• 한국균학회지
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• 제40권4호
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• pp.183-186
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• 2012

곰솔(Pinus thunbergii Parl.)의 잎에 서식하는 내생균의 다양성을 확인하기 위하여 충남 보령의 해안가에 서식하는 곰솔에서 잎을 채취하여 총 19개의 균주를 분리하였다. 분리된 내생균을 ITS 지역과 LSU 지역의 염기서열을 분석하여 동정한 결과 Anthostomella sepelibilis, Beltrania sp., Cladosporium sp., Coniochaeta velutina, Entonaema pallida, Lophodermium sp., Nigrospora sphaerica 등 총 7개 분류군의 내생균을 확보할 수 있었다. 이들 중 Beltrania sp.에 속하는 종이 가장 높은 빈도로 분리되었으며 내생균의 서식 환경이 곰솔의 잎에 서식하는 내생균의 분포에 영향을 미칠 수 있음을 확인하였다.

• 한국균학회지
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• 제40권4호
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• pp.277-281
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• 2012

고추포장의 토양에서 분리한 Bacillus sp. NAAS-1 Colletotrichum acutatum에 대한 생물학적 방제 활성을 검정 하였다 이 분리균주를 일종의 작물보호제인 카밴다짐 가스가마이신 수화제와 비교하여 검정한 결과, 기준사용량 농도(50 ${\mu}L/mL$)와 비슷한 항진균 활성을 나타냈다. 또한 생물 검정 결과, 공시 작물보호제의 기준사용량 농도(50 ${\mu}L/mL$)에서 보다 고추 탄저병균의 발병억제효과가 높게 나타나내었다.

• BMB Reports
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• 제47권7호
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• pp.411-416
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• 2014

In the present study, we demonstrate that ectopic expression of 56-kDa human selenium binding protein-1 (hSP56) in PC-3 cells that do not normally express hSP56 results in a marked inhibition of cell growth in vitro and in vivo. Down-regulation of hSP56 in LNCaP cells that normally express hSP56 results in enhanced anchorage-independent growth. PC-3 cells expressing hSP56 exhibit a significant reduction of hypoxia inducible protein (HIF)-$1{\alpha}$ protein levels under hypoxic conditions without altering HIF-$1{\alpha}$ mRNA (HIF1A) levels. Taken together, our findings strongly suggest that hSP56 plays a critical role in prostate cells by mechanisms including negative regulation of HIF-$1{\alpha}$, thus identifying hSP56 as a candidate anti-oncogene product.

• 대한기계학회논문집A
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• 제28권5호
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• pp.554-562
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• 2004

An empirical relationship between parameters from SP curves and tensile properties has been systematically investigated by experimental tests and FEM simulations. A series of SP and tensile tests were performed. SP tests were also simulated by FE analysis with various tensile properties. It was found that the yield loads(Py) and the maximum loads( $P_{MAX}$) in SP curves were linearly related with the yield strength($\sigma$$_{o}$) and the tensile strength($\sigma$$_{UTS}$), respectively. The yield loads defined from the intersection point of two lines tangent to the elastic bending region and plastic bending region showed better relation to the yield strength than those from offset line. The maximum loads in SP curves showing plastic instability region was linearly related with the tensile strengths. The slope of SP curves in simulation results had a close correlation with the hardening coefficient and hardening strength as well.l.l.l.

• 한국진공학회지
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• 제12권S1호
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• pp.113-115
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• 2003

We investigate transmission of light in nanoscale structures. We present spatial and temporal domain measurements of the dephasing of surface plasmon excitations in metal films with periodic nano-hole arrays. By probing coherent spatial SP propagation lengths of a few f1. $\mu$m and an ultrafast decay of the SP polarization on a 10 fs timescale, we demonstrate that the SP transmission peaks are homogeneously broadened by the SP radiative lifetime. The pronounced wavelength and hole size dependence of the dephasing rate shows that the microscopic origin of the conversion of SP into light is a Rayleigh-like scattering by the periodic hole array. We have experimentally studied the dephasing of surface plasmon excitations in metallic nano-hole arrays. By relating nanoscopic SP propagation, ultrafast light transmission and optical spectra, we demonstrate that the transmission spectra of these plasmonic bandgap structures are homogeneously broadened. The spectral line shape and dephasing time are dominated by Rayleigh scattering of SP into light and can varied over a wide range by controlling the resonance energy and/or hole radius. This opens the way towards designing SP nano-optic devices and spatially and spectrally tailoring light -matter interactions on nanometer length scales.

• 한국의사학회지
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• 제29권1호
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• pp.103-116
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• 2016

The location of BL61 has commonly known as directly under the BL60 (Gollyun) which is at the lateral side of the heel. SP2 is located at the front of the big toe joint and SP3 is located at the rear of the big toe joint. These locations are the same with the standard acupuncture points of the WHO/WPRO. However, according to Chimgeumdongin (鍼金銅人), BL61 is located at the center of calcaneal tuberosity, which is close to the bottom of the heel, not at the side. SP2 is located at the rear of the big toe joint, not at the front. SP3 is located at the rear of sesamoid bone, not at the rear of the big toe joint. These can be also found in Douningyou (銅人形) c-544 with the same locations. Moreover, these locations are precisely equal in reference to the acupuncture classics such as < Zhenjiujiayijing : 鍼灸甲乙經 >, < Buzhutongrenjing : 補註銅人經 >, whereas the descriptions of the standard acupuncture points of the WHO/WPRO and the locations of acupuncture points in Zhenjiutongren (鍼灸銅人), Zhinjiuxueweitongren (鍼灸穴位銅人) are totally different from the acupuncture classics. Therefore, there needs to be further examinations on WHO/WPRO Standard Acupuncture Point with various acupuncture bronze men.

• Restorative Dentistry and Endodontics
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• 제28권5호
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• pp.409-418
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• 2003

본 연구는 치수 염증 시 IL-8과 MCP-1 분비에서 neuropeptide의 역할에 대해 관찰하고자 발거된 건전한 치아를 수직 파절시켜 치수조직을 채취하여 배양된 치수세포 및 혈관내피세포(ECV 304세포)를 각기 다른 농도의 Substance P(SP)로 12시간 자극하였고, 24시간 동안 4시간 간격으로 시간대별로 자극하였으며, 또 치수세포를 Calcitonin gene-related peptide (CGRP)로 12시간 자극하였다. 이들 세포를 SP길항제 (Spantide)로 15분간 차단한 후 SP로 12시간 재 자극하였으며, SP와 CGRP혼합액을 12시간 자극하였다. 상기의 실험 후 부유물로 ELISA를 시행하여 IL-8과 MCP-1의 분비 량을 측정하였다. 치수세포는 SP로 자극 시 IL-8이 현저히 증가한 반면, CGRP는 효과가 없었으며, SP와 CGRP를 혼합자극 시 시너지 효과 또한 없었고, Spantide는 치수세포의 IL-8과 MCP-1의 분비를 차단시켰다. 치수세포를 SP로 24시간 동안 4시간 간격으로 자극 시 8시간 후 최대의 IL-8은 분비량 나타내었으며, 8시간과 12시간 사이에서 최대의 MCP-1 분비량을 나타내었다. ECV 304세포를 SP로 자극 시 IL-8과 MCP-1 분비량이 미약하게 증가하였으며, Spantide는 ECV 304세포의 IL-8과 MCP-1 분비를 억제시켰다.

• Journal of Power Electronics
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• 제17권6호
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• pp.1563-1576
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• 2017

This paper presents a novel switching pattern current control (SP-CC) scheme, which is applied in three-phase voltage-source converters (VSCs). This scheme can select the optimal output switching pattern (SP) by referring the basic principle of space vector modulation (SVM). Moreover, SP-CC is a method without a carrier wave. Thus, the implementation process is concise and easy. When compared with the conventional hysteresis current control (C-HCC) and the space vector-based hysteresis current control (SV-HCC), the SP-CC has the performances of faster dynamic response of C-HCC and less switching number (SN) of SV-HCC. In addition, it has less harmonic contents in the three-phase current, along with a lower switching loss and a higher efficiency. Moreover, the hysteresis bandwidth and Clarke conversion are not required in the SP-CC. The effectiveness of the presented SP-CC is verified by simulation and experimental test results. In addition, the advantages of the SP-CC, when compared with the C-HCC and SV-HCC, are verified as well.

• 한국유기농업학회지
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• 제27권1호
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• pp.57-63
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• 2019

Ricania sp. is a pest to many crops in Korea. This pest prefers fruit crops especially, blueberry and apple trees. We tested the possibility of Ricania sp. control using of methylcinnamate. In the laboratory bioassay, the mortality of methylcinnamate against Ricania sp. adult with 100 and 250 time diluted solution was 36.6% and 13.3% respectively. While repellent that the use of methylcinnamate resulted rate of 43.3% with 100 time diluted solution and 40.0% in 250 time diluted solution. Insecticidal and repellent effect in semifield bioassay were higher than those in laboratory bioassay. From this result, methylcinnamate might have synergic effect for Ricania sp. management. The result of this study showed a possibility of Ricania. sp. control using methylcinnamate.

• 한국임상약학회지
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• 제32권1호
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• pp.8-12
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• 2022

Background: Woosuk University College of Pharmacy delivered patient counseling education and administered Objective Structured Clinical Examination (OSCE) by utilizing standardized patients (SP) in Introductory Pharmacy Practice course. Surveys were conducted to examine students' perception of SP and its impact on experiential education. Methods: Students learned patient counseling by didactic lecture and role-play, followed by hands-on practice with SP. Then, patient counseling skills were assessed during OSCE by utilizing SP. The first survey was conducted immediately after OSCE, and the second survey after the completion of Pharmacy Practice Experiences (PPEs). Results: According to the surveys, majority of the students agreed that utilizing SP was effective in building confidence for conducting patient counseling, reflecting on strengths and weaknesses of communication skills, and preparing for PPEs. It was particularly more effective than role-play in simulating patient counseling in a real pharmacy and reflecting on oneself. Also, OSCE was an appropriate method to assess patient counseling skills and utilizing SP for this purpose was well-suited. Conclusion: Although it is very new in South Korea, other developed countries are already widely utilizing SP, and its importance and necessity have been proven by several studies. Therefore, Korean colleges of pharmacy should begin discussing how to utilize SP to improve students' communications skills and implementing OSCE to evaluate those skills.