• 한국수산과학회지
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• 제36권1호
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• pp.65-67
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• 2003

Flounder (Paralichthys olivaceus) fish goes through metamorphosis in the larvae phase. In this phase, it secretes much thyroid hormone to control metamorphosis. Sharp change in the environment and nutrition deficiency may cause stress in the metamorphosis phase. It leads to interfering with the development of thyroid hormone and finally inhibits the normal growth of larvae. In this study, the correlation between the change in thyroid hormones and the albinism appearance was examined by growing them with low temperature ($13^{\circ}C$) stress over the premetamorphosis stages (stage $D\~F$) of flounder metamorphosis. Albinism rate was $15\%$ in the low temperature group and $25\%$ in the control goup. $T_{4}\;and\;T_{3}$ of the control group tended to increase from stage F as larvae grew. $T_{4}$ increased 2 times compared to the control group as 72 ng/g at stage H, the increasing phae of water temperature, in the low temperature group. $T_{3}$ increased 8 times compared to the control group as 2.9 ng/g at stage E, the decreasing phase of water temperature. Therefore, it is judged that the albinism appearance of flouner is caused from the sharp increase in $T_{3}$ by the inappropriate secretion of thyroid hormone.

• 대한의생명과학회지
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• 제15권3호
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• pp.249-255
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• 2009

All living things have been developed efficient strategies to cope with external and internal environmental changes via a process termed 'homeostasis'. However, chronic prenatal maternal stress may significantly contributes to pregnancy complications by disturbing hypothalamic-pituitary-adrenal (HPA) axis and the automatic nervous system (ANS), and results in unfavorable development of the fetus. Dysregulation of these two major stress response systems lead to the increased secretion of the glucocorticoids (GCs) which are known to be essential for normal development and the maturation of the central nervous system. As Hox genes are master key regulators of the embryonic morphogenesis and cell differentiation, we aimed to determine the effects of dexamethasone, a potent synthetic glucocorticoid, on gene expression in mesenchymal stem cell C3H10T1/2. Analysis of 39 Hox genes based on reverse transcription PCR (RT-PCR) method revealed that the expression patterns of Hox genes were overall upregulated by long dexametasone treatment. These results indicate that maternal stress may have a deleterious effect on early developing embryo through the stress hormone, glucocorticoid.

• 생태와환경
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• 제53권1호
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• pp.80-90
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• 2020

In order to understand the stress responses, we measured the concentration of stress hormones by using the fresh feces of wild otters in the Gwangju stream and Seomjin river during summer and winter in 2018. We compared seasonal and regional number of spraints (=otters' feces), temperature, altitude, water width, land cover, and water quality with stress hormones. The stress hormone levels were higher in summer than in winter, and significantly different to season and region. In addition, the number of feces were different according to the season and region, and showed a negative correlation with stress hormone. This study suggested assessing stress hormones as another promising method for the analysis of status of wild otters and it will contribute to establish the management and conservation policy, especially in urban area.

• 대한치과의사협회지
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• 제54권11호
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• pp.897-906
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• 2016

Objectives: Periodontitis is multifactorial disease mainly caused by microbial community. Recently, some research has been conducted to find other possible risk factors including stress hormones related to periodontitis. Psychological stress can affect the periodontal health by a variety of biological mechanisms. This study compared the stress hormone levels in healthy subjects and patients with periodontal disease using saliva in order to investigate the association between periodontitis and stress. Methods: The human saliva was collected from 38 periodontally healthy individuals and 34 patients with chronic periodontitis under Institutional Review Board. Their age was 20-60 years ($40.3{\pm}10.45$). From these samples, determination of salivary levels of cortisol and Dehydroepiandrosterone (DHEA) performed by enzyme immunoassay kit (Salimetrics Europe, Suffolk, UK). The independent t-test and Mann-Whitney test for trend was applied using IBM SPSS statistics version 12.0 Program to analyze statistically significant differences. Results: Salivary cortisol levels of periodontitis patients were higher than those levels of healthy subjects (P < 0.001), while salivary DHEA levels of periodontitis patients were not significantly different (P = 0.431). Salivary cortisol/DHEA ratio of periodontitis patients was higher than those levels of healthy subjects (P < 0.001). Conclusions: Our study demonstrates the high levels of cortisol concentrations and cortisol/DHEA ratio in saliva of periodontitis patients than those of healthy subjects. Since cortisol levels and cortisol/DHEA ratio can be significant factors related to the severity of periodontal disease, our study would be helpful for early diagnosis and treatment of periodontal disease.

• Biomolecules & Therapeutics
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• 제22권6호
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• pp.570-576
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• 2014

Studies have demonstrated that electromagnetic waves, as the one of the most important physical factors, may alter cognitive and non-cognitive behaviors, depending on the frequency and energy. Moreover, non-ionizing radiation of low energy waves e.g. very low frequency waves could alter this phenomenon via alterations in neurotransmitters and neurohormones. In this study, short, medium, and long-term exposure to the extremely low frequency electromagnetic field (ELF-EMF) (1 and 5 Hz radiation) on behavioral, hormonal, and metabolic changes in male Wistar rats (250 g) were studied. In addition, changes in plasma concentrations for two main stress hormones, noradrenaline and adrenocorticotropic hormone (ACTH) were evaluated. ELF-EMF exposure did not alter body weight, and food and water intake. Plasma glucose level was increased and decreased in the groups which exposed to the 5 and 1Hz wave, respectively. Plasma ACTH concentration increased in both using frequencies, whereas noradrenaline concentration showed overall reduction. At last, numbers of rearing, sniffing, locomotor activity was increased in group receiving 5 Hz wave over the time. In conclusions, these data showed that the effects of 1 and 5 Hz on the hormonal, metabolic and stress-like behaviors may be different. Moreover, the influence of waves on stress system is depending on time of exposure.

• 동의신경정신과학회지
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• 제3권2호
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• pp.49-63
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• 1992

In order to study the anti-stress effect of Bunsimgieum, the changes of plasma catecholamine, aldosterone and cortisol levels were measured. In this study author gave immobilization stress to rats, and got the following results: 1. The contents of NE and EPI control group were $2.67{\pm}0.53$, $1.90{\pm}0.22\;ng/ml$, but in sample group the contents were $1.93{\pm}0.67$, $1.15{\pm}0.28\;ng/ml$. The real significance lies in thet only NE show the difference. 2. The contents of aldosterone in control group were $440.69{\pm}37.82\;Pg/ml$, but in sample group $174.64{\pm}42.41Pg/ml$ of aldosterone was measured. The difference was obvious. 3. The cortisol contents in control group were $0.17{\pm}0.03\;ug/dl$, but in sample group $0.28{\pm}0.03 \;ug/dl$ of cortisol was measured. Base on the results above, it may be concluded that Bunsimgieum is effective to prevent to prevent the changes by stress.

• 수면정신생리
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• 제6권2호
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• pp.116-125
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• 1999

Objectives: The purpose of this study is to investigate the effect of exercise load on sleep structure and stress hormone secretion during sleep. Methods: Five male physical education students were included in this study after giving their written, informed consents in the Research Institute for Sports Science at the University of Hanyang. All subjects have performed for at least 3 years in a regular aerobic exercises such as football, basketball, and running. The subjects were divided into three groups ; NOE(non-exercise), MDE(middle duration exercise), LDE(long duration excercise). MDE group maintained a total of 120 min exercise, and LDE group maintained a total of 300 min exercise by football, basketball or badminton. All subjects were acclimatized to the experimental sleep condition by spending one night under expermental conditions, including the placement of an intravenous catheter. During the subsequent night(24:00-08:00), somnopolygraphic sleep recordings were obtained, and blood for measuring growth hormone, cortisol, testosterone, and $\beta$-endorphin was collected every 120 min throughout the night. Blood samples were obtained from prominent forearm veins of subjects. Then, the samples were immediately placed in ice and centrifuged within 10 min at 3000 rpm at $4^{\circ}C$. Statistical analyses were performed using the SPSS/$PC^+$. Data were analyzed by one-way ANOVA with repeated measures. Results: No significant differences among groups were observed in sleep latency, total sleep time, stage 2 sleep, and slow wave sleep. However, daytime exercise produced significant changes in stage 1 sleep, REM sleep, stage 2 sleep latency, REM sleep latency and sleep efficiency. Stage 1 sleep, stage 2 sleep latency, and REM sleep latency significantly increased in LDE compared to those of NOE and MDE groups. But the amount of REM sleep significantly decreased in LDE. Sleep efficiency of MDE was higher than those of NOE and LDE. The blood concentrations of growth hormone, testosterone, and cortisol during night sleep were significantly lower in LDE than in NOE. $\beta$-endorphin concentrations in blood during night sleep were not different among groups. Conclusion: The daytime exercise load was significantly related to sleep structure and stress hormone secretion during night sleep. Long duration exercise showed a harmful effect on sleep structure and hormone secretion. However, middle duration exercise had a beneficial effect on sleep structure and hormone secretion during sleep.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.21-21
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• 2022

• 대한한방부인과학회지
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• 제36권2호
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• pp.1-19
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• 2023

Objectives: The purpose of this health promotion project for Korean medicine is to promote the health of climacteric women in Boeun-gun. Methods: During the project, pressure needle acupuncture treatment, herbal medicine treatment, meditation pore therapy, and health education were conducted. To evaluate the results, basic health surveys (body height, body composition test, blood pressure etc.), female hormone tests, Kupperman's index (KI), Menopause-specific quality of life questionnaire (MENQOL), and Perceived stress scales (PSS) were conducted. Results: No significant change was observed in the body composition test and blood pressure after the project. Follicle stimulating hormone (FSH) was significantly increased after the project, but Luteinizing Hormone (LH) and total estrogen levels were not significantly changed. KI and MENQOL scores significantly decreased after the project, and significantly decreased in 4 out of 11 items of KI and 3 out of 4 domains of MEMQOL. No significant change was observed in the PSS score after the project. Conclusions: From the results of this project, it can be seen that the Korean medicine health promotion project can help alleviate symptoms of climacteric syndrome and postmenopausal syndrome.

• Child Health Nursing Research
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• 제11권3호
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• pp.301-307
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• 2005

Purpose: To investigate changes in mother's stress, degree of depression and level of milk secretion hormones when the mothers provided massage to their new born babies. Method: The study was conducted with 65 women who had delivered at a convalescence institute in Incheon between Sep 25, 2003 and Feb 10, 2004. The mothers were assigned to a control group or an experimental group. Infants of mothers in the experimental group received massage from their mothers twice a day for 10 days beginning on the 4th day after delivery. The data were processed using $x^2-test$, paired t-test and repeated measures ANOVA using the SAS program. Results: The level of cortisol, a stress hormone and depression were significantly different between the two groups (p=0.01 ;p=0.02). While fur plasma prolactin level, a milk secretion hormone, there was no significant difference(p=0.14). Conclusions: When massage was provided to new-born babies the cortisol level of the mothers decreased significantly compared to the control group which did not receive the massage. As the level of depression of the control group declined as time passed while the experiment group showed no difference and there was no difference in the plasma prolactin level, further study is suggested.