Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Gamma Knife Radiosurgery on Uveal Melanoma - Cases Report -

포도막 흑색종에 대한 감마나이프 방사선수술 - 증례보고 -

  • Kim, Byung Wook (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Kim, Moo Seong (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Sim, Hong Bo (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Jeong, Yeong Gyun (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Lee, Sun Il (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Jung, Yong Tae (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Kim, Soo Chun (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Sim, Jae Hong (Department of Neurosurgery, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Youn, Il Han (Department of Ophthalmology, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Kim, Young Il (Department of Ophthalmology, College of Medicine, Inje University Pusan Paik Hospital) ;
  • Paik, Koang Ook (Department of Ophthalmology, College of Medicine, Inje University Pusan Paik Hospital)
  • 김병욱 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 김무성 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 심홍보 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 정영균 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 이선일 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 정용태 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 김수천 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 심재홍 (인제대학교 의과대학 부산백병원 신경외과학교실) ;
  • 윤일한 (인제대학교 의과대학 부산백병원 안과학교실) ;
  • 김영일 (인제대학교 의과대학 부산백병원 안과학교실) ;
  • 백광욱 (인제대학교 의과대학 부산백병원 안과학교실)
  • Received : 2000.10.20
  • Accepted : 2001.04.20
  • Published : 2001.05.28
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Abstract

Uveal melanoma is uncommon but life-threatening intraocular malignancy and has been treated by irradiation, local excision and enucleation. Gamma-Knife radiosurgery allows a high dose of radiation to be delivered to an intracranial target with a very high spatial accuracy and has been used for the treatment of ocular melanomas. We have treated two cases of uveal melanoma between October 1994 and December 1999. They include one man and one woman(34, 62 years, respectively). They were followed up for 12 momths. Mean maximal dose was 65Gy. In one case, the tumor disappeared 7 months after gamma-knife radiosurgery. In another case, multiple tumors (uveal, suprasellar and cerebellar tumor) had decreased in size. These results show that single and high dose gamma-knife radiosurgery is may be an option in the local control of uveal melanoma which can spare the eyeball and vision.

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