• Journal of Korean Academy of Nursing
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• v.20 no.3
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• pp.399-413
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• 1990

This descriptive study was under taken to explore relationships among the quality of life, health locus of control and perceived state of health persons with cancer to contribute theoretical understanding about these phenomenon of interest to the quality of nursing care. The subjects of this were 200 persons with cancer (100- in patients and 100- out patients), both male and female, between 30 and 59 years of age. Data were obtained using a convenience sample technique from two university hospitals in seoul from August, 1989, to June, 1990. The instruments used for this study were the Quality of life scale developed by Ro, You - Ja and the Health Locus of Control scale developed by Wallston & Wallston. Data were analyzed using a SAS program for ANOVA, t-test, Schefffe test, Pearson Correlation Coefficients and Stepwise multiple regression. The results were as follows : 1. The scores on the quality of life scale ranged from 95 to 191 with as mean of 147.85(range 47 to 235). The Mean scores(range 1-5) on the different dimensions were family relationships 3.50, relationships with neighbours 3.48, self - esteem 3.17, physical state and function 2.99, economic life 2.93 and emotional life 2.91. 2. Significantly higher scores on the quality of life and demographic characteristics were as follows : the quality of life for women(t＝2.80, p＝ .006), for those without complications(t＝2.54, p＝ .013), and for those who perceived their illness as mild(F＝4.85, p＝ .009). Higher scores on quality of life were correlated with the following : 1) emotional state and the age group 50-59(F＝3.43, p＝ .34). 2) economic life and higher income(F＝6.72, p＝ .002), those without complications(t＝2.68, p＝ .00), and those who perceived their illness as mild(F＝3.11, p＝ .05). 3) self-esteem and marriage(F＝3.64, p＝.028), those without complications(t＝2.18, p＝.03), and those who perceived their illness as mild(F＝7.72, p＝.000). 4) physical state and funciton and the age group 30-39(F＝4.65, p＝.010), those without complications (t＝2.00, p＝.05), and those who perceived their illness as mild(F＝3.38, p＝.04). 5) family relationship and those who live with their spouse(t＝2.82, p＝.005). 3. There was a significant positive correlation between the subjects perceptions of their current state of health and the quality of life score(r＝.4364, p＝.0001). 4. There was no relationship between Locus of control and quality of life in this sample. 5. Stepwise multiple regression analysis showed that: 1) the perception of current health status was the main predictor and accounted for 20.11% of the total variance. 2) sex and educational level accounted for an additional 21.71% of the total variance. 6. The quality of life and the perception of their current health status of these patients with cancer were generally lower than those of healthy adults as noted in previous studies. In conclusion, the quality of life for these cancer patients was generally low especially in regard to their emotional state. The current perceived state of health, sex, complications and perceived degree of illness were important variables relatiog to quality of life.

• Korean Journal of Health Education and Promotion
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• v.23 no.4
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• pp.125-153
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• 2006

This study was intended to describe women's weight controlling by creating a hypothetic model on the weight adjustment behavior and by examining a cause and effect relationship, and to contribute to countermeasures for practicing their promotion of health and improving the quality of life through creating a predictable model. The subject of study was women who utilize the beauty shop located in Seoul, Busan and Daegu and the study period was 12 weeks from July 10 to September 30 in 2004. Gathered 1093 person's general specialty related with weight adjustment and analyzed covariance to prove the hypothesis using statistics compiled from authentic sources. Also proved coincidence of the hypothetical model. Exogenous variables of the hypothetical model are composed of recognition of her body shape, fatness level, age, stress, and self-respect. Endogenous variables are health- control mind, recognized health state, self-efficacy, intention, and behavior of weight adjustment. There were 5 measured variables for exogenous variable(x). There were 8 measured variable(y) for exogenous variable. And coincidence $x^2=297.38$, standard $x^2(x^2/df)=7.08$, GFI=0.962, AGFI=0.917, NFI=0.875, TLI=0.794, CFI=0.889, RMSEA=0.075. The result of hypothesis had an epoch-making record that 20 out of 27 hypothesis was proved positive way. Generally weight adjustment has been highly seen in housewives, the married and the old age. Health control mind seems to be high as fatness level, age, and self-respect are high and low stress. Recognized health state is high as age and self-respect are high and low stress. However, it is not much related with recognition of her body shape and fatness level. If age, self-respect, health control mind, recognized health state and self-efficacy are high intention of behavior is also high, but intention of behavior has no relation with recognition of her body shape, fatness level and stress. If fatness level, age, self-respect, health control mind, recognized health state and self-efficacy and intention of behavior are high, execution of weight adjustment will be high. However, recognized health state and stress has no influence for weight adjustment. To increase the coincidence of hypothesis and take a simple model I modified a model and then I got the coincidence $x^2=215.62$, standard $x^2(x^2/df)=6.34$, GFI=0.970, AGFI=0.931, NFI=0.902, TLI=0.901, CFI=0.915, RMSEA=0.070. This result is a bit better than original hypothetical model's so that this model might be more suitable. In this modification model, the factors of weight adjustment seems to be high according to this order self-efficacy, recognized health state, age, intention, health control mind, self-respect, fatness level and stress. With this result I suggest ; 1. Enforcement of IR that everybody can be controlled weight adjustment herself and continuous education, which is related with regular habit (food, exercise, restriction of a favorite food and behavior training etc.) is also needed. 2. Because self-efficacy is influenced to execution of weight adjustment specific program which can increase self-efficacy should have to develop and we need to utilize it to take care of herself. 3. To protect fatness and be active weight adjustment the peculiar program including the concept of self-respect, recognized health state, health control mind and intention must be developed and not only women but also all of people should be educated. 4. This hypothetical model is forecasting women's weight adjustment behavior and can be utilized for fundamental data to increase those people's health.

• Experimental and Molecular Medicine
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• v.50 no.12
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• pp.3.1-3.14
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• 2018

Type 1 diabetes mellitus (T1DM) is a pathological condition associated with osteopenia. $WNT/{\beta}$-catenin signaling is implicated in this process. Trabecular and cortical bone respond differently to $WNT/{\beta}$-catenin signaling in healthy mice. We investigated whether this signaling has different effects on trabecular and cortical bone in T1DM. We first established a streptozotocin-induced T1DM mouse model and then constitutively activated ${\beta}$-catenin in osteoblasts in the setting of T1DM (T1-CA). The extent of bone loss was greater in trabecular bone than that in cortical bone in T1DM mice, and this difference was consistent with the reduction in the expression of ${\beta}$-catenin signaling in the two bone compartments. Further experiments demonstrated that in T1DM mice, trabecular bone showed lower levels of insulin-like growth factor-1 receptor (IGF-1R) than the levels in cortical bone, leading to lower $WNT/{\beta}$-catenin signaling activity through the inhibition of the IGF-1R/Akt/glycogen synthase kinase $3{\beta}$ ($GSK3{\beta}$) pathway. After ${\beta}$-catenin was activated in T1-CA mice, the bone mass and bone strength increased to substantially greater extents in trabecular bone than those in cortical bone. In addition, the cortical bone of the T1-CA mice displayed an unexpected increase in bone porosity, with increased bone resorption. The downregulated expression of WNT16 might be responsible for these cortical bone changes. In conclusion, we found that although the activation of $WNT/{\beta}$-catenin signaling increased the trabecular bone mass and bone strength in T1DM mice, it also increased the cortical bone porosity, impairing the bone strength. These findings should be considered in the future treatment of T1DM-related osteopenia.

• Journal of Ginseng Research
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• v.47 no.6
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• pp.694-705
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• 2023

Panax ginseng Meyer is a traditional Chinese medicine that is widely used as tonic in Asia. The main pharmacologically active components of ginseng are the dammarane-type ginsenosides, which have been shown to have anti-cancer, anti-inflammatory, immunoregulatory, neuroprotective, and metabolic regulatory activities. Moreover, some of ginsenosides (eg, Rh2 and Rg3) have been developed into nutraceuticals. However, the utilization of ginsenosides in clinic is restrictive due to poor permeability in cells and low bioavailability in human body. Obviously, the dammarane skeleton and glycosyls of ginsenosides are responsible for these limitations. Therefore, improving the oral bioavailability of ginsenosides has become a pressing issue. Here, based on the structures of ginsenosides, we summarized the understanding of the factors affecting the oral bioavailability of ginsenosides, introduced the methods to enhance the oral bioavailability and proposed the future perspectives on improving the oral bioavailability of ginsenosides.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.881-882
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• 2006

According as society looks graying trend gradually, more shaped system that can achieve measuring health-state of old people more harmoniously construction required in field of old people's welfare and medical treatment. Health-state is measured by two methods of contact and non-contact. The first, for example measurement of blood pressure or electrocardiogram, requires that measuring equipments are attached on human body but the second, for example X-Ray or MRI, is not. But both of methods are have some of defect, for example attaching equipments, needing of the special equipments or the necessary time, etc. Therefore desirable method of monitoring system must have minimum interrupt about daily life. This study suggest the system that can monitor the user, especially old people's outward aging and health-state by use the PAN TILTER and CCD camera.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1254-1262
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• 1999

The purpose of this study was to examine the effects of 6-wk low intensity exercise program on fatigue, perceived health state, exercise-related affect, perceived benefits, and exercise self-efficacy for female college student's. The subjects of the study consisted of thirty-four female college students. The research subjects were assigned to experimental and control group. The experimental group participated in 13-17 and 30-60 minute sesseions of exercise program over 6 weeks. Data analysis was done by t-test with SAS program. The results of this study are as follows. 1) The first hypothesis, “The fatigue of experimental group will be lower than control group”, was supported. 2) The second hypothesis, “The perceived health state of experimental group will be higher than control group”, was not supported. 3) The third hypothesis, “The exercise-related affect of experimental group will be higher than control group”, was not supported. 4) The fourth hypothesis, “The benefits of exercise of experimental group will be higher than control group”, was not supported. 5) The fifth hypothesis, “The self-efficacy for exercise of experimental group will be higher than control group”, was supported.

• Journal of Korean Academy of Nursing
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• v.40 no.1
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• pp.119-126
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• 2010

Purpose: The study was done to identify factors influencing the sleep of elderly women. Methods: Data were collected by questionnaires from 203 elderly women in Seoul and Gyeong-gi province. Measures were physical health state, family support, life satisfaction, sleep, depression, and quality of life. Data were analyzed using Pearson correlation coefficients, t-test, ANOVA, and stepwise multiple regression with SPSS/WIN 13.0 version. Results: The mean score for sleep for elderly women was 39.04. Sleep for elderly women according to religion, education level, spouses, and monthly income showed significant differences. Sleep for elderly women showed significantly positive correlations to physical health state, family support, life satisfaction, and quality of life. The significant factors influencing sleep of elderly women were physical health state, family support, depression, and quality of life, which explained about 70.4% of the variance. The strongest factors influencing the sleep was physical health state. Conclusion: The results suggest that in developing nursing interventions and practice for sleep pattern of elderly women spouses and family support should be considered.

• Journal of Korean Academy of Nursing
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• v.32 no.5
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• pp.654-664
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• 2002

The purpose of this study was to identify the burden, health promotion behavior and health status and to describe the relationship of the burden, health promotion behavior and health status of the family caregivers of intensive care unit patients. Method: The subjects were 48 family caregivers of ICU patients in a University Hospital. Data were collected between June, 1 and July, 31, 2000 using structured questionnaires. Research tools used were Suh and Oh's Burden Scale, Revised Walker, Sechrist, & Pender's HPLP(1987) ; Revised Nam's Health State Scale(1965). Result: The mean score of burden of family caregiver was 3.01(full score was 5). The mean score of health promotion behavior of family caregiver was 2.52(full score was 4). And the mean score of health status of family caregiver was 0.68(full score was 1.00). The score of psychological health state was a little higher than the physiological one. In correlational analysis, the burden and the health status of caregivers were reversely correlated . The correlation between the burden and the health promotion behavior, and the health behavior and health status were not significant. Conclusion: The more burden caregivers of ICU patients felt, the worse their health status. So nurses need to understand the family caregiver's burden and apply nursing care that can reduce burden, in order to improve the health status of family caregivers.

• Journal of Sasang Constitution and Immune Medicine
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• v.20 no.2
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• pp.11-20
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• 2008

1. Objectives The objective of this paper is to understand on treatment of in critical state patients based on the text book of Sasang Constitutional Medicine. We expect this study can be helpful in treating the critical state patients. 2. Methods The study is mainly based on the bibliographical research on the "Dongyisoosebowon" and on the "Principle of dosing for patient in critical state". 3. Results and conclusions Lee je-ma suggested a health scale which people can measure his health grade from a standard healthy state to severe diseases. We investigated the treatment of 'critical state' patients according to his scale. Lee je-ma also confirmed the standard dose of herbs and how to take herbs in compliance with the state which each patient in. We tried to find a rules of treating the critical state patients based on the text "Dongyisoosebowon" and we suggested brief principles in treating patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2609-2619
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• 2015

The purpose of this study was to investigate relationship among the depression, physical condition, daily living activities, and sleep state among old people at elderly care facilities. The subjects include old people aged 65 or older residing at an elderly care facility. At elderly care facilities, the depression of old people was related with the state of vision, mastication ability, quality of sleep, and sleep state. The degree of relation was high in the group with a poor vision, the one with a bad condition of teeth, the one that considered their quality of sleep to be poor, and the one with somnipathy. Their depression had negative correlations with age and positive ones with mastication ability and assessment of quality of sleep. At elderly care facilities, the depression of old people was highly connected with the state of vision, mastication ability, sleep state, and hearing ability. In short, the depression of old people at elderly care facilities is highly connected to the health state perceived individually. The findings point to the importance of close interest in individual health state and management of old people in poor vision, mastication ability in healthcare and nursing intervention.