• Molecules and Cells
• /
• v.43 no.7
• /
• pp.591-599
• /
• 2020

Complex cell-to-cell communication underlies the basic processes essential for homeostasis in the given tissue architecture. Obtaining quantitative gene-expression of cells in their native context has significantly advanced through single-cell RNA sequencing technologies along with mechanical and enzymatic tissue manipulation. This approach, however, is largely reliant on the physical dissociation of individual cells from the tissue, thus, resulting in a library with unaccounted positional information. To overcome this, positional information can be obtained by integrating imaging and positional barcoding. Collectively, spatial transcriptomics strategies provide tissue architecture-dependent as well as position-dependent cellular functions. This review discusses the current technologies for spatial transcriptomics ranging from the methods combining mechanical dissociation and single-cell RNA sequencing to computational spatial re-mapping.

• Spatial Information Research
• /
• v.10 no.3
• /
• pp.421-438
• /
• 2002

Abstraction of geographic data within a spatial database context must deal with geometrical simplification, modification or maintenance of the integrity of features, spatial and aspatial data, topology within class, and relationships between classes. This research is to propose a method to abstract a spatial database into a high level database. This study refines operators to carry out the modifications required by the abstraction process in the spatial database. Then, a set of operator sequences (workflows) is suggested to specify operators required to abstract a given feature class and to arrange them in order. Finally, a prototype system is developed, based on rule management with a graphic user interface. When the abstraction process is implemented sequentially we demonstrate that a preferential ordering of operations improves efficiency and reduces loss and distortion in the information.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
• /
• 2007.04a
• /
• pp.295-299
• /
• 2007

Today, ubiquitous technology (e.g. computers or networked devices pervade everywhere we are) has enlarged by great advancement of information and communication technologies. If ubiquitous technologies is applied to, innovation of spatial information technology is expected. traditional spatial information technologies such as survey, GIS, GPS, LBS, and RS and ubiquitous technology gradual1y have been converged. The aim of this study is to create shared visions in spatial information technologies by scenario based roadmapping. So, we surveyed the state of the art in main spatial information technologies, market status and patent map. Consequently, prospects of spatial information technologies is suggested. The aim of 1st and 2nd NGIS project focused on map supplier was to develop digital map(e.g. framework data, various thematic map). As a result, the best technology of digital mapping is achieved in the world. But, there is not enough to develop GIS and LBS solution. Current market in GIS S/W and Telematics is about 384billon won and 250billion won. a patent is applied in the order, like a USA(1571case, 47%), Japan(883case, 26%), EU(478case, 14%), Korea(446case, 13%). In the future, spatial information technology fused on ubiquitous technology will be focused on user's demand and developing convenience context. The developing target will be realtime monitoring of 3D spatial data based on high resolution coordinate system, sharing and supplying multi-sensor data considered users demand, location service by ubiquitous technologies.

• Spatial Information Research
• /
• v.19 no.3
• /
• pp.83-93
• /
• 2011

Since urban facilities have a signigicant meaning that represents the degree of development of nations and cities, it is very important to effectively manage and operate the facilities. In this paper, we propose a context-awareness system for managing urban underground facilities intelligently and develop its algorithm and prototype. The algorithm of the suggested system includes the period from the point when various sensors set up in USN environments sense abnormal signals and make alarms to the point when the context-awareness system analyzes the alarm and sends the analysis results to integrated platform and related modules. We then implement the prototype of the proposed context awareness system and verify the effectiveness of the system by performing unit tests. Our developed prototype will become the basis of actual system development. We expect that the suggested system will be used as a good reference model of related systems managing various types of urban facilities.

• Animal cells and systems
• /
• v.2 no.1
• /
• pp.65-69
• /
• 1998

The hippocampus and prefrontal cortex are regarded as the highest-order association cortices. The hippocampus has been proposed to store "cognitive maps" of external environments, and the prefrontal cortex is known to be involved in the planning of behavior, among other functions. Considering the prominent functional roles played by these structures, it is not surprising to find direct monosynaptic projections from the hippocampus to the prefrontal cortex. Rhythmic stimulation of this projection patterned after the hippocampal EEG theta rhythm induced stable long-term potentiation of field potentials in the prefrontal cortex. Comparison of behavioral correlates of hippocampal and prefrontal cortical neurons during an a-arm radial maze, working memory task shows a striking contrast. Hippocampal neurons exhibit clear place-specific firing patterns, whereas prefrontal cortical neurons do not show spatial selectivity, but are correlated to different stages of the behavioral task. These data lead to the hypothesis that the role of hippocampal projection to the prefrontal cortex is not to impose spatial representations upon prefrontal activity, but to provide a mechanism for learning the spatial context in which particular behaviors are appropriate.propriate.

• Korean Journal of Computational Design and Engineering
• /
• v.16 no.6
• /
• pp.437-448
• /
• 2011

A robotic spatial augmented reality (RSAR) system combines a robotics technology with a spatial augmented reality system (SAR) where cameras are used to recognize real objects and projectors augment information and user interface directly on the surface of the recognized objects, rather than relying on handheld display devices. Moreover, a robotic module is actively used to discover and utilize the context of users and environments. The control of a RSAR system involves several issues from different technical fields such as classical inverse kinematics of motors where projector-camera pairs are mounted, inverse projection problems to find appropriate internal/external parameters of projectors and cameras, and image warping in graphics pipeline to compensate the kinematic constraints. In this paper, we investigate various control issues related to a RSAR system and propose basic approaches to handle them, specially focused on the prototype RSAR system developed in ETRI.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 2003.09a
• /
• pp.459-462
• /
• 2003

Selectivity estimation of queries not only provides useful information to the query processing optimization but also may give users with a preview of processing results. In this paper, we investigate the problem of selectivity estimation in the context of a spatial dataset. Although several techniques have been proposed in the literature to estimate spatial query result sizes, most of those techniques still have some drawback in the case that a large amount of memory is required to retain accurate selectivity. To eliminate the drawback of estimation techniques in previous works, we propose a new method called MW Histogram. Our method is based on two techniques: (a) MinSkew partitioning algorithm that processes skewed spatial datasets efficiently (b) Wavelet transformation which compression effect is proven. We evaluate our method via real datasets. With the experimental result, we prove that the MW Histogram has the ability of providing estimates with low relative error and retaining the similar estimates even if memory space is small.

• 제어로봇시스템학회:학술대회논문집
• /
• 2005.06a
• /
• pp.31-36
• /
• 2005

Intelligent Space (iSpace) is the space where many intelligent devices, such as computers and sensors, are distributed. According to the cooperation of many intelligent devices, the environment comes to have intelligence. In iSpace, the locations of multiple humans and other objects are obtained and tracked by using multiple camera and color-based method. In addition, we describe a context-aware information system which is based on Spatial-Knowledge-Tags (SKT). SKT system enables humans to access information and data by using spatial location of human and stored information in storage. The proposed tracking method is applied to the intelligent environment and its performance is verified by the experiments.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.22 no.4
• /
• pp.515-520
• /
• 2012

In brain computer interface (BCI) system, the most important part is classification of human thoughts in order to translate into commands. The more accuracy result in classification the system gets, the more effective BCI system is. To increase the quality of BCI system, we proposed to reduce noise and artifact from the recording data to analyzing data. We used auditory stimuli instead of visual ones to eliminate the eye movement, unwanted visual activation, gaze control. We applied independent component analysis (ICA) algorithm to purify the sources which constructed the raw signals. One of the most famous spatial filter in BCI context is common spatial patterns (CSP), which maximize one class while minimize the other by using covariance matrix. ICA and CSP also do the filter job, as a raw filter and refinement, which increase the classification result of linear discriminant analysis (LDA).

• Journal of Korean Society for Geospatial Information Science
• /
• v.5 no.2 s.10
• /
• pp.55-63
• /
• 1997

Precision digital data capture and spatial analysis system to cultural properties play important roles in preserving the existing properties. This study presents the acquisition oi digital data in geometrical context and spatial analysis for more effective management to cultural properties. Established in the same coordinates system, Precision 3D measurements and image analysis were peformed. In addition, geometrical analysis, and 3D monitoring to Songsanri Royals Tombs in Gongju were carried out in generating basedata for conservation plan.