• Title/Summary/Keyword: Stereotactic

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Successful Treatment of Infantile Fibrosarcoma Spinal Metastasis by Chemotherapy and Stereotactic Hypofractionated Radiotherapy

  • Lo, Cheng-Hsiang;Cheng, Shin-Nan;Lin, Kuen-Tze;Jen, Yee-Min
    • Journal of Korean Neurosurgical Society
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    • v.54 no.6
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    • pp.528-531
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    • 2013
  • We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife$^{(R)}$ stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.

Intracranial Undifferentiated Sarcoma Arising from a Low-Grade Glioma : A Case Report and Literature Review

  • Kim, Bum-Joon;Kim, Jong-Hyun;Chung, Hung-Seob;Kwon, Taek-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.57 no.6
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    • pp.469-472
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    • 2015
  • Undifferentiated sarcomas are rarely identified in the intracranial region. A 23-year-old man was admitted with a chief complaint of headache. Initial magnetic resonance images showed signs of low-grade glioma in the frontal lobe. Stereotactic biopsy was performed, and a diagnosis of diffuse astrocytoma was confirmed. Three months later, the patient presented with a high-grade tumor as seen on imaging studies. He underwent total resection of the tumor and histopathological tests identified an undifferentiated sarcoma. The patient died eight months later due to massive tumor bleeding. To the best of our knowledge, this is the first report of undifferentiated sarcoma arising from low-grade glioma without any chemotherapy or radiotherapy.

Development of 3D Mutil-volume Visualization System for Stereotactic Surgery (뇌정위 수술계획을 위한 다원 3차원 영상가시화 시스템의 개발)

  • Choi, Jae-Jeong;Ge, Jin;Shin, Yeong-Gil
    • Proceedings of the Korean Information Science Society Conference
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    • 1998.10c
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    • pp.612-614
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    • 1998
  • 뇌정위 수술(Stereotactic Surgery)은 컴퓨터 단층영상과 자기공명 영상 같은 3차원 영상을 이용하여 뇌병변의 위치를 입체적으로 정확히 파악하여 정상 뇌에 대한 손상을 최소화하며 병변을 수술하는 기법이다. 본 논문에서는 수술 받을 환자의 컴퓨터 단층영상과 자기공명 영상 등 다양한 종류의 3차원 볼륨 데이터를 전처리한 다음 동일한 3차원 공간 내에서 정렬시켜 선택적 또는 동시적으로 3차원 영상을 가시화 하는 기법을 제안한다. 또한 3차원 영상에서 뇌정위 수술의 삽입점과 목표점을 지정할 수 있는 기능을 지원하며 수술 경로에 따른 가상 수술의 시뮬레이션을 통하여 수술 경로의 안전성을 검증할 수 있게 하였다.

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A case of primary central nervous system lymphoma diagnosed with cerebrospinal fluid analysis: replacement brain biopsy with cerebrospinal fluid immunohistochemistry and immunoglobulin gene rearrangement

  • Lee, Jun Ho;Yu, Shinae;Lee, Ja Young;Kim, Yeon Mee;Lee, Dong Ah;Kim, Sung Eun
    • Annals of Clinical Neurophysiology
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    • v.24 no.2
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    • pp.63-67
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    • 2022
  • Primary central nervous system lymphoma (PCNSL) is a type of non-Hodgkin lymphoma confined to the central nervous system. Its diagnosis requires a stereotactic biopsy, which is an invasive procedure. Cerebrospinal fluid (CSF) analysis is less invasive and easier to perform than a stereotactic biopsy. We hereby report a PCNSL case diagnosed using CSF analysis and treated with systemic chemotherapy.