• Title/Summary/Keyword: Sub-Strategies

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Anti-HIV-1 Activity of Gelatin Hydrolysate Derived from Alaska Pollack Theragra chalcogramma Skin (명태(Theragra chalcogramma) 껍질 유래 젤라틴 가수분해물의 항 HIV-1 효능)

  • Park, Sun-Joo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.5
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    • pp.594-599
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    • 2016
  • Infection with HIV (Human immunodeficiency virus), over time, develops into acquired immunodeficiency syndrome (AIDS). The development of non-toxic and effective anti-HIV drugs is one of the most promising strategies for the treatment of AIDS. In this study, we investigated the anti-HIV-1 activity of gelatin hydrolysates from Alaska pollack skin. Gelatin hydrolysates were prepared using four enzymes (alcalase, flavourzyme, neutrase, and pronase E). Among these, the pronase E gelatin hydrolysate was found to inhibit HIV-1 infection in the human T cell-line MT4. It exhibited inhibitory activity on HIV-1IIIB-induced cell lysis, reverse transcriptase activity, and viral p24 production at noncytotoxic concentrations. Moreover, it decreased the activation of matrix metalloproteinase-2 (MMP-2) in vitro. Because HIV infection-induced activation of MMP-2 can accelerate collagen resolution and collapse of the immune system, pronase E gelatin hydrolysate might prevent the activation of MMP-2 in cells, resulting in collagen stabilization and immune cell homeostasis consistent with anti-HIV activation. These results suggest that pronase E gelatin hydrolysate could potentially be incorporated into a novel therapeutic agent for HIV/AIDS patients.

Developing a Basic Framework for the Korean National Collection Policy (국가장서개발정책 기본모형 연구)

  • Chang, Hye-Rhan;Hong, Hyun-Jin;Noh, Young-Hee;Oh, Eui-Kyung
    • Journal of the Korean Society for Library and Information Science
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    • v.43 no.4
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    • pp.193-215
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    • 2009
  • A more sophisticated library collection policy is required due to the changing information environment. Both traditional resources and diversified networked information resources are increasing continuously. The National Library of Korea should construct a systematic collection development policy in order to fulfill its mission. The purpose of this study is to develop a basic framework that is intended to improve the coverage of national collection. Examining previous studies and the national collection development policies of major advanced countries, a model consisting of four sub-models has been proposed. It includes hybrid collection, cooperative linking collection, collection evaluation, and a collection policy statement. Details of the sub-models and strategies are described.

The Current Status and Tasks of Future Directions in Korean Society of Sport Biomechanics[1] (한국운동역학회 현황과 발전방향 과제[1])

  • Kim, Eui-Hwan
    • Korean Journal of Applied Biomechanics
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    • v.16 no.2
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    • pp.175-192
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    • 2006
  • The purpose of this study was to analyze the current status and suggest tasks of future directions for development of the Korean Society of Sport Biomechanics(KSSB). KSSB was established in the 22th of Oct.,1988. It is one of the great National Society recognized by the Korean Research Foundation, and consists of almost 350 members over national Sport Biomechanists. Two roles-functions of KSSB are as follows; one is an Independent Society by KSSB, the other is a sub-Society under Korean Alliance for Health, Physical Education, Recreation and Dance(KAHPERD) run by 15 sub-Societies. The 2 great strategies toward all over the world of KSSB were Localization and Globalization. The grand four projects of KSSB in $2005{\sim}2006yrs$ are as followers: 1) The rationalization of organization-operating and decentralization, 2) The international levels of society, 3) The internationalizaton of quality of Korean Journal of Sport Biomechanics, and 4) The presentation award by quarterly and double-movements of members of KSSB. The tasks of future direction for development of KSSB are as followers : The localization and globalization of KSSB( see above as figure 4, table 12, 13, 14).

Evaluation of Implementation Alternatives of the Mass Customization in Health Food Company (건강기능식품 사례를 통한 대량 맞춤생산 도입 대안 비교 평가 연구)

  • Lee, Hyun-Chan;Jeon, Seong-Jae
    • Korean Journal of Computational Design and Engineering
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    • v.14 no.3
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    • pp.186-196
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    • 2009
  • Mass customization (MC) is a business practice that aims to provide customers with customized products and services at near mass production efficiency. To achieve the aim, a number of methods to implementing MC are proposed. However, most of them require changes in entire process of the company, which make companies hesitate to implement MC even if it is essential to survive. In this paper, we proposed alternatives to partially implement MC for quick adaptation of MC. The base line assumption is not to change the production lines. The pros and cons of alternatives are given by qualitative and quantitative evaluation. Especially, by giving radar chart analysis of the quantitative measures, we give insight on the changes in the business performance measures, such as time to market and cost. Proposed alternatives are based on sub-processes such as purchasing raw materials, production process changes and packaging for efficient logistics. In this way, companies are able to provide customized products with small changing of the current manufacturing system. The process and benefit of the proposed strategy is verified by real world cases of a Korean health food company.

Effects of Strategies to Encourage Modulation of Overexcitability on the Task Commitment and Creative Personality of Elementary Scientific Gifted (과흥분성 조절 전략을 적용한 초등 과학 영재교육 프로그램이 초등과학 영재의 과제 집착력 및 창의적 인성에 미치는 영향)

  • Moon, Ji-Young;Bae, Jinho;So, Keum-Hyun
    • Journal of Korean Elementary Science Education
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    • v.33 no.3
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    • pp.536-548
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    • 2014
  • The purpose of this study was to develop a science gifted education program as a strategy for modulating gifted children's overexcitabilities and to examine the effect of such program on task commitment and creative personality. The results of this study were as follows. First, science gifted education program which modulated gifted children's overexcitabilities showed significant effect on the improvement of task commitment. Looking at sub domains, significant results were obtained at self-regulation. Second, science gifted education program which modulated gifted children's overexcitabilities showed significant effect on the improvement of creative personality. Looking at sub domains, significant results were obtained at the self-conviction and humors. Third, students who experienced the classes showed affirmative responses that the new teaching method was interesting and helpful. Looking at the above results, science gifted education program which modulated gifted children's overexcitabilities can be considered as effective for improving task commitment and creative personality of elementary scientific gifted students.

A Decomposition Approach for Fixed Channel Assignment Problems in Large-Scale Cellular Networks

  • Jin, Ming-Hui;Wu, Eric Hsiao-Kuang;Horng, Jorng-Tzong
    • Journal of Communications and Networks
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    • v.5 no.1
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    • pp.43-54
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    • 2003
  • Due to insufficient available bandwidth resources and the continuously growing demand for cellular communication services, the channel assignment problem has become increasingly important. To trace the optimal assignment, several heuristic strategies have been proposed. So far, most of them focus on the small-scale systems containing no more than 25 cells and they use an anachronistic cost model, which does not satisfy the requirements ity. Solving the small-scale channel assignment problems could not be applied into existing large scale cellular networks' practice. This article proposes a decomposition approach to solve the fixed channel assignment problem (FCAP) for large-scale cellular networks through partitioning the whole cellular network into several smaller sub-networks and then designing a sequential branch-and-bound algorithm that is made to solve the FCAP for them sequentially. The key issue of partition is to minimize the dependences of the sub-networks so that the proposed heuristics for solving smaller problems will suffer fewer constraints in searching for better assignments. The proposed algorithms perform well based on experimental results and they were applied to the Taiwan Cellular Cooperation (TCC) in ChungLi city to find better assignments for its network.

Review of Creativity Development Research Approaches in the Korean Engineering Education (국내 공학교육에서의 창의성 연구 동향과 발전 과제)

  • Lim, Cheolil;Kim, Sungwook;Han, Hyeongjong;Seo, Seungil
    • Journal of Engineering Education Research
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    • v.17 no.5
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    • pp.33-40
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    • 2014
  • This study aimed to analyze the current trends and future issues of the creativity development research in the Korean engineering education. The analysis led to categorizing the previous research topics into the following five domains: (i)systems and media (ii)instructional strategies and methodologies (iii)curriculum (iv)evaluation and (v) learner characteristics. The analysis further deduced more detailed sub-domains from each of the five domains. In addition, this study investigated publication frequencies of each domain and sub-domains and grasped specific flows of past research topics. Finally, based upon the analysis, this study drew implications and ramifications for creativity development studies in the Korean engineering education, elucidated future issues and refined upcoming research agendas. It is hoped that this research will articulate the present status of the studies that deal with creative education catering to engineering students and help set paths for future research.

Examination of excess electricity generation patterns in South Korea under the renewable initiative for 2030

  • Kim, Philseo;Cho, So-Bin;Yim, Man-Sung
    • Nuclear Engineering and Technology
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    • v.54 no.8
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    • pp.2883-2897
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    • 2022
  • According to the Renewable Energy 3020 Implementation Plan announced in 2017 by the South Korean government, the electricity share of renewable energy will be expanded to 20% of the total electricity generation by 2030. Given the intermittency of electricity generation from renewable energy, realization of such a plan presents challenges to managing South Korea's isolated national electric grid and implies potentially large excess electricity generation in certain situations. The purpose of this study is: 1) to develop a model to accurately simulate the effects of excess electricity generation from renewables which would arise during the transition, and 2) to propose strategies to manage excess electricity generation through effective utilization of domestic electricity generating capabilities. Our results show that in periods of greater PV and wind power, namely the spring and fall seasons, the frequency of excess electricity generation increases, while electricity demand decreases. This being the case, flexible operation of coal and nuclear power plants along with LNG and pumped-storage hydroelectricity can be used to counterbalance the excess electricity generation from renewables. In addition, nuclear energy plays an important role in reducing CO2 emissions and electricity costs unlike the fossil fuel-based generation sources outlined in the 8th Basic Plan.

Perception in the MZ Generation's Untact Era on Physical Consciousness and Cosmetological Management Behavior (MZ세대의 언택트 시대 지각이 신체의식과 뷰티관리행동에 미치는 영향)

  • Na, Yunyoung
    • Fashion & Textile Research Journal
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    • v.24 no.5
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    • pp.628-635
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    • 2022
  • This study sought to investigate the relationship between perception, body awareness, and beauty management behavior in the untact era in their MZ generation's, and as a result of the study, it was confirmed that there is a causal relationship between variables. For the empirical analysis of the study, a survey was conducted online(Google questionnaire) in Seoul/Gyeonggi area from June 7 to 26, 2021. Of the 548 questionnaires, 512, excluding 36, were analyzed using SPSS V.21.0. Among the sub-factors of perception in the untact era, it was confirmed that the social environment perception and human relationship perception are key factors that negatively affect body consciousness and beauty management behavior, and so does self-awareness(p<.05). Next, it was confirmed that, among the sub-factors of body consciousness, appearance management awareness and appearance/body care effort were key factors that positively affected beauty management behavior, and that appearance confidence was also an important factor that positively affected beauty management behavior(p<.05). Therefore, through this study, we intend to provide basic data for product development, programs, and marketing strategies that can cope with changes in the beauty consumption market in preparation for the post-COVID era.

Fabrication of Nitrogen Self-Doped Porous Carbons from Melamine Foam for Supercapacitors (슈퍼커패시터용 멜라민 폼으로부터 질소가 자가 도핑된 다공성 탄소 재료의 제조)

  • Lee, Byoung-Min;Chang, Hyeong-Seok;Choi, Jae-Hak;Hong, Sung-Kwon
    • Korean Journal of Materials Research
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    • v.31 no.5
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    • pp.264-271
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    • 2021
  • Porous carbons have been widely used as electrode material for supercapacitors. However, commercial porous carbons, such as activated carbons, have low electrochemical performance. Nitrogen-doping is one of the most promising strategies to improve electrochemical performance of porous carbons. In this study, nitrogen self-doped porous carbon (NPC) is prepared from melamine foam by carbonization to improve the supercapacitive performance. The prepared NPC is characterized in terms of the chemical structures and elements, morphology, pore structures, and electrochemical performance. The results of the N2 physisorption measurement, X-ray diffraction, and Raman analyses reveal that the prepared NPC has bimodal pore structures and pseudo-graphite structures with nitrogen functionality. The NPC-based electrode exhibits a gravimetric capacitance of 153 F g-1 at 1 A g-1, a rate capability of 73.2 % at 10 A g-1, and an outstanding cycling ability of 97.85 % after 10,000 cycles at 10 A g-1. Thus, the NPC prepared in this study can be applied as electrode material for high-performance supercapacitors.