• Child Health Nursing Research
• /
• 제8권1호
• /
• pp.44-54
• /
• 2002

The main purpose of this methodological study was to develop an assessment tool and intervention protocol for child and family with childhood cancer at early diagnosis stage. The assessment tool and intervention protocol was developed by extensive literature review and consultation with experts. Review of nine domestic and sixty-six international journal articles were done to identify stress, interventions, coping strategies and adjustment of children with cancer and their family. Results were as follows; First, assessment at the early diagnosis stage need to include information on patient, family, and patient/family attitude toward diagnosis and treatment. Second, intervention protocol for children with cancer includes control physical symptoms, manage the side effects of chemotherapy and diagnostic or therapeutic procedures, control emotional responses, provide support and information, assist decision-making and adjust to environment. Third, intervention protocol for family includes controlling emotional responses, provision of informations, inducing family support to patient, improving family cohesion, supporting siblings and supporting spiritual growth. In conclusion, the early diagnosis stage in cancer treatment is important for child and family since this stage greatly affects the overall adjustment of child and family to live with cancer. Therefore, pediatric nurses need to be sensitive to the need of patient/family and systematically manage their needs at this stage.

• Clinical and Experimental Reproductive Medicine
• /
• 제45권2호
• /
• pp.94-99
• /
• 2018

Objective: Prompt diagnosis and management are essential for saving the adnexal organs from infarction in cases of ovarian torsion (OT). This study aimed to determine the diagnostic significance of signal peptide, complement C1r/C1s, Uegf, and Bmp1 (CUB), and epidermal growth factor-like domain-containing protein-1 (SCUBE-1) levels in cases of OT, an emergent ischemic condition, and the relationship of SCUBE-1 with oxidative stress parameters. Methods: This prospective study was conducted among 15 OT patients and 20 age- and gravidity-matched healthy women. SCUBE-1 serum concentrations were determined by using enzyme-linked immunosorbent assays. In addition, oxidative stress was evaluated by measuring the serum levels of advanced oxidation protein products (AOPP), ferric reducing ability of plasma (FRAP), and glutathione (GSH). Results: The SCUBE-1 titers were significantly higher in the patients with OT than in the controls (p=0.008). In addition, serum FRAP and GSH levels were significantly lower in the OT patients than in the controls (p<0.001 for both). Serum AOPP levels were higher in the OT patients, but this trend was not statistically significant (p>0.05). Furthermore, there were no correlations between SCUBE-1 levels and age, gravidity, parity, cyst size, and AOPP, FRAP, or GSH levels (p>0.05). Conclusion: We believe that SCUBE-1 may be a promising biomarker for the early diagnosis of OT.

• 정신신체의학
• /
• 제4권1호
• /
• pp.124-137
• /
• 1996

As the society becomes more industrialized and modernized, we have more chances to experience a serious traumatic event. Post-traumatic stress disorder (PTSD) has 3 major categories of symptoms such as memory disturbance, hyperarousal and avoidance or numbness. I reviewed the psychobiological evidences in 3 main categories of symptoms and the biological treatment after a brief review of the epidemiology, psychosocial etiology and diagnosis of PTSD. The memory disturbance of PTSD might be developed by the potentiation of the memory pathway mediated by norepinephrine. PTSD induces HPA axis abnormality, it might also develop hippocampal dysfunction, which might contribute to the memory disturbance. The kindling effect develops desensitization, which might develop reexperiencing of the traumatic events and hyperarousal state. Chronic aroused state of locus ceruleus with resultant chronic maladaptive state of norepinephrine system, might develop hyperarousal state. Social avoidance and physical numbing state in PTSD might be caused by serotnin or opiate system. Stress induced analgesia might be developed by opiate reliesed against the acute stress. The biologic research results would help the selective treatment of PTSD.

• 대한용접접합학회:학술대회논문집
• /
• 대한용접접합학회 2005년도 춘계학술발표대회 개요집
• /
• pp.288-290
• /
• 2005

Apparent mechanical properties in structural components can be different from the initially designed values due to the formation of the residual stress in metal forming and welding. Therefore, the evaluation of residual stress has great importance in the reliability diagnosis of structural components. A nondestructive continuous indentation technique has been proposed to evaluate various strength concerning mechanical properties from the analysis of load-depth curve. In this study, quantitative residual stress estimation on API X65 welded joints for natural gas pipeline was performed by analyzing the variation of indentation loading curve by residual stress through a new proposed theoretical model.

• 동의생리병리학회지
• /
• 제24권3호
• /
• pp.525-532
• /
• 2010

Dypepsia is the most common gastrointestinal disease and mainly occurs by stress or food. According to the cause of dyspepsia, the clinical characteristics and the curative process are different in patients. The purpose of this study is to compare acute dyspepsia patients depending on food factor and stress factor. For this study, we analyzed the cause, and the symptoms of 59 acute dyspepsia patients and divided them into two groups: one group is 27 acute dyspepsia patient group caused by stress factor (stress factor group). The other group is 32 acute dyspepsia patient group caused by food factor (food factor group). In addition, we carried out HRV test and compared HRV index between two groups. There was no significant difference in past illness involved in gastrointestinal tract diseases between two groups. There were big differences in the frequency of chest discomfort, thurst, lack of appetite, and exhaustion after meals between two groups. There were many changes of tongue fur in food factor group. But there were many changes of tongue body in stress factor group. The pulse pattern is mostly wiry in stress factor group. But, The pulse pattern is mostly slippery in food factor group. HF, TP were significantly lower than food factor group in stress factor group, it means autonomic nerve system was more suppressd in stress factor group than food factor group. Food factor group improved sooner than stress factor group. This study presented the clinically different characteristics (past medical history, symptoms, tongue diagnosis, pulse pattern, curative process) of acute dyspepsia depending on food factor and stress factor. Thus, it provides the necessity of oriental medical diagnosis and treatment called pattern identification for acute dyspepsia.

• Journal of Oral Medicine and Pain
• /
• 제20권2호
• /
• pp.385-397
• /
• 1995

The purpose of this study is to document the stress symptoms (Anxiety and depression) among dental students and the difference of stress level between classes and by gender. All students in dental college, Seoul National University, in the 1995 academic year, were tested with the Spielberger's State-Trait Anxiety Inventory and Beck Depression Inventory just before the first semestral examination when the stress levels of students are expected to be the highest. 303 students answered the test. The obtained results were as follows : 1. State Anxiety inventory scores of the second-year and first-year students were significantly higher than those of the fourth -year and third-year(p(0.01), and all classes showed mean state anxiety scores more than mild. 2. Trait Anxiety inventory scores of the second-year and first-year students were significantly higher than those of the third-year and forth-year(p(0.01), and all classes showed mean Trait Anxiety scores more than mild. 3. Beck Depression inventory scores of the second -year students were significantly higher than those of the third-year and fourth-year(p(0.01), and twenty two students(7.3%) among the fourth classes showed depression symptoms. 4. In the comparison of the mean scores of the State-Trait Anxiety Inventory and Beck Depression Inventory between male and female students, State Anxiety Inventory scores of the second-year female students were significantly higher than those of the second year male students(p(0.05), and there was no significant difference elsewhere.

• 대한간호학회지
• /
• 제16권2호
• /
• pp.36-43
• /
• 1986

The main purpose of this study was to explore the effect of the stress of hospitalization on the sleep pattern. Additionaly, this study was also to demonstrate how Johnson's nursing model may be applied to as nursing process. 104 hospitalized patients on surgical and medical wards were asked to rate 49 stress producing events associated with experience of hospitalization and sleep pattern scale. Five university hospitals were used as the setting for this study. Data for the study were collected by patient interview during hospitalization, self-reports and review of charts. For the analysis of the data, the pearson's correlation analysis of covariance and regression analysis were used. The results of this study were stated as follows; 1. The mean of the hospital stress scores was 111.261(S.D.=26.160). This means that the level of the hospitalization stress is high. The mean of the sleep pattern scores was 12.204(S.D. =2.615) This means that the characteristic's of the sleep pattern is poor. 2. The relationship between the hospitalization stress and sleep pattern was statistically significant at .01 level. 3. The effect of the hospitalization stress influenced strongly on the sleep pattern after sex, trait anxiety as covariates controlled. 4. The hospitalization stress revealed a 12% pre-diction as an influenced factor for the sleep pattern. Therefore, It can he said that the hospital stress did contribute significantly to the characteristics of the sleep pattern. Johnson's model can he also said that it is useful for the the assessment and diagnosis in nursing process.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권2호
• /
• pp.641-646
• /
• 2015

Breast cancer (BC) is potentially a traumatic stressor which may be associated with negative outcomes, such as post-traumatic stress disorder (PTSD) or positive changes, such as post-traumatic growth (PTG). This study aims to identify the core issues of BC related PTSD, PTG and psychological distress by interrogating the literature in BC survivors. We have also highlighted issues related to the assessment, diagnosis and clinical management of PTSD and PTG. The authors systematically reviewed studies published from 1985 to 2014 pertaining to PTSD, psychological distress and PTG in BC survivors with particular attention paid to incidence rates and causative factors. Multiple studies intimated that women with BC have evidence of PTSD at the initial stages of diagnosis, whereas PTG develops once patients undergo treatment. Early diagnosis and treatment of PTSD/PTG is paramount from literature review but the previously mentioned relationship between PTSD and PTG in BC patients could not be verified. It is evident from the literature that a small percentage of BC patients experience PTSD, while the majority experience PTG after BC diagnosis and treatment. Future research should include prospective studies focusing on high-risk patients, causative factors and the development of psychological interventions.

• 대한토목학회논문집
• /
• 제40권2호
• /
• pp.183-189
• /
• 2020

이 논문은 인장 응력, 주변 온도 및 인가 주파수에 대한 강선의 전기적 임피던스 민감도에 관한 실험적 조사이다. 다양한 응력 수준 및 온도에 대해서, 강선의 전기적 임피던스가 자가진단 시스템에서 측정되었다. 세 가지 경우의 실험이 다양한 온도 조건, 응력 수준 및 적용 주파수에 대해서 수행되었다. 주어진 주파수에서 온도가 상승하고 응력이 감소하면 강선의 전기 임피던스가 증가한다. 실험 결과는 전기적 임피던스와 온도 사이의 상관관계가 모든 응력 수준에서 선형 관계임을 보여준다. 온도에 대한 임피던스의 감도는 응력보다 훨씬 높다는 점이 주목 된다.

• Clinical and Experimental Reproductive Medicine
• /
• 제42권1호
• /
• pp.1-7
• /
• 2015

Stress coping mechanisms are critical to minimize or overcome damage caused by ever changing environmental conditions. They are designed to promote cell survival. The unfolded protein response (UPR) pathway is mobilized in response to the accumulation of unfolded proteins, ultimately in order to regain endoplasmic reticulum (ER) homeostasis. Various elements of coping responses to ER stress including Perk, Ask1, Bip, Chop, Gadd34, Ire1, Atf4, Atf6, and Xbp1 have been identified and were found to be inducible in oocytes and preimplantation embryos, suggesting that, as a normal part of the cellular adaptive mechanism, these coping responses, including the UPR, play a pivotal role in the development of preimplantation embryos. As such, the UPR-associated molecules and pathways may become useful markers for the potential diagnosis of stress conditions for preimplantation embryos. After implantation, ER stress-induced coping responses become physiologically important for a normal decidual response, placentation, and early organogenesis. Attenuation of ER stress coping responses by tauroursodeoxycholate and salubrinal was effective for prevention of cell death of cultured embryos. Further elucidation of new and relevant ER stress coping responses in periimplantation embryos might contribute to a comprehensive understanding of the regulation of normal development of embryonic development and potentiation of embryonic development in vitro.