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http://dx.doi.org/10.14253/acn.2022.24.2.63

A case of primary central nervous system lymphoma diagnosed with cerebrospinal fluid analysis: replacement brain biopsy with cerebrospinal fluid immunohistochemistry and immunoglobulin gene rearrangement  

Lee, Jun Ho (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine)
Yu, Shinae (Department of Laboratory Medicine, Haeundae Paik Hospital, Inje University of College of Medicine)
Lee, Ja Young (Department of Laboratory Medicine, Busan Paik Hospital, Inje University of College of Medicine)
Kim, Yeon Mee (Department of Pathology, Haeundae Paik Hospital, Inje University of College of Medicine)
Lee, Dong Ah (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine)
Kim, Sung Eun (Department of Neurology, Haeundae Paik Hospital, Inje University of College of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.24, no.2, 2022 , pp. 63-67 More about this Journal
Abstract
Primary central nervous system lymphoma (PCNSL) is a type of non-Hodgkin lymphoma confined to the central nervous system. Its diagnosis requires a stereotactic biopsy, which is an invasive procedure. Cerebrospinal fluid (CSF) analysis is less invasive and easier to perform than a stereotactic biopsy. We hereby report a PCNSL case diagnosed using CSF analysis and treated with systemic chemotherapy.
Keywords
Lymphoma; Central nervous system; Immunoglobulin gene;
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