• 제목/요약/키워드: Specific Processes

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심장 분자영상 (Cardiovascular Molecular Imaging)

  • 이경한
    • Nuclear Medicine and Molecular Imaging
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    • 제43권3호
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    • pp.229-239
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    • 2009
  • Molecular imaging strives to visualize processes in living subjects at the molecular level. Monitoring biochemical processes at this level will allow us to directly track biological processes and signaling events that lead to pathophysiological abnormalities, and help make personalized medicine a reality by allowing evaluation of therapeutic efficacies on an individual basis. Although most molecular imaging techniques emerged from the field of oncology, they have now gradually gained acceptance by the cardiovascular community. Hence, the availability of dedicated high-resolution small animal imaging systems and specific targeting imaging probes is now enhancing our understanding of cardiovascular diseases and expediting the development of newer therapies. Examples include imaging approaches to evaluate and track the progress of recent genetic and cellular therapies for treatment of myocardial ischemia. Other areas include in vivo monitoring of such key molecular processes as angiogenesis and apoptosis, Cardiovascular molecular imaging is already an important research tool in preclinical experiments. The challenge that lies ahead is to implement these techniques into the clinics so that they may help fulfill the promise of molecular therapies and personalized medicine, as well as to resolve disappointments and controversies surrounding the field.

식물의 생장과 분화 - 유전자. 홀몬. 환경의 조화 - (Plant Growth and Differentiation - Concerto for Hormones, Environment and Genes -)

  • 맹주선
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1987년도 식물생명공학 심포지움 논문집 Proceedings of Symposia on Plant Biotechnology
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    • pp.117-132
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    • 1987
  • Plants are inherited spatial and temporal coordination systems in their growth and differentiation processes which are precisely governed by the two interlocked control systems; autogenous and environmental. Looking into the overall course of plant development from molecular to organismal level, it can be comparable to a concerto for plant hormones, environmental stimuli and plant genomic orchestra conducted by an unidentified virtuoso. Some of the recent significant attempts to puzzle out the mystery of the life processes of plant development are briefly reviewed. The revolutionary advances in understanding the mystic processes are contemporarily achieved by the application of various molecular techniques. The characterization of plant genomes is now attained through recombinant DNA approaches, and the sensitive detection of specific gene products during the plant development is perimitted by the immunochemical procedures. However, along with the recognition of underlying molecular events such as developmental changes in gene expression and hormone-receptor interrelation associated with tissue sensitivity to hormones, more emphasis should be placed upon the physiological approaches of organismal level for the understanding the correlative systems of the developmental processes of plants as intact eukaryotic organisms.

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기업간 비즈니스 프로세스 메타데이터 온톨로지 설계 (B2B Business Process Metadata Ontology Design)

  • 김형도;김종우
    • 한국IT서비스학회:학술대회논문집
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    • 한국IT서비스학회 2006년도 추계학술대회
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    • pp.170-176
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    • 2006
  • B2B registries are information systems to registrate B2B related business information such as companies' profiles, business documents, business processes, services and to provide query facilities to find information about potential business partners. In this study, we focus on the design of the repository for B2B business processes. In this paper, a metadata ontology is designed to registrate B2B business processes. In practice, there are several competitive business process definition languages such as ebXML BPSS (Business Process Specification Schema), WSBPEL (Web Service Business Process Execution Language), BPMN (Business Process Modeling Notation), and so on. In order to registrate business processes based on different representation frameworks, the proposed metadata ontology consist of three layers, common metadata, language-specific metadata, and interrelationship metadata. To implement the proposed metadata ontology using ebXML registry, metadata mapping scheme to ebRIM (ebXML Registry Information Model) are also suggested.

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Process-Structure-Property Relationship and its Impact on Microelectronics Device Reliability and Failure Mechanism

  • Tung, Chih-Hang
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제3권3호
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    • pp.107-113
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    • 2003
  • Microelectronics device performance and its reliability are directly related to and controlled by its constituent materials and their microstructure. Specific processes used to form and shape the materials microstructure need to be controlled in order to achieve the ultimate device performance. Examples of front-end and back-end ULSI processes, packaging process, and novel optical storage materials are given to illustrate such process-structure-property-reliability relationship. As more novel materials are introduced to meet the new requirements for device shrinkage, such under-standing is indispensable for future generation process development and reliability assessment.

Decisional Balances and the Process of Change in Smoking Cessation in Patients with Coronary Artery Diseases

  • Son, Haeng-Mi
    • 대한간호학회지
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    • 제33권8호
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    • pp.1171-1177
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    • 2003
  • Purpose. Despite many smoking cessation programs, many patients with CAD continue to smoke or re-smoke. The processes of change and self-change for smoking cessation is emphasized. The purpose of present study was to investigate decisional balances and processes of change according to stages of change for smoking cessation in the patients with CAD. Methods. This descriptive study was performed using the self-reported questionnaires from 157 male patients with CAD who have smoking experiences. The questionnaires consisted of decisional balances toward smoking (pros/cons) and processes of change including 7 factors. Results. 45.2% of the subjects had myocardial infarction and 54.8% for angina pectoris. Major stages of change were maintenance, contemplation, and precontemplation in 62%, 14%, and 18% respectively. The mean score of pros smoking was 31.07 and cons smoking was 32.52. The mean scores of processes of change were high in all 7 factors, especially in self determination. The pros smoking in precontemplation stage was significantly higher than those in other stages. Between contemplation and precontemplation stages, processes of change showed significant differences in stimulus control, self determination, information management, and dramatic relief. Conclusion. This study suggests that decisional balances and processes of change are stage-specific. As this study, smoking cessation program in the patients with CAD must put priority on the patients group in pre-contemplation and contemplation stages, and stress self determination and dramatic relief.

무기체계 실사격 시험의 시스템공학 적용 (Systems Engineering based Live Fire Test of Weapon Systems)

  • 유병직;황규환;류충호;김문기;예성혁;한욱상
    • 한국군사과학기술학회지
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    • 제15권1호
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    • pp.28-35
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    • 2012
  • We propose the live fire test process model based on systems engineering which consists of 4 phases i.e., review, setup, conduct and result. We also suggest the 4 phases acquisition model consisting of planning, execution, evaluation and disposal for test infrastructure. CMMI, TMMi and PMBOK are referred and hierarchial analysis method are adopted in developing the models. Thus, the detailed sub-processes are designed after defining higher level processes first. The higher level processes are defined by extracting common areas of all the test types. The low level processes for each specific test are designed by tailoring the higher level processes. By applying the proposed test process models into collaboration tool and information system, effective and systematic test processes for weapon systems are established.

Development of Electrochemical Processes for Aluminium-Based Coatings for Fusion Applications

  • Konys, J.
    • Corrosion Science and Technology
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    • 제15권6호
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    • pp.314-319
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    • 2016
  • Reduced activation ferritic-martensitic steels (RAFM) are envisaged in future fusion technology as structural material which will be in direct contact with a flowing liquid lead-lithium melt, serving as breeder material. Aluminium-based coatings had proven their ability to protect the structural material from corrosion attack in flowing Pb-15.7Li and to reduce tritium permeation into the coolant, significantly. Coming from scales produced by hot dipping aluminization (HDA), the development of electrochemical-based processes to produce well-defined aluminium-based coatings on RAFM steels gained increased attention in research during the last years. Two different electrochemical processes are described in this paper: The first one, referred to as ECA, is based on the electrodeposition of aluminium from volatile, metal-organic electrolytes. The other process called ECX is based on ionic liquids. All three processes exhibit specific characteristics, for example in the field of processability, control of coating thicknesses (low activation criteria) and heat treatment behavior. The aim of this article is to compare these different coating processes critically, whereby the focus is on the comparison of ECA and ECX processes. New results for ECX will be presented and occurring development needs for the future will be discussed.

비표면적 인증표준물질 개발 (Development of Certified Reference Materials for Specific Surface Area)

  • 최병일;김종철;김태영;남현수;권수용
    • 분석과학
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    • 제18권1호
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    • pp.74-84
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    • 2005
  • NT, BT 산업의 발달에 함께 계면에서의 흡착특성의 파악은 신물질의 개발이나 공정의 첨단화에서 꼭 필요한 과제가 되고 있다. 체적식 가스흡착방법은 정량적인 흡착량의 측정이 가능하여 비표면적의 표준측정장비로 인식되고 있다. 상용 비표면적 측정장비의 신뢰성 검증을 위하여 인증표준물질을 개발하였고, SI 단위에 소급성을 유지하는 표준장비에 의해 불확도가 평가되었다. 제작된 인증물질은 비표면적이 $10.72{\pm}0.46m^2g^{-1}$ 인 silicon nitride 분말과 $149.50{\pm}3.44m^2g^{-1}$ 인 alumina 분말이다. 이런 검증된 인증물질의 보급은 산업계에 신뢰성 있는 비표면적 측정결과를 줌으로서, 일관성 있는 공정운용에 의한 품질관리, 생산성 향상, 안정성 판단 및 신제품 개발 등에 기여할 것이다.

Mechanism of E. coli RNA polymerase-promoter interactions

  • Roe, Jung-Hye;Record.Jr, M.Thomas
    • 미생물과산업
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    • 제13권1호
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    • pp.4-9
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    • 1987
  • The regulation of gene expression in procaryotes is accomplished primarily at the level of transcription. Initiation of transcription is subject to numerous promoter-specific controls which act to ensure coordinate expression of disparate genes. The kinetics of formation of a functional("open") complex at a promoter, prior to the catalytic steps of RNA chain initiation and elongation, is thought to play a major role in controlling the efficiency of transcription of that promotor, since the subsequent processes of nucleotide binding and phosphodiester bond formation are rapid and are not promoter-specific (Mangel and Chamberlin, 1974 Shimamoto et al., 1981)

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Ergodicity of Nonlinear Autoregression with Nonlinear ARCH Innovations

  • Hwang, S.Y.;Basawa, I.V.
    • Communications for Statistical Applications and Methods
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    • 제8권2호
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    • pp.565-572
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    • 2001
  • This article explores the problem of ergodicity for the nonlinear autoregressive processes with ARCH structure in a very general setting. A sufficient condition for the geometric ergodicity of the model is developed along the lines of Feigin and Tweedie(1985), thereby extending classical results for specific nonlinear time series. The condition suggested is in turn applied to some specific nonlinear time series illustrating that our results extend those in the literature.

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