• Archives of Pharmacal Research
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• 제19권4호
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• pp.275-279
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• 1996

To study the functional roles of dopamine receptors, we decided to raise antibodies against these proteins. To make antigen, we expressed the whole 3rd cytoplasmic loop of dopamine receptors in a fusion protein with glutathione-S-transferase (GST). $For D_2\; and\; D_3$ receptors, it was successful to express and purify fusion proteins for the whole 3rd cytoplasmic loops. However, we could not express the fusion protein for the whole 3rd cytoplasmic loop of $D_4$ dopamine receptor in the bacteria. To study the causes that prevent the bacterial expression of the GST-fusion protein of the 3rd cytoplasmic loop of $D_4$ dopamine receptor, we conducted more detailed studies on $D_4$ dopamine receptor. To locate the region which prevents bacterial expression, we made sequential constructs in the 3rd cytoplasmic loop decreasing the size step by step, and confirmed their expressions in the SDS PAGE. It was found that certain regions of 3rd cytoplasmic loop of $D_4$ dopamine receptor, located in N-terminal side of the 3rd cytoplasmic loop of $D_4$ dopamine receptor suppress the bacterial expression of fusion protein.

• Journal of Astronomy and Space Sciences
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• 제20권4호
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• pp.359-364
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• 2003

In this paper, we present multi-sensor data fusion for telematics application. Successful telematics can be realized through the integration of navigation and spatial information. The well-determined acquisition of vehicle's position plays a vital role in application service. The development of GPS is used to provide the navigation data, but the performance is limited in areas where poor satellite visibility environment exists. Hence, multi-sensor fusion including IMU (Inertial Measurement Unit), GPS(Global Positioning System), and DMI (Distance Measurement Indicator) is required to provide the vehicle's position to service provider and driver behind the wheel. The multi-sensor fusion is implemented via algorithm based on Kalman filtering technique. Navigation accuracy can be enhanced using this filtering approach. For the verification of fusion approach, land vehicle test was performed and the results were discussed. Results showed that the horizontal position errors were suppressed around 1 meter level accuracy under simulated non-GPS availability environment. Under normal GPS environment, the horizontal position errors were under 40㎝ in curve trajectory and 27㎝ in linear trajectory, which are definitely depending on vehicular dynamics.

• Journal of Korean Neurosurgical Society
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• 제45권4호
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• pp.213-218
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• 2009

Objective : This study is a retrospective clinical study over more than 4 years of follow up to understand the mechanism of load sharing across the graft-bone interface in the static locking plate (SLP) fixation compared with non-locking plate (NLP). Methods : Orion locking plates and Top non-locking plates were used for SLP fixation in 29 patients and NLP fixation in 24 patients, respectively. Successful interbody fusion was estimated by dynamic X-ray films. The checking parameters were as follows : screw angle (SA) between upper and lower screw, anterior and posterior height of fusion segment between upper and lower endplate (AH & PH), and upper and lower distance from vertebral endplate to the end of plate (UD & LD). Each follow-up value of AH and PH were compared to initial values. Contributions of upper and lower collapse to whole segment collapse were estimated. Results : Successful intervertebral bone fusion rate was 100% in the SLP group and 92% in the NLP group. The follow-up mean value of SA in SLP group was not significantly changed compared with initial value, but follow-up mean value of SA in NLP group decreased more than those in SLP group (p=0.0067). Statistical analysis did not show a significant difference in the change in AH and PH between SLP and NLP groups (p>0.05). Follow-up AH of NLP group showed more collapse than PH of same group (p=0.04). The upper portion of the vertebral body collapsed more than the lower portion in the SLP fixation (p=0.00058). Conclusion : The fused segments with SLP had successful bone fusion without change in initial screw angle, which was not observed in NLP fixation. It suggests that there was enough load sharing across bone-graft interface in SLP fixation.

• 한국위성정보통신학회논문지
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• 제12권3호
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• pp.15-21
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• 2017

2012년 5월 다목적실용위성 KOMPSAT-3 발사 성공 이후, 2013년 8월 KOMPSAT-5, 2015년 3월 KOMPSAT-3A의 발사 성공으로 국내는 광학, 레이더, 열적외선 센서를 통합 운영할 수 있게 되었으며, 각 센서들의 특성을 융합 활용할 수 있는 기반을 마련하였다. 단일 센서가 가지고 있는 활용의 적용 범위나 산출물 정확도에 한계점을 극복하고자 다중 센서들의 장점을 취하고 단점은 상호 보완하는 다종센서간 영상융합기술이 대두하게 되었다. 본 논문에서는 다목적실용위성 군을 활용한 영상 융합 및 고부가 산출물 생성을 위한 소프트웨어(InFusion) 개발에 대하여 소개하고자 한다. 먼저 각 센서들의 특징 설명과 융합 소프트웨어 개발의 필요성에 대하여 기술하고, 개발 전과정에 대하여 상세히 설명하고자 한다. 국내외 다목적실용위성 군의 자료 활용성을 증대시키고 고부가 제품생성을 통한 국내 소프트웨어의 우수성을 알리는 계기가 되고자 한다.

• 한국정보통신학회논문지
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• 제18권5호
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• pp.1034-1041
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• 2014

본 논문은 능동카메라가 장착된 이동로봇의 장애물 회피를 위한 퍼지추론방법 제시하였다. 영상센서를 이용하여 상황적 판단에 근거한 명령융합을 사용하여 미지의 환경에서의 목적지까지의 지능적인 탐색을 수행하도록 하였다. 본 연구를 검증하기 위하여 환경모델과 센서데이터에 기반 한 이동로봇의 경로생성을 위한 물리적 센서융합을 시도하지 않고, 환경에 따른 각각의 로봇의 주행행동을 제어하기 위한 명령융합 적용하였다. 주행을 위한 전략으로는 목적지 접근과 장애물 회피를 수행할 수 있도록 퍼지규칙 조합을 통해 판단하도록 수행하였다. 제안한 방법을 검증하기 위하여 영상데이터를 사용한 성공적인 주행 실험 결과를 제시하였다.

• 한국초전도ㆍ저온공학회논문지
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• 제18권3호
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• pp.10-20
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• 2016

The Cable-In-Conduit-Conductor (CICC) for the ITER tokamak Central Solenoid (CS) has undergone design change since the first prototype conductor sample was tested in 2010. After tests showed that the performance of initial conductor samples degraded rapidly without stabilization, an alternate design with shorter sub-cable twist pitches was tested and discovered to satisfy performance requirements, namely that the minimum current sharing temperature ($T_{cs}$) remained above a given limit under DC bias. With consistent successful performance of ITER CS conductor CICC samples using the alternate design, an attempt is made here to revisit the internal electromagnetic properties of the CICC cable design to identify any correlation with conductor performance. Results of this study suggest that there may be a simple link between the $Nb_3Sn$ CICC internal self-field and its $T_{cs}$ performance. The study also suggests that an optimization process should exist that can further improve the performance of $Nb_3Sn$ based CICC.

• Bulletin of the Korean Chemical Society
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• 제26권9호
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• pp.1381-1384
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• 2005

Surface modification of tridimensional cubic mesoporous silica, SBA-16, was investigated with pendant arm functionalized cobalt diaminosarcophagine (diAMsar) cage complex which covalently grafted onto the silica surface through the silication with sylanol group. The spectroscopic results showed that the mesoporous structure was preserved under the $[Co(diAMsar)]^{3+}$ grafting reaction condition. Successful grafting prevented the cobalt diAMsar cage from leaching out from the SBA-16 support.

• 한국정밀공학회지
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• 제31권5호
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• pp.441-449
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• 2014

Thermoplastic fusion bonding is widely used to seal polymer microfluidic devices and optimal bonding protocol is required to obtain a successful bonding, strong bonding force without channel deformation. Besides, UV modification of the PMMA (poly-methyl methacrylate) is commonly used for chemical or biological application before the bonding process. However, study of thermal bonding for the UV modified PMMA was not reported yet. Unlike pristine PMMA, the optimal bonding parameters of the UV modified PMMA were $103^{\circ}C$, 71 kPa, and 35 minutes. A very low aspect ratio micro channel (AR=1:100, $20{\mu}m$ depth and $2000{\mu}m$ width) was successfully bonded (over 95%, n>100). Moreover, thermal bonding of multi stack PMMA chips was successfully demonstrated in this study. The results may applicable to fabricate a complex 3 dimensional microchannel networks.

• 한국측량학회지
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• 제30권1호
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• pp.75-86
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• 2012

SAR는 기상상태와 태양고도 제약을 받지 않고 영상을 취득할 수 있는 장점을 갖지만 광학영상에 비해 시각적 가독성이 떨어지는 단점을 갖는다. 광학영상의 다중분광정보를 융합하여 SAR 영상의 가독성을 향상시키기 위한 다중센서 융합기술에 대한 관심이 증대되고 있다. 본 연구에서는 고속 퓨리에 변환을 통한 고주파 정보 추출 및 이상치 제거과정을 통해 SAR 영상의 공간적 세밀함과 다중분광영상의 분광정보를 유지할 수 있는 새로운 다중센서 융합기술을 제안하였다. 실험데이터로는 KOMPSAT-5호와 동일한 고해상도 X-band SAR 시스템을 장착한 TerraSAR-X 영상과 KOMPSAT-2호의 다중분광영상을 사용하였다. 제안기법의 효용성을 평가하기 위해 기존에 위성영상융합에 많이 사용된 융합기법과의 시각적/정량적 비교평가를 수행하였다. 실험 결과 기존 영상융합알고리즘에 비해 분광정보 보존측면에서 보다 향상된 결과를 보임을 확인할 수 있었다.

• Journal of Korean Neurosurgical Society
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• 제30권12호
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• pp.1369-1374
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• 2001

Objectives : The rates of pseudarthrosis for two- and three level fusion have been reported to be 17-63 and 50% without anterior cervical plating. The purpose of this study is to assess the effects of anterior cervical plating in the treatment of multilevel degenerative cervical disease such mostly the additional risks associated with hardware implants and its benefits, fusion rate and radiographic results, and clinical outcomes. Methods : Forty-seven patients who underwent operations between 1993 and 1997 were retrospectively reviewed. The technique for operation was same for both groups(Smith Robinson with autologous iliac bone graft). Group I consisted of 35 consecutive patients treated with anterior cervical decompression and fusion with anterior cervical plate fixation. Group II consisted of 12 consecutive patients treated without plate fixation. We compared clinical outcomes by Prolo score, radiographic results in the rate of fusion, cervical lordosis by Gore angle, disc height by Farfan method, and surgical complications between two groups. Results : The favorable clinical outcomes(excellent and good) by Prolo score were observed with the use of anterior cervical plate fixation(89% vs 75%). The successful fusion rate of multilevel cervical fusion was as seen with anterior cervical plate fixation(97% vs 75%). The overall graft complication rate in multilevel fusions was decreased, with anterior cervical plate fixation, and the hardware related complications were relatively minimal without serious consequences. Conclusion : Anterior cervical plate fixation in the treatment of multilevel cervical disorders is an effective stabilizing method which provides increased bony fusion rate, decreased graft complications, maintained cervical lordosis, early mobilization of the these patients without serious hardware related complications.