• 한국엔터테인먼트산업학회논문지
• /
• 제14권1호
• /
• pp.27-39
• /
• 2020

본 연구는 노인체육지도자의 긍정심리자본이 조직성과와 직무열의 및 혁신행동에 미치는 영향을 알아보기 위하여 서울, 경기, 인천 지역의 스포츠센터 및 노인체육센터 5곳의 노인체육지도자 227명을 대상으로 연구하였으며, 다음과 같은 결과를 도출하였다. 첫째, 노인체육지도자의 긍정심리자본은 조직성과의 모든 하위요인에 유의한 영향을 미치는 것으로 나타났다. 둘째, 노인체육지도자의 긍정심리자본은 직무열의의 모든 하위요인에 유의한 영향을 미치는 것으로 나타났다. 셋째, 노인체육지도자의 긍정심리자본은 혁신행동에 유의한 영향을 미치는 것으로 나타났다. 따라서 본 연구의 결과, 긍정심리자본은 조직원들의 조직성과와 직무열의 및 혁신행동을 높여주는 중요한 변수임을 확인하였고 긍정심리자본이 노인체육지도자의 근무환경에 긍정적인 효과가 있다는 것을 입증한 데 큰 의의가 있다.

• 산업진흥연구
• /
• 제7권3호
• /
• pp.131-137
• /
• 2022

본 연구는 전화상담자들이 상담 현장에서 경험하는 직무스트레스와 심리적 소진을 감소시키기 위해 IFS 이론 근거로 프로그램을 개발하고, 그 효과를 검증하는 것이다. 9명을 사전 선정하여 요구조사를 시행한 후 프로그램 세부 활동 및 내용조직과 타당성을 검토 하였고, 전문가들에게 예비연구를 실시하여, 평가 및 수정·보완을 하여 최종 프로그램 구성하였다. 프로그램 효과검증을 위해 자발적으로 참여한 전화상담자를 대상으로 실험집단 10명, 통제집단 10명을 선정하였고, 실험집단에게 주 2회기씩 집단프로그램을 실시하여 효과 검증을 하였다. 연구 결과는 첫째, 전체 직무스트레스와 그 하위요인인 '업무과다', '어려운 내담자', '상담자에 대한 사회적 기대' 점수가 통계적으로 유의하게 감소하였다. 둘째, 심리적 소진의 하위요인인 '신체적 피로감', '비협조적 업무환경', '내담자 가치 저하', '사생활 악화'가 유의하게 감소하였다. 셋째, IFS 적용 프로그램에 따른 IFS 점수가 유의미하게 감소하였다.

• Animal Bioscience
• /
• 제36권4호
• /
• pp.671-678
• /
• 2023

Objective: Previous studies isolated the thermophilic ammonium-tolerant (TAT) bacterium Bacillus sp. TAT105 that grew in composting swine manure with the assimilation of ammonium nitrogen and reduced ammonia emissions during composting. Those studies also investigated the potential for applications of TAT105 to composting. It was observed that the concentration of TAT bacteria, phylogenetically close to TAT105, increased during composting. The objectives of this study were to identify the phylogenetic placement of these TAT bacteria and investigate their distribution in various composts. Methods: The phylogenetic placement of TAT105 was examined based on the sequence of 16S ribosomal RNA gene. The genomic DNA homology between TAT105 and the type strains of bacterial species that were phylogenetically close to TAT105 were examined by DNA-DNA hybridization. Moreover, the tolerances of these strains to NH₄Cl and NaCl were analyzed using a cultivation method. Concentrations of TAT bacteria in various composts were evaluated using an agar medium specific to TAT bacteria and polymerase chain reaction followed by restriction fragment length polymorphism analysis. Results: TAT105 was most closely related to Bacillus thermolactis and Bacillus kokeshiiformis. Many variants of these species have been detected in various environments, including composts. The type strains of these species displayed TAT characteristics that were similar to those of TAT105. Among the composts examined in this study, TAT bacteria were detected at high concentrations (10⁵ to 10⁹ colony forming units per gram of dry matter) in most of the composts made from cattle manure, swine manure, bark, and excess sludge. Conclusion: TAT bacteria comprised B. thermolactis, B. kokeshiiformis, and their phylogenetically close relatives. They were considered to be adaptable to composting of some certain materials, and a favorable target for searching for strains with some useful function that could be applied to composting of these materials.

• The Journal of Asian Finance, Economics and Business
• /
• 제9권3호
• /
• pp.265-274
• /
• 2022

MSMEs in the food and beverage industry play a critical role in the Indonesian economy since they account for the majority of the manufacturing sector's GDP. Despite its importance, it is unable to compete on a worldwide scale due to a lack of technological adoption. As a result, the purpose of this study is to look into the concerns and challenges that F&B MSMEs have when it comes to technology adoption. An online survey of 626 MSMEs and in-depth interviews as well as focus groups with diverse stakeholders from four provinces, namely West Java, East Java, South Sulawesi, and North Sumatera, provided the data for this study. To be thorough, the approach used in the study is based on the Technology, Organization, and Environment (TOE) framework. According to the findings, the majority of MSMEs use technology for marketing and sales, mainly through e-commerce. Meanwhile, for a variety of reasons, most of them continue to rely on traditional and semi-automatic technologies for production. According to the TOE framework, MSMEs lack those three parts of the technology adoption framework, particularly the environmental aspect, which is mostly due to a lack of cooperation among stakeholders. Finally, as a policy proposal, we offer a comprehensive technology adoption strategy based on the findings through an integrated MSMEs development information system including many important stakeholders.

• Genomics & Informatics
• /
• 제21권1호
• /
• pp.9.1-9.13
• /
• 2023

Matrix metalloproteinase-9 (MMP-9) is a zinc and calcium-dependent proteolytic enzyme involved in extracellular matrix degradation. Overexpression of MMP-9 has been confirmed in several disorders, including cancers, Alzheimer's disease, autoimmune diseases, cardiovascular diseases, and dental caries. Therefore, MMP-9 inhibition is recommended as a therapeutic strategy for combating various diseases. Cinnamic acid derivatives have shown therapeutic effects in different cancers, Alzheimer's disease, cardiovascular diseases, and dental caries. A computational drug discovery approach was performed to evaluate the binding affinity of selected cinnamic acid derivatives to the MMP-9 active site. The stability of docked poses for top-ranked compounds was also examined. Twelve herbal cinnamic acid derivatives were tested for possible MMP-9 inhibition using the AutoDock 4.0 tool. The stability of the docked poses for the most potent MMP-9 inhibitors was assessed by molecular dynamics (MD) in 10 nanosecond simulations. Interactions between the best MMP-9 inhibitors in this study and residues incorporated in the MMP-9 active site were studied before and after MD simulations. Cynarin, chlorogenic acid, and rosmarinic acid revealed a considerable binding affinity to the MMP-9 catalytic domain (ΔG_binding < -10 kcal/ mol). The inhibition constant value for cynarin and chlorogenic acid were calculated at the picomolar scale and assigned as the most potent MMP-9 inhibitor from the cinnamic acid derivatives. The root-mean-square deviations for cynarin and chlorogenic acid were below 2 Å in the 10 ns simulation. Cynarin, chlorogenic acid, and rosmarinic acid might be considered drug candidates for MMP-9 inhibition.

• 임상간호연구
• /
• 제29권3호
• /
• pp.271-282
• /
• 2023

Purpose: This study is a descriptive research study attempted to identify the job stress and positive psychological capital of clinical nurses and to identify the factors that impact job embeddedness. Methods: Data were collected from 115 nurses with over one year of clinical experience working at a 500-bed B General Hospital. The collected data were analyzed with the SPSS 27.0 program using frequency and percentage, mean and standard deviation, Independent t-test, One-way ANOVA, Scheffé test, Pearson's correlation coefficients, and multiple linear regression. Results: As a result of multiple regression analysis, hope among the sub-factors of positive psychological capital (β=0.48, p<.001), matters related to the work schedule (β=-0.23, p=.005) among the sub-factors of job stress, and conflict with doctor (β=0.20, p=.013) was found to have an impact on job embeddedness, and the explanatory power of this regression model was 52.0% (F=13.12, p<.001). Conclusion: It was found that the positive psychological capital of clinical nurses has a positive impact on job embeddedness. In order to increase the job embeddedness of clinical nurses, it is necessary to develop, educate, and utilize specific intervention programs that can strengthen positive psychological capital. Efforts should be needed to prepare specific strategies for nurses to recognize the importance of hope and actively utilize positive psychological capital. In addition, it is necessary to create an organization-level working environment and continuous management to reduce the job stress of clinical nurses.

• Genomics & Informatics
• /
• 제21권3호
• /
• pp.38.1-38.8
• /
• 2023

Non-small cell lung cancer (NSCLC) is an important cause of cancer-associated deaths worldwide. Therefore, the exact molecular mechanisms of NSCLC are unidentified. The present investigation aims to identify the miRNAs with predictive value in NSCLC. The two datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed miRNAs (DEmiRNA) and mRNAs (DEmRNA) were selected from the normalized data. Next, miRNA-mRNA interactions were determined. Then, co-expression network analysis was completed using the WGCNA package in R software. The co-expression network between DEmiRNAs and DEmRNAs was calculated to prioritize the miRNAs. Next, the enrichment analysis was performed for DEmiRNA and DEmRNA. Finally, the drug-gene interaction network was constructed by importing the gene list to dgidb database. A total of 3,033 differentially expressed genes and 58 DEmiRNA were recognized from two datasets. The co-expression network analysis was utilized to build a gene co- expression network. Next, four modules were selected based on the Z_summary score. In the next step, a bipartite miRNA-gene network was constructed and hub miRNAs (let-7a-2-3p, let-7d-5p, let-7b-5p, let-7a-5p, and let-7b-3p) were selected. Finally, a drug-gene network was constructed while SUNITINIB, MEDROXYPROGESTERONE ACETATE, DOFETILIDE, HALOPERIDOL, and CALCITRIOL drugs were recognized as a beneficial drug in NSCLC. The hub miRNAs and repurposed drugs may act a vital role in NSCLC progression and treatment, respectively; however, these results must validate in further clinical and experimental assessments.

• Animal Bioscience
• /
• 제37권3호
• /
• pp.405-418
• /
• 2024

In recent years, there has been a growing argument attributing the primary cause of global climate change to livestock industry, which has led to the perception that the livestock industry is synonymous with greenhouse gas (GHG) emissions. However, a closer examination of the global GHG emission by sector reveals that the energy sector is responsible for the majority, accounting for 76.2% of the total, while agriculture contributes 11.9%. According to data from the Food and Agriculture Organization of the United Nations (FAO), the total GHG emissions associate with the livestock supply chain amount to 14.5%. Within this, emissions from direct sources, such as enteric fermentation and livestock manure treatment, which are not part of the front and rear industries, represent only 7%. Although it is true that the increase in meat consumption driven by global population growth and rising incomes, has contributed to higher methane (CH₄) emissions resulting from enteric fermentation in ruminant animals, categorizing the livestock industry as the primary source of GHG emissions oversimplifies a complex issue and disregards objective data. Therefore, it may be a misleading to solely focus on the livestock sector without addressing the significant emissions from the energy sector, which is the largest contributor to GHG emissions. The top priority should be the objective and accurate measurement of GHG emissions, followed by the development and implementation of suitable reduction policies for each industrial sector with significant GHG emissions contributions.

• 대한공업교육학회지
• /
• 제39권2호
• /
• pp.101-121
• /
• 2014

이 연구는 고교 단계에서의 실전 창의형 인재 양성을 위한 NCS 기반 직업교육과 정의 모형을 개발하는 것이 목적이다. 이 연구를 효과적으로 수행하기 위해 사용한 연구 방법은 국내 외 문헌 연구, 내용 분석 연구, 사례 연구, 전문가(9명) 협의회 및 검토 자문 위원(3명)의 심층 면담 조사 방법으로 수행하였다. 또한 구안한 모형(안)의 타당도 확보를 위해 평균, 표준 편차, 내용 타당도 비율(CVR)로 분석하였다. 이 연구의 주요 개발 결과는 다음과 같다. 첫째, NCS 개발 매뉴얼과 훈련기준 활용 훈련과정 편성 매뉴얼, NCS 학습모듈 개발 매뉴얼과 사례집, NCS 연구보고서, NCS 기반 고교 단계 직업교육과정의 시범 개발 자료집과 사례 연구 분석, 국내 외 직업교육 모형 등 NCS 관련 선행 및 문헌 연구를 토대로 실전 창의형 인재 양성을 위한 NCS 기반 직업교육과정의 기본 모형(안)을 개발하였고 둘째, 구안한 모형(안)의 단계별 영역별 해당 하위 구성 요소 도출 자료를 토대로 전문가 심층 면담 조사 내용과 의견을 반영하여 최종 19개를 도출하였다. 즉 1단계의 영역별 하위 구성 요소로 능력단위, 능력단위정의, 능력단위요소, 수행준거, 적용범위 및 작업상황, 평가지침, 직업기초능력이고 2단계의 영역별 하위 구성 요소는 교과목명, 교과목표, 대단원명, 대단원목표, 교수 학습 방법, 평가방법, 직업기초능력이며 3단계 영역별 해당 하위 구성 요소로 NCS 기반 교과목 행렬표, NCS 기반 교과목 프로파일, NCS 기반 직업교육과정 편제표, NCS 기반 교과목 전체 구성도, NCS 기반 직업교육과정의 운영계획서를 도출하였다. 셋째, 1단계와 2단계 각각의 해당 하위 구성 요소를 3단계의 NCS 기반 교과목 프로파일과 연계 구성하여 모형(안)을 개발하였다. 넷째, 모형(안)에 대해 단계별 영역별로 타당도를 검증한 결과 평균이 4.67이고 CVR 값은 1.00으로 타당도가 매우 우수함을 알 수 있었다. 또한 해당 하위 구성 요소 도출 내용에 대한 평균이 모두 4.33 이상이며 CVR 값은 1.00으로 타당도가 매우 높았고 모형(안)의 연계 구성에 대한 평균도 모두 4.33 이상이며 CVR 값도 1.00이었다. 그리고 표준 편차는 .50 이하로 편차가 모두 작은 것으로 나타났다. 다섯째, 전문가에 의한 타당성 검증 자료와 검토 자문 위원들의 심층 면담 조사 내용을 토대로 모형(안)을 수정 보완 단계를 거쳐 고교 단계에서의 실전 창의형 인재 양성을 위한 NCS 기반 직업교육과정의 모형을 개발하였다.

• 농촌의학ㆍ지역보건
• /
• 제33권2호
• /
• pp.221-231
• /
• 2008

Abstract - Objective: This study was conducted to investigate the effect of work conditions on job stress of social workers in Seoul. Method: For this survey, a self-reported questionnaire was administrated to 1,000 social workers working in all of organization for social welfare practice in Seoul. The number of responded questionnaires was 431. Multiple linear regression analysis was used for job stress as the dependent variables and control variables. Results: The result of multiple linear regression analysis indicated that regular rest breaks had significantly effect on job stress level but long working hours did not. When regular rest breaks was guaranteed job stress of social workers significantly lowered 8.4 point. In addition standardized regression coefficients and partial R2 of regular rest breaks was the highest score among the variables. Conclusion: This study suggests that it is the most important to guarantee regular rest breaks in the work schedule in order to alleviate job stress of social workers.