• Genomics & Informatics
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• v.17 no.4
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• pp.47.1-47.12
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• 2019

The achievements of genome-wide association studies have suggested ways to predict diseases, such as type 2 diabetes (T2D), using single-nucleotide polymorphisms (SNPs). Most T2D risk prediction models have used SNPs in combination with demographic variables. However, it is difficult to evaluate the pure additive contribution of genetic variants to classically used demographic models. Since prediction models include some heritable traits, such as body mass index, the contribution of SNPs using unmatched case-control samples may be underestimated. In this article, we propose a method that uses propensity score matching to avoid underestimation by matching case and control samples, thereby determining the pure additive contribution of SNPs. To illustrate the proposed propensity score matching method, we used SNP data from the Korea Association Resources project and reported SNPs from the genome-wide association study catalog. We selected various SNP sets via stepwise logistic regression (SLR), least absolute shrinkage and selection operator (LASSO), and the elastic-net (EN) algorithm. Using these SNP sets, we made predictions using SLR, LASSO, and EN as logistic regression modeling techniques. The accuracy of the predictions was compared in terms of area under the receiver operating characteristic curve (AUC). The contribution of SNPs to T2D was evaluated by the difference in the AUC between models using only demographic variables and models that included the SNPs. The largest difference among our models showed that the AUC of the model using genetic variants with demographic variables could be 0.107 higher than that of the corresponding model using only demographic variables.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.4
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• pp.54-64
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• 1999

This paper proposes an efficient handwritten English word recognition scheme which can be applied practical applications. To effectively use the lexicon which is available in most handwriting related applications, the lexicon entries are introduced in the early stage of the recognition. Dynamic programming is used for matching between over-segmented character segments and letters in the lexicon entries. Character segmentation statistics which can be obtained while the training is being performed are used to adjust the matching window size. Also, the matching results between the character segments and the letters in the lexicon entries are cached to avoid repeat of the same computation. In order to verify the effectiveness of the proposed methods, several experiments were performed using thousands of word images with various writing styles. The results show that the proposed methods significantly improve the matching speed as well as the accuracy.

• Proceedings of the Korean Society for Language and Information Conference
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• 1995.02a
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• pp.121-126
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• 1995

A new method for Chinese word segmentation named Conditional F'||'&'||'BMM (Forward and Backward Maximal Matching) which incorporates both bigram statistics (ie., mutual infonllation and difference of t-test between Chinese characters) and linguistic rules for ambiguity resolution is proposed in this paper The key characteristics of this model are the use of: (i) statistics which can be automatically derived from any raw corpus, (ii) a rule base for disambiguation with consistency and controlled size to be built up in a systematic way.

• 한국데이터정보과학회:학술대회논문집
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• 2004.04a
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• pp.15-23
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• 2004

When X and Y have independent two parameter exponential distributions, we develop a Bayesian testing procedures for the equality of two location parameters. Under the noninformative prior, we propose a Bayesian test procedures for the equality of two location parameters using fractional Bayes factor and intrinsic Bayes factor. Simulation study and some real data examples are provided.

• Journal of the Korean Statistical Society
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• v.31 no.1
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• pp.17-31
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• 2002

This paper considers noninformative priors for the power law process under failure truncation. Jeffreys'priors as well as reference priors are found when one or both parameters are of interest. These priors are compared in the light of how accurately the coverage probabilities of Bayesian credible intervals match the corresponding frequentist coverage probabilities. It is found that the reference priors have a definite edge over Jeffreys'prior in this respect.

• Journal of the Korean Data and Information Science Society
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• v.24 no.3
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• pp.643-650
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• 2013

We develop noninformative priors for a ratio of parameters of two Maxwell distributions which is used to check the equality of two Maxwell distributions. Specially, we focus on developing probability matching priors and Je reys' prior for objectiv Bayesian inferences. The probability matching priors, under which the probability of the Bayesian credible interval matches the frequentist probability asymptotically, are developed. The posterior propriety under the developed priors will be shown. Some simulations are performed for identifying the usefulness of proposed priors in objective Bayesian inference.

• Journal of the Korean Data and Information Science Society
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• v.27 no.4
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• pp.1091-1100
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• 2016

This paper considers the noninformative priors for the linear function of parameters in the lognormal distribution. The lognormal distribution is applied in the various areas, such as occupational health research, environmental science, monetary units, etc. The linear function of parameters in the lognormal distribution includes the expectation, median and mode of the lognormal distribution. Thus we derive the probability matching priors and the reference priors for the linear function of parameters. Then we reveal that the derived reference priors do not satisfy a first order matching criterion. Under the general priors including the derived noninformative priors, we check the proper condition of the posterior distribution. Some numerical study under the developed priors is performed and real examples are illustrated.

• Proceedings of the Korean Association for Survey Research Conference
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• 2006.12a
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• pp.67-83
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• 2006

In successive sampling on two occasions the problem of estimating a finite population quantile has been considered. The theory developed aims at providing the optimum estimates by combining (i) three double sampling estimators viz. ratio-type, product-type and regression-type, from the matched portion of the sample and (ii) a simple quantile based on a random sample from the unmatched portion of the sample on the second occasion. The approximate variance formulae of the suggested estimators have been obtained. Optimal matching fraction is discussed. A simulation study is carried out in order to compare the three estimators and direct estimator. It is found that the performance of the regression-type estimator is the best among all the estimators discussed here.

• Journal of the Korean Statistical Society
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• v.36 no.4
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• pp.543-556
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• 2007

In successive sampling on two occasions the problem of estimating a finite population quantile has been considered. The theory developed aims at providing the optimum estimates by combining (i) three double sampling estimators viz. ratio-type, product-type and regression-type, from the matched portion of the sample and (ii) a simple quantile based on a random sample from the unmatched portion of the sample on the second occasion. The approximate variance formulae of the suggested estimators have been obtained. Optimal matching fraction is discussed. A simulation study is carried out in order to compare the three estimators and direct estimator. It is found that the performance of the regression-type estimator is the best among all the estimators discussed here.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.05a
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• pp.894-897
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• 2008

The stress is an unavoidable result and a complex phenomenon in modem society. too, Human activity changes under control of the stress. The stress is a reaction to adrenalin or other stress hormones. It provides the power for fighting and the energy for going away from dangers. Because of the stress, our bodies increase the pulse, the blood pressure and the breath for more blood and more oxygen. So, in this research, we are measuring those which was increased by the stress. Also we will examine the change of HRV and APG on music. After that, in order to reduce the stress, we will design matching system that is based on the sense for music by using Zigbee.