• Title/Summary/Keyword: Spatial target

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Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin

  • Chaibangyang, Wanlapa;Geadkaew-Krenc, Amornrat;Vichasri-Grams, Suksiri;Tesana, Smarn;Grams, Rudi
    • Parasites, Hosts and Diseases
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    • v.55 no.6
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    • pp.643-652
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    • 2017
  • Calreticulin (CALR), a multifunctional protein thoroughly researched in mammals, comprises N-, P-, and C-domain and has roles in calcium homeostasis, chaperoning, clearance of apoptotic cells, cell adhesion, and also angiogenesis. In this study, the spatial and temporal expression patterns of the Opisthorchis viverrini CALR gene were analyzed, and calcium-binding and chaperoning properties of recombinant O. viverrini CALR (OvCALR) investigated. OvCALR mRNA was detected from the newly excysted juvenile to the mature parasite by RT-PCR while specific antibodies showed a wide distribution of the protein. OvCALR was localized in tegumental cell bodies, testes, ovary, eggs, Mehlis' gland, prostate gland, and vitelline cells of the mature parasite. Recombinant OvCALR showed an in vitro suppressive effect on the thermal aggregation of citrate synthase. The recombinant OvCALR C-domain showed a mobility shift in native gel electrophoresis in the presence of calcium. The results imply that OvCALR has comparable function to the mammalian homolog as a calcium-binding molecular chaperone. Inferred from the observed strong immunostaining of the reproductive tissues, OvCALR should be important for reproduction and might be an interesting target to disrupt parasite fecundity. Transacetylase activity of OvCALR as reported for calreticulin of Haemonchus contortus could not be observed.

Development of a Grid-Based Daily Land Surface Temperature Prediction Model considering the Effect of Mean Air Temperature and Vegetation (평균기온과 식생의 영향을 고려한 격자기반 일 지표토양온도 예측 모형 개발)

  • Choi, Chihyun;Choi, Daegyu;Choi, Hyun Il;Kim, Kyunghyun;Kim, Sangdan
    • Journal of Korean Society on Water Environment
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    • v.28 no.1
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    • pp.137-147
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    • 2012
  • Land surface temperature in ecohydrology is a variable that links surface structure to soil processes and yet its spatial prediction across landscapes with variable surface structure is poorly understood. And there are an insufficient number of soil temperature monitoring stations. In this study, a grid-based land surface temperature prediction model is proposed. Target sites are Andong and Namgang dam region. The proposed model is run in the following way. At first, geo-referenced site specific air temperatures are estimated using a kriging technique from data collected from 60 point weather stations. Then surface soil temperature is computed from the estimated geo-referenced site-specific air temperature and normalized difference vegetation index. After the model is calibrated with data collected from observed remote-sensed soil temperature, a soil temperature map is prepared based on the predictions of the model for each geo-referenced site. The daily and monthly simulated soil temperature shows that the proposed model is useful for reproducing observed soil temperature. Soil temperatures at 30 and 50 cm of soil depth are also well simulated.

Quantitative Risk Assessment Method for Metals in Water Body using WASP (WASP 모의를 이용한 하천 수계 중금속 위해성평가 방법)

  • Shin, Yu-Ri;Yoon, Chun-Gyeong;Jeon, Na-Jeong;Rhee, Han-Pil
    • Journal of Korean Society on Water Environment
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    • v.26 no.4
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    • pp.629-636
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    • 2010
  • According to the spatial movements of the Nak-dong river watershed, the changes in heavy metal concentrations were simulated by WASP7.3. The risk assessment was performed using the predicted data of WASP7.3. The target heavy metal was manganese (Mn). In the simulated manganese data of WASP7.3, the average concentration by regions was from 0.03 mg/L to 0.07 mg/L. It is lower than drinking water standard in korea. The risk assessment was presented that it was high at the junction of Nak-dong river and Kumho river. It was influenced by the discharge of industrial complexes and large cities which were located in the junction. In comparison of drinking water standard and predicted data of WASP7.3 risk assessment, whole watershed was also low level at predicted data. However, to keep the similar risk value ($10^{-7}$) in adults and children anywhere, it requires the additional treatment of the point source discharges. It was also reflected by regions. Through this study, it was possible to evaluate heavy metal influence in unattainable monitoring regions and to estimate heavy metal addition and reduction by locations. Therefore, the outcomes of WASP7.3 can connect with the risk assessment and it can evaluate the safety of human by regions.

Experimental Comparative Analysis of Terrestrial Lidar Data and Cadastral Data for the Calculation of the Slope Area of Highland Agriculture Region (고랭지 농업지역의 경지면적 산출을 위한 지상라이다 데이터와 지적성과의 실험적 비교 분석)

  • Lee, Ho-Hyun;Lee, Jung-Il;Oh, Min-Kyun;Lee, Kyung-Do
    • Journal of Cadastre & Land InformatiX
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    • v.46 no.2
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    • pp.137-153
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    • 2016
  • The price of agricultural products has changed from year to year, the m ajor c ause o f price fluctuation is the imbalance of supply and demand. Materials which are mainly used in korean cabbage production volume is the forecast model, using the cadastral result, slope calculation is impossible to achieved. For this reason, this implies the drastic decrease of prices and the prediction of supply and demand of field crops that is cultivated in a highland slope area, this situation is being repeated. Therefore, the target area of this research is the slopes of high land, by using 2D and 3D Lidar data for the analysis of the cultivated area. Experiment was carried out in the same area to compare the data differences. The rate of change in the area of slope is quantitatively increasing presented by the regression model. An alternative methodology that can improve the reliability of the calculated slope area using 2D is through cadastral map.

Gamma Knife Radiosurgery on Uveal Melanoma - Cases Report - (포도막 흑색종에 대한 감마나이프 방사선수술 - 증례보고 -)

  • Kim, Byung Wook;Kim, Moo Seong;Sim, Hong Bo;Jeong, Yeong Gyun;Lee, Sun Il;Jung, Yong Tae;Kim, Soo Chun;Sim, Jae Hong;Youn, Il Han;Kim, Young Il;Paik, Koang Ook
    • Journal of Korean Neurosurgical Society
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    • v.30 no.5
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    • pp.652-656
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    • 2001
  • Uveal melanoma is uncommon but life-threatening intraocular malignancy and has been treated by irradiation, local excision and enucleation. Gamma-Knife radiosurgery allows a high dose of radiation to be delivered to an intracranial target with a very high spatial accuracy and has been used for the treatment of ocular melanomas. We have treated two cases of uveal melanoma between October 1994 and December 1999. They include one man and one woman(34, 62 years, respectively). They were followed up for 12 momths. Mean maximal dose was 65Gy. In one case, the tumor disappeared 7 months after gamma-knife radiosurgery. In another case, multiple tumors (uveal, suprasellar and cerebellar tumor) had decreased in size. These results show that single and high dose gamma-knife radiosurgery is may be an option in the local control of uveal melanoma which can spare the eyeball and vision.

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A Single Cell Multimedia Fate Model for Endocrine Disrupting Chemicals

  • Park, Kyunghee;Junheon Youn;Daeil Kang;Lee, Choong;Lee, Dongsoo;Jaeryoung Oh;Sunghwan Jeon;Jingyun Na
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2003.05a
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    • pp.149-149
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    • 2003
  • To understand environmental paths of the transport and accumulation of endocrine disrupting chemicals (EDCs), a single cell multimedia fate model has been constructed and evaluated. The EDCs of concern were PAHs, Organochlorine Pesticides (OCPs), PCBs, Alkyl phenols, and phthalates. An evaluation model was designed for the multimedia distribution, including air, water, soil, sediment and vegetation. This model was verified using reported values and via monitoring data. Based on collected data, the distribution trends of EDCs with respect to environmental media were analyzed. Those results have applied to the model for the prediction of the spatial and temporal distribution of EDCs in Seoul. Especially, phenol compound, phthalates, PAHs, PCBs and organochlorine pesticides were estimated and the model was verified. This model was successfully conducted to environmental media, such as air (vapor and suspended particles), soils (forest soil, bare soil, and cement-concrete covered soil), water (dissolved and suspended solids), sediment, trees (deciduous and coniferous). The discrepancies between the model prediction and the measured data are approximately within or near a factor of 10 for the PAHs of three rings through that of six rings, implying that multimedia distribution of the PAHs could be predicted with a factor of 10. Concerning about the air equilibrium may be assumed, a fugacity at steady state is similar in all environmental media. Considering the uncertainties of this model, the use of equilibrium models may be sufficient for assessing chemical fates. In this study, a suggestion was made that modeling and estimation of chemicals in environmental multimedia be rigorously evaluated using the measured flux data. In addition, these data should be obtained, for example, from the precise and standardized inventory of the target chemicals. The model (EDC Seoul) will be refined in an on-going research effort and will be used to support decision-making concerning the management of EDCs.

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Determination factors for catch rate of the target species between circle hook and straight shank hook in the Korean tuna longline fishery (우리나라 다랑어연승어업에 있어서 환형낚시와 재래식낚시를 사용하여 목표종의 어획률을 결정하는 요인 분석)

  • An, Doo-Hae;Kwon, You-Jung;Bigelow, Keith;Moon, Dae-Yeon;Lee, Sung-Il
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.47 no.4
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    • pp.344-355
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    • 2011
  • We conducted experiments to compare the catch rate of bigeye tuna and yellowfin tuna between circle hooks and straight shank hook in the Korean tuna longline fishery at the eastern and central Pacific Ocean from 2005 to 2007. We analyzed difference of fork length, survival and hooking location between a circle hook and a straight shank hook for both tunas, respectively. There was no difference in the mean fork length size of yellowfin tuna caught on the two type of hook but bigeye tuna was significant. In case of survival, there was no difference between two hook type, but the difference of hooking location was significant for both species. We also analyzed to find determinants of both tunas catch rate using generalized linear models (GLMs) which were used latitude, longitude, year, month, depth, hook type, bait type and so on as independent variables. Spatial factors, latitude and longitude, and temporal factors, year and month, affected catch rate of bigeye tuna and yellowfin tuna. And also, depth such as a marine environment factor was influenced on catch rate.

Micro-scale Public Transport Accessibility by Stations - KTX Seoul Station Case Study - (정류장 단위의 미시적 대중교통 접근성 분석 - KTX 서울역 사례연구 -)

  • Choi, Seung U;Jun, Chul Min;Cho, Seong Kil
    • Journal of Korean Society for Geospatial Information Science
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    • v.24 no.1
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    • pp.9-16
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    • 2016
  • As the need of eco-friendly transportation systems for sustainable development increases, public transport accessibility has been considered as an important element of transportation system design. When analyzing the accessibility, shortest path algorithms can be utilized to reflect the actual movement and we can obtain high resolution accessibility for all other stations on the network with shortest distance and time. This study used the algorithm improved by reflecting the penalty of number of transfers and waiting time of overlapped routes to get the accessibility. KTX Seoul Station is a target place and this algorithm is applied to multi-layer subway bus network of Seoul to calculate the accessibility, therefore this study presented the accessibility of KTX Seoul station by stations.

Evaluation of Water Quality for the Han River Tributaries Using Multivariate Analysis (다변량 통계 분석기법을 이용한 한강수계 지천의 수질 평가)

  • Kim, Yo-Yong;Lee, Si-Jin
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.7
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    • pp.501-510
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    • 2011
  • In this study, water pollution sources of 14 major tributaries of Han river and characteristics of water quality for each target streams were evaluated based on water quality data in 2007.1-2009.12 (14 data sets) using a statistical package, SPSS-17.0. Cluster analysis over time and space for each stream resulted in 4 groups for the spatial variations in which type and density of pollution sources in the basins showed the greatest impact on grouping. Moreover, cluster analysis for the time variation in which rainfall, temperature and eutrophication were shown to contribute to the clustering, produced 2 groups, from summer to fall (July-Oct.) and from winter to early summer (Nov.-June). Four factors were found as responsible for the data structure explaining 71-90% of the total variance of the data set depending on the streams and they were organic matter, nutrients, bacterial contamination. Factor analysis showed main factors (water pollutants) changed according to the season with different pattern for each stream. This study demonstrated that water quality of each stream could produce useful outcomes when factor and pollution source of basin were evaluated together.

A Study on Contents-based Retrieval using Wavelet (Wavelet을 이용한 내용기반 검색에 관한 연구)

  • 강진석;박재필;나인호;최연성;김장형
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.5
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    • pp.1051-1066
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    • 2000
  • According to the recent advances of digital encoding technologies and computing power, large amounts of multimedia informations such as image, graphic, audio and video are fully used in multimedia systems through Internet. By this, diverse retrieval mechanisms are required for users to search dedicated informations stored in multimedia systems, and especially it is preferred to use contents-based retrieval method rather than text-type keyword retrieval method. In this paper, we propose a new contents-based indexing and searching algorithm which aims to get both high efficiency and high retrieval performance. To achieve these objectives, firstly the proposed algorithm classifies images by a pre-processing process of edge extraction, range division, and multiple filtering, and secondly it searches the target images using spatial and textural characteristics of colors, which are extracted from the previous process, in a image. In addition, we describe the simulation results of search requests and retrieval outputs for several images of company's trade-mark using the proposed contents-based retrieval algorithm based on wavelet.

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