cells: units of development, units of regeneration, and units in evolution. Cell, 100, 157-68. DOI ScienceOn |
108 | Wicha MS, Liu S, Dontu G (2006). Cancer stem cells: an old idea--a paradigm shift. Cancer Res, 66, 1883-90. DOI ScienceOn |
109 | Wong SC, Lo SF, Lee KC, et al (2002). Expression of frizzledrelated protein and Wnt-signalling molecules in invasive human breast tumours. J Pathol, 196, 145-53. DOI ScienceOn |
110 | Woodward WA, Chen MS, Behbod F, et al (2007). WNT/betacatenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci USA, 104, 618-23. DOI ScienceOn |
111 | Yague E, Arance A, Kubitza L, et al (2007). Ability to acquire drug resistance arises early during the tumorigenesis process. Cancer Res, 67, 1130-7. DOI ScienceOn |
112 | Yu F, Yao H, Zhu P, et al (2007). let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell, 131, 1109-23. DOI ScienceOn |
113 | Yuan Z, Goetz JA, Singh S, et al (2007). Frequent requirement of hedgehog signaling in non-small cell lung carcinoma. Oncogene, 26, 1046-55. DOI ScienceOn |
114 | Zhang Y, Kalderon D (2001). Hedgehog acts as a somatic stem cell factor in the Drosophila ovary. Nature, 410, 599-604. DOI ScienceOn |
115 | Zhu AJ, Watt FM (1999). beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. Development, 126, 2285-98. |
116 | Zielske SP, Livant DL, Lawrence TS (2009). Radiation increases invasion of gene-modified mesenchymal stem cells into tumors. Int J Radiat Oncol Biol Phys, 75, 843-53. DOI ScienceOn |