• Archives of Pharmacal Research
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• v.25 no.4
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• pp.441-445
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• 2002

Three naphthalene glycosides (1-3), four flavonoids (4-7), and two galloyl glycosides (8-9) were isolated from the stem-bark of Juglans mandshurica (Juglandaceae). Their structures were determined by chemical and spectral means, including to 2D-NMR (COSY, HMQC, and HMBC) experiments. Amongst the isolated compounds, taxifolin (4) showed the most potent HIV-induced cytopethic activity against MT-4 cells with complete inhibitory concentration ($IC_{100}$) value of $25{\;}{\mu\textrm{g}}/ml$ and maximum cytotoxic concentration ($CC_{100}$) value of above $100{\;}{\mu\textrm{g}}/ml$. However, naphthalene glycosides (1-3), flavonoids (5-7)), and galloyl tannins (8-9) were inactive against anti-HIV-1 activity.

• 한국약용작물학회:학술대회논문집
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• 2009.05a
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• pp.319-320
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• 2009

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.371.2-371.2
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• 2002

Bioassay-directed chromatographic fractionation of a methylene chloride extract of Ailanthus altisshima indicated the presence of 20(S). 24(R), epoxy-25-hydroxydammarane-3-one(compound 1. ocotillone). which was isolated from this plant for the first time. Antimicrobial activity of compound 1 was measured by its degree of growth inhibition against bacterial and fungal cells and by a hemolytic assay with human erythrocytes, respectively. (omitted)

• Natural Product Sciences
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• v.4 no.4
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• pp.253-256
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• 1998

Chemical investigation of hot hexane extract of the stem bark of Gordonia ceylanica afforded a new triterpenoid, $3{\beta}-acetoxy-28-hydroxyolean-12-ene$ (1) and three other oleanane triterpenoids, $3{\beta}-hydroxyolean-12-ene$ (2), $3{\beta}-acetoxyolean-12-ene$ (3), and $3{\beta}-acetoxyolean-12-en-11-one$ (4) which are new to the species. Structure of compound 1 was suggested by $^1H\;NMR,\;^{13}C\;NMR$ and MS spectral data and confirmed by converting to previously reported compound, erythrodiol diacetate (5). Structures of 2, 3 and 4 were established by comparison of the spectral data with the previously reported compounds. Further the acid hydrolysate of 4 was identical with $3{\beta}-hydroxyolean-12-en-11-one$ (6).

• Journal of the Korean Wood Science and Technology
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• v.21 no.3
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• pp.45-52
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• 1993

Surveyed results on the slope of grain and the twist of sawn lumber of Pinus koraiensis, Larix leptolepis, and Pinus densiflora were summarized as follows: 1. The slope of grain of Pinus koraiensis has a Z-grain in the stem axis. The slope of grain was found to be the lowest at near to the pith and then constantly increased. At the height of 0.2m from the base of stem. a cross section of 35 annual rings was found to have a repeatedly increasing and decreasing slope of grain and then constantly decreased. At the height of 1.2m to 7.2m from the base of stem, the slope of grain increased conspicuously until the 10th annual ring, after which it increased near to the bark with repeatedly increasing and decreasing trends. 2. Pinus densiflora has a S-grain in the stem axis. The lowest slope of grain was found at near to the pith, and the highest in the 10 to 35 annual rings from the pith. 3. Larix leptolepis has a S-grain. At the height of 3.2m from the base of stem, the big fluctuation of the slope of grain was found without any particular trend. 4. The slope of grain and the twist between natural and reforested timber of Pinus koraiensis were found to be almost the same trend in viewpoint of the annual ring. The maximum slope of grain of imported Siberian timber of Pinus koraiensis was found at the 10 annual rings, which was quite similar to that of native species in Korea, but the big difference of the twist was found at 140 annual rings. 5. The twist was little at the mature wood of reforested Pinus koraiensis and Siberians and the duplicated part of mature and juvenile woods of those. On the contrary, the twist was great at the duplicated part of mature and juvenile woods of Pinus koraiensis. 6. The twist of Larix leptolepis showed the S-direction which coincided with that of slope of grain. The twist was greatest at the part of juvenile wood and little at the duplicated part of mature and juvenile woods, and little difference of twist was found between mature and juvenile woods. 7. Siberian larix having a minimum slope of grain showed the lowest twist, and the twist at the duplicated part of mature and juvenile woods showed a middle level of both mature and juvenile woods' portions.

• Journal of agriculture & life science
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• v.44 no.5
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• pp.45-53
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• 2010

This study was conducted to examine the biomass and net primary production, stem density and biomass expansion factors of Pinus densiflora in Gochang regions. The mean age of Pinus densiflora in both stands was 10 and 48 years. The dry weights (kg/tree) and aboveground biomass (Mg/ha) were 8.59 and 17.55 for 10 years young stand, 166.66 and 122.05 for 48 years old stand. The total biomass (Mg/ha) including the above and belowground were 21.48 and 154.16 in both age stands. The proportion of stem biomass, stem bark biomass and root biomass increased from the young stand to the old stand while on the leaf biomass and branch biomass, tend to decreased. The net primary production of aboveground biomass (Mg/ha) and belowground biomass were 6.30~6.95 for the young stand and 11.61~13.19 for old stand. The stem density ($g/cm^3$) was 0.338 for young stand while on the other hand, 0.448 for old stand was observed. The above and total biomass expansion factors were 2.304~2.508 and 1.318~1.644 in each age stands, respectively.

• Journal of Microbiology and Biotechnology
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• v.17 no.1
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• pp.21-28
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• 2007

The crude biopolymer (AS-S1) and endobiopolymer (AS-S2) were isolated from the dry stem bark of Acanthopanax sessiliflorus and tested for anti complement activity. The two potent anticomplement biopolymers, AS-1 and AS-2-Fr.I, were isolated by the combination of ion-exchange chromatography and gel filtration methods from the endo-biopolymers (AS-S2). The anticomplement activity of AS-1 (MW 12 kDa) and AS-2-Fr.I (MW 180 kDa) were found to be 84.4% and 100.0%, respectively, at the concentration of $25{\mu}g/ml$. Activated pathway of the complement system occurred in both classical and alternative pathways, as evidenced by crossed immunoelectrophoresis(CIEP), where a major pathway was detected to be the classical one. It was found that the anticomplement activities of the periodate oxidized were decreased significantly, but those of pronase digested biopolymers of AS-1 and AS-2-Fr.I were decreased very little. The AS-1 contained 2,4,6-tri-O-methyl-D-glucitol, 2,3,6-tri-O-methyl-D-galacitol, and 2,3,6-tri-O-methyl-D-galacitol, which indicated that AS-1 contained a $(1{\rightarrow}3),\;(1{\rightarrow}4)-linked$ glucopyranosyl residue and a $(1{\rightarrow}4)-linked$ galactosyl residue. AS-2-Fr.I contained mainly 2,4-di-O-methyl-D-mannitol and 2,3,4-tri-O-methyl-D-galacitol, which contained $(1{\rightarrow}3),\;(1{\rightarrow}6)$ linked mannosyl and $(1{\rightarrow}6)$ linked galactosyl residues.

• Journal of Pharmacopuncture
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• v.20 no.1
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• pp.45-51
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• 2017

Objectives: This study aimed to evaluate the hypoglycemic effects of an ethanol extract of Cassia abbreviata (ECA) bark and the possible mechanisms of its action in diabetic albino rats. Methods: ECA was prepared by soaking the powdered plant material in 70% ethanol. It was filtered and made solvent-free by evaporation on a rotary evaporator. Type 2 diabetes was induced in albino rats by injecting 35 mg/kg body weight (bw) of streptozotocin after having fed the rats a high-fat diet for 2 weeks. Diabetic rats were divided into ECA-150, ECA-300 and Metformin (MET)-180 groups, where the numbers are the doses in mg.kg.bw administered to the groups. Normal (NC) and diabetic (DC) controls were given distilled water. The animals had their fasting blood glucose levels and body weights determined every 7 days for 21 days. Oral glucose tolerance tests (OGTTs) were carried out in all animals at the beginning and the end of the experiment. Liver and kidney samples were harvested for glucose 6 phosphatase (G6Pase) and hexokinase activity analyses. Small intestines and diaphragms from normal rats were used for ${\alpha}-glucosidase$ and glucose uptake studies against the extract. Results: Two doses, 150 and 300 mg/kg bw, significantly reduced the fasting blood glucose levels in diabetic rats and helped them maintain normal body weights. The glucose level in DC rats significantly increased while their body weights decreased. The 150 mg/kg bw dose significantly increased hexokinase and decreased G6Pase activities in the liver and the kidneys. ECA inhibited ${\alpha}-glucosidase$ activity and promoted glucose uptake in the rats' hemi-diaphragms. Conclusion: This study revealed that ECA normalized blood glucose levels and body weights in type 2 diabetic rats. The normalization of the glucose levels may possibly be due to inhibition of ${\alpha}-glucosidase$, decreased G6Pase activity, increased hexokinase activity and improved glucose uptake by muscle tissues.

• Korean Journal of Plant Resources
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• v.17 no.3
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• pp.314-322
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• 2004

This research has been undertaken to increase availiability of native Camellia japonica leaf and flower in Korea as a edible-medicinal resource. Chemical compositions, antioxidant and antimicrobial activities in different parts of camellia were investigated. Crude protein contained the highest in young leaves(14.22%) but less than 10% in different parts. The contents of crude fat and crude ash were 60.48% in seeds and 5.16% in mature leaves, respectively. Methanol extract of young leaf, flower, and flower bud in camellia showed strong antioxidant activity compared with different parts. Also, antioxidant activity of these was higher than that of BHT, but weaker than that of VtC. Antioxidant activity of various parts in camellia were in order of young leaf ＆gt; flower bud ＆gt; flower ＆gt; mature leaf ＆gt; stem ＆gt; bark. Extracts of mature leaf and bark had a remarkable antibacterial activity(0 CFU/$m\ell$) on Bacillus subtilis. The young leaf extract displayed effective growth inhibition against B. subtilis, Candida albicans, and Trichosporon beigelii.

• The Korea Journal of Herbology
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• v.38 no.5
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• pp.21-29
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• 2023

Objects : This study aimed to identify the origin species of Ulmi Cortex and Ulmi Semen Pasta. Methods : I searched for different types of 'Yu(楡)' from Zhong Xiu Zheng Huo Jing Shi Zheng Lei Bei Yong Ben Cao (重修政和經史證類備用本草) of the Song Dynasty, then compared the descriptions of Yu with real life species. Items that were inconsistent were sequentially deleted to finally find the original species that satisfies all conditions. Results : There were five types of Yu : Jiyu(地楡), Jayu(刺楡), Langyu(郞楡), Goyu(姑楡), and Baekyu(白楡). Jiyu was Sanguisorba officinalis or Sanguisorba officinalis var. longifolia which was a herb. Jayu was Hemiptelea davidii (Hance) Planch. which had thorns on its branches. Ulmus laciniata had leaves that split into three branches. Langyu was Ulmus parvifolia which beared fruit in the fall. For these reasons, the four items above were ruled out. The fruit of Goyu was Ulmi Semen Pasta, which was the largest among fruits and was therefore Ulmus macrocarpa. The fruit of Baekyu was Yuhyup(楡莢) and the ancient coin Yuhyupjeon(楡莢錢) was resembled Yuhyup. The normal pulse of the lung resembled the appearance of falling Yuhyup. The peel of Baekyu was Yubaekpi(楡白皮), and when it was removed from coarse bark, contained an abundance of white sap; the place where this sap overflowed on the stem bark was white, therefore Baekyu was identified as Ulmus pumila. Conclusions : From the results above, the origin species of Ulmi cortex was Ulmus pumila and the origin species of Ulmi Semen Pasta was Ulmus macrocarpa.