• Title/Summary/Keyword: Start-up Condition

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Development and validation of a difficulty index for mandibular third molars with extraction time

  • Ku, Jeong-Kui;Chang, Na-Hee;Jeong, Yeong-Kon;Baik, Sung Hyun;Choi, Sun-Kyu
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.46 no.5
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    • pp.328-334
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    • 2020
  • Objectives: This study aimed to validate the effectiveness of a recently proposed difficulty index for removal of impacted mandibular third molars based on extraction time and suggest a modified difficulty index including the presence of pathologic conditions associated with third molars. Materials and Methods: This retrospective study enrolled 65 male patients younger than 25 years with third molars. Extraction time was calculated from start of the incision to the last suture. The difficulty scores for third molars were based on spatial relationship (1-5 points), depth (1-4 points), and ramus relationship (1-3 points) using cone-beam computed tomography. The difficulty index was defined as follows: I (3-4 points), II (5-7 points), III (8-10 points), and IV (11-12 points). The modified difficulty score was calculated by adding one point to the difficulty score if the third molar was associated with a pathologic condition. Two modified difficulty indices, based on the presence of pathologic conditions, were as follows: the half-level up difficulty index (HDI) and the one-level up difficulty index (ODI) from the recently proposed difficulty index. Results: The correlations between extraction time and difficulty index and or modified difficulty indices were significant (P<0.001). The correlation coefficient between extraction time and difficulty index was 0.584. The correlation coefficients between extraction time and HDI and ODI were 0.728 and 0.764, respectively. Conclusion: Extraction time of impacted third molars exhibited a moderate correlation with difficulty index and was strongly correlated with the modified indices. Considering the clinical implications, the difficulty index of surgical extraction should take into consideration the pathologic conditions associated with third molars.

An Empirical Study on the Determinants of Re-startup Firm's Performance by the Condition of Credit Problems (신용문제에 따른 재창업기업 성과 결정 요인에 대한 실증연구)

  • Kim, In Sue;Lee, Taek Ku
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.13 no.2
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    • pp.15-26
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    • 2018
  • This study examines the effects of failure experience, re-startup's motivation, government support business and education for re-startup on the performance of re-startup firms after failure. In addition, we analyzed how the above factors affect the performance of re-startup firms by the condition of debt and credit problems. As a result of the analysis, the failure experience had no significant effect on the re-startup performance regardless of the credit problem, while re-startup's motivation, government support business and education for re-startup had a significant effect on re-startup firms' performance. In the re-startup group with the credit problem, the re-startup's motivation and the failure experience had a significant influence on the re-startup firms' performance. On the other hand, in the group that did not solve the credit problem, the re-startup's motivation and the failure experience had no significant effect on the re-startup performance, but the government support business and education for re-startup had a significant effect on re-startup performance. The results of this study are as follows: First, it shows that the characteristics of re-startups and the determinants of re-startups are different according to credit problems. Second, this study shows that it takes 56 months on average from the close of business to the re-start, and it may take more than 7 years due to the credit problems and bankruptcy. This suggests the necessity to consider re-startup in the concept of obsolete in consideration of time, when studying the direct/indirect influence of failure experience and re-startup, and establishing policy.

Identification of Genes Modulated by High Extracellular Calcium in Coculture of Mouse Osteoblasts and Bone Marrow Cells by Oligo Chip Assay

  • Kim, Hyung-Keun;Song, Mi-Na;Jun, Ji-Hae;Woo, Kyung-Mi;Kim, Gwan-Shik;Baek, Jeong-Hwa
    • International Journal of Oral Biology
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    • v.31 no.2
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    • pp.53-65
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    • 2006
  • Calcium concentration in the bone resorption lacunae is high and is in the mM concentration range. Both osteoblast and osteoclast have calcium sensing receptor in the cell surface, suggesting the regulatory role of high extracellular calcium in bone metabolism. In vitro, high extracellular calcium stimulated osteoclastogenesis in coculture of mouse osteoblasts and bone marrow cells. Therefore we examined the genes that were commonly regulated by both high extracellular calcium and $1,25(OH)_2vitaminD_3(VD3)$ by using mouse oligo 11 K gene chip. In the presence of 10 mM $[Ca^{2+}]e$ or 10 nM VD3, mouse calvarial osteoblasts and bone marrow cells were co-cultured for 4 days when tartrate resistant acid phosphatase-positive multinucleated cells start to appear. Of 11,000 genes examined, the genes commonly regulated both by high extracellular calcium and by VD3 were as follows; 1) the expression of genes which were osteoclast differentiation markers or were associated with osteoclastogenesis were up-regulated both by high extracellular calcium and by VD3; trap, mmp9, car2, ctsk, ckb, atp6b2, tm7sf4, rab7, 2) several chemokine and chemokine receptor genes such as sdf1, scya2, scyb5, scya6, scya8, scya9, and ccr1 were up-regulated both by high extracellular calcium and by VD3, 3) the genes such as mmp1b, mmp3 and c3 which possibly stimulate bone resorption by osteoclast, were commonly up-regulated, 4) the gene such as c1q and msr2 which were related with macrophage function, were commonly down-regulated, 5) the genes which possibly stimulate osteoblast differentiation and/or mineralization of extracellular matrix, were commonly down-regulated; slc8a1, admr, plod2, lox, fosb, 6) the genes which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were commonly up-regulated; s100a4, npr3, mme, 7) the genes such as calponin 1 and tgfbi which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were up-regulated by high extracellular calcium but were down-regulated by VD3. These results suggest that in coculture condition, both high extracellular calcium and VD3 commonly induce osteoclastogenesis but suppress osteoblast differentiation/mineralization by regulating the expression of related genes.

A Study on the Utilization of Empty Houses in Rural Village - Focused on the Hacheon Village in Gimje City - (농촌마을 빈집의 활용방안에 관한 연구 - 김제 하천마을 중심으로 -)

  • Shim, Yu-Hyeon;Shin, Byeong-Uk;Nam, Hae-Kyeong
    • Journal of the Korean Institute of Rural Architecture
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    • v.24 no.1
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    • pp.27-36
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    • 2022
  • Currently the population of rural areas in Korea continue to decline due to low birth rate, aging population, and migration. This phenomenon is accelerated over time. And as a result, there are some declining phenomenon in rural society. And it is same in the residential and basic living conditions of rural villages. The increase ratio of empty houses exacerbates the rural landscape, acts as a cause of crime and bring out various social and economic problems such as worsening settlement conditions and local slums. The study is carried out to prevent this phenomenon by investigating the architectural contents of empty houses in the village, surveyed residents and owners and finally analyzed and synthesized to make a plan to utilize empty houses in the village. This study was conducted from June to December 2021. The conclusions are followings: 1. The empty houses in Korea were 1,511 million in 2020, 8.2% of the total number of houses, whereas those in Jeollabuk-do were 95,412, 12.9% of those of houses, and those in Gimje-city, the subject of this study, were 5,944. It is up to 15.8%. In particular, empty houses in Hacheon village, the site of this study, accounted for the highest ratio, with 25% of the total number of houses. 2. To understand the utilization and improvement of empty houses, surveys and interviews were conducted to residents and owners of Hacheon village in Gimje, and most of the residents submit proposals that empty houses were not desirable in terms of village landscape and safety. The owners don't have intentions of selling or leasing them. They want to remodel them and rent for a specific period. 3. As the physical condition of the empty houses(9empty houses) 6 empty houses of them are good. 4 of them are in poor condition. 4. By synthesizing these contents, nine empty houses in Hacheon village will be remodeled as the space for those of rural start-up young people, smart farm area, community space and rental housings for rural returnees.

A Study on the Effect of User Value on Smartwatch Digital HealthcareAcceptance Intention to Promote Digital Healthcare Venture Start Up (Digital Healthcare 벤처창업 촉진을 위한, 사용자 가치가 Smartwatch Digital Healthcare 수용의도에 미치는 영향 연구)

  • Eekseong Jin;soyoung Lee
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.2
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    • pp.35-52
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    • 2023
  • Recently, as the non-face-to-face environment has developed due to COVID-19 and environmental pollution, the importance of online digital healthcare is increasing, and venture start-ups and activities such as health care, telemedicine, and digital treatments are also actively underway. This study conducted the impact on the acceptability of digital healthcare smartwatches with an integrated approach of the expanded integrated technology acceptance model (UTAUT2) and the behavioral inference model (BRT). The most advanced integrated technology acceptance model for innovative technology acceptance research was used to identify major factors such as utility expectations, social effects, convenience, price barriers, lack of alternatives, and behavioral intentions. For the study, about 410 responses from ordinary people in their teens to 60s across the country were collected, and based on this, the hypothesis was verified using structural equations after testing reliability and validity of the data. SPSS 23 and AMOS 23 were used for research analysis. Studies have shown that personal innovation has a significant impact on the reasons for acceptance (use value, social impact, convenience of use), attitude, and non-use (price barriers, lack of alternatives, and barriers to use). These results are the same as the results of previous studies that confirmed the influence of the main value of innovative ICT on user acceptance intention. In addition, the reason for acceptance had a significant effect on attitude, but the effect of the reason for non-acceptance was not significant. It can be analyzed that consumers are interested in new ICT products and new services, but purchase them more carefully and selectively. This study has evolved from the acceptance analysis of general-purpose consumer innovation technology to the acceptance analysis of consumer value in smartwatch digital healthcare, which is a new and important area in the future. Industrially, it can contribute to the product's purchase and marketing. It is hoped that this study will contribute to increasing research in the digital healthcare sector, which will play an important role in our lives in the future, and that it will develop into in-depth factors that are more suitable for consumer value through integrated approach models and integrated analysis of consumer acceptance and non-acceptance.

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A Mixed Approach for Single-Vendor-Single-Buyer Production Inventory Integration Problem (판매자-구매자 생산-재고통합 문제를 위한 Mixed Approach)

  • Lee, Dongju
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.4
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    • pp.7-14
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    • 2016
  • Unlike most researches that focus on single manufacturer or single buyer, this research studies the cooperation policy for two participants of supply chain such as single vendor and single buyer. Especially, this paper deals with single vendor-single buyer integrated-production inventory problem. If the buyer orders products, then the vendor will start to make products and then the products will be shipped from the vendor to the buyer many times. The buyer is supposed to order again when the buyer's inventory level hits reorder point during the last shipment and this cycle keeps repeated. The buyer uses continuous review inventory policy and customer's demand is assumed to be probabilistic. The contribution of this paper is to present a mixed approach and derive its cost function. The existing policy assumes that the size of shipping batch from single vendor to single buyer is increasing, called Type 1, or constant, called Type 2. In mixed approach, the size of shipping batch is increasing at the beginning part of the cycle, and then its size is constant at the ending part of the cycle. The number of shipping for Type 1 and Type 2 in a cycle in mixed approach is determined to minimize total cost. The relationship between parameters, for example, the holding cost per product, the set up cost per order, and the shortage cost per item and decision variables such as order quantity, safety factor, the number of shipments, and shipment increasing factor is figured out via sensitivity analysis. Finally, it is statistically proved that the mixed approach is superior to the existing approaches.

Effects on CO2 and NOx Emissions at Real Driving Condition in the Passenger Car using Gasoline Fuel with Various Engine Displacements (휘발유 승용자동차의 엔진 배기량이 실도로 주행시 이산화탄소 및 질소산화물 배출에 미치는 영향)

  • Lee, Jongtae;Kim, Hyung Jun;Lim, Yun Sung;Yun, Chang Wan;Keel, Ji Hoon;Hong, You Deug
    • Journal of ILASS-Korea
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    • v.23 no.3
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    • pp.122-127
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    • 2018
  • Recently, registrated passenger cars have increased and were close about seventy million at the end 2017 year in Korea. Among the passenger car using gasoline fuel make up forty six percentage of total registrated vehicles. In this study, investigation on real driving emission characteristics in the passenger car using gasoline fuel with various engine displacements were carried out. The real driving emission characteristics were measured and analyzed by using PEMS (Portable Emission Measurement System). PEMS was composed of gas analyzer, emission flow meter and sample conditioning system et al. Also, test six vehicles were selected to the gasoline passenger car with engine displacement from 1.6L to 3.7L. Two test routes with engine start of cold and hot conditions were applied to analyze the emission characteristics of RDE, respectively. The results show that the $CO_2$ emission have a increasing trend as the engine displacement and vehicle weight. Also, it is guessed that the $CO_2$ emission and vehicle weight were more correlated than the engine displacements. On the other hand, NOx emissions of RDE have not increasing or decreasing tendency according engine displacements or vehicle weight because the activation of three-way catalyst in the gasoline vehicles.

Feasibility Studies on Anaerobic Sequencing Batch Retractor for Sludge Treatment

  • Duk Chang;Joo
    • Journal of Environmental Science International
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    • v.1 no.2
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    • pp.125-136
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    • 1992
  • Digestion of a municipal wastewater sludge by the anaerobic sequencing batch reactor (ASBR) was investigated to evaluate the performance of the ASBR process at a critical condition of high-solids-content fined. The reactors were operated at an HRT of 10 days with an equivalent loading rate of 0.8-1.5 gVS/L/d at 35$^{\circ}C$ The main conclusions drawn from this study were as follows: 1. Digestion of a municipal wastewater sludge was possible using the ASBR in spite of high concentration of settleable solids in the sludge. The ASBRS with 3- and 4-day cycle period showed almost identical high digestion performances. 2. No adverse effect on digestion stability was observed In the ASBRS in spite of withdrawal and replenishment of 30% or 40% of liquid contents. A conventional anaerobic digester could be easily converted to the ASBR without any stability problem. 3. Flotation thickening occurred in thicken step of the ASBRS throughout steady state, and floating bed volume at the end of thicken period occupied about 70% of the working volume of the reactor Efficiency of flotation thickening in the ASBRS could be comparable to that of additional gravity thickening of a completely mixed digester. 4. Solids were accumulated rapidly in the ASBR during start-up period. Solids concentrations in the ASBRS were 2.6 times higher than that in the completely mixed control reactor at steady state. Dehydrogenase activity had a strong correlation with the solids concentration. Dehydrogenase activity of the digested flu형e in the ASBR was 2.9 times higher than that of the flu형e in the control reactor, and about 25 times higher than that of the subnatant in the ASBR. 5. Remarkable increase in equivalent gas production of 52% was observed at the ASBRS compared with the control reactor in spite of similar quality of clarified effluent from the ASBRS and control reactor. The increase in gas production from the ASBRS was believed to be combined results of accumulation of microorganisms, higher driving force applied, and additional long-term degradation of organics continuously accumulated.

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The Construction Work Completion of the Fuel Test Loop (핵연료 노내조사시험설비 설치공사 완료)

  • Park, Kook-Nam;Lee, Chung-Young;Chi, Dae-Young;Park, Su-Ki;Shim, Bong-Sik;Ahn, Sung-Ho;Kim, Hark-Rho;Lee, Jong-Min
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.291-295
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    • 2007
  • FTL(Fuel Test Loop) is a facility that confirms performance of nuclear fuel at a similar irradiation condition with that of nuclear power plant. FTL consists of In-Pile Test Section (IPS) and Out-Pile System (OPS). FTL construction work began on August, 2006 and ended on March, 2007. During Construction, ensuring the worker's safety was the top priority and installation of the FTL without hampering the integrity of the HANARO was the next one. Task Force Team was organized to do a construction systematically and the communication between members of the task force team was done through the CoP(community of Practice) notice board provided by the Institute. The installation works were done successfully overcoming the difficulties such as on the limited space, on the radiation hazard inside the reactor pool, and finally on the shortening of the shut down period of the HANARO. Without a sweet of the workers of the participating company of HEC(Hyundae Engineering Co, Ltd), HDEC(HyunDai Engineering & Construction Co. Ltd), equipment manufacturer, and the task force team, it is not possible to install the FTL facility within the planned shutdown period. The Commissioning of the FTL is on due to check the function and the performance of the equipment and the overall system as well. The FTL shall start operation with high burn up test fuels in early 2008 if the commissioning and licensing progress on schedule.

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Automatic Control System on Cardiac Output Regulation for the Moving Actuator Type Total Artificial Heart (MOVING-ACTUATOR TYPE 인공심장의 심박출 조절에 대한 자동 제어방법)

  • 김원곤
    • Journal of Chest Surgery
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    • v.28 no.6
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    • pp.542-548
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    • 1995
  • The goal of this study is to develop an effective control system for cardiac output regulation based upon the preload and afterload conditions without any transducers and compliance chambers in the moving actuator type total artificial heart. Motor current waveforms during the actuator movement are used as an input to the automatic control algorithm. While the current waveform analysis is performed, the stroke length and velocity of the actuator are gradually increased up to the maximum pump output level. If the diastolic filling rate of either right or left pump begins to exceed the venous return, atrial collapse will occur. Since the diastolic suction acts as a load to the motor, this critical condition can be detected by analyzing the motor current waveforms. Every time this detection criterion is met, the control algorithm decreases the stroke velocity and length of the actuator step by step just below the critical detection level. Then, they start to increase. In this way the maximum pump output under given venous return can be achieved. Additionally the control algorithm provides some degree of afterload sensitivity. If the aortic pressure is detected to exceed 120 mmHg, the stroke length and velocity decrease in the same way as the response to the preload. Left-right pump output balance is maintained by proper adjustment of the asymmetry of the stroke angle. In the mock circulatory test, this control system worked well and there was a considerable range of stroke volume difference with adjustment of the asymmetry value. Two ovine experiments were performed. It was confirmed that the required cardiac output regulation according to the venous return could be achieved with adequate detection of diastolic function, at least in the in vivo short-term survival cases[2-3 days . We conclude that this control algorithm is a promising method to regulate cardiac output in the moving actuator type total artificial heart.

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